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| 1 | 卒中相关性肺炎的诊断卒中肺炎共识小组的推荐意见显示文摘背景和目的下呼吸道感染常并发于卒中并对转归造成不利影响。对于并发于卒中的下呼吸道感染性疾病,目前尚无公认的专业术语或诊断金标准,这导致临床诊疗和研究受到影响。本共识旨在提出急性卒中并发下呼吸道感染的标准化术语和可操作性诊断标准。方法对多个文献数据库进行系统检索,经过证据回顾和2轮讨论,最后于2014年9月在英国曼彻斯特召开共识会议,经75%以上共识小组成员达成一致意见后形成共识。结果达成的共识如下:(1)推荐使用卒中相关性肺炎(stroke-associated pneumonia, SAP )作为卒中发病后7 d内发生的下呼吸道感染性疾病的专业术语。(2)提议对 SAP 使用经过改良的美国疾病控制预防中心(Centers for Disease Control and Prevention, CDC)诊断标准:①很可能的 SAP:符合 CDC 诊断标准,但复查或动态监测胸部 X 片仍缺乏典型改变;②确诊的 SAP:符合 CDC 诊断标准,且胸部 X 片有典型改变。(3)关于白细胞计数或 C反应蛋白在 SAP 诊断中的作用证据有限。(4)其他生物学标记物(如降钙素原)的证据不足。结论提议根据 CDC 诊断标准对 SAP 的术语和诊断制定可操作性的共识标准,需要在卒中患者中进行前瞻性研究来确定其信度、效度以及对医生行为(包括抗生素选择)和临床转归的影响。 | Craig J. Smith Amit K Kishore Andy Vail Angel Chamorro Javier Garau Stephen J. Hopkins Mario Di Napoli Lalit Kalra Peter Langhorne Joan Montaner Christine Roffe Anthony G. Rudd Pippa J. TyrreU Diederik van de Peek Mark Woodhead Andreas Meisel 范琳琳 宿英英 | 2016 | 国际脑血管病杂志2016,24,2: | 17 |
| 2 | Steps to consider in the approach and management of critically ill patient with spontaneous intracerebral hemorrhage显示文摘Spontaneous intracerebral hemorrhage is a type of stroke associated with poor outcomes. Mortality is elevated, especially in the acute phase. From a pathophysiological point of view the bleeding must traverse different stages dominated by the possibility of re-bleeding, edema, intracranial hypertension, inflammation and neurotoxicity due to blood degradation products, mainly hemoglobin and thrombin. Neurological deterioration and death are common in early hours, so it is a true neurologicalneurosurgical emergency. Time is brain so that action should be taken fast and accurately. The most significant prognostic factors are level of consciousness, location, volume and ventricular extension of the bleeding. Nihilism and early withdrawal of active therapy undoubtedly influence the final result. Although there are no proven therapeutic measures, treatment should be individualized and guided preferably by pathophysiology. The multidisciplinary teamwork is essential. Results of recently completed studies have birth to promising new strategies. For correct management it's important to establish an orderly and systematic strategy based on clinical stabilization, evaluation and establishment of prognosis, avoiding secondary insults and adoption of specific individualized therapies, including hemostatic therapy and intensive control of elevated blood pressure. Uncertainty continues regarding the role of surgery. | Daniel Agustin Godoy Gustavo Rene Pi?ero Patricia Koller Luca Masotti Mario Di Napoli | 2015 | World Journal of Critical Care Medicine2015,4,3: | 14 |
| 3 | Accuracy and Clinical Usefulness of Intracerebral Hemorrhage Grading Scores: A Direct Comparison in a UK Population显示文摘 | Adrian R. Parry-Jones Kamran A. Abid Mario Di Napoli Craig J. Smith Andy Vail Hiren C. Patel Andrew T. King Pippa J. Tyrrell | 2013 | Stroke2013,,7: | 2 |
| 4 | C-Reactive Protein in Ischemic Stroke: An Independent Prognostic Factor显示文摘 | Mario Di Napoli Francesca Papa Vittorio Bocola | 2001 | Stroke: Journal of the American Heart Association2001,,4: | 2 |
| 5 | Evaluation of C-Reactive Protein Measurement for Assessing the Risk and Prognosis in Ischemic Stroke: A Statement for Health Care Professionals From the CRP Pooling Project Members显示文摘 | Mario Di Napoli Markus Schwaninger Roberto Cappelli Elena Ceccarelli Giacinto Di Gianfilippo Cristina Donati Hedley C.A. Emsley Sandro Forconi Stephen J. Hopkins Luca Masotti Keith W. Muir Anna Paciucci Francesca Papa Sabina Roncacci Dirk Sander Kerstin S | 2005 | Stroke2005,,6: | 2 |
| 6 | Is Plasma Fibrinogen Useful in Evaluating Ischemic Stroke Patients?: Why, How, and When显示文摘 | Mario Di Napoli Puneetpal Singh | 2009 | Stroke2009,,5: | 1 |
| 7 | Statin Therapy and Outcome After Ischemic Stroke: Systematic Review and Meta-Analysis of Observational Studies and Randomized Trials显示文摘 | Danielle Ní Chróinín Kjell Asplund Signild ?sberg Elizabeth Callaly Elisa Cuadrado-Godia Exuperio Díez-Tejedor Mario Di Napoli Stefan T. Engelter Karen L. Furie Sotirios Giannopoulos Antonio M. Gotto Niamh Hannon Fredrik Jonsson Moira K. Kapral Joan Martí | 2013 | Stroke2013,,2: | 1 |
| 8 | Clinical Use of C-Reactive Protein for Prognostic Stratification in Ischemic Stroke: Has the Time Come for Including It in the Patient Risk Profile?显示文摘 | Mario Di Napoli Francesca Papa | 2003 | Stroke: Journal of the American Heart Association2003,,2: | 1 |
| 9 | C-Reactive Protein in Ischemic Stroke: An Independent Prognostic Factor显示文摘 | Mario Di Napoli Francesca Papa Vittorio Bocola | 2001 | Stroke: Journal of the American Heart Association2001,,4: | 1 |
| 10 | Prognostic Influence of Increased C-Reactive Protein and Fibrinogen Levels in Ischemic Stroke显示文摘 | Mario Di Napoli Francesca Papa Vittorio Bocola | 2001 | Stroke: Journal of the American Heart Association2001,,1: | 1 |
| 11 | Statin Therapy and Outcome After Ischemic Stroke: Systematic Review and Meta-Analysis of Observational Studies and Randomized Trials显示文摘 | Danielle Ní Chróinín Kjell Asplund Signild ?sberg Elizabeth Callaly Elisa Cuadrado-Godia Exuperio Díez-Tejedor Mario Di Napoli Stefan T. Engelter Karen L. Furie Sotirios Giannopoulos Antonio M. Gotto Niamh Hannon Fredrik Jonsson Moira K. Kapral Joan Martí | 2013 | Stroke2013,,2: | 1 |
| 12 | Hyperglycemia and Short-term Outcome in Patients with Spontaneous Intracerebral Hemorrhage显示文摘 | Daniel A. Godoy Gustavo R. Pi?ero Silvana Svampa Francesca Papa Mario Di Napoli | 2008 | Neurocritical Care2008,,2: | 1 |
| 13 | Angiotensin-Converting Enzyme Inhibitor Use Is Associated With Reduced Plasma Concentration of C-Reactive Protein in Patients With First-Ever Ischemic Stroke显示文摘 | Mario Di Napoli Francesca Papa | 2003 | Stroke2003,34,: | 1 |
| 14 | Ubiquitin-Proteasome System and Proteasome Inhibition: New Strategies in Stroke Therapy显示文摘 | Cezary Wojcik Mario Di Napoli | 2004 | Stroke: Journal of the American Heart Association2004,,6: | 1 |
| 15 | C - reactive protein in ischemic 显示文摘 | Mario Di Napoli Francesca Papa | 2002 | stroke2002,33,9: | 1 |
| 16 | C-Reactive Protein Level Measurement Improves Mortality Prediction When Added to the Spontaneous Intracerebral Hemorrhage Score显示文摘 | Mario Di Napoli Daniel Agustin Godoy Veronica Campi Marta del Valle Gustavo Pi?ero Matias Mirofsky Aurel Popa-Wagner Luca Masotti Francesca Papa Alejandro A. Rabinstein | 2011 | Stroke A Journal of Cerebral Circulation2011,,5: | 1 |
| 17 | C-Reactive Protein and Outcome After First-Ever Ischemic Stroke显示文摘 | Mario Di Napoli Giacinto Di Gianfilippo Annamaria Sollecito Vittorio Bocola | 2000 | Stroke: Journal of the American Heart Association2000,,1: | 1 |
| 18 | C-Reactive Protein in Ischemic Stroke: An Independent Prognostic Factor 显示文摘 | Mario Di Napoli Francesca Papa Vittorio Bocola | 2001 | Stroke2001,32,: | 1 |
| 19 | High Stroke Incidence in the Prospective Community-Based L’Aquila Registry (1994-1998): First Year’s Results显示文摘 | Antonio Carolei Carmine Marini Mario Di Napoli Giacinto Di Gianfilippo Paola Santalucia Massimo Baldassarre Giorgio De Matteis Ferdinando di Orio | 1997 | Stroke: A Journal of Cerebral Circulation1997,,12: | 1 |
| 20 | C反应蛋白与急性缺血性卒中显示文摘 | Mario Di Napoli 赵元攸 | 2002 | 英国医学杂志中文版2002,5,3: | 0 |