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| 1 | Comparison of Wirsung-jejunal duct-tomucosa and dunking technique for pancreatojejunostomy after pancreatoduodenectomy显示文摘Pancreato-enteric reconstruction after pancreatoduodenectomy (PD) is still a source of debate because of the high incidence of complications. Among the various types of pancreato-jejunostomies we don’t know yet which is the best in terms of anastomotic failure and related complications rates. Wirsung-jejunal duct-to-mucosa anastomosis (WJ) and 'dunking' pancreato-jejunal anastomosis (DPJ) are the two most used ones worldwide but conflicting results are reported. To determine which is the safer anastomosis and to define when an anastomosis should be preferred, we retrospectively reviewed two groups of patients who underwent WJ or DPJ. METHODS:Twenty-three patients underwent PD with WJ (n=17) with dilated (WJD) (n=9) or not-dilated Wirsung’s duct (WJND) (n=8) or with a DPJ (n=6) over a 3-year period at a single institution. RESULTS: The complications rate was high in all groups of patients (33.3% in WJD, 37.5% in WJND and 66.7% in DPJ). A pancreatic fistula developed in one patient in each group (11. 1% in WJD, 12. 5% in WJND and 16. 7% in DPJ). All these patients were managed conservatively. Anastomotic disruption took place in the WJ patients especially in the WJND group (n=2) compared to the WJD (n=1) (25% vs 11.1%) or DPJ groups (0%) : these three patients required a re-operation. Overall, the anastomotic defects were higher in patients who underwent WJND (37.5%), compared to WJD (22.2%) and to DPJ (16.7%). However, no statistical differences were found among the groups. Delayed gastric emptying (DGE) and total parenteral nutrition (TPN) along with anastomotic defects were responsible for a prolonged hospital stay. CONCLUSIONS:Our results were not able to demonstrate any statistical difference between the two different techniques in preventing anastomotic failure. WJ can represent a valid choice in case of a dilated duct and a firm, fibrotic enlarged gland that could not be properly invaginated in a small jejunal loop. DGE may occur in those patients who experienced an anastomotic failure and required a TPN regimen with a prolonged hospital stay. | Unita di Chirurgia, Dipartimento di Fisiopatologia Clinica (Batignani G, Fratini G, Zuckermann M and Tonelli F) and Dipartimento di Statistica (Bianchini E), Universitd degli Studi di Firenze, Flo rence, Italy | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 9 |
| 2 | Learning from students, inquiry into practice, and participation in professional communities: Beginning teachers' uneven progress toward equitable science teaching 显示文摘 | Bianchini J A & Cavazos L M | 2007 | Journal of Research in Science Teaching2007，，4： | 1 |
| 3 | Inside PageRank 显示文摘 | M Bianchini M Gori F Scarselli | 2005 | ACM Transactions on Internet Technology2005，5，1： | 1 |
| 4 | EphA2 reexpression prompts invasion of melanoma cells shifting from mesenchyrnal to amoeboid-like motility style显示文摘 | Parri M Taddei ML Bianchini F | 2009 | Cancer Res2009，69，5： | 1 |
| 5 | Learning without local minima in radial basis function networks显示文摘 | BIANCHINI M FRASCONI P GORI M | 1995 | IEEE Trans on Neural Networks1995，6，3： | 1 |
| 6 | Regulation of HMG-CoA reductase activity in plants显示文摘 | Stermer B A Bianchini G M Korth K L | 1994 | Journal of Lipid Research1994，35，7： | 1 |
| 7 | Middle ear problems in children hospitalised because of lower respiratory tract infections:a comparison between two cohorts in Burundi and Italy显示文摘 | Baggi E Semino M Bianchini S | 2013 | Int J Pediatr Otorhinolaryngol2013，77，12： | 1 |
| 8 | Learning without local minima in radial basis function networks显示文摘 | Bianchini M Frasconi p Gori M | 1995 | IEEE Trans Neural Networks1995，6，3： | 1 |
| 9 | Bamboo-dominated forests of the southwest Amazon: detection, spatial extent, life cycle length and flowering waves显示文摘 | de Carvalho A L Nelson B W Bianchini M C Plagnol D Kuplich T M Daly D C | 2013 | PLoS One2013，，54： | 1 |
| 10 | Learning without local minima in radial basis function networks显示文摘 | Bianchini M Fransconi P Gori M | 1995 | IEEE Transactions on Neural Networks1995，6，3： | 1 |
| 11 | Acute silver toxicity in aquatic animals is a function of sodium up- take rate 显示文摘 | Bianchini A Grosell M Gregory S M | 2002 | Environmental Science & Technology2002，36，8： | 1 |
| 12 | Learning without local minima in radial basis function networks 显示文摘 | Bianchini M Frasconi P Gori M | 1995 | IEEE Trans Neural Networks1995，6，3： | 1 |
| 13 | Metal-Hydride Alkynyl? Metal-Vinylidene Rearrangementsl-AlkyneSubstituent In Determining the Relative Stability of π -Alkyne, Hydride Alkynyl, and Vinylidene Forms at Cobalt显示文摘 | Bianchini C Peruzzini M Vacca A | 1991 | Organometallics1991，10，： | 1 |
| 14 | Stereochemical assign ment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1 显示文摘 | Arita M Bianchini F Aliberti J | 2005 | J Exp Med2005，201，5： | 1 |
| 15 | Diabetes,cardiovascular risk factors and idiopathic sudden sensorineural hearing loss:A case-control study显示文摘 | Aimoni C Bianchini C Borin M | | 0，，02： | 1 |
| 16 | Efficient and selective oxidation of methyl substituted cycloalkanes by heterogeneous methyltrioxorhenium-hydrogen peroxide sys- tems显示文摘 | Bianchini G Crucianelli M Canevali C | 2006 | Tetrahedron2006，62，12： | 1 |
| 17 | Catalytic MTO-based C--H insertion reactions of hydrogen perox- ide:an investigation on the polymeric support role in heter- ogeneous conditions 显示文摘 | Bianchini G Crucianelli M Canevali C | 2006 | Top Catal2006，40，14： | 1 |
| 18 | Phosphorylation of eIF4E by MNKs supports protein synthesis,cell cycle progression and proliferation in prostate cancer cells显示文摘 | BIANCHINI A LOIARRO M BIELLI P | 2008 | Carcinogenesis2008，29，12： | 1 |
| 19 | Kinetics of the combustion synthesis of TiB2 显示文摘 | Holt J B Kingman D D Bianchini G M | 1985 | Materials Science and Engineering1985，71，： | 1 |
| 20 | Inside PageRank显示文摘 | BIANCHINI M GORI M SCARSELLI F | 2005 | ACM Trans on Internet Technology2005，5，1： | 1 |
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