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| 1 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009，，9： | 2 |
| 2 | The contribution of voxel-based morphometry in staging patients with mild cognitive im- pairment显示文摘 | Bozzali M Filippi M Magnani G | 2006 | Neurology2006，67，： | 1 |
| 3 | Analysis of a failed alumina THR ball head 显示文摘 | Labanti M Magnani G | 1999 | Biomaterials1999，20，18： | 1 |
| 4 | Paclitaxel and docetaxel resistance: molecular mechanisms and development of new generation taxanes显示文摘 | Galletti E Magnani M Renzulli M L | 2007 | Chem Med Chem2007，2，7： | 1 |
| 5 | Paclitaxel and docetaxel resistance:molecular mechanisms and development of new eneration taxanes显示文摘 | Galletti E Magnani M Renzulli ML | | 0，，07： | 1 |
| 6 | Corrosion and wear studies of Cr3C2 - NiCr (HVOF) coatings sprayed on AA7050 T7 under cooling 显示文摘 | MAGNANI M SUEGAMA P H ESPALLARGAS N | 2009 | Journal of Thermal Spray Technology2009，，3： | 1 |
| 7 | Schema integration based on uncertain semantic mappings 显示文摘 | MAGNANI M RIZOPOULOS N BRIEN P | 2005 | Lec- ture Notes in Computer Science2005，，3716： | 1 |
| 8 | Potential isotopic and chemical markers for charactcrising organic fruits 显示文摘 | Camin F Perini M Bontcmpo L Fabroni S Faedl W Magnani S Baruzzi G Bonoli M Tabilio M R Musmeei S | 2011 | Food Chemistry2011，125，： | 1 |
| 9 | Biochemical charac- terization of two GALK1 mutations in patients with galactokinase deficiency 显示文摘 | Sangiuolo F Magnani M Stambolian D | 2004 | Hum Mutat2004，23，4： | 1 |
| 10 | Prevention of ventricuiar desynchronization by permanent para-Hisian pacing after atrioventricular node ablation in chronic atrial fibrillation:a crossover,blinded,randomized study versus apical right ventricular pacing显示文摘 | Occhetta E Bortaik M Magnani A | | 0，，10： | 1 |
| 11 | A survey on uncertainty management in data integration显示文摘 | Magnani M Montesi D | 2010 | Data and Information Quality2010，2，1： | 1 |
| 12 | The contribution of voxel-based morphometry in staging patients with mild cognitive impairment显示文摘 | Bozzali M Filippi M Magnani G | | 0，，03： | 1 |
| 13 | Corrosion and wear studies of NiCrCr3C2 HVOF coatings sprayed on AA7050 T7 under cooling显示文摘 | MAGNANI M SUEGAMA P H ESPALLARGAS N | 2009 | Journal of Thermal Spray Technology2009，18，3： | 1 |
| 14 | The Human Footprint in the Carbon Cycle of Temperate and Boreal Forests 显示文摘 | MAGNANI F MENCUCCINI M BORGHETTI M | 2007 | Nature2007，447，7146： | 1 |
| 15 | The contribution of voxel-based morphometry in staging patients with mild cognitive impairment显示文摘 | Bozzali M Filippi M Magnani G | 2006 | Neurology2006，67，3： | 1 |
| 16 | Optimized methodology for extraction of ( 1 - 3 )( 1 -6 )- β-D-glucan from Saccharomyces cerevisiae and in vitro evaluation of the cytotoxicity and genotoxicity of the corresponding carboxymethyl derivative 显示文摘 | Marciane Magnani Caroline M Calliari Fernando C de Macedo Jr | 2009 | Carbohydrate Polymers2009，，78： | 1 |
| 17 | Prevention of ventricular desynchronization by permanent para-hisian pacing after atrioventricular node ablation in chronic atrial fibrillation 显示文摘 | Occhetta E Bortnik M Magnani A | 2006 | J Am Clil Cardiol2006，47，： | 1 |
| 18 | The contribution of voxel-based morphometry in staging patients with mild cognitive impairment 显示文摘 | Bozzali M Filippi M Magnani G | 2006 | Neurology2006，67，3： | 1 |
| 19 | The use of magnetic nanoparticlesin the development of new molecular detection systems显示文摘 | Magnani M Galluzzi L Bruce L J | 2006 | Nanosci Nan-otechnol2006，6，8： | 1 |
| 20 | Ultrasonography detection of early bone erosions in the metacarpophalangeal joints of patients with rheumatoid arthritis显示文摘 | Magnani M Salizzoni E Mule R | 2004 | Clin Exp Rheumatol2004，22，： | 1 |
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