维普中文期刊产品整合服务
2篇 您的检索式:作者名="MIN Weifang"
    题名 作者 年代 出处 被引量
1Education and intergenerational income mobility in urban China显示文摘利用北京大学教育经济研究所《中国城镇居民教育与就业情况调查—2004》的数据,对中国城镇居民教育与收入代际流动的关系进行定量研究。通过收入代际继承性和流动性指数、收入代际弹性系数等指标分析中国城镇居民收入代际流动的特点,运用通径分析技术和二元Logistic回归模型探讨教育促进收入代际流动的功能,分析教育的这一功能随中国市场化水平的提高所呈现出的变化趋势,并对研究结果进行原因解释。研究结果表明,中国城镇居民收入代际存在较为明显的传递效应,多数子女依然滞留在与父亲相同的收入组群;教育作为一种重要的代际流动机制,有助于促进弱势群体的子女实现经济社会地位的跃升,具有较强的促进代际流动的功能;随着市场化水平的提高,教育促进收入代际流动,改善整个社会收入公平状况的功能也日益增强。GUO Congbin MIN Weifang 2008Frontiers of Education in China2008,3,1:2
2Single-cell RNA sequencing reveals the developmental program underlying proximal–distal patterning of the human lung at the embryonic stage显示文摘The lung is the primary respiratory organ in human, in which the proximal airway and the distal alveoli are responsible for air conduction and gas exchange, respectively. However, the regulation of proximal–distal patterning at the embryonic stage of human lung development is largely unknown. Here we investigated the early lung development of human embryos at weeks 4–8 post fertilization (Carnegie stages 12–21) using single-cell RNA sequencing, and obtained a transcriptomic atlas of 169,686 cells. We observed discernible gene expression patterns of proximal and distal epithelia at week 4, upon the initiation of lung organogenesis. Moreover, we identified novel transcriptional regulators of the patterning of proximal (e.g., THRB and EGR3) and distal (e.g., ETV1 and SOX6) epithelia. Further dissection revealed various stromal cell populations, including an early-embryonic BDNF+ population, providing a proximal–distal patterning niche with spatial specificity. In addition, we elucidated the cell fate bifurcation and maturation of airway and vascular smooth muscle progenitor cells at the early stage of lung development. Together, our study expands the scope of human lung developmental biology at early embryonic stages. The discovery of intrinsic transcriptional regulators and novel niche providers deepens the understanding of epithelial proximal–distal patterning in human lung development, opening up new avenues for regenerative medicine.Shangtao Cao Huijian Feng Hongyan Yi Mengjie Pan Lihui Lin Yao Santo Zhang Ziyu Feng Weifang Liang Baomei Cai Qi Li Zhi Xiong Qingmei Shen Minjing Ke Xing Zhao Huilin Chen Qina He Mingwei Min Quanyou Cai He Liu Jie Wang Duanqing Pei Jiekai Chen Yanlin Ma 2023Cell Research2023,33,6:0
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费