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| 1 | Portal vein thrombosis:Insight into physiopathology,diagnosis,and treatment显示文摘Portal vein thrombosis (PVT) is a relatively common complication in patients with liver cirrhosis, but might also occur in absence of an overt liver disease. Several causes, either local or systemic, might play an important role in PVT pathogenesis. Frequently, more than one risk factor could be identified; however, occasionally no single factor is discernable. Clinical examination, laboratory investigations, and imaging are helpful to provide a quick diagnosis, as prompt treatment might greatly affect a patient's outcome. In this review, we analyze the physiopathological mechanisms of PVT development, together with the hemodynamic and functional alterations related to this condition. Moreover, we describe the principal factors most frequently involved in PVT development and the recent knowledge concerning diagnostic and therapeutic procedures. Finally, we analyze the implications of PVT in the setting of liver transplantation and its possible influence on patients' future prognoses. | Francesca R Ponziani Maria A Zocco Chiara Campanale Emanuele Rinninella Annalisa Tortora Luca Di Maurizio Giuseppe Bombardieri Raimondo De Cristofaro Anna M De Gaetano Raffaele Landolfi Antonio Gasbarrini | 2010 | World Journal of Gastroenterology2010，16，2： | 75 |
| 2 | Effects of unfractionated and low molecular weight heparins on platdet thromboxane biosynthesis'in vivo'显示文摘 | De Candia E Rocca B | 1994 | Thromb Haetmost1994，72，6： | 1 |
| 3 | Efficiency and safety of low-dose as-pirin in polycythemia vera显示文摘 | Landolfi R Marchioli R Kutti J | 2004 | N EnglJ Med2004，350，2： | 1 |
| 4 | Pathophysiology of thrombosis in myeloproliferative neoplasms显示文摘 | Landolfi R Di Gennaro L | 2011 | Haematologica2011，96，： | 1 |
| 5 | Thrombin-induced platelet activation is inhibited by high-and low-molecular-weight heparin 显示文摘 | De Candia E De Cristofaro R Landolfi R | 1999 | Circulation1999，99，25： | 1 |
| 6 | Thrombin-induced platelet activation is inhibited by high and Low-molecular-weight heparin显示文摘 | CANANDIA E D CRISTOFARO R D LANDOLFI R | 1999 | Circulation1999，99，： | 1 |
| 7 | Efficacy and safety of low-dose aspirin in polycythemia vera 显示文摘 | Landolfi R Marchioli R Kutti J | 2004 | N Engl J Med2004，350，2： | 1 |
| 8 | Thrombin induced platelet activation is inhibited by high and low molecular weight heparin显示文摘 | De candia E De Cristofaro R Landolfi R | 1999 | Circulation1999，99，9： | 1 |
| 9 | Low-dose aspirin for the prevention of atherothrombosis 显示文摘 | Patrono C Garcia Rodriguez LA Landolfi R | 2005 | N Engl J Med2005，353，： | 1 |
| 10 | Vascular and neoplastic risk in a large cohort of patients with polycythemia vera显示文摘 | Marchioli R Finazzi G Landolfi R | 2005 | J Clin Oncol2005，23，： | 1 |
| 11 | Leukocytosis as a majorthrombotic risk factor in patients with polycythemia vcra显示文摘 | Landolfi R Di Gcnnaro L Barbui T | 2007 | Blood2007，109，6： | 1 |
| 12 | Vascular and neoplastic risk in a largecohort of patients with polycythemia vera显示文摘 | Marchioli R Finazzi G Landolfi R | 2005 | J Clin Oncol2005，23，10： | 1 |
| 13 | Efficiency and safety of low-dose aspirin in polycythemia vera显示文摘 | Landolfi R Marchioli R Kutti J | 2004 | N Engl J Med2004，305，2： | 1 |
| 14 | Low-dose aspirin for the prevention of atherothrombosis显示文摘 | Patrono C García Rodríguez LA Landolfi R | 2005 | N Engl J Med2005，353，22： | 1 |
| 15 | Low-dose aspirin for the prevention of atherothrombosis 显示文摘 | Patrono C Garela Rodriguez LA Landolfi R | 2005 | N Engl J Med2005，353，22： | 1 |
| 16 | Thrombin- induced platelet activation is inhibited by high - and low - molecular - weight heparin显示文摘 | De Candia E De Cristofaro R Landolfi R | 1999 | Circulation1999，99，25： | 1 |
| 17 | Pathophysiology of :hrombosis in myeloproliferative neoplasms显示文摘 | Landolfi R Di Gennaro L | 2011 | -Iaematologica2011，96，： | 1 |
| 18 | Thrombin - induced platelet activation is inhibited by high - and low - molecular- weight heparin 显示文摘 | De Cristofaro R Landolfi R | 1999 | Circulation1999，99，25： | 1 |
| 19 | Thrombosis in myeloproliferative and myelodysplastic syndromes显示文摘 | Landolfi R Di Gennaro L | 2012 | Hematology2012，17，： | 1 |
| 20 | Thrombin-induced platelet activation is inhibited by high and low-molecular-weight heparin 显示文摘 | Candia ED Cfitofaro RD Landolfi R | 1999 | Circulation1999，99，： | 1 |
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