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| 1 | Stem cells for cardiac repair: an introduction显示文摘Cardiovascular disease is a major cause of morbidity and mortality throughout the world. Most cardiovascular diseases, such as ischemic heart disease and cardiomyopathy, are associated with loss of functional cardiomyocytes. Unfortunately, the heart has a limited regenerative capacity and is not able to replace these cardiomyocytes once lost. In recent years, stem cells have been put forward as a potential source for cardiac regeneration. Pre-clinical studies that use stem cell-derived cardiac cells show promising results. The mechanisms,though, are not well understood, results have been variable, sometimes transient in the long term, and often without a mechanistic explanation.There are still severalmajor hurdles to be taken. Stem cell-derived cardiac cells should resemble original cardiac cell types and be able to integrate in the damaged heart. Integration requires administration of stem cell-derived cardiac cells at the right time using the right mode of delivery. Once delivered, transplanted cells need vascularization, electrophysiological coupling with the injured heart, and prevention of immunological rejection. Finally, stem cell therapy needs to be safe, reproducible, and affordable. In this review, we will give an introduction to the principles of stem cell based cardiac repair. | Bastiaan C du Pr(e) Pieter A Doevendans Linda W van Laake | 2013 | Journal of Geriatric Cardiology2013，10，2： | 2 |
| 2 | Complex regional pain syndrome type I (RSD): pathology of skeletal muscle and peripheral nerve显示文摘 | van der Laan L ter Laak H J Gabreels-Festen A | 1998 | Neurology1998，51，1： | 1 |
| 3 | Simplified Atmospheric Radiative Transfer Modeling for Estimating Incident PAR Using MODIS Atmosphere Products显示文摘 | Van Laake P E Sanchez-Azofeifa G A | 2004 | Remote Sensing of Environment2004，91，： | 1 |
| 4 | Estimation of soil sorption coeffi- cients of veterinary pharmaceuticals from soil properties 显示文摘 | Laak T L Gebbink W A Tolls J | 2006 | Environmental toxicology and chemistry2006，25，4： | 1 |
| 5 | The effect of pH and ionic strength on the sorption of sulfachloropyridazine, tylosin, and oxytet- racycline to soil 显示文摘 | Laak T L Gebbink W A Toils J | 2006 | Environmental toxicology and chemistry2006，25，4： | 1 |
| 6 | Centrifuge modeling of loose fill embankment subjected to uni-axial and bi-axial earthquakes显示文摘 | Ng C W W Li Xiang-Song Van Laak P A | 2004 | Soil Dynamics & Earthquake Engineering2004，，24： | 1 |
| 7 | MIBI ex- pression in basal cell layer: a diagnostic tool to identify premalig- nancies of the vulva显示文摘 | van der Avoort I A van der Laak J A Paffen A | 2007 | Mod Pathol2007，20，7： | 1 |
| 8 | Simplified atmospheric radiative transfer modelling for estimating incident PAR using MODIS atmosphere products显示文摘 | Sanchez-Azofeifa G A | 2004 | Remote Sensing of Environment2004，91，1： | 1 |
| 9 | Pretreatment vascular endothelial growth factor(VEGF)and matrix metalloproteinase- 9(MMP-9) serum levels in patients with metastatic non-small cell lung cancer(NSCLC)显示文摘 | Laak E Seheffler A Burkholder I | 2005 | Lung Cancer2005，50，1： | 1 |
| 10 | The Hong Kong Geotechnical Centrifuge and Its Unique Capabilities显示文摘 | NG C W W VAN LAAK P A TANG W H | 2001 | Sino-otechnics2001，83，： | 1 |
| 11 | Centrifuge modeling of loose fill embankment subjected to uni-axial and bi-axial earthquakes显示文摘 | NG C W W LI Xiang-song Van LAAK P A HOU Yu-jing | | 0，，04： | 1 |
| 12 | Outcome of four weeks' intervention with probiotics on symptom and endoscopic appearance after surgical reconstruction with a J-configurated ileal- pouch-anal-an astomosis in ulcerative colitis显示文摘 | Laake K 0 B jomek lettA A amodtG | 1980 | Gut1980，21，9： | 1 |
| 13 | Centrifuge modeling of loose fill embankment subjected to uni-axial and bi-axial earthquakes显示文摘 | NG C W W LI X S LAAK P A V | | Soil Dynamics and Earthq0，，： | 1 |
| 14 | Lone-term ex- cess mortality in 623 patients with brain atteriovenous malformations显示文摘 | Laak A Dashti R Seppgmen J el al | 2008 | Neurosurgery2008，63，2： | 1 |
| 15 | Functional status among elderly Norwegian fallers living at home显示文摘 | BERGLAND A PETTERSEN A M LAAKE K | 2000 | Physiother Res Int2000，5，： | 1 |
| 16 | Anthocyanins inhibit nuclear factor-kappaB activation in monocytes and reduce plasma concentrations of pro-inflammatory mediators in healthy adults显示文摘 | Karlsen A Retterstol L Laake P | | 0，，： | 1 |
| 17 | Alkaline Treatment of Template Containing Zeolites:Introducing Mesoporosity While Preserving Acidity显示文摘 | Van Laak Zhang Lei Parvulescu A | 2011 | Catal Today2011，168，1： | 1 |
| 18 | Anthocyanins inhibit nuclearfactor-B activation in monocytes and reduce plasmaconcentrations of pro-inflammatory mediators in healthyadults显示文摘 | Retterstol K A Laake L | 2007 | Journal of Nutrition2007，137，： | 1 |
| 19 | Alkaline treatment of template containing zeolites : introducing meso- porosity while preserving acidity 显示文摘 | Van Laak A N C Zhang L Parvulescu A N | 2011 | Catalysis Today2011，168，1： | 1 |
| 20 | Mesoporous mordenites obtained by sequential acid and alkaline treat- ments-catalysts for cumene production with enhanced accessibility 显示文摘 | Van Laak A N C Sagala S L Ze~evig J | 2010 | Journal of Catalysis2010，276，1： | 1 |
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