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| 1 | 世界胃肠病学组织全球指南——发展中国家幽门螺杆菌感染显示文摘世界上有一半人口感染幽门螺杆菌(H.pylori),其感染率因地理位置、种族、年龄和社会经济状况不同而存在很大差异.在发展中国家较高.发达国家较低。但总体而言,近年世界许多地区的H.pylori感染率均呈下降趋势。 | Hunt RH Xiao SD Megraud F Leon-Barua R Bazzoli F van der Merwe S Vaz Coelho LG Fock M Fedail S Cohen H Malfertheiner P Vakil N Hamid S Goh KL Wong BCY Krabshuis J Le Mair A 杜颖 戴宁 | 2011 | 胃肠病学2011，16，7： | 27 |
| 2 | 在血压控制不良的高血压患者中使用数字化干预的家庭和在线血压管理:随机对照试验显示文摘HOME BP试验(The home and online management and evaluation of blood pressure)的目的是评估在初级预防中结合自我监测和自我管理的数字化干预在高血压管理中的作用。研究者纳入英国76个治疗中心经过治疗但血压控制不好(>140/90 mm Hg, 1 mm Hg=0.133 kPa)并能上网的患者622例,进行自动确定主要终点的公开随机对照试验。 | McMa-nus RJ Little P Stuart B Morton K Raftery J Kelly J Bradbury K Zhang J Zhu S Murray E May CR Mair FS Michie S Smith P Band R Ogburn E AllenJ Rice C Nut-tall J Williams B Yardley L 陈嘉睿(译) 叶鹏(审校) | 2021 | 中华高血压杂志2021，29，5： | 15 |
| 3 | Retrospective study on mixed neuroendocrine non-neuroendocrine neoplasms from five European centres显示文摘BACKGROUND Mixed neuroendocrine non-neuroendocrine neoplasm(MiNEN)is a rare diagnosis,mainly encountered in the gastro-entero-pancreatic tract.There is limited knowledge of its epidemiology,prognosis and biology,and the best management for affected patients is still to be defined.AIM To investigate clinical-pathological characteristics,treatment modalities and survival outcomes of a retrospective cohort of patients with a diagnosis of MiNEN.METHODS Consecutive patients with a histologically proven diagnosis of MiNEN were identified at 5 European centres.Patient data were retrospectively collected from medical records.Pathological samples were reviewed to ascertain compliance with the 2017 World Health Organisation definition of MiNEN.Tumour responses to systemic treatment were assessed according to the Response Evaluation Criteria in Solid Tumours 1.1.Kaplan-Meier analysis was applied to estimate survival outcomes.Associations between clinical-pathological characteristics and survival outcomes were explored using Log-rank test for equality of survivors functions(univariate)and Cox-regression analysis(multivariable).RESULTS Sixty-nine consecutive patients identified;Median age at diagnosis:64 years.Males:63.8%.Localised disease(curable):53.6%.Commonest sites of origin:colon-rectum(43.5%)and oesophagus/oesophagogastric junction(15.9%).The neuroendocrine component was;predominant in 58.6%,poorly differentiated in 86.3%,and large cell in 81.25%,of cases analysed.Most distant metastases analysed(73.4%)were occupied only by a poorly differentiated neuroendocrine component.Ninety-four percent of patients with localised disease underwent curative surgery;53%also received perioperative treatment,most often in line with protocols for adenocarcinomas from the same sites of origin.Chemotherapy was offered to most patients(68.1%)with advanced disease,and followed protocols for pure neuroendocrine carcinomas or adenocarcinomas in equal proportion.In localised cases,median recurrence free survival(RFS);14.0 months(95%CI:9.2-24.4),and median overall survival(OS):28.6 months(95%CI:18.3-41.1).On univariate analysis,receipt of perioperative treatment(vs surgery alone)did not improve RFS(P=0.375),or OS(P=0.240).In advanced cases,median progression free survival(PFS);5.6 months(95%CI:4.4-7.4),and median OS;9.0 months(95%CI:5.2-13.4).On univariate analysis,receipt of palliative active treatment(vs best supportive care)prolonged PFS and OS(both,P<0.001).CONCLUSION MiNEN is most commonly driven by a poorly differentiated neuroendocrine component,and has poor prognosis.Advances in its biological understanding are needed to identify effective treatments and improve patient outcomes. | Melissa Frizziero Xin Wang Bipasha Chakrabarty Alexa Childs Tu V Luong Thomas Walter Mohid S Khan Meleri Morgan Adam Christian Mona Elshafie Tahir Shah Annamaria Minicozzi Wasat Mansoor Tim Meyer Angela Lamarca Richard A Hubner Juan W Valle Mairéad G McNamara | 2019 | World Journal of Gastroenterology2019，25，39： | 13 |
| 4 | 肿瘤体积、厚度和T分类作为手术治疗舌鳞状细胞癌效果的预测因子显示文摘背景:根据TNM分类,在同一分类中具有良好预后的浅表肿瘤与深度浸润、预后不好的肿瘤常被混淆。方法:对588例未接受过治疗的舌癌患者进行回顾研究。使用肿瘤体积和厚度作为单独的模型,二元逻辑回归用于确定淋巴结转移和包膜外扩散(ECS)的预测价值。生成C指数以量化T分类、厚度和存活的肿瘤体积的预测准确性。 | Mair M Nair D Nair S 赵泽亮 | 2018 | 中国口腔颌面外科杂志2018，16，5： | 7 |
| 5 | Future biomarkers for detection of ischemia and risk stratification in acute coronary syndrome 显示文摘 | Apple F S Wu A H Mair J | 2005 | Clin Chem2005，51，： | 1 |
| 6 | Growth performance trials of genetically male tilapia (GMT) derived from YY-male in Oreochromis niloticus L: on station comparisons with mixed sex and sex reversed male populations 显示文摘 | Mair G C Abucay J S Beardmore J A | 1995 | Aquaculture1995，137，： | 1 |
| 7 | ~chanics of tunnelling machine screw conveyors : A theoretical model 显示文摘 | A S Merritt R J Mair | 2008 | Geotechnique2008，58，2： | 1 |
| 8 | Future biomarkers for detection of ischemia and risk stratification in acute coronary syndrome 显示文摘 | Apple S Wu H Johannes Mair | 2005 | Clin Chem2005，51，： | 1 |
| 9 | Acoustic impedanceinversion and seismic reflection continuity analysis for delineating gas hydrate near the Mallik research sites, Mackenzie Delta, northwest Territories, Canada 显示文摘 | Riedel M Bellefleur G Mair S | 2009 | Geophysics2009，74，5： | 1 |
| 10 | Selective modification of alternative splicing by indole derivatives that target serine-arginine-rich protein splicing factors显示文摘 | Soret J Bakkour N Maire S | 2005 | Proc Natl Acad Sci USA2005，102，24： | 1 |
| 11 | Effects of sparfloxa- cin, grepafloxacin, moxi-floxacin, and ciprofloxacin on cardiac action potential duration显示文摘 | Patmore L Fraser S Mair D | 2000 | Eur J Pharmacol2000，406，3： | 1 |
| 12 | Exhaled nitric oxide in relation to the clinical features of childhood asthma显示文摘 | Timothy J Vivienne Mairs Patrick S etal | 2004 | J Asthma2004，41，7： | 1 |
| 13 | Serum urate as an independent predictor of poor outcome and future vascular events after acute stroke显示文摘 | Weir C J Mair S W Waters M R | 2003 | Stroke2003，34，8： | 1 |
| 14 | Oxygen evolution loss and structural transitions in photosystem II induced by low intensity UV-B radiation of 280 nm wavelength显示文摘 | Ségui J A Maire V Gabashvili I S | 2000 | Journal of Photochemistry and Photobiology B: Biology2000，56，： | 1 |
| 15 | Relationship between natriuretic peptides and hemodynamics in patients with heart failure at rest and after ergometric exercise显示文摘 | Friedl W Mair J Thomas S | 1999 | Clin Chim Acta1999，281，12： | 1 |
| 16 | Effects of sparfloxacin,grepafloxacin,moxifloxacin,and ciprofloxacin on cardiac action potential duration显示文摘 | Patmore L Fraser S Mair D | 2000 | Eur J Pharmacol2000，406，3： | 1 |
| 17 | Child o- verweight in France and its relationship with physical activity, sed- entary behaviour and socioeconomic status 显示文摘 | S Lioret B Maire J - L Volatier and M - A Charles | 2007 | European Journal of Clinical Nutrition2007，，61： | 1 |
| 18 | Impact of critical social empow- erment on psychological empowerment and job satisfaction in nursing and midwifery settings显示文摘 | Maire C Jean S Teresa O' Hara | 2010 | Journal of Nursing Manage- ment2010，18，： | 1 |
| 19 | Natriuretic peptides in assessment of left ventricular dysfunction 显示文摘 | Mair J Friedl W Thomas S | 1999 | Scand J Clin Lab Invest Suppl1999，230，： | 1 |
| 20 | Exendin- 4 decelerates food intake, weight gain, and fat Deposition in Zucker Rats显示文摘 | Margarzata S Maire ED Jennifer A | 2000 | Endocrinology2000，141，6： | 1 |
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