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| 1 | Lymphangiogenesis:A new player in cancer progression显示文摘Lymph node metastasis is the hallmark of colon cancer progression,and is considered one of the most important prognostic factors.Recently,there has been growing evidence that tumor lymphangiogenesis(formation of new lymphatic vessels) plays an important role in this process.Here,we review the latest f indings of the role of lymphangiogenesis in colorectal cancer progression,and discuss its clinical application as a biomarker and target for new therapy.Understanding the molecular pathways that regulate lymphangiogenesis is mandatory to pave the way for the development of new therapies for cancer.In the future,tailored treatments consisting of combinations of chemotherapy,other targeted therapies,and anti-lymphangiogenesis agents will hopefully improve patient outcomes.This progression to the clinic must be guided by new avenues of research,such as the identif ication of biomarkers that predict response to treatment. | Masayuki Nagahashi Subramaniam Ramachandran Omar M Rashid Kazuaki Takabe | 2010 | World Journal of Gastroenterology2010,16,32: | 14 |
| 2 | Inverted Meckel's diverticulum as a cause of occult lower gastrointestinal hemorrhage显示文摘Meckel's diverticulum is a common asymptomatic congenital gastrointestinal anomaly,but rarely it can present with hemorrhage.Over the last few years inverted Meckel's diverticulum has been reported in the literature with increasing frequency as an occult source of lower gastrointestinal hemorrhage.Here,we report a case of a 54-year-old male,who was referred for surgical evaluation with persistent anemia and occult blood per rectum after a work up which failed to localize the source over 12 mo,including upper and capsule endoscopy,colonoscopy,enteroclysis,Meckel scan,and tagged nuclear red blood cell scan.An abdominal computed tomography scan showed a possible mid-ileal intussusception and intraluminal mass.During the abdominal exploration,inverted Meckel's diverticulum was diagnosed and resected.We review the literature,discuss the forms in which the disease presents,the diagnostic modalities utilized,pathological findings,and treatment.Although less than 40 cases have been reported in the English literature from 1978 to 2005,19 cases have been reported in the last 6 years alone(2006-2012) due to improved diagnostic modalities.Successful diagnosis and treatment of this disease requires a high index of clinical suspicion,which is becoming increasingly relevant to general gastroenterologists. | Omar M Rashid Joseph K Ku Masayuki Nagahashi Akimitsu Yamada Kazuaki Takabe | 2012 | World Journal of Gastroenterology2012,18,42: | 7 |
| 3 | A NEW FLAVONE C-GLYCOSIDE FROM SCUTELLARIA BAICALENSIS显示文摘ANEWFLAVONEC-GLYCOSIDEFROMSCUTELLARIABAICALENSIS¥YongYuZHANG;XianLI;YunZhenGOU(ShenyangPharmaceuticalUniversity,Shenyang11001... | Yong Yu ZHANG Xian LI Yun Zhen GOU(Shenyang Pharmaceutical University, Shenyang 110015)Yoshihiro HARIGAYA, Masayuki ONDASchool of Pharmaceutical Sciences, Kitasato University, Tokyo 108 ,JapanKadsunort H^SHIMO’rO, yukinobu iK EYA, Minoru OKAD^, cacao M^ | 1994 | Chinese Chemical Letters1994,5,10: | 3 |
| 4 | Novel interaction of the voltage-dependent sodium channel (VDSC) with calmodulin: does VDSC acquire calmodulin-mediated Ca2+-sensitivity?显示文摘 | Masayuki M Takashi K Takeaki O | 2000 | Biochemistry2000,39,6: | 1 |
| 5 | Incorporation of soy milk lipid into protein coagulum by addition of calcium chloride显示文摘 | Guo S T Tomotada O Masayuki M | | 0,,: | 1 |
| 6 | Transdemal ketoprofen mitigates the severity of postoperative sore throat显示文摘 | Masayuki O Kouichiro M Takeyoshi S | 2004 | Can J Anesth2004,45,11: | 1 |
| 7 | Transdemal ketoprofen mitigates the severity of postoperative sore throat 显示文摘 | Masayuki O Kouichiro M Takeyoshi S | 2004 | Can J Anesth2004,45,11: | 1 |
| 8 | Effect of temperature and photoperiod on phytotoxic root exudates of cucumber (Cucumis sativus) in hydroponic culture显示文摘 | PRAMANIK M H R MASAYUKI N TOSHIKI A YOSHIHISA M | 2000 | Journal of Chemical Ecology2000,26,8: | 1 |
| 9 | Fiber-based all-optical regeneration of DPSK signals degraded by transmission in a fiber 显示文摘 | MASAYUKI M YASUTAKA M | 2009 | Optics express2009,17,8: | 1 |
| 10 | Long-Term Beneficial Effect of Late Reperfusion for Acute Anterior Myocardial Infarction With Percutaneous Transluminal Coronary Angioplasty显示文摘 | Hajime H Masayuki T Kazuo M | 1998 | Circulatiort1998,98,22: | 1 |
| 11 | Phylogenetic relationships between toxic and non-toxic strains of the genus Microcystis based on 16S to 23S internal transcribed spacer sequence显示文摘 | Shigeto Otsuka Shoichiro Suda Renhui Li Masayuki Watanabe Hiroshi Oyaizu Satoshi Matsumoto Makoto M Watanabe | 1999 | FEMS Microbiology Letters1999,,1: | 1 |
| 12 | Measurement of plastic strain of polycrystalline material by electron backscatter diffraction 显示文摘 | Masayuki Kamaya Wilkinsonb A J John M T | 2005 | Nuclear Engineering and Design2005,,235: | 1 |
| 13 | Inhibition ofangiogenesis and HIF-1αactivity by antimycin A1显示文摘 | Masayuki M Yuki H Kiyoshi E | 2006 | Biol Pharm Bull2006,29,: | 1 |
| 14 | Numerical simulation of rrletallie solid bridging particles in a fluidized bed at high temperature 显示文摘 | KENYA K TAKAFUMI M MASAYUKI H | 2000 | Powder technology2000,109,3: | 1 |
| 15 | 1 -Deoxyrubralactone, a novel specific inhibitor offamilies X and Y of eukaryotic DNA polymerasesfrom a fungal strain derived from sea algae 显示文摘 | MITSUKI N MASAYUKI N YOSHIYUKI M etal | 2008 | Bioorg Med Chem2008,16,6: | 1 |
| 16 | Electric double- layer capacitor composed of activated carbon fiber cloth electrodes and solid polymer electrolytes containing al- kylammonium salts 显示文摘 | Masashi I Masayuki M Mitsuo I | 1994 | J Electrochem Soc1994,141,7: | 1 |
| 17 | Absolute stereostructure of potent α-glucosidase inhibitor salacinol,with unique thiosugar sulfonium sulfate inner salt structure from Salacia reticulata显示文摘 | Masayuki Y Toshi M Hisashi M | 2002 | Bioorg Med Chem2002,10,: | 1 |
| 18 | Extracapsular invasion of small hepatocellular carcinoma: MR and CT findings 显示文摘 | Takeyoshi I Masayuki K Ryozo M | 1994 | JCAT1994,18,5: | 1 |
| 19 | Properties of a reversible soluble- insoluble cellulase and its appieation to repeated hydrolysis of crystalline cellulose显示文摘 | MASAYUKI T KUMAKURA M | 1989 | Biotecbnol Bioeng1989,34,10: | 1 |
| 20 | Poly(2-methacryloyloxyethylphosphorylcholine)grafting and vitamin E blendingfor high wear resistance and oxidative stability of orthopedicbearings显示文摘 | Masayuki K Toru M Shihori Y | 2014 | Biomaterials2014,35,: | 1 |