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| 1 | Flight safety oriented ice shape modulation using distributed plasma actuator units显示文摘Ice accretion on the wings seriously threatens the flight safety of an aircraft.From the perspectives of ensuring flight safety and saving power consumption,the ice shape modulation method using distributed plasma is proposed.Distributed plasma actuator units are designed to modulate the spanwise continuous ice at the leading edge into periodically segmented ice pieces,forming a wavy leading edge.Both airfoil and scaled aircraft model,with continuous and modulated ice,are experimentally investigated and simulated.Compared with the continuous ice,ice shape modulation can significantly improve the aerodynamic performance,flight control characteristics and flight safety.This method can save about half electric power,which is very beneficial for application. | Yun WU Biao WEI Hua LIANG Like XIE Zhe LI Yinghong LI | 2021 | Chinese Journal of Aeronautics2021，34，10： | 5 |
| 2 | Cell viability and dopamine secretion of 6-hydroxydopamine-treated PC12 cells co-cultured with bone marrow-derived mesenchymal stem cells显示文摘In the present study, PC12 cells induced by 6-hydroxydopamine as a model of Parkinson's Disease, were used to investigate the protective effects of bone marrow-derived mesenchymal stem cells bone marrow-derived mesenchymal stem cells against 6-hydroxydopamine-induced neurotoxicity and to verify whether the mechanism of action relates to abnormal α-synuclein accumulation in cells. Results showed that co-culture with bone marrow-derived mesenchymal stem cells enhanced PC12 cell viability and dopamine secretion in a cell dose-dependent manner. MitoLight staining was used to confirm that PC12 cells co-cultured with bone marrow-derived mesenchymal stem cells demonstrate reduced levels of cell apoptosis. Immunocytochemistry and western blot analysis found the quantity of α-synuclein accumulation was significantly reduced in PC12 cell and bone marrow-derived mesenchymal stem cell co-cultures. These results indicate that bone marrow-derived mesenchymal stem cells can attenuate 6-hydroxydopamine-induced cytotoxicity by reducing abnormal α-synuclein accumulation in PC12 cells. | Yue Tang Yongchun Cui Fuliang Luo Xiaopeng Liu Xiaojuan Wang Aili Wu Junwei Zhao Zhong Tian Like Wu | 2012 | Neural Regeneration Research2012，7，14： | 3 |
| 3 | Application of sodium alginate microspheres in ischemic stroke modeling in miniature pigs显示文摘The miniature pig is an optimal animal model for studying nervous system disease because of its physiologic and pathologic features. However, the rete mirabile composed of arteries and veins at the skull base limits their application as a model of ischemic stroke by middle cerebral artery occlusion. The present study investigated the possibility of establishing an ischemic stroke model in the miniature pig by blocking the skull base retia with sodium alginate microspheres. Three Bama miniature pigs were used. Using the monitor of C-arm X-ray machine, sodium alginate microspheres (100-300 μm), a novel embolic material, were injected through the femoral artery, aortic arch, common carotid artery, ascending pharyngeal artery and the retia. Results were evaluated using carotid arteriography, MRI, behavior observation and histology. The unilateral rete mirabile was completely blocked, resulting in disturbance in blood supply to the basal ganglia, astasia of the right hind limb and salivation. MRI and hematoxylin-eosin staining showed an evident infarction focus in the basal ganglia. These findings indicate that sodium alginate microspheres are a suitable embolic material for blocking the skull base retia in miniature pigs to establish an ischemic stroke models. | Yongchun Cui Yi Tian Yue Tang Liujun Jia Aili Wu Peng Peng Jianzhong Yang Hong Du Xiaojuan Wang Like Wu | 2013 | Neural Regeneration Research2013，8，16： | 2 |
| 4 | Improving aircraft aerodynamic performance with bionic wing obtained by ice shape modulation显示文摘For Unmanned Aerial Vehicles(UAVs)with limited electrical power to achieve effectively anti-/de-icing at the leading edge of the wing,a strategy of ice shape modulation was proposed.Isolated simulated ice shape pieces printed by 3D printing technology are mounted on a NACA0012 finite wing model,and its lift/drag coefficients and suction-side velocity fields are measured by the six-component force balance and the Particle Imaging Velocimetry(PIV),respectively.The ratio of the spanwise length of a single ice shape piece to chord length and the spanwise length of the non-icing area between the two adjacent single ice shape pieces are defined as dimensionless ice shape length(w/c)and dimensionless modulation ratio(w/λ),respectively.The results indicate that for a fixed w/λ,the wing lift coefficient first increases and then drops with increasing w/c,and a peak value exists when w/c is between 0.1 and 0.2.The lower the w/λis,the higher the wing lift coefficient will be.The periodical variation of the flow separation area along the spanwise direction is attributed on the one hand to the acceleration effect of the flow field in the non-icing area which reduces the separation area,and on the other hand to the cross-flow caused by the streamwise vortices from the non-icing area to the icing area which promotes the mixing of the flow field(similar to vortex generators).The obtained modulation law is verified through flight tests and provides guidance for the use of ice shape modulation scheme for UAVs that cannot be completely anti-/deicing under severe weather conditions. | Like XIE Hua LIANG Haohua ZONG Yun WU Yinghong LI Zhi SU Xuecheng LIU | 2023 | Chinese Journal of Aeronautics2023，36，2： | 1 |
| 5 | Gelatin shells strengthen polyvinyl alcohol core–shell nanofibers显示文摘 | Valerie Merkle Like Zeng Weibing Teng Marvin Slepian Xiaoyi Wu | 2013 | Polymer2013，，21： | 1 |
| 6 | SMSE waveform design using soft decision selection and dynamic assignment of subearrier modula- tion order and power 显示文摘 | LIKE E C TEMPLE M A WU Z | 2009 | Journal of Communications2009，4，10： | 1 |
| 7 | Assessment of EDTA heap leaching of an agricultural soil highly contaminated with heavy metals显示文摘 | Pengjie Hu Bingfan Yang Changxun Dong Like Chen Xueying Cao Jie Zhao Longhua Wu Yongming Luo Peter Christie | 2014 | Chemosphere2014，，： | 1 |
| 8 | Reliable Modulation Classification at Low SNR Using Spectral Correlation显示文摘 | LIKE E CHAKRAVARTHY V WU Z Q | 2007 | IEEE2007，，4： | 1 |
| 9 | The Modular Configura- tion System Based on Case-Based Reasoning 显示文摘 | Liu Changchun Shen Zhongqi Wu Like | 2012 | Journal of Ad- vanced Manufacturing Systems2012，11，2： | 1 |
| 10 | The advantages of penehyclidine hydrochloride over atropine in acute organophosphorus pesticide poisoning:A meta-analysis显示文摘Background:Penehyclidine hydrochloride(PHC)has been used for many years as an anticholinergic drug for the treatment of acute organophosphorus pesticide poisoning(AOPP).The purpose of this meta-analysis was to explore whether PHC has advantages over atropine in the use of anticholinergic drugs in AOPP.Methods:We searched Scopus,Embase,Cochrane,PubMed,ProQuest,Ovid,Web of Science,China Science and Technology Journal Database(VIP),Duxiu,Chinese Biomedical literature(CBM),WanFang,and Chinese National Knowledge Infrastructure(CNKI),from inception to March 2022.After all qualified randomized controlled trials(RCTs)were included,we conducted quality evaluation,data extraction,and statistical analysis.Statistics using risk ratios(RR),weighted mean difference(WMD),and standard mean difference(SMD).Results:Our meta-analysis included 20,797 subjects from 240 studies across 242 different hospitals in China.Compared with the atropine group,the PHC group showed decreased mortality rate(RR=0.20,95%confidence intervals[CI]:0.16–0.25,P<0.001),hospitalization time(WMD=-3.89,95%CI:-4.37 to-3.41,P<0.001),overall incidence rate of complications(RR=0.35,95%CI:0.28–0.43,P<0.001),overall incidence of adverse reactions(RR=0.19,95%CI:0.17–0.22,P<0.001),total symptom disappearance time(SMD=-2.13,95%CI:-2.35 to-1.90,P<0.001),time for cholinesterase activity to return to normal value 50–60%(SMD=-1.87,95%CI:-2.03 to-1.70,P<0.001),coma time(WMD=-5.57,95%CI:-7.20 to-3.95,P<0.001),and mechanical ventilation time(WMD=-2.16,95%CI:-2.79 to-1.53,P<0.001).Conclusion:PHC has several advantages over atropine as an anticholinergic drug in AOPP. | Siyao Zeng Lei Ma Lishan Yang Xiaodong Hu Cheng Wang Xinxin Guo Yi Li Yi Gou Yao Zhang Shengming Li Shaotong Zhang Xiaoxuan Wu Meihong Li Jing Lei Bingqian Li Chengfei Bi Like Ma Qingpeng Luo | 2023 | Journal of Intensive Medicine2023，3，2： | 0 |
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