|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Management of oligometastatic non-small cell lung cancer patients:Current controversies and future directions显示文摘Oligometastatic non-small cell lung cancer(NSCLC)describes an intermediate stage of NSCLC between localized and widely-disseminated disease.This stage of NSCLC is characterized by a limited number of metastases and a more indolent tumor biology.Currently,the management of oligometastatic NSCLC involves radical treatment(radiotherapy or surgery)that targets the metastatic lesions and the primary tumor to achieve disease control.This approach offers the potential to achieve prolonged survival in patients who,in the past,would have only received palliative measures.The optimal therapeutic strategies for the different scenarios of oligometastatic disease(intracranial vs extracranial disease,synchronous vs metachronous)remain undefined.Given the lack of head-to-head studies comparing radiotherapy to surgery in these patients,the decision to apply surgery or radiotherapy(with or without systemic treatment)must be based on prognostic factors that allow us to classify patients.This classification will allow us to select the most appropriate therapeutic strategy on an individualized basis.In the future,the molecular or microRNA profiles will likely improve the treatment selection process.The objective of the present article is to review the most relevant scientific evidence on the management of patients with oligometastatic NSCLC,focusing on the role of radiotherapy and surgery.We also discuss areas of controversy and future directions. | Felipe Counago Javier Luna Luis Leonardo Guerrero Blanca Vaquero María Cecilia Guillén-Sacoto Teresa González-Merino Begona Taboada Verónica Díaz Belén Rubio-Viqueira Ana Aurora Díaz-Gavela Francisco JoséMarcos Elia del Cerro | 2019 | World Journal of Clinical Oncology2019，10，10： | 5 |
| 2 | Effects of heavy metal concentrations (Cd, Zn and Pb) in agricultural soils near different emission sources on quality, accumulation and food safety in soybean [ Glycine max (L.) Merrill]显示文摘 | María Julieta Salazar Judith Hebelen Rodriguez Gastón Leonardo Nieto María Luisa Pignata | 2012 | Journal of Hazardous Materials2012，，： | 2 |
| 3 | Effects of nitrogen source,N∶P ratio and N-pulse concentration and frequency on the growth of Gracilaria cornea(Gracilariales,Rhodophyta) in culture显示文摘 | Leonardo N A Robledo D | 1999 | Hydrobiologia1999，，： | 1 |
| 4 | H igh-Ti and low-Ti mafic potassic magmas:key to plume-lithosphere interactions and continental flood-basah genesis显示文摘 | Gibson S A Thompson R N Leonardos O H | 1995 | Earth Planet Soi Lett1995，136，： | 1 |
| 5 | Esophagogastric junction outflow obstruction successfully treated with laparoscopic Heller myotomy and Dor fundoplication: First case report in the literature显示文摘BACKGROUND Esophagogastric junction outflow obstruction(EGJOO) is a rare syndrome,characterized by an elevation of the integrated relaxation pressure of the lower esophageal sphincter, not accompanied by alterations in esophageal motility that may lead to the criteria for achalasia. We were unable to find any prior report of the combination of Heller myotomy with anterior partial fundoplication(Dor) as the treatment for EGJOO. We herein report a case of EGJOO treated with laparoscopic Heller myotomy combined with Dor fundoplication.CASE SUMMARY A 26-year-old man presented with a 3-year history of solid dysphagia and a 30-kg weight loss. He was treated with oral nifedipine, isosorbide, and omeprazole,without resolution of symptoms. An upper gastrointestinal series(barium swallow) revealed a 'bird's beak' sign. Esophagogastroduodenoscopy was positive for Los Angeles grade A peptic esophagitis. High-resolution esophageal manometry was compatible with EGJOO. Esophageal pH monitoring showed pathological acid reflux both in orthostatic and decubitus position. An 8-cm laparoscopic Heller myotomy combined with an anterior 220° Dor fundoplication was performed. Solid diet was introduced on postoperative day 2, and the patient was discharged home the same day. At 17-mo follow-up, he reported no symptoms. Barium swallow was compatible with complete radiologic resolution.Both esophageal manometry and upper endoscopy showed normal findings 9 mo after the operation.CONCLUSION Surgical treatment with Heller myotomy and Dor fundoplication is a potential treatment option for EGJOO refractory to medical treatment. | Pedro F Pereira Andre RP Rosa Leonardo A Mesquita Marcelle J Anzolch Rafael N Branchi Augusto L Giongo Francisco C Paix?o Marcio F Chedid Cleber DP Kruel | 2019 | World Journal of Gastrointestinal Surgery2019，11，2： | 1 |
| 6 | Branding destinations versus branding hotels in a gaming destination-Examining the nature and significance of co-branding effects in the case study of Macao显示文摘 | LEONARDO A N SIU-IAN(AMY)SO | 2012 | International Journal of Hospitality Management2012，，31： | 1 |
| 7 | Real-time detection of PAH mixtures in the vapor phase at high temperatures显示文摘 | Leonardo R A Dimitra N S Brian M C | 2003 | Joumal of Analytical and Applied Pyrolysis2003，66，2： | 1 |
| 8 | Under- standing the Mediated Moderating Role of Customer Expectations in Customer Satisfaction Model: The Case of Casinos显示文摘 | Ip Kin Anthony Wong Leonardo A N Dioko | 2013 | Tourism Management2013，36，： | 1 |
| 9 | Polymerization of vinyl acetate in bulk and emulsion by gamma irradiation显示文摘 | ANDREA C M MANOEL N M LEONARDO G A | | 0，，71： | 1 |
| 10 | Central venous catheter-related infection in a prospective and observational study of 2,595 catheters显示文摘 | Leonardo Lorente Christophe Henry Marí a M Martí n | | 0，，： | 1 |
| 11 | Catheter-related infection in critically ill patients显示文摘 | Leonardo Lorente Jerusalen Villegas María M. Martín Alejandro Jiménez María L. Mora | 2004 | Intensive Care Medicine2004，，8： | 1 |
| 12 | Arterial catheter-related infection of 2,949 catheters显示文摘 | Leonardo Lorente Ruth Santacreu Marí a M Martí n | | 0，，： | 1 |
| 13 | The Late Cretaceous Impact of the Trindade Mantle Plume:Evidence from Large-volume, Mafic, Potassic Magmatism in SE Brazil 显示文摘 | GIBSON S A THOMPSON R N LEONARDOS O H | 1995 | Journal of Pe- trology1995，36，1： | 1 |
| 14 | Polymerization of vinyl acetate in bulk and emulsion by gamma irradiation显示文摘 | ANDREA C M MANOEL N M LEONARDO G A | 2004 | Radiation Physics and Chemistry2004，，71： | 1 |
| 15 | Effects of a nuclear power plant thermal discharge on habitat complexity and fish community structure in Ilha Grande Bay,Brazil显示文摘 | TATIANA P T LEONARDO M N FRANCISCO G A | 2009 | Marine Environmental Research2009，68，： | 1 |
| 16 | The Late Cretaceous impact of the Trindade mantle plume: evidence from large-volume, mafic, potassic magmatism in SE Brazil 显示文摘 | Gibson S A Thompson R N Leonardos O H | 1995 | Journal of Petrology1995，36，： | 1 |
| 17 | The Late Cretaceous impact of the Trindate mantle plume: Evidence from large-volume mafic potassic magmatism in SE Brazil 显示文摘 | Gibson S A Thompson R N Leonardos O H | 1995 | Journal of Petrology1995，36，： | 1 |
| 18 | Effects of nitrogen source, N : P ratio and N - pulse concentration and frequency on the growth of Gracilaria cornea (Gracilariales, Rhodophyta) in culture 显示文摘 | Leonardo N A Daniel R | 1999 | Hydrobiologia1999，，： | 1 |
| 19 | High-Ti and low-Ti mafic potassic magmas: Key to plume-lithosphere interactions and continental flood-basalt genesis显示文摘 | THOMPSON R N LEONARDOS O H | 1995 | Earth Planet Sci Lett1995，136，： | 1 |
| 20 | Under- standing the Mediated Moderating Role of Customer Expectations in Customer Satisfaction Model: The Case of casinos 显示文摘 | IpKin Anthony Wong Leonardo A N Dioko | 2013 | Tourism Management2013，36，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员