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| 1 | Recent advances in the synthesis of 1,1-diarylalkanes by transitionmetal catalysis显示文摘1,1-Diaryl moieties are core structures in a wide range of bioactive and pharmaceutical compounds.Transition-metal catalysis is a convenient approach to accessing these invaluable compounds affording high yields and enantioselectivities.This review summarizes 1,1-diarylalkanes synthesis through transition metal catalysis.Particular focus is given to recent developments,such as reductive cross-electrophile couplings,benzylic C–H bond arylation,transformations involving metal migration,asymmetric hydrogenation of 1,1-diarylalkenes and three-component coupling reactions. | Md.Belal Zheqi Li Xiuqiang Lu Guoyin Yin | 2021 | Science China Chemistry2021，64，4： | 1 |
| 2 | 镍/铜协同催化的末端烯烃的迁移芳硅化反应显示文摘有机硅化物的广泛应用,引起了人们对有机硅的合成的广泛研究,其中用烯烃合成有机硅烷是一个非常重要的研究方向.本文发展了一个镍/铜双金属催化的末端烯烃的迁移选择性芳硅化反应,一步反应同时向烯烃引入芳基和硅基两个基团.通过此方法,可以从末端烯烃、芳基卤化物和Suginome试剂制备多种烷基取代的硅烷.该反应具有良好的区域选择性、温和的反应条件和良好的官能团兼容性的优点.除苄位外,也可以在烯丙位构建碳-碳键.初步的机理研究表明,铜助催化剂促进了Suginome试剂向镍的转金属,吡啶噁唑啉配体的存在可抑制烯烃插入芳基镍物种产生的副产物.此外,对吡啶噁唑啉类配体的研究表明,噁唑啉部分的位阻对链行走过程有极大的影响,但不对后续的芳基化造成影响. | 赵斌治 李玉强 李浩阳 Md.Belal 朱磊 阴国印 | 2021 | Science Bulletin2021，66，6： | 1 |
| 3 | Catalyst-controlled regiodivergent 1,2-difunctionalization of alkenes with two carbon-based electrophiles显示文摘Regiodivergent catalysis provides an efficient strategic approach for the construction of architecturally different molecules from the same starting materials. In this field, the intermolecular regiodivergent 1,2-difunctionalization of alkenes with two electrophiles is still a challenging task. A ligand-controlled, nickel-catalyzed regiodivergent dicarbofunctionalization of alkenes using both aryl/vinyl halides and acetals as electrophiles under mild reductive reaction conditions has been accomplished. This study provides a general approach to accessing both β-methoxyl esters and γ-methoxyl esters from readily available acrylates,aryl halides and acetals. Experimental mechanistic evidence supports that the difference in regioselective outcomes is attributed to the ligand tuning the reactivity of the nickel catalyst, which results in different catalytic cycles operating for these two reaction conditions. | Md.Belal Zheqi Li Lei Zhu Guoyin Yin | 2022 | Science China Chemistry2022，65，3： | 0 |
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