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1篇 您的检索式:作者名="Marla Weetall"
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1Targeting BMI1 mitigates chemoresistance in ovarian cancer显示文摘Resistance to chemotherapy is a prominent clinical problem in high grade serous ovarian cancer(HGSOC).1 An inadequate understanding of adaptive signaling coupled with limited treatment options for a chemoresistant tumor are likely causes for poor outcomes.We previously reported that BMI1,a stem-cell factor is instrumental in regulating chemoresistance.2,3 However,to advance anti-BMI1 therapy from the bench to the bedside,efficacy needs to be tested in patient-derived chemoresistant HGSOC models,which is lacking.Anindya Dey Shailendra Kumar Dhar Dwivedi Lin Wang Md Nazir Hossen Fiifi Neizer-Ashun Magdalena Bieniasz Priyabrata Mukherjee John DBaird Marla Weetall Resham Bhattacharya 2022Genes & Diseases2022,9,6:0
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