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| 1 | Efficacy and safety evaluation of intravenous infusion of cervus and cucumis polypeptides for treatment of avascular necrosis of the femoral head: a randomized clinical trial显示文摘OBJECTIVE: To investigate the efficacy and safety of intravenous cervus and cucumis polypeptides for treating avascular necrosis of the femoral head(ANFH) in regard to pain and hip function in a randomized clinical trial.METHODS: A total of 96 subjects with ANFH who were recruited at the Orthopaedic Hospital Affiliated with Hebei United University and Qian Hai Femoral Head Hospital of Beijing were assigned by lottery to an intervention group(n = 48) or a control group(n = 48). All subjects underwent physical therapy and rehabilitation exercises. In addition,subjects in the intervention group were given intravenous infusions of cervus and cucumis polypeptides. Visual analogue scale(VAS), Harris hip score,and radiography or magnetic resonance imaging were applied to assess all subjects at the beginning of treatment and 3, 6, and 9 months afterward. All the subjects were followed up for 2 years.RESULTS: At the beginning of treatment, there were no statistically significant differences between the two groups in terms of the general condition of patients or the VAS and Harris hip scores(all P > 0.05). At 3, 6, and 9 months after treatment,however, the VAS score decreased and the Harris hip score increased in all patients, with the improvement of intervention group significantly greater than that of the control group(P < 0.05).The total effectiveness rates for the intervention and control groups were 89.58% and 70.83%, respectively, with the difference being statistically significant(P < 0.05). There was no statistically significant difference between the two groups in terms of the safety of the injections(P > 0.05).CONCLUSION: Intravenous infusion of cervus and cucumis polypeptides relieved pain and improved hip function of subjects with ANFH.Thus, the intravenous infusion of cervus and cucumis polypeptides was a safe, effective treatment for ANFH. | Wei Liyou Zhang Hongwei Li Xinmin Yang Chunyan Wang Guoqiang Zhang Lifeng Cui Mingwu Han Lijun | 2016 | Journal of Traditional Chinese Medicine2016，36，1： | 15 |
| 2 | Protective effect of Xuebijing injection on myocardial injury in patients with sepsis: a randomized clinical trial显示文摘OBJECTIVE: To investigate the protective effect and possible mechanism of Xuebijing Injection on myocardial injury in patients with sepsis, and to evaluate its prognostic implications.METHODS: Patients with septic myocardial injury were recruited, and were randomly divided into two groups: treatment group and control group. All patients in two groups received conventional cluster treatment, the patients in treatment group additional received Xuebijing injection dissolved in0.9% sodium chloride injection, and the patients in control group received the same amount of 0.9%sodium chloride injection. At the beginning of treatment and 3, 7 and 10-day after treatment, lab-oratory indicators of cardiac troponin Ⅰ(cTnI),N-terminal pro B-type natriuretic peptide(NT-pro BNP) and procalcitonin(PCT) were respectively tested in venous blood. The patient's length of stay in Intensive Care Unit(ICU) and the mortality in 28 days were recorded.RESULTS: At 3, 7 and 10-day after treatment, the improvements of c Tn I, NT-pro BNP and PCT in treatment group were better than those in control group, and the differences were statistically significant(P < 0.05). The mortality of treatment group in28 days was not significantly different from that of control group(P > 0.05). The ICU length of stay of treatment group was shorter than that of control group(P > 0.05).CONCLUSION: Xuebijing injection could improve the levels of c Tn I, NT-pro BNP and PCT in patients with septic myocardial injury.and it had a protective effect on myocardial injury. | Zhang Hongwei Wei Liyou Zhao Gang Liu Shuzheng Zhang Zhenyu Zhang Jing Yang Yajing | 2016 | Journal of Traditional Chinese Medicine2016，36，6： | 7 |
| 3 | Numerical study of mono-crystalline silicon solar cells with passivated emitter and rear contact configuration for the efficiency beyond 24% based on mass production technology显示文摘Mono-crystalline silicon solar cells with a passivated emitter rear contact(PERC)configuration have attracted extensive attention from both industry and scientific communities.A record efficiency of 24.06%on p-type silicon wafer and mass production efficiency around 22%have been demonstrated,mainly due to its superior rear side passivation.In this work,the PERC solar cells with a p-type silicon wafer were numerically studied in terms of the surface passivation,quality of silicon wafer and metal electrodes.A rational way to achieve a 24%mass-production efficiency was proposed.Free energy loss analyses were adopted to address the loss sources with respect to the limit efficiency of 29%,which provides a guideline for the design and manufacture of a high-efficiency PERC solar cell. | Peng Wang Gaofei Li Miao Wang Hong Li Jing Zheng Liyou Yang Yigang Chen Dongdong Li Linfeng Lu | 2020 | Journal of Semiconductors2020，41，6： | 2 |
| 4 | Oxidation of ZrC–30vol% SiC composite in air from low to ultrahigh temperature显示文摘 | Liyou Zhao Dechang Jia Xiaoming Duan Zhihua Yang Yu Zhou | 2011 | Journal of the European Ceramic Society2011，，： | 1 |
| 5 | Low temperature sintering of ZrC–SiC composite显示文摘 | Liyou Zhao Dechang Jia Xiaoming Duan Zhihua Yang Yu Zhou | 2011 | Journal of Alloys and Compounds2011，，41： | 1 |
| 6 | Recombination function and recombination kinetics of Escherichia coli single-stranded DNA-binding protein显示文摘It is unknown whether the ss DNA-binding-protein(SSB) possesses the ability to catalyze DNA recombination.We investigated the recombination function of SSB and the recombination kinetics of Escherichia coli using a new transformation method with a modified double-layered plate.We found that SSB catalysed intermolecular recombination in vitro.Its intermolecular recombination rate versus substrate concentration or homologous sequence length fitted the Hill equation,and while the plasmid intramolecular recombination rate versus substrate concentration fitted a positively linear correlation,the dominant intermolecular recombination was a non-homologous recombination in vivo,similar to Rec A.However,ssb-dependent recombination occurred later and at a lower recombination rate than the rec A-dependent,probably because ssb expression was about two-fold lower than rec A during the E.coli earlier growth stage.The affinity to substrate and the recombination efficiency of SSB was lower than Rec A,whereas SSB enhanced the catalytic efficiency of Rec A.Knocking out both rec A and ssb led to loss of recombination.Our results confirmed that as SSB has the recombination function itself as an allosteric enzyme,rec Aindependent recombination in E.coli should be ssb-dependent.ssb-dependent recombination may be the third DNA double-strand break repair pathway,in addition to rec Adependent recombination and non-homologous end joining. | Ran Chai Chaohui Zhang Fang Tian Huiru Li Qianlong Yang Andong Song Liyou Qiu | 2016 | Science Bulletin2016，61，20： | 1 |
| 7 | Oxidation of ZrC–30vol% SiC composite in air from low to ultrahigh temperature显示文摘 | Liyou Zhao Dechang Jia Xiaoming Duan Zhihua Yang Yu Zhou | 2011 | Journal of the European Ceramic Society2011，，4： | 1 |
| 8 | Climate warming restructures seasonal dynamics of grassland soil microbial communities显示文摘Soil microbial community's responses to climate warming alter the global carbon cycle.In temperate ecosystems,soil microbial communities function along seasonal cycles.However,little is known about how the responses of soil microbial communities to warming vary when the season changes.In this study,we investigated the seasonal dynamics of soil bacterial community under experimental warming in a temperate tall‐grass prairie ecosystem.Our results showed that warming significantly(p=0.001)shifted community structure,such that the differences of microbial communities between warming and control plots increased nonlinearly(R^(2)=0.578,p=0.021)from spring to winter.Also,warming significantly(p<0.050)increased microbial network complexity and robustness,especially during the colder seasons,despite large variations in network size and complexity in different seasons.In addition,the relative importance of stochastic processes in shaping the microbial community decreased by warming in fall and winter but not in spring and summer.Our study indicates that climate warming restructures the seasonal dynamics of soil microbial community in a temperate ecosystem.Such seasonality of microbial responses to warming may enlarge over time and could have significant impacts on the terrestrial carbon cycle. | Xue Guo Mengting Yuan Jiesi Lei Zhou Shi Xishu Zhou Jiabao Li Ye Deng Yunfeng Yang Liyou Wu Yiqi Luo James MTiedje Jizhong Zhou | 2022 | mLife2022，1，3： | 1 |
| 9 | Onshore Contribution to the Microbial Communities in the Lakes on the Qing-Tibetan Plateau显示文摘The inland lakes on the Tibetan Plateau are inhabited by diverse microbial communities,which play a significant role in biogeochemical cycles of biogenic elements(e.g.carbon,nitrogen).Onshore inputs provide | JIANG Hongchen YANG Jian DONG Hailiang MA Li'an WU Liyou ZHOU Jizhong | 2014 | Acta Geologica Sinica(English Edition)2014，88，S1： | 0 |
| 10 | Microbial Succession in Response to Salinity in the Sediments of Lakes on the Northeastern Qinghai-Tibetan Plateau,China显示文摘Salinity is an important factor controlling the microbial distribution in lakes.However little is known about how microbial communities evolve in response to salinity variation.In this study,we investigated the | YANG Jian JIANG Hongchen DONG Hailiang MA Li'an WU Liyou ZHOU Jizhong | 2014 | Acta Geologica Sinica(English Edition)2014，88，S1： | 0 |
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