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1篇 您的检索式:作者名="Mensavi Gbeassor"
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1In vitro antiplasmodial activity of crude extracts from Togolese medicinal plants显示文摘Objective:To investigate the antimalarial effect of a few plants in Togo folk medicine. Methods:After ethnobotanical survey,Opilia celtidifolia,Pavetta corymbosa(P.corymbosa) and Tamarindus indica(T.indica) were selected for screening.In vitro antimalarial tests were performed on crude extracts against fresh clinical isolates of Plasmodium falciparum using the semi microtest.Results:Different IC50,values of the extracts ranged from 2.042 to 100.000μg/mL. According to the results,the methanol extract of aerial part of P.corymbosa followed by aqueous extract of fruit of T.indica were the most active(IC50 of 2.042 and 4.786μg/mL,respectively). Qualitative test revealed the presence of alkaloids in the leaves of P.corymbosa that may be responsible for the activity of the plant.Conclusions:Our study provides scientific evidence for usage of plant in the folk medicine,and further studies are needed for identification and purification of the active principles.Koffi Koudouvo Simplice D.Karou Denise P.Ilboudo Kouami Kokou Kodjo Essien Kodjo Aklikokou Comlan de Souza Jacques Simpore Mensavi Gbeassor 2011Asian Pacific Journal of Tropical Medicine2011,4,2:1
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