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| 1 | Cancer gene therapy targeting angiogenesis:An updated review显示文摘Since the relationship between angiogenesis and tumor growth was established by Folkman in 1971, scientists have made efforts exploring the possibilities in treating cancer by targeting angiogenesis. Inhibition of angiogenesis growth factors and administration of angiogenesis inhibitors are the basics of anti- angiogenesis therapy. Transfer of anti-angiogenesis genes has received attention recently not only because of the advancement of recombinant vectors, but also because of the localized and sustained expression of therapeutic gene product inside the tumor after gene transfer. This review provides the up-to-date information about the strategies and the vectors studied in the field of anti-angiogenesis cancer gene therapy. | Ching-Chiu Liu Zan Shen Hsiang-Fu Kung Marie CM Lin | 2006 | World Journal of Gastroenterology2006，12，43： | 4 |
| 2 | Association of telomere length with authentic pluripotency of ES/iPS cells显示文摘Telomerase 和 telomeres 为干细胞的不定的复制是重要的。最近,体的房间的 telomeres 被发现是 reprogrammed 在导致的 pluripotent 干细胞(iPSCs ) 伸长。然而,在在胚胎的干细胞(转换字符) 或 iPSCs 的 vivo 的发展 pluripotency 的 telomeres 的角色直接没被探讨。我们证明有长 telomeres 的转换字符展出真发展 pluripotency,由完全的转换字符小狗以及 germline 能干的怪物的产生证实了在啮齿类动物可得到的最紧的测试。有短 telomeres 的转换字符显示出减少的 teratoma 形成和怪物生产,并且没能产生完全的转换字符小狗。Telomere 长度高度被相关(r > 0.8 ) 与转换字符的发展 pluripotency。短 telomeres 减少 proliferative 率或转换字符的能力,改变与 telomere epigenetics 有关的基因的表示,为 embryogenesis 重要的下面调整基因并且破坏细菌房间区别。而且,有更长的 telomeres 的 iPSCs 与短 telomeres 比那些与更高的效率产生怪物。我们功能的 telomeres 为 ESCs/iPSCs 的发展 pluripotency 是必要的并且建议那 telomere 长度可以提供一个珍贵标记评估干细胞 pluripotency 的数据表演,特别地当紧测试不是可行的时。 | Junjiu Huang Fang Wang Maja Okuka Na Liu Guangzhen Ji Xiaoying Ye Bingfeng Zuo Minshu Li Ping Liang William W Ge John CM Tsibris David L Keefe Lin Liu | 2011 | Cell Research2011，21，5： | 3 |
| 3 | Update on endovascular therapies for cerebral vasospasm induced by aneurysmal subarachnoid hemorrhage显示文摘 | Liu JK Couldwell WT | 2006 | Neurosurg Focus2006，21，： | 1 |
| 4 | Hepatectomy for hepatocellular carcinoma: toward zero hospital deaths显示文摘 | Fan ST Lo CM Liu CL | 1999 | Ann Surg1999，229，3： | 1 |
| 5 | Sperm DNA fragmentation is increased in couples with unexplained recurrent pregnancy loss 显示文摘 | Carrell DT Liu L Peterson CM | 2003 | Arch Androl2003，49，1： | 1 |
| 6 | Maternal complications and perinatal outcomes associated with gestational hypertension and severe preeclampsia in Taiwanese women显示文摘 | Liu CM Cheng PJ Chang SD | 2008 | J Formos Med Assoc2008，107，： | 1 |
| 7 | Circulating intercellular adhesion molecule 1 ( ICAM-1 ) , E-selectin and vascular cell adhesion molecule 1 (VCAM-1) in head and neck cancer显示文摘 | Liu CM Sheen TS Ko JY | 1999 | Br J Cancer1999，79，2： | 1 |
| 8 | The role of small RNAs in human diseases: potential troublemaker and therapeutic tools 显示文摘 | Gong H Liu CM Liu DP | 2005 | Med Res Rev2005，25，3： | 1 |
| 9 | A randomized,controlled trial of postoperative adjuvant interferon therapy after resection of hepatocellular carcinoma显示文摘 | Lo CM Liu CL Chan SC | | 0，，06： | 1 |
| 10 | Puerarin protects the rat liver a- gainst oxidative stress -mediated DNA damage and apoptosis in- duced by lead 显示文摘 | Liu CM Ma JQ Sun YZ | 2012 | Exp Toxicol Pathol2012，64，： | 1 |
| 11 | Uptake and conversion of carbonyl sulfide in a lawn soil显示文摘 | Liu JF Mu YJ Geng CM | 2007 | Atmospheric Environment2007，41，： | 1 |
| 12 | Expression of matrix metalloproteinase-9 in human platelets:regulation of platelet activation in in vitro and vivo studies显示文摘 | Sheu JR Fong Th Liu CM | 2004 | Pharmacol2004，143，1： | 1 |
| 13 | Safety of duct-to-duct biliary reconstruction in right-lobe live-donor liver transplantation without biliary drainage显示文摘 | Liu CL Lo CM Chan SC | 2004 | Transplantation2004，77，5： | 1 |
| 14 | Choledochal cysts in adults 显示文摘 | Liu CL Fan ST Lo CM | 2002 | Arch Surg2002，137，4： | 1 |
| 15 | Mechanical strain modulates age-related changes in the pro-liferation and differentiation of mouse adipose-derived stromal cells显示文摘 | Huang SC Wu TC Yu HC Chen MR Liu CM Chiang WS Lin KM | | 0，，： | 1 |
| 16 | Early adult risk factor levels and subsequent coronary artery calcification: the CARDIA Study显示文摘 | Loria CM Liu K Lewis CE | 2007 | J Am Coil Cardiol2007，49，20： | 1 |
| 17 | New multifunctional melatonin- derived benzylpyridinium bromides with potent cholinergic, antioxidant, and neuroprotective properties as innovative drugs for Alzheimer's disease 显示文摘 | Luo XT Wang CM Liu Y | 2015 | Eur J Med Chem2015，103，： | 1 |
| 18 | Thermomechanics of the shape memory effect in polymers for biomedical applications 显示文摘 | Gall K Yakacki CM Liu Y | 2005 | J Biomed Mater Res A2005，73，3： | 1 |
| 19 | Technical refinement in adult-to-adult living donor liver transplantation using right lobe graft 显示文摘 | Fan ST Lo CM Liu CL | 2000 | AnnSurg2000，231，1： | 1 |
| 20 | Minimum graft size for successful living donor liver transplantation显示文摘 | Lo CM Fan ST Liu CL | 1999 | Transplantation1999，68，8： | 1 |
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