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12篇 您的检索式:作者名="Mingjiang Xu"
    题名 作者 年代 出处 被引量
1Facile growth of homogeneous Ni(OH)2 coating on carbon nanosheets for high-performance asymmetric supercapacitor applications显示文摘Mingjiang Xie Zhicheng Xu Shuyi Duan Zhengfang Tian Yu Zhang Kun xiang Ming Lin Xuefeng Guo Weiping Ding 2018Nano Research2018,11,1:8
2Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine(5hmC)显示文摘As a dioxygenase, Ten-Eleven Translocation 2(TET2) catalyzes subsequent steps of 5-methylcytosine(5 mC) oxidation. TET2 plays a critical role in the self-renewal, proliferation,and differentiation of hematopoietic stem cells, but its impact on mature hematopoietic cells is not well-characterized. Here we show that Tet2 plays an essential role in osteoclastogenesis. Deletion of Tet2 impairs the differentiation of osteoclast precursor cells(macrophages) and their maturation into bone-resorbing osteoclasts in vitro. Furthermore, Tet2^(-/-) mice exhibit mild osteopetrosis, accompanied by decreased number of osteoclasts in vivo. Tet2 loss in macrophages results in the altered expression of a set of genes implicated in osteoclast differentiation, such as Cebpa, Mafb, and Nfkbiz. Tet2 deletion also leads to a genome-wide alteration in the level of 5-hydroxymethylcytosine(5 hmC) and altered expression of a specific subset of macrophage genes associated with osteoclast differentiation. Furthermore, Tet2 interacts with Runx1 and negatively modulates its transcriptional activity. Our studies demonstrate a novel molecular mechanism controlling osteoclast differentiation and function by Tet2, that is, through interactions with Runx1 and the maintenance of genomic 5 hmC. Targeting Tet2 and its pathway could be a potential therapeutic strategy for the prevention and treatment of abnormal bone mass caused by the deregulation of osteoclast activities.Yajing Chu Zhigang Zhao David Wayne Sant Ganqian Zhu Sarah M. Greenblatt Lin Liu Jinhuan Wang Zeng Cao Jeanette Cheng Tho Shi Chen Xiaochen Liu Peng Zhang Jaroslaw P. Maciejewski Stephen Nimer Gaofeng Wang Weiping Yuan Feng-Chun Yang Mingjiang Xu 2018Genomics, Proteomics & Bioinformatics2018,16,3:2
3Proteomic and molecular investigations revealed that Acidithiobacillus caldus adopts multiple strategies for adaptation to NaCl stress显示文摘Acidithiobacillus caldus plays an important role in commercial bioleaching.To understand how NaCl stress adaptation occurs in A.caldus,we grew A.caldus strain SM-1 in media containing high NaCl concentrations.SM-1 grew at concentrations of up to 1.0-mol L^(-1)NaCl,but growth was severely inhibited at higher concentrations.Proteomic analysis showed that SM-1 used multiple strategies to respond to NaCl stress.In addition to several heatshock proteins,enzymes involved in proline biosynthesis increased under NaCl stress.In addition,two DNA-binding proteins and a third protein of unknown function(Atc_(1291)),which was subsequently identified as a putative single-stranded DNA-binding protein,were up-regulated in the presence of NaCl stress.These DNA-binding proteins might play a role in response to osmotic stress.Atc_(1291)was cloned and expressed in Escherichia coli.Surprisingly,we found that E.coli BL21/pET28a-atc_(1291)grew to higher cell densities than E.coli BL21/pET28a,regardless of NaCI stress.Homologs to Atc_(1291)were identified in several groups of Proleohacleria.The role of Atc_(1291)in enhancing cell growth needs further investigation.Xu Guo Chengying Jiang Yuanming Luo Mingjiang Zhang Ansgar Poetsch Shuangjiang Liu 2014Chinese Science Bulletin2014,59,3:2
4Punicalagin Inhibits Inflammation in LPS-Induced RAW264.7 Macrophages via the Suppression of TLR4-Mediated MAPKs and NF-κB Activation显示文摘Xiaolong Xu Peng Yin Changrong Wan Xinlu Chong Mingjiang Liu Peng Cheng Jiajia Chen Fenghua Liu Jianqin Xu 2014Inflammation2014,,3:2
5Identify P2P traffic by inspecting data transfer behavior 显示文摘Xu Ke Zhang Ming Ye Mingjiang 2010Computer Communications2010,33,10:1
6Identify P2P traffic by inspecting data transfer behavior显示文摘Ke Xu Ming Zhang Mingjiang Ye Dah Ming Chiu Jianping Wu 2010Computer Communications2010,,10:1
7Identify P2P Traffic by Inspecting Data Trans- fer Behavior显示文摘XU Ke ZHANG Ming YE Mingjiang 2010Computer Communications2010,33,10:1
8Phase transition and photoluminescence properties of Eu^3+-doped ZnMoO4 red phosphors显示文摘Eu^(3+)-doped ZnMoO_4 with different doping concentrations were synthesized by a hydrothermal method. The effects of Eu^(3+)doping on the phase structure and photoluminescence(PL) properties of ZnMoO_4 were investigated. The result showed that the introduction of Eu^(3+) could lead to phase transition of ZnMoO_4. With the increase of Eu^(3+)doping amount, β-ZnMoO_4 was transformed to a phase gradually, which led to different photoluminescence performances. The optimized doping concentration of Eu^(3+) was 6 mol% for the highest emission intensity at 615 nm. Its CIE chromaticity coordinates were(0.667, 0.331), which were very close to the values of standard chromaticity(0.67, 0.33) for National Television Standards Committee(NTSC) system.Therefore, Eu^(3+)-doped ZnMoO_4 is considered to be a promising red-emitting phosphor for white LED applications.ZHOU Yu ZHANG ZhiJie CHU YaoQing PAN YunFang YOU MingJiang ZHENG TingTing XU JiaYue 2017Science China(Technological Sciences)2017,60,10:1
9Loca- tion of wire faults using chaotic signal 显示文摘Wang Anbang Zhang Mingjiang Xu Hang 2011IEEE Electron Device Letters2011,32,3:1
10Slope-assisted Raman distributed optical fiber sensing显示文摘Raman distributed optical fiber sensing is required to achieve accurate temperature measurements in a micro-scale area.In this study,we first analyze and demonstrate the pulse transmission feature in the temperature variation area and the superposition characteristics of Raman optical time-domain reflectometry(OTDR)signals by numerical simulation.The equations of superimposed Raman anti-Stokes scattered signals at different stages are presented,providing a theoretical basis for the positioning and physical quantity demodulation of whole optical fiber systems based on the OTDR principle.Moreover,we propose and experimentally demonstrate a slope-assisted sensing principle and scheme in a Raman distributed optical fiber system.To the best our knowledge,this is the first experimental demonstration of Raman distributed optical fiber sensing in a centimeter-level spatial measurement region.JIAN LI XINXIN ZHOU YANG XU LIJUN QIAO JIANZHONG ZHANG MINGJIANG ZHANG 2022Photonics Research2022,10,1:0
11Oxygen-vacancy-anchoring Ni_(x)O_(y) loading towards efficient hydrogen evolution via photo-thermal coupling reaction显示文摘Oxygen vacancy(Vo)is a significant component in defect engineering.The present work reports the anchoring effects of initial Vo for further loading modifications and the reducing capacity of photoinduced Vo for pure water splitting.Herein,we propose Ni-loaded Cu-doped TiO_(2)(NCT)materials by successive doping and loading.The continuously added Ni ions should accumulate around the Vos and gradually grow into complete nickel oxide crystals,achieving a higher average valence state of the Ni species.NiO crystals can be detected on a 0.5%NCT sample,while the structure of Ni_(2)O_(3) has been confirmed with a higher nickel mass ratio.Moreover,the introduction of nickel oxide effectively improves the photochemical and electrochemical performance by the interface charge separation,finally reaching an H2 yield of 30.6 pmol/g-cat on 0.5%NCT for Vo-based photo-thermal coupling reaction,which consists of Vo generation in photo and Vo consumption in thermal environment.In situ infrared spectroscopy further indicated that the presence of high valence state nickel oxide hindered the H2 formation but effectively promoted the conventional oxidizing reaction,with an H2 yield of 20.6 mmol/g-cat in a methanol-water reaction on the 2.0%NCT material.In summary,Vo controls the morphological structure of Ni loading and produces diverse effects for reactions with dissimilar mechanisms,which provides a novel way to design modifications for promoting various chemical reactions.Qiliang Wu Zheng Li Xuhan Zhang Chenyu Xu Mingjiang Ni Kefa Cen Yanwei Zhang 2021Journal of Energy Chemistry2021,30,10:0
12Investigation of distribution uniformity of distributor for biogas slurry application based on CFD analysis显示文摘A horizontal distributor for biogas slurry application was proposed to explore the distribution performance through CFD analysis and verified by field test.The rheological properties of biogas slurry were analyzed at first,and key parameters were obtained for the next simulation.The effects of distribution modes,inlet direction,and outlets number on the velocity distribution of flow field and mass flow rate of the horizonal distributor were investigated by CFD simulations.Results of rheological properties indicated that biogas slurry was a non-Newtonian fluid and exhibited shear-thinning behavior.It can be well described by power-law model.The simulation results showed that the geometry of rotor,especially the block numbers was the main factor that determining the fluid movement and trajectory of distribution and output.The mode rotor 1 with two blocks reached the lowest variable coefficient of mass flow rate(4.49%),indicating a higher degree of uniformity.The upward inlet direction would obtain less dead zone,and the distributor with an even outlets number would possess more uniform distribution and less dead zone.The field test of the distributor with rotor 1,upward inlet direction,and 24 outlets has been carried on to verify the simulation results,the variable coefficient of mass flow was 13.06%,which was slightly higher than the simulation(9.23%),but it still within the range of requirement(<15%).The proposed model and the findings of this work are of guiding significance for the study of the utilization technology and equipment of liquid biogas residue.Jingjing Fu Yongsheng Chen Binxing Xu Biao Ma Pengjun Wang Aibing Wu Mingjiang Chen 2023International Journal of Agricultural and Biological Engineering2023,16,1:0
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