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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Ignition and devolatilization of pulverized bituminous coal particles during oxygen/carbon dioxide coal combustion显示文摘 | Molina A Shaddix C R | 2007 | Proceedings of the Combus- tion Institute2007，21，2： | 1 |
| 3 | Nitrogen leaching and denitrification in continuous corn as related to residue management and nitrogen fertilization显示文摘 | GOLLANY H T MOLINA J A CLAPP C E | 2004 | Environmental Management2004，33，： | 1 |
| 4 | A comparative study using two methods to produce zeolites from fly ash显示文摘 | A Molina C Poole | 2003 | Minerals Engineering2003，，2： | 1 |
| 5 | Particle imaging of ignition and devolatilization of pulverized coal during oxy-fuel combus- tion显示文摘 | Shaddix C R Molina A | 2009 | Proceedings of the Combustion Institute2009，32，2： | 1 |
| 6 | A comparative study using two meth- ods to produce zeolites from fly ash 显示文摘 | Molina A Poole C | 2004 | Minerals Engi- neering2004，17，： | 1 |
| 7 | Particle imaging of ignition and devolatilization of pulverized coal during oxy-fuel com- bustion显示文摘 | Shaddix C R Molina A | 2009 | Proceedings of the Combustion Institute2009，32，2： | 1 |
| 8 | A characterization of Quasi-copulas显示文摘 | Genest C Quesada Molina J J Rodriguez-Lallena J A | 1999 | J Multivariate Analysis1999，69，2： | 1 |
| 9 | Framework for global virtual business 显示文摘 | MOLINA A PONGTA S BREMER C F | 1998 | Agility and Global Competition1998，2，3： | 1 |
| 10 | Patterns and predic tots of early risk of recurrence after transient ischemic attack with respect to etiologic subtypes显示文摘 | Purroy F Montaner J Molina C A | 2007 | Stroke2007，38，12： | 1 |
| 11 | Problem and pathological gambling are associated with poorer mental and physical health in older adults显示文摘 | ERICKSON L MOLINA C A LADD G T | 2005 | Int J Geriatric Psych2005，20，8： | 1 |
| 12 | Heart stroke volume and cardiac output by four-dimensional ultrasound in normal fetuses显示文摘 | Molina FS Faro C Sotiriadis A | | 0，，02： | 1 |
| 13 | Bayesian resolution enhancement of compressed video显示文摘 | SEGALL C A KATSAGGELOS A A MOLINA R | 2004 | IEEE Trans on Image Processing2004，13，7： | 1 |
| 14 | Effect of CO2 gasification reaction on oxy-combustion of pulverized coal char显示文摘 | Hecht E S Shaddix C R Molina A | | 0，，2： | 1 |
| 15 | Differentialsynthesis of fermentative aroma compounds of two related commercialwine yeast strains显示文摘 | MOLINA A M GUADALUPE V VARELA C | 2009 | Food Chemistry2009，117，2： | 1 |
| 16 | G-Dominance: reference point based dominance for multi-objective metaheuristics 显示文摘 | MOLINA J SANTANA L V COELLO C A C | 2009 | European Journal ofOperational Research2009，197，2： | 1 |
| 17 | A comparison of Al-Fe and Zr- Fe pillared clays for catalytic wet peroxide oxidation 显示文摘 | Molina C B Casas J A Zazo J A | 2006 | Chem Eng J2006，，118： | 1 |
| 18 | Ignition and devolatilizationof pulverized bituminous coal particles during oxy-gen/carbon dioxide coal combustion显示文摘 | Molina A Shaddix C R | 2007 | Proceedingsof the Combustion Institute2007，31，2： | 1 |
| 19 | Patterns and predictorsof early risk of recurrence after transient ischemic attack with re-spect to etiologic subtypes显示文摘 | Purroy F Montaner J Molina C A | 2007 | Stroke2007，38，12： | 1 |
| 20 | Delayed on set of paralysis and slowed tumor growth following in situ place ment of recombinant human bone morphogenetic protein 2 within spine tumors in a rat model of metastatic breast cancer显示文摘 | Molina C A Sarabia Estrada R Gokaslan Z L | 2012 | J Neuro surg Spine2012，16，4： | 1 |
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