|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Lymphocyte subsets predictive value and possible involvement of human papilloma virus infection on breast cancer molecular subtypes显示文摘AIM To detect human papilloma virus(HPV) presence and to characterize cellular immune response in breast cancer patients. METHODS A total of 74 women were included, of which 48 samples were from patients diagnosed with breast cancer and 26 patients with benign pathology of the breast. Molecular subtype classification was performed based on the immunohistochemical reports of the tumor piece. HPV genome detection and genotyping from fresh breast biopsies was performed using the INNO-LIPA HPV Genotyping Extra test(Innogenetics, Ghent, Belgium). CD3+, CD4+, CD8+ and natural killer(NK)+ cells levels from peripheral blood samples from patients with breast cancer and benign pathology were measured by flow cytometry. RESULTS Luminal A was the most frequent breast cancer molecular subtype(33.33%). HPV was detected in 25% of the breast cancer patients, and genotype 18 was the most frequent in the studied population. The mean of CD3+, CD4+ and CD8+ subpopulations were decreased in patients with breast cancer, in relation to those with benign pathology, with a statistically significant difference in CD8+ values(P = 0.048). The mean of NK+ cells was increased in the benign pathology group. The average level of CD3+, CD4+, CD8+ and NK+ cells decreased as the disease progressed. HER2+ and Luminal B HER2+ tumors had the lowest counts of cell subsets. HPV breast cancer patients had elevated counts of cellular subsets. CONCLUSION Determining level changes in cellular subsets in breast cancer patients is a useful tool to evaluate treatment response. | Andreína Fernandes Adriana Pesci-Feltri Isabel García-Fleury Marco López Vincent Guida Marisol De Macedo María Correnti | 2018 | World Journal of Clinical Oncology2018，9，7： | 5 |
| 2 | Laser sintering of Bi4Ti3O12 ferroelectric ceramics 显示文摘 | MACEDO Z S HERNANDES A C | 2002 | Mater Lett2002，55，： | 2 |
| 3 | Off-label drug prescribing in a Portuguese paediatric emergency unit显示文摘 | Ribeiro M Jorge A Macedo AF | 2013 | Int J Clin Pharm2013，35，1： | 1 |
| 4 | Mesoporous silica-magnetite nanocomposite synthesized by using a neutral surfactant显示文摘 | Souza K C Salazar-Alvarez G Ardisson J D Macedo W A A Sousa E M B | 2008 | Nanotechnology2008，19，18： | 1 |
| 5 | Pharmacological and phytochemical studies of callus culture extracts from Alternanthera brasiliana 显示文摘 | Macedo A F Barbosa N C Esquibel M A | 1999 | Pharmazie1999，54，10： | 1 |
| 6 | Tannase production by Paecilomyces variotii显示文摘 | VaniaB A Macedo D | 2007 | Bioresource Technology2007，98，： | 1 |
| 7 | Structural effects of WO3 incorporation on USY zeolite and applica- tion to free fatty acids esterification显示文摘 | Costa A A Braga P R S Macedo J L | 2012 | Microporous and Mesoporous Materials2012，147，1： | 1 |
| 8 | Statins for the primary prevention of cardiovascular disease显示文摘 | Taylor F Huffman M D Macedo A F | 2013 | Coehrane Database Syst Rev2013，1，01： | 1 |
| 9 | Immobilization of Fe, Mn and Co tetraphenylporphyrin complexes in MCM-41 and their catalytic activity in cyclohexene oxidation reaction by hydrogen peroxide 显示文摘 | COSTA A A GHESTI G F MACEDO J L BRAGA V S SANTOS M M DIAS J A DIAS S C L | 2008 | J Mol Catal A: Chem2008，282，： | 1 |
| 10 | Prediction of success in external cephalic version under toco- lysis: still a challenge显示文摘 | VAZ DE MACEDO C CLODE N MENDES DA GRA A L | 2015 | Acta Medica Portuguesa2015，28，5： | 1 |
| 11 | Two-level domain decomposition methods with Lagrange multipliers for the fast iterative solution of acoustic scattering problems显示文摘 | FARHAT C MACEDO A LESOINNE M | 2000 | Computer Methods in Applied Mechanics and Engineering2000，184，： | 1 |
| 12 | Hypospadias dilemmas:a round table显示文摘 | Snodgrass W Macedo A Hoebeke P | 2011 | J Pediatr Urol2011，7，2： | 1 |
| 13 | Ex vivo priming of naive T cells into EBV-specific Th1/Tc1 effector cells by mature autologous DC loaded with apoptotic/necrotic LCL显示文摘 | Macedo C Zeevi A | 2003 | Am J Transplant2003，3，11： | 1 |
| 14 | Mother's personality and in- fant temperament显示文摘 | Macedo A Marques M Bos S | 2011 | Infant Behav Dev2011，34，4： | 1 |
| 15 | Plant lipase from latex: proper- ties and industrial applications 显示文摘 | Paques F W Macedo G A | 2006 | Ouimica Nova2006，，29： | 1 |
| 16 | Technology, chemistry and microbiology of whey cheeses: review 显示文摘 | Malcata F X Macedo A Pintado M | 2001 | Food Science and Technology International2001，7，2： | 1 |
| 17 | ERIC-PCR genotyping of Haemophilus parasuis isolates from Brazilian pigs显示文摘 | Macedo N R Oliveira S R Lage A P | 2011 | Vet J2011，188，3： | 1 |
| 18 | Skovbrg P, Ramussen E UNIFAC prediction of vapor -liquid equilibria in mixed solvent-salt systems 显示文摘 | Macedo E A | 1990 | Chem Eng Sci1990，45，4： | 1 |
| 19 | Structure and magnetic properties of nanostructured Ni-ferrite显示文摘 | Albuquerque A S Ardisson J D Macedo W A A | 2001 | J Magn Magn Mater2001，，： | 1 |
| 20 | Increasing the antioxidant power of tea extracts by biotransformation of polyphenols显示文摘 | Macedo J A Battestin V Ribeiro M L | 2011 | Food Chemistry2011，126，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员