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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Interesting physical properties of the new spinel phase of Si《,3》N《,4》 and C《,3》N《,4》显示文摘 | Ouyang L Z and Ching W Y | 1999 | Physical Review Letters1999，83，： | 1 |
| 3 | Noniso- thermal crystallization and melting behavior of poly(β- hydroxybutyrate)-poly(vinyl-acetate) blends显示文摘 | An Y X Li L X Dong L S Mo Z S Feng Z L | 1999 | J Polym Sci Part B: Polym Phys1999，37，5： | 1 |
| 4 | Characterization of Aroma compounds in Chinese rice wine Qu by solvent-assisted flavor evaporation and headspace solid-phase microextrac- tion 显示文摘 | Mo X L Xu Y Fan W L | 2010 | Journal of Agricultural and Food Chemistry2010，58，： | 1 |
| 5 | Biochemical complementation of chalcone synthase mutants defines a role for flavonols in functional pollen显示文摘 | Mo Y Nagel C Taylor L P | 1992 | Proceedings of the National Academy of Sciences1992，89，15： | 1 |
| 6 | Zircon U-Pb dating and in-si- tu Hf isotopic analysis of Permian peraluminous granite in the Lha- sa terrane, southern Tibet: Implications for Permian collisional orogeny and paleogeography显示文摘 | Zhu D C Mo X X Niu Y L | 2009 | Tectonophysics2009，469，14： | 1 |
| 7 | 显示文摘 | Cai W L Mo C M | 1999 | Appl Phys Lett1999，74，20： | 1 |
| 8 | Theoretical prediction of the structure and properties of cubic spinel nitrides显示文摘 | Mo S D Ouyang L Z | 2002 | Journal of the American Ceramic Society2002，85，： | 1 |
| 9 | Undetstanding PRRSV Infection in Porcine Lung Based on Genome-Wide Transcriptome Response Identified by Deep Sequencing显示文摘 | Xiao S Q Jia J Y Mo D L | 2010 | PLoS ONE2010，5，6： | 1 |
| 10 | Shear retrofit of hollow bridge piers with carbon fiber-reinforced polymer sheets显示文摘 | Yeh Y K Mo Y L | 2005 | Journal of Composites for Construction2005，9，4： | 1 |
| 11 | Interesting physical properties of the new spinel phase of Si3 N4 and C3N4显示文摘 | MO S D OUYANG L CHING W Y | 1999 | Phys Rev Lett1999，83，24： | 1 |
| 12 | 查看详情显示文摘 | MO Y R BAO P GAO J L | | 0，，： | 1 |
| 13 | Study of grass carp (Ctenopharyngo~lon idellus )quality predictive model based on electronic nose 显示文摘 | Hui G Wang L Mo Y Zhang L | 2012 | Sensors and Actuators B: Chemical2012，35，2： | 1 |
| 14 | De Novo assembly of the Japanese flounder (Paralichthys olivaceus) spleen transcriptome to identify putative genes involved in immunity显示文摘 | Huang L Li G Y Mo Z L | 2015 | PLoS ONE2015，10，01： | 1 |
| 15 | Preparation and photoluminescence of alumina membranes with ordered pore arrays 显示文摘 | Su Y Cai W L Mo C M | 1999 | Appl Phys Lett1999，74，20： | 1 |
| 16 | Preparation and photo-luminescence of alumina membranes with ordered pore arrays 显示文摘 | DU Y CM W L MO C M | 1999 | A P L1999，74，20： | 1 |
| 17 | Torsional behavior of prestressed concrete box-girder bridges with corrugated steel webs 显示文摘 | Jeng Chyuan-Hwan Mo Y L Chang Y S | 2000 | ACI Structural Journal2000，97，6： | 1 |
| 18 | The in vivo and in vitro effects of chicken interferon on infectious bursal disease virus and New castle disease virus infection 显示文摘 | Mo C W Cao Y C Lim B L | 2001 | Avian Diseases2001，5，： | 1 |
| 19 | Full-scale tests on rectangular hollow bridge piers显示文摘 | Yeh Y K Mo Y L Yang C Y | 2002 | Materials and Structures2002，35，2： | 1 |
| 20 | Smart aggregate based damage detection of circular RC columns under cyclic combinedloading显示文摘 | Yashar Moslehy Haichang Gu Abdeldjelil Belarbi Y L Mo Gangbing Song | 2010 | Smart Materials and Structures2010，，6： | 1 |
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