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| 1 | 选择性CD_(34)^+细胞和非选择性自体外周血干细胞移植治疗多发性骨髓瘤的比较研究显示文摘目的 明确选择性CD3 4+ 细胞自体外周血干细胞移植 (APBSCT)治疗多发性骨髓瘤 (MM)的临床效果。方法 对 2 1例接受CD3 4+ 细胞APBSCT治疗的MM患者 (选择组 )和另外 2 1例接受非选择性APBSCT的MM患者 (对照组 )的造血恢复时间、有效率、生存率、移植相关不良反应、移植费用进行比较。两组病例在年龄、初诊时血清 β2 微球蛋白水平和移植时疾病状态均具有可比性 ,诱导治疗及预处理方案基本相同。结果 与对照组相比 ,选择组患者回输的CD3 4+ 细胞数显著偏低 [对照组和选择组分别为 9.4(1.1~ 15 .0 )× 10 6/kg和 2 .2 (0 .5~ 14.3)× 10 6/kg](P <0 .0 0 1) ,中性粒细胞恢复至≥ 0 .5× 10 9/L和血小板恢复至≥ 2 0× 10 9/L的中位时间 ,在选择组分别为 10d和 9d ,对照组分别为 9.5d(P=0 .35 7)和 4.5d(P =0 .0 0 5 )。两组的治疗有效率相似 (选择组 85 .7% ,对照组 90 .4% ) ,3年无病生存率 (选择组和对照组分别为 32 %和 39% )和总生存率 (选择组和对照组分别为 85 %和 79% )两组相比差异无显著性 ,而且使用非选择性APBSCT可明显降低移植费用。结论 选择性CD3 4+ 细胞APBSCT与非选择性APBSCT相比 ,并不能改善MM的临床治疗结果 ,而且移植费用更大。 | 唐晓文 N Morineau N Milpied P Moreau R Bataille JL Harousseau | 2001 | 中华血液学杂志2001，22，7： | 5 |
| 2 | Audio classification based on MPEG-7 spectral basis representations显示文摘 | Kim H-G Moreau N Sikora T | 2004 | IEEE Transactions on Circuits and Systems for Video Technology2004，14，5： | 1 |
| 3 | Longitudinal study of bacterial,viral,and fungal infections in adult recipients of bone marrow transplants显示文摘 | Ninin E Milpied N Moreau P | 2001 | Clin Infect Dis2001，33，： | 1 |
| 4 | Ethylbenzene Isomer- ization over Bifunctional Platinum Alumina-EUO Catalysts: Location of the Active Sites 显示文摘 | Moreau F Moreau P Gnep N S | 2006 | Microporous Mesoporous Mater2006，90，13： | 1 |
| 5 | Workshop: excess growth and apoptosis: is hyper- tension a case of accelerated aging of cardiovascular cells? 显示文摘 | Hamet P Thorin-Trescases N Moreau P Dumas P Tea BS de- Blois D | 2001 | Hypertension2001，37，22： | 1 |
| 6 | Nonorthogonal joint diagonalization/zero diagonalization for source separation based on time-frequency distributions 显示文摘 | Fadaili E M Moreau N T Moreau E | 2007 | Signal Processing2007，55，5： | 1 |
| 7 | hazomib, an investigational oral proteasome inhibitor ( PI ), in combination with lenalidomide and dexamethasone ( IRd ), significantly extends progression-free survival ( PFS ) for patients ( Pts ) with relapsed and/or refractory multiple myeloma ( RRMM ) : the phase 3 tourmaline-MM1 study ( NCT01564537 ) 显示文摘 | Moreau P Masszi T Grzasko N | 2015 | Blood2015，126，23： | 1 |
| 8 | beta-Dystroglycan can be revealed in microsomes from mdx mouse muscle by detergent treatment显示文摘 | Cluchague N Moreau C Rocher C | 2004 | FEBS Lett2004，572，13： | 1 |
| 9 | Proten nuclear magnetic study of bistramide A,a new cytotoxic drug isolated from Lissoclmum bistratum显示文摘 | Gouifes D Moreau S Helbecque N el al | 1998 | Tetrahedron1998，44，2： | 1 |
| 10 | HLA-G, -E, -F preworkshop:tools and protocols for analysis of non-classical class Ⅰ genes transcription and protein expression显示文摘 | Paul P Rouas-Freiss N Moreau P | 2000 | Hum Immunol2000，61，11： | 1 |
| 11 | Respiratory toxicity of multi-wall carbon nanotubes显示文摘 | Muller J Huaux F Moreau N | 2005 | Toxicol Appl Pharmacol2005，207，3： | 1 |
| 12 | Immunopheno-type of normal and myelomatous plasma-cell subsets显示文摘 | Robillard N Wuilleme S Moreau P Bene M C | 2014 | Front Immunol2014，5，： | 1 |
| 13 | Ethylbenzene isomeri- zation over bifunctional platinum alumina-EUO catalysts:Lo- cation of the active sites显示文摘 | Moreau F Moreau P Gnep N S | 2006 | Microporous Mesoporous Ma- ter2006，90，123： | 1 |
| 14 | A nonunitary joint block diagonalization algorithm for blind separation of convolutive mixtures of sources显示文摘 | Ghennioui H Fadaili E M Moreau N T | | 0，，11： | 1 |
| 15 | HIA-G,-E,-F preworkshop:took and protocolsfor anelysisof non-classical class I genestranscrition and protein expression显示文摘 | Rouas-Freiss N Moreau P et e1 | 2000 | Hum Immunol2000，61，11： | 1 |
| 16 | A QTL affecting milk yield and composition maps to bovine chromosome 20: A confirmation 显示文摘 | Arranz J J Coppieters W Berzi P Cambisano N Grisart B Karim L Marcq F Moreau L Mezer C Riquet J Simon P Vanmanshoven P Wagenaar D and Georges M | 1998 | Animal Genetics1998，29，： | 1 |
| 17 | Synthesis and biological evaluation of acyclic triaryl (Z)-olefins possessing a 3,5-ditert-butyl-4-hydroxyphenyl pharmacophore: dual inhibitors of eyelooxygenases and lipoxygenases显示文摘 | Moreau A Rao P N Knaus E E | 2006 | Bioorg Med Chem2006，14，15： | 1 |
| 18 | Ethylbenzene isomerization over bifunctional platinum alumina-EUO catalysts: Location of the active sites显示文摘 | MOREAU F MOREAU P GNEP N S | 2006 | Micropor and Mesopor Mater2006，90，： | 1 |
| 19 | The Kallikrein - Kinin System:Current and Future Pharmacological Targets 显示文摘 | Moreau ME Garbacki N Molinaro G | 2005 | J Pharmacol Sci2005，99，1： | 1 |
| 20 | Access to health care for induced abortions analysis by means of a French national survey显示文摘 | Moreau C bajos N Bouyer J | 2004 | Eur J Public Health2004，14，4： | 1 |
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