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| 1 | Coexistence of esophageal superficial carcinoma and multiple leiomyomas:A case report显示文摘平滑肌瘤是食管的最普通的良性瘤。他们通常作为单个损害或作为二或三个小瘤发生。仅仅包括超过 10 个小瘤的食道的多重平滑肌瘤的二个案例以前被报导了。而且,有食道的有鳞的房间癌覆闷死粘膜下层肿瘤的很少报告。我们描述作为有表面的食道的癌症与二或三个平滑肌瘤小瘤共存被诊断的一个 71 岁的人。在外科期间, 10 或一直不外科手术前地是明显的更多的小瘤在整个食管在粘膜下层和肌层是摸得出的。当食道的癌症的内部转移被怀疑,我们认为另外的淋巴是腺切除术,但是因为病人的严重血缺氧,不得不排除这种选择。显微镜检查表明所有小瘤是平滑肌瘤(20 损害,在直径的多达 3 厘米) ,并且癌房间的那侵略被限制到粘膜下层层 overlying 一个相对大的平滑肌瘤。这是与众多的独居的平滑肌瘤共存的表面的食道的癌症的第一份报告。多重极小的平滑肌瘤经常也在一个癌损害罐头的底作为内部转移,和一个平滑肌瘤被误诊作为肿瘤侵略被误诊。现在的案例证明那精确诊断与共存为病人的管理被要求表面的食道的癌症和多重平滑肌瘤。 | Takeshi Iwaya Chihaya Maesawa Noriyuki Uesugi Toshimoto Kimura Kenichiro Ikeda Yusuke Kimura Shingo Mitomo Kaoru Ishida Nobuhiro Sato Go Wakabayashi | 2006 | World Journal of Gastroenterology2006，12，28： | 7 |
| 2 | Liver cirrhosis induced by long-term administration of a daily low dose of amiodarone: A case report显示文摘The anti-arrhythmic agent amiodarone (AD) is associated with numerous adverse effects, but serious liver disease is rare. The improved safety of administration of daily low doses of AD has already been established and this regimen is used for long-term medication. Nevertheless,asymptomatic continuous liver injury by AD may increase the risk of step-wise progression of non-alcoholic fatty liver disease. We present an autopsy case of AD-induced liver cirrhosis in a patient who had been treated with a low dose of AD (200 mg/d) daily for 84 mo. The patient was a 85-year-old male with a history of ischemic heart disease.Seven years after initiation of treatment with AD, he was admitted with cardiac congestion. The total dose of AD was 528 g. Mild elevation of serum aminotransferase and hepatomegaly were present. Liver biopsy specimens revealed cirrhosis, and under electron microscopy numerous lysosomes with electron-dense, whorled, lamellar inclusions characteristic of a secondary phospholipidosis were observed. Initially, withdrawal of AD led to a slight improvement of serum aminotransferase levels, but unfortunately his general condition deteriorated and he died from complications of pneumonia and renal failure.Long-term administration of daily low doses of AD carries the risk of progression to irreversible liver injury. Therefore,periodic examination of liver function and/or liver biopsy is required for the management of patients receiving long-term treatment with AD. | Hiroki Oikawa Chihaya Maesawa Ryo Sato Kanta Oikawa Hiroyuki Yamada Seizo Oriso Sadahide Ono Akiko Yashima-Abo Koji Kotani Kazuyuki Suzuki Tomoyuki Masuda | 2005 | World Journal of Gastroenterology2005，11，34： | 4 |
| 3 | Cell - type - specific repression of the maspin gene is disrupted frequent- ly by demethylation at the promoter region in gastric intesti- nal metaplasia and cancer cells显示文摘 | Akiyama Y Maesawa C Ogasawara S | 2003 | Am J Pathol2003，163，5： | 1 |
| 4 | Consensus gene probes with conjugated 3 '-minor groove binder formonit oringminimal residual disease in acute lymphoblastie leukemia显示文摘 | Uehiyama M Maesawa C Yashima A | 2005 | Nucleic Acids Res2005，7，1： | 1 |
| 5 | Repeated radiosurgery for incompletely obliteraled arteriovenous malformations显示文摘 | Fliekinger JC Kondxiolka D | 2000 | J Neurosurg2000，92，6： | 1 |
| 6 | Mutations in mitochondrial control region DNA in gastric tumours of Japanese patients显示文摘 | Tamura G Nishizuka S Maesawa C | 1999 | Euro J Cancer1999，35，2： | 1 |
| 7 | Effects of opening pe- fitumoralsy rinxesonm ot orevo kedpotenfial sduring resection of anintramedulIaryspinalcordtumor asereport显示文摘 | Maesawa S Takayasu M Kajita Y | 2004 | NeurolMed- Chir(Tokyo)2004，44，5： | 1 |
| 8 | Prevention of critical telomere shortening by oestradiol in human normal hepatic cultured cells and carbon tetrachloride induced rat liver fibrosis显示文摘 | Sato R Maesawa C Fujisawa K | 2004 | Gut2004，53，7： | 1 |
| 9 | Cell-type-specific repression of the Maspin gene is disrupted frequently by demethylation at the promoter region in gastric intestinal metaplasia and cancer cells显示文摘 | Akiyama Y Maesawa C Ogasawara S | 2003 | Am J Pathol2003，163，5： | 1 |
| 10 | Effect of atorv- astatin on microRNA 221/222 expression in endothelial pro- genitor cells obtained from patients with coronary artery dis- ease显示文摘 | MINAMI Y SATOH M MAESAWA C | 2009 | Eur J Clin Invest2009，39，5： | 1 |
| 11 | Cell-Type-Specific Repression of the Maspin Gene Is Disrupted Frequently by Demethylation at the Promoter Region in Gastric Intestinal Metaplasia and Cancer Cells显示文摘 | Yuji Akiyama Chihaya Maesawa Satoshi Ogasawara | 2003 | American Journal of Pathology2003，163，5： | 1 |
| 12 | Epigenetic modi- fication is involved in aberrant expression of class 11I - tu- bulin,TUBB3, in ovarian cancer cells 显示文摘 | Izutsu N Maesawa C Shibazaki M | 2008 | Int J Oncol2008，32，： | 1 |
| 13 | Human PinXl, a potent telomerase inhibitor, is not involved in human gastrointestinal tract carcinoma 显示文摘 | Akiyama Y Maesawa C Wada K | 2004 | Oncol Rep2004，11，4： | 1 |
| 14 | Effect of atorva- statin on microRNA 221/222 expression in endothelial progenitor cells obtained from patients with coronary arterydisease显示文摘 | Minami Y Satoh M Maesawa C | 2009 | Eur J Clin Invest2009，39，5： | 1 |
| 15 | Prevention of critical telomere shortening by oestradiol in human normal hepatic cultured cells and carbon tetrachloride induced rat liver fibrosis 显示文摘 | SatoR Maesawa C Fujisawa K Wada K | 2004 | Gut2004，53，： | 1 |
| 16 | Downregula- tion of miR-138 is associated with overexpression of hu- man telomerase reverse transcriptase protein in human anaplastic thyroid carcinoma cell lines 显示文摘 | Mitomo S Maesawa C Ogasawara S | 2008 | Cancer Sci2008，99，2： | 1 |
| 17 | Effect of atorvastatin on microRNA 221/222 expression in endothelial progenitor cells obtained from patients with coronary artery disease显示文摘 | Minami Y Satoh M Maesawa C | 2009 | Eur J Clin Invest2009，39，5： | 1 |
| 18 | Clinical outcomes after stereotactic radiosurgery for idiopathic trigeminal neuralgia显示文摘 | Maesawa S Salame C Flickinger JC | 2001 | J Neurosurg2001，94，1： | 1 |
| 19 | Aberrant maspin expression in human endometrial cancer显示文摘 | Murai S Maesawa C Masuda T | 2006 | Cancer Sci2006，97，9： | 1 |
| 20 | Effect of atorvastatin on microRNA 221/222 expression in endothelial progenitor cells obtained from patients with coronary artery disease显示文摘 | Minami Y Satoh M Maesawa C | | 0，，： | 1 |
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