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5篇 您的检索式:作者名="Michael Kann"
    题名 作者 年代 出处 被引量
1Intracellular transport of hepatitis B virus显示文摘For genome multiplication hepadnaviruses use the tran-scriptional machinery of the cell that is found within the nucleus.Thus the viral genome has to be transported through the cytoplasm and nuclear pore.The intracy-tosolic translocation is facilitated by the viral capsid that surrounds the genome and that interacts with cellular microtubules.The subsequent passage through the nu-clear pore complexes(NPC) is mediated by the nuclear transport receptors importin α and β.Importin α binds to the C-terminus of the capsid protein that comprises a nuclear localization signal(NLS).The exposure of the NLS is regulated and depends upon genome maturation and/or phosphorylation of the capsid protein.As for oth-er karyophilic cargos using this pathway importin α inter-acts with importin β that facilitates docking of the import complex to the NPC and the passage through the pore.Being a unique strategy,the import of the viral capsid is incomplete in that it becomes arrested inside the nuclear basket,which is a cage-like structure on the karyoplas-mic face of the NPC.Presumably only this compartment provides the factors that are required for capsid disas-sembly and genome release that is restricted to those capsids comprising a mature viral DNA genome.Michael Kann André Schmitz Birgit Rabe 2007World Journal of Gastroenterology2007,13,1:6
2Inhibition of host cell apoptosis by Eimeria bovis sporozoites显示文摘Mirjam Lang Michael Kann Horst Zahner 2009Veterinary Parasitology2009,160,:1
3Inhibition of host cell apoptosis by Eimeria bovis sporozoites显示文摘Mirjam Lang Michael Kann Horst Zahner 2009Veterinary Parasitology2009,160,:1
4Re-evaluation of anti-HBc non-reactive serum samples from patients with persistent hepatitis B infection by immune precipitation with labelled HBV core antigen显示文摘Vera C. Kantelhardt Alexandra Schwarz Ulrike Wend Christian G. Schüttler Wulf R. Willems Pascale Trimoulet Hervé Fleury Wolfram H. Gerlich Michael Kann 2009Journal of Clinical Virology2009,,2:1
5HBV多聚酶抗体对急性和慢性HBV感染者的诊断意义Michael Kann 刘正稳 1994国外医学情报1994,,17:0
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