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| 1 | 广东五种菊头蝠的核型分析显示文摘本文用蝙蝠的新鲜肺组织和尾椎进行组织培养,然后在光学显微镜下计数30个染色体分散良好的中期分裂相细胞,并进行摄影、剪贴和测量。分析了广东地区5种菊头蝠的核型,即小菊头蝠的核型为2n =6 2 ,FN =6 0 ;角菊头蝠的核型为2n =6 2 ,FN =6 0 ;中菊头蝠的核型为2n =6 2 ,FN =6 0 ;大耳菊头蝠的核型为2n =6 2 ,FN =6 0 ;中华(栗黄)菊头蝠的核型为2n =36 ,FN =6 0。大耳菊头蝠的核型为首次报道。角菊头蝠和中菊头蝠的核型与前人报道的结果基本相同。中华(栗黄)菊头蝠的核型(2n =36 )与张维道报道的鲁氏菊头蝠相同,而与印度和斯里兰卡产R rouxii的核型2n =5 6迥异。 | 吴毅 Masashi HARADA | 2005 | 兽类学报2005，25，2： | 11 |
| 2 | 超低频地磁异常与2000年日本伊豆诸岛震群的关系显示文摘通过研究电磁现象与大地震的联系有助于建立监测地壳运动(如地震、火山喷发)的电磁方法.在地震的紧急预报中,超低频(ULF)地磁的方法是最有前途的方法之一.本文将一种主要分量分析的新方法应用在了与2000年日本伊豆诸岛震群有关的ULF地磁资料的研究中.这次震群活动始于2000年6月26日,同年9月结束.在这次地震活动中,观测到5次震级超过6级的大地震(分别发生在7月1日、8日、15日、30日和8月18日).在此期间,我们的超低频地磁观测站幸运地记录下了数据,其中有三个观测站相距很近(大约5 km的距离),距地震中心大约80~100 km.因为我们可以在正交分解的基础上,用主要分量分析法将一些噪声分辨出来,所以我们把主要分量分析法用在了超低频地磁水平方向的NS分量中.我们研究了主要分量分析法结果中本征值和本征矢量的临时变化,这些结果总结如下.第一主要分量是源于日地交互作用影响的信号,如:地磁脉动.第一主要分量的本征矢量的变化说明这种信号在整个分析过程中非常稳定.第二主要分量中混有当地的人为的噪音.而最小的第三分量出现在伊豆半岛当地的子夜,在大地震前几天,第三本征值明显地增加.大约在震群活动开始前三个月,第三本征值的水平有微小增强.相应地,在信号的子空间中本征矢量方向的模式同时改变,在震群活动后又恢复到了其原来的水平.这些特征可能与大地震有关.最后我们强调主要分量分析的方法是目前监测地壳活动最有前途的方法. | Katsumi Hattori Aya Serita Kaoru Gotoh Chie Yoshino Makoto Harada Nobuhiro Isezaki Masashi Hayakawa 辛长江 | 2005 | 国际地震动态2005，，11： | 4 |
| 3 | New combination test for hepatitis C virus genotype and viral load determination using Amplicor GT HCV MONITOR test v2.0显示文摘AIM: To develop a new sensitive and inexpensive hepatitis C virus (HCV) combination test (HCV Guideline test) that enables the determination of HCV genotypes 1, 2 and 3,and simultaneous determination of HCV viral load using commercial Amplicor GT HCV MONITOR test v2.0 (microwell version).METHODS: The HCV Guideline test used the PCR product generated in commercial Amplicor GT HCV Monitor test v2.0 for viral load measurement using microwell plate version of Amplicor HCV Monitor and also captured on separate plates containing capture probes and competitive oligonucleotide probes specific for HCV genotypes 1, 2 and 3, The HCV genotype was subsequently determined using the biotin-labeled PCR product and five biotin-labeled HCV-specific probes.RESULTS: The sensitivity of the HCV Guideline test was 0.5 KIU/mL. Specificity of the HCV Guideline test was confirmed by direct sequencing of HCV core region and molecular evolutionary analyses based on a panel of 31 samples. The comparison of the HCV Guideline test and an in-house HCV core genotyping assay using 252 samples from chronic hepatitis C patients indicated concordant results for 97.2% of samples (59.5% genotype 1, 33.7% genotype 2, 6.0% genotype 3, and 0.8% mixed genotypes).Similarly, the HCV Guideline test showed concordance with a serological test, and the serological test failed to assign any serotype in 12.7% of the samples, indicating a better sensitivity of the HCV Guideline test.CONCLUSION: Clinically, both viral load and genotypes (1, 2 and 3) have been found to be major predictors of antiviral therapy outcome regarding chronic hepatitis C based on guidelines and they are, in normal circumstances,performed as separate stand-alone assays. The HCV Guideline test is a useful method for screening large cohorts in a routine clinical setting for determining the treatment regimen and for predicting the outcome of antiviral therapy of chronic hepatitis C. | Motokazu Mukaide Yasuhito Tanaka Hirokazu Kakuda Kei Fujiwara Fuat Kurbanov Eturo Orito Kentaro Yoshioka Kiyotaka Fujise Shoji Harada Takazumi Kozaki Kazuo Takemura Kazumasa Hikiji Masashi Mizokami | 2005 | World Journal of Gastroenterology2005，11，4： | 3 |
| 4 | Serum Folate and Homocysteine Levels Are Associated With Colon Tumorigenesis in End-Stage Renal Disease Patients显示文摘 | Eisuke Kaji Jun Kato Shunsuke Saito Keita Harada Kenji Kuwaki Masashi Tatsukawa Tamiya Morikawa Sakiko Hiraoka Hiroshi Matsushima Kazuhide Yamamoto | 2011 | Nutrition and Cancer2011，，2： | 1 |
| 5 | Analysis of dose–volume histogram parameters for radiation pneumonitis after definitive concurrent chemoradiotherapy for esophageal cancer显示文摘 | Hirofumi Asakura Takayuki Hashimoto Sadamoto Zenda Hideyuki Harada Koichi Hirakawa Masashi Mizumoto Kazuhisa Furutani Shuichi Hironaka Hiroshi Fuji Shigeyuki Murayama Narikazu Boku Tetsuo Nishimura | 2010 | Radiotherapy and Oncology2010，，2： | 1 |
| 6 | Influence of soil properties on the biodegradation of 1,3,6,8-tetrachlorodibenzop-dioxin and fungal treatment of contaminated paddy soil by white rot fungus Phlebia brevispora显示文摘 | Ichiro Kamei Masashi Watanabe Kazuhisa Harada | 2009 | Chemosphere2009，75，： | 1 |
| 7 | Analysis of dose–volume histogram parameters for radiation pneumonitis after definitive concurrent chemoradiotherapy for esophageal cancer显示文摘 | Hirofumi Asakura Takayuki Hashimoto Sadamoto Zenda Hideyuki Harada Koichi Hirakawa Masashi Mizumoto Kazuhisa Furutani Shuichi Hironaka Hiroshi Fuji Shigeyuki Murayama Narikazu Boku Tetsuo Nishimura | 2010 | Radiotherapy and Oncology2010，，2： | 1 |
| 8 | Effect of magnesium sulfate pretreatment and dignifieanee of matrix metalloproteinase - 1 and interleukin - 6 levels in coronary reperfusion therapy for patients with acute myocardial infarction 显示文摘 | Masashi Shibata Kenji Ueshima Masako Harada | 1999 | Angiology1999，50，： | 1 |
| 9 | Effect of magnesium sulfa te pretreatment and significance of matrix metal-proteinase-1 and interleukin-6 levels in coronary reperfusion therapy for patients with acute myocardial infar ction显示文摘 | Masashi Shibata Kenji Ueshima Masako Harada | 1999 | Angiology1999，50，： | 1 |
| 10 | Theoretical analysis of a new design concept for LTA structure显示文摘 | Masashi HARADA Masa-aki SANO | 2002 | AIAA2002，3425，： | 1 |
| 11 | Acoustic Radiation Force Impulse Imaging of the Pancreas for Estimation of Pathologic Fibrosis and Risk of Postoperative Pancreatic Fistula显示文摘 | Nobuhiro Harada Takeaki Ishizawa Yosuke Inoue Taku Aoki Yoshihiro Sakamoto Kiyoshi Hasegawa Yasuhiko Sugawara Mariko Tanaka Masashi Fukayama Norihiro Kokudo | 2014 | Journal of the American College of Surgeons2014，，5： | 1 |
| 12 | Advantages of the rapid double-staining method for intraoperative detectionof micrometastasis in sentinel lymph nodes显示文摘 | Toshihiko Ojima Shinichi Kinami Keishi Nakamura Katsunobu Oyama Masashi Inokuchi Hideto Fujita Itasu Ninomiya Sachio Fushida Takashi Fujimura Seiko Kitamura Shinichi Harada Tetsuo Ohta | 2013 | Oncology Reports2013，，3： | 1 |
| 13 | Karyotypes of field mice of the genus Apodemus (Mammalia: Rodentia) from China显示文摘Karyotypes of four Chinese species of field mice of the genus Apodemus were examined, including Apodemus chevrieri(diploid chromosome number,2 n=48, fundamental number of autosomal arms,FNa=56), A. draco(2 n=48, FNa=48), A. ilex(2 n=48, FNa=48), and A. latronum(2 n=48, FNa=48).Karyotypes of A. chevrieri, A. draco, and A. ilex are reported here for the first time, providing useful information for their species taxonomy. Determining the karyotypes of all species of Apodemus in Asia,both in this and previous studies, provides a solid overview of the chromosome evolution and species differentiation of the genus in East Asia. In addition to allopatric speciation, chromosome rearrangements likely played an important role in the formation of the four Apodemus species groups as well as speciation within each group in East Asia. For example, increased centromeric heterochromatin in A. latronum may have contributed to the post-mating reproductive isolation from the A. draco-A. ilex-A. semotus clade. | Masaharu Motokawa Yi Wu Masashi Harada Yuta Shintaku Xue-Long Jiang Yu-Chun Li | 2018 | Zoological Research2018，39，5： | 1 |
| 14 | Effect of exercise-induced acidosis on aldosterone secretion in men显示文摘 | Takeshi Yamauchi Takeshi Harada Masashi Kurono Nobuo Matsui | 1998 | European Journal of Applied Physiology and Occupational Physiology1998，，5： | 1 |
| 15 | Rho-kinase inhibitors decrease TGF-β-stimulated VEGF synthesis through stress-activated protein kinase/c- Jun N-terminal kinase in osteoblasts显示文摘 | Masashi Kuno Shinji Takai Rie Matsushima-Nishiwaki Chiho Minamitani Jun Mizutani Takanobu Otsuka Atsushi Harada Seiji Adachi Osamu Kozawa Haruhiko Tokuda | 2008 | Biochemical Pharmacology2008，，2： | 1 |
| 16 | Cyclic Stretch Augments Production of Neutrophil Chemokines and Matrix Metalloproteinase‐1 in Human Uterine Smooth Muscle Cells显示文摘 | Yin Zhao Kaori Koga Yutaka Osuga Gentaro Izumi Masashi Takamura Miyuki Harada Tetsuya Hirata Yasushi Hirota Osamu Yoshino Tomoyuki Fujii Shiro Kozuma | 2012 | Am J Reprod Immunol2012，，： | 1 |
| 17 | Surgical outcomes in the newly introduced phase of intracorporeal anastomosis following laparoscopic distal gastrectomy is safe and feasible compared with established procedures of extracorporeal anastomosis显示文摘 | Shingo Kanaji Hitoshi Harada Shunji Nakayama Takashi Yasuda Taro Oshikiri Kentaro Kawasaki Masashi Yamamoto Tatsuya Imanishi Tetsu Nakamura Satoshi Suzuki Kenichi Tanaka Yasuhiro Fujino Masahiro Tominaga Yoshihiro Kakeji | 2014 | Surgical Endoscopy2014，，4： | 1 |
| 18 | The status of the Japanese and East Asian bats of the genus Myotis (Veapertilionidae) based on mitochondrial sequences显示文摘 | Kuniko Kawai Masato Nikaido Masashi Harada | 2003 | Molecular Phylogenetics and Evolution2003，28，： | 1 |
| 19 | Effect of magnesium sulfate pretreatment and dignificance of matrix metalloproteinase-1 and interleukin-6 levels in coronary reperfusion therapy for patients with acute myocardial infaretion显示文摘 | Masashi Shibata Kenji Ueshima Masako Harada | 1999 | Angiology1999，50，： | 1 |
| 20 | Karyotypes of three shrew species(Soriculus nigrescens,Episoriculus caudatus and Episoriculus sacratus)from Nepal显示文摘The karyotypes of three shrew species(Mammalia,Soricomorpha,Soricidae)from Nepal were examined for the first time.Based on the karyotypes and overall differences in skull size,the current Episoriculus caudatus appeared to include two distinct species:the larger E.caudatus and the smaller Episoriculus sacratus.Episoriculus sacratus has three subspecies,E.s.soluensis in Nepal and Sikkim,E.s.umbrinus in Assam,Myanmar and the Yunnan Province of China,and E.s.sacratus in the Sichuan Province of China.Soriculus nigrescens had a diploid chromosome number(2n)and fundamental number(FN),including two X chromosomes,of 64 and 92,respectively,consisting of 11 metacentric or submetacentric,two subtelocentric and 18 acrocentric pairs of autosomes,a metacentric X and an acrocentric Y chromosome.Episoriculus sacratus soluensis had 2n=74 and FN=126,consisting of 12 metacentric or submetacentric,13 subtelocentric and 11 acrocentric pairs of autosomes,a submetacentric X and an acrocentric Y chromosome.Episoriculus caudatus had 2n=60 and FN=118,consisting of 19 metacentric or submetacentric,nine subtelocentric and one acrocentric pair of autosomes,a subtelocentric X and an acrocentric Y chromosome.The karyotypes of these three species are characterized by their large 2n and FN values compared with other Soricidae. | Masaharu MOTOKAWA Masashi HARADA Kazuyuki MEKADA Krishna C.SHRESTHA | 2008 | Integrative Zoology2008，3，3： | 0 |
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