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| 1 | Dynamic dam-reservoir interaction analysis including effect of reservoir boundary absorption显示文摘Based on the scaled boundary finite-element method, the governing equations for the analysis of dam-reservoir interaction including the reservoir boundary absorption are developed. Coupling with the equation of dam-unbounded foundation interaction, it can effectively carry out the earthquake response analysis of dameservoir-foundation system. The proposed approach has the advantages that the effect of compressibility of reservoir water as well as the energy absorption of reservoir boundary on the earthquake response of arch dams and gravity dams can be efficiently evaluated and higher accuracy can be achieved. In comparison with the methods available in the literature, the computational cost can be reduced to a great extent. It facilitates the application of earthquake response analysis of dam-reservoir-foundation system including reservoir boundary absorption to the engineering practice. | LIN Gao DU JianGuo HU ZhiQiang | 2007 | Science China(Technological Sciences)2007，50，z1： | 23 |
| 2 | Cold adaptation in pigs depends on UCP3 in beige adipocytes显示文摘 | Jun Lin Chunwei Cao Cong Tao Rongcai Ye Meng Dong Qiantao Zheng Chao Wang Xiaoxiao Jiang Guosong Qin Changguo Yan Kui Li John R. Speakman Yanfang Wang Wanzhu Jin Jianguo Zhao | 2017 | Journal of Molecular Cell Biology2017，9，5： | 20 |
| 3 | The Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism显示文摘在动物农业和药的抗菌素的 overuse 引起了一系列潜在的威胁到公共健康。Macleaya cordata 是从 Papaveraceae 家庭的药用的植物种,提供为抗菌剂的制造的一个安全资源为家畜喂添加剂。从 M. 的活跃成分 ? cordata 被知道包括 benzylisoquinoline 碱(偏爱) 象 sanguinarine (圣) 和 chelerythrine (CHE ) 那样的 ?,而是他们的新陈代谢的小径还得在这非模型植物被学习。在 M. 的圣和 CHE 的活跃生合成 ? cordata 被喂 13标记 C 的酷氨酸。为了增加,推进卓见,我们 de novo 定序 M 的整个染色体。cordata,第一从 Papaveraceae 家庭被定序。M.? 盖住 378 Mb 的 cordata 染色体与 43.5%being 编码 22,328 预言的编码蛋白质的基因 transposable 元素。作为基础 eudicot 的一个成员, M.? cordata 染色体缺乏 ? 发生在几乎所有 eudicots 的 paleohexaploidy 事件。从 genomics 数据, 16 的一个完全的集合 ? 新陈代谢 ? 为圣和 CHE 生合成的基因被检索,并且 14 项他们的生物化学的活动被验证。这些 genomics 和新陈代谢的数据在 M. 显示出保存 BIA 新陈代谢的小径 ? cordata 并且由庄稼改进或微生物引起的小径重建为圣和 CHE 的未来生产提供知识基础。 | Xiubin Liu Yisong Liu Peng Huang Yongshuo Ma Zhixing Qing Qi Tang Huifen Cao Pi Cheng Yajie Zheng Zejun Yuan Yuan Zhou Jinfeng Liu Zhaoshan Tang Yixiu Zhuo Yancong Zhang Linlan Yu Jialu Huang Peng Yang Qiong Peng dinbo Zhang Wenkai Jiang Zhonghua Zhang Kui Lin Dae-Kyun Ro Xiaoya Chen Xingyao Xiong Yi Shang Sanwen Huang Jianguo Zeng | 2017 | Molecular Plant2017，10，7： | 19 |
| 4 | 空气质量模型及参数选用导则显示文摘本研究是为了在大气污染物浓度估算中提供一个可以接受的技术分析的共同尺度,将所需用的空气质量模式分为三个等级。第一级模式作为在制定大气环境管理的法规和政策时主要应用的模式。第二、三级模式作为研究级模式。本文详细介绍了第一级模式的主要应用原则,简要介绍了第二、三级模式。 | Lin Hong(Chinese Research Academy of Environmental Sciences, Beijing 100012)Sang Jianguo(Beijing University,Beijing 100871)Xu Dahai et al.(The Research Academy of Meteorology, Beijing 100086) | 1993 | 环境科学研究1993，6，4： | 18 |
| 5 | De novo mutation in ATP6V1B2 impairs lysosome acidification and causes dominant deafness-onychodystrophy syndrome显示文摘 | Yongyi Yuan Jianguo Zhang Qing Chang Jin Zeng Feng Xin Jianjun Wang Qingyan Zhu Jing Wu Jingqiao Lu Weiwei Guo Xukun Yan Hui Jiang Binfei Zhou Qi Li Xue Gao Huijun Yuan Shiming Yang Dongyi Han Zixu Mao Ping Chen Xi Lin Pu Dai | 2014 | Cell Research2014，24，11： | 13 |
| 6 | Dynamic mechanical behavior and the constitutive model of concrete subjected to impact loadings显示文摘Based on the theory of consecutive damage mechanics, micro-mechanics, statis-tics and the visco-plastic constitutive equation of Perzyna, a coupled model of damage and plasticity is developed to describe the complex behavior of concrete subjected to impact loadings. In this model, some suppositions about deformation of the material and evolution of the damage are made. First, concrete is macro-scopically assumed to be homogeneous and consecutive, while it is microscopi-cally filled with large amounts of micro-crack and micro-void defects. Second, the damage evolution of the micro-cracks is caused by the nucleation, growth and coalescence of the micro-cracks due to the interior tensile stress in concrete, which leads to a degradation in the strength and stiffness of concrete. Third, compaction of concrete is physically a collapse of the material micro-void. It pro-duces irreversible plastic strains in the material and, at the same time, an increase in the bulk modulus. Fourth, there is no interaction between the micro-crack and the micro-void. Last, when the damage reaches a critical value, the concrete may fail totally. The model parameters for concrete are determined by plate impact ex-periments. The model predictions fit the experimental results well. So the model can be used to simulate the dynamic mechanical behavior of concrete under impact loadings. | NING JianGuo LIU HaiFeng SHANG Lin | 2008 | Science China(Physics,Mechanics & Astronomy)2008，51，11： | 12 |
| 7 | Preventive effect of Shenkang injection against high glucose-induced senescence of renal tubular cells显示文摘Shenkang injection (SKI) is a classic prescription composed of Radix Astragali, rhubarb, Astragalus, Safflower, and Salvia. This treatment was approved by the State Food and Drug Administration of China in 1999 for treatment of chronic kidney diseases based on good efficacy and safety. This study aimed to investigate the protective effect of SKI against high glucose (HG)-induced renal tubular cell senescence and its underlying mechanism. Primary renal proximal tubule epithelial cells were cultured in (1) control medium (control group), medium containing 5 mmol/L glucose;(2) mannitol medium (mannitol group), medium containing 5 mmol/L glucose, and 25 mmol/L mannitol;(3) HG medium (HG group) containing 30 mmol/L glucose;(4) SKI treatment at high (200 mg/L), medium (100 mg/L), or low (50 mg/L) concentration in HG medium (HG+ SKI group);or (5) 200 mg/L SKI treatment in control medium (control+ SKI group) for 72 h. HG-induced senescent cells showed the emergence of senescence associated heterochromatin foci, up-regulation of P16INK4 and cyclin D1, increased senescence-associated β-galactosidase activity, and elevated expression of membrane decoy receptor 2. SKI treatment potently prevented these changes in a dose-independent manner. SKI treatment prevented HG-induced up-regulation of pro-senescence molecule mammalian target of rapamycin and p66Shc and down-regulation of anti-senescence molecules klotho, sirt1, and peroxisome proliferator-activated receptor-g in renal tubular epithelial cells. SKI may be a novel strategy for protecting against HG-induced renal tubular cell senescence in treatment of diabetic nephropathy. | Biqiong Fu Jie Yang Jia Chen Lirong Lin Kehong Chen Weiwei Zhang Jianguo Zhang Yani He | 2019 | Frontiers of Medicine2019，13，2： | 8 |
| 8 | Expert consensus on dental caries management显示文摘Dental Caries is a kind of chronic oral disease that greatly threaten human being’s health.Though dentists and researchers struggled for decades to combat this oral disease,the incidence and prevalence of dental caries remain quite high.Therefore,improving the disease management is a key issue for the whole population and life cycle management of dental caries.So clinical difficulty assessment system of caries prevention and management is established based on dental caries diagnosis and classification.Dentists should perform oral examination and establish dental records at each visit.When treatment plan is made on the base of caries risk assessment and carious lesion activity,we need to work out patient-centered and personalized treatment planning to regain oral microecological balance,to control caries progression and to restore the structure and function of the carious teeth.And the follow-up visits are made based on personalized caries management.This expert consensus mainly discusses caries risk assessment,caries treatment difficulty assessment and dental caries treatment plan,which are the most important parts of caries management in the whole life cycle. | Lei Cheng Lu Zhang Lin Yue Junqi Ling Mingwen Fan Deqin Yang Zhengwei Huang Yumei Niu Jianguo Liu Jin Zhao Yanhong Li Bin Guo Zhi Chen Xuedong Zhou | 2022 | International Journal of Oral Science2022，14，2： | 8 |
| 9 | Geological characteristics and tectonic signifcance of unconformities in Mesoproterozoic successions in the northern margin of the North China Block显示文摘Several stratigraphic breaks and unconformities exist in the Mesoproterozoic successions in the northern margin of the North China Block.Geologic characters and spatial distributions of fve of these unconformities,which have resulted from different geological processes,have been studied.The unconformity beneath the Dahongyu Formation is interpreted as a breakup unconformity,representing the time of transition from continental rift to passive continental margin.The unconformities beneath the Gaoyuzhuang and the Yangzhuang formations are considered to be the consequence of regional eustatic fuctuations,leading to the exposure of highlands in passive margins during low sea-level stands and transgressive deposition on coastal regions during high sea-level stands.The unconformity atop the Tieling Formation might be caused by uplift due to contractional deformation in a back-arc setting,whereas the uplift after the deposition of the Xiamaling Formation might be attributed to a continental collision event.It is assumed that the occurrences of these unconformities in the Mesoproterozoic successions in the northern margin of the North China Block had a close bearing on the assemblage and breakup of the Columbia and Rodinia supercontinents. | Yongqiang Qu Jianguo Pan Shouxian Ma Zhiping Lei Lin Li Guoli Wu | 2014 | Geoscience Frontiers2014，5，1： | 7 |
| 10 | Technology and application of pressure relief and permeability increase by jointly drilling and slotting coal显示文摘Difficulties with soft coal seams having a high gas content and high stress levels can be addressed by a technology of pressure relief and permeability increase.Slotting the seam by auxiliary drilling with a water jet that breaks the coal and slots the coal seam during the process of retreat drilling achieves pressure relief and permeability increase.Improved efficiency of gas extraction from a field test,high gas coal seam was observed.Investigating the theory of pressure relief and permeability increase required analyzing the characteristics of the double power slotting process and the effects of coal pressure relief and permeability increase.The influence of confining pressure on coal physical properties was examined by using FLAC3D software code to simulate changes of coal stress within the tool destruction area.The double power joint drilling method was modeled.Field experiments were performed and the effects are analyzed.This research shows that there is an ''islanding effect'' in front of the joint double power drill and slotting equipment.The failure strength of the coal seam is substantially reduced within the tool destruction area.Drilling depths are increased by 72% and the diameter of the borehole is increased by 30%.The amount of powdered coal extracted from the drill head increases by 17 times when using the new method.A 30 day total flow measurement from the double power drilled and slotted bores showed that gas extraction increased by 1.3 times compared to the standard drilled bores.Gas concentrations increased from 30% to 60% and were more stable so the overall extraction efficiency increased by a factor of two times. | Lin Baiquan Zhang Jianguo Shen Chunming Zhang Qizhi Sun Chen | 2012 | International Journal of Mining Science and Technology2012，22，4： | 7 |
| 11 | Paddy System with a Hybrid Rice Enhances Cyanobacteria Nostoc and Increases N2 Fixation显示文摘Biological nitrogen (N) fixation (BNF) plays a significant role in maintaining soil fertility in paddy field ecosystems. Rice variety influences BNF, but how different rice varieties regulate BNF and associated diazotroph communities has not been quantified. Airtight, field-based 15N2-labelling grow th chamber experiments were used to assess the BNF capac 辻 y of different rice varie ties. In addition, both the 16S rRNA and nifH genes were sequenced to assess the influence of different rice varieties on bacterial and diazotrophic communities in paddy soils. After subjecting a rice-soil system to 74 d of continuous airtight, field-based 15N2 labelling in pots in a growth chamber, the amounts of fixed N were 22.3 and 38.9 kg ha^-1 in inbred japonica (W23) and hybrid indica (IIY) rice cultivars plan ted in the rice-soil systems, respectively, and only 1%—2.5% of the fixed N was allocated to the rice plants and weeds. A greater abundance of diazotrophs was found in the surface soil (0-1 cm) under IIY than under W23. Sequencing of the 16S rRNA gene showed significantly greater abundances of the cyanobacterial genera Nostoc, Anabaena, and Cylindrospermum under IIY than under W23. Sequencing of the nifH gene also showed a significantly greater abundance of Nostoc under IIY than under W23. These results indicate that the hybrid rice cultivar (IIY) promoted BNF to a greater extent than the inbred rice cultivar (W23) and that the increase in BNF might have been due to the enhanced heterocystous cyanobacteria Nostoc. | MA Jing BEI Qicheng WANG Xiaojie LIU Gang Georg CADISCH LIN Xingwu ZHU Jianguo SUN Xiaoli XIE Zubin | 2019 | Pedosphere2019，29，3： | 7 |
| 12 | Potassium Uptake and Transport in Apple Roots Under Drought Stress显示文摘As one of the most important mineral nutrient elements, potassium(K^+) plays an important role in many plant physiological processes and determines both the yield and quality of crops. There are two typical gene families that regulate K^+transport in higher plants, including K^+channels and K^+transporters. However, little is known about how these channels and transporters divide their work in response to drought stress. In this study, the hydroponic experiment was conducted on Malus hupehensis. The K^+content was found to decrease in response to drought stress in M. hupehensis, the aboveground decreased by 34.15% and the underground decreased by 3.97%. Meanwhile, the root morphology change was detected by scanning the root system. Under conditions of drought, the genes encoding K^+transporters were upregulated including MdCHX1.3, MdCHX4.11, MdCHX4.8, MdCHX4.9, Md HKT1, and MdHAK3.2. The net influx of K^+was inhibited by 19.47% with the action of K^+channel inhibitors(CsCl), however a significant decrease(80.99%; P < 0.05) was found in roots exposed to a PM H+-ATPase(orthovanadate) inhibitor by utilizing a non-invasive micro-test technique. The trend of H+efflux was similar to that of K^+. The data suggested that the positive influx of K^+through the transporter accounted for the main K^+uptake under drought stress. These results suggest that we can improve the uptake of K^+by purposely up-regulating specific K^+transporters under drought stress. This process may improve growth, yield, quality, and stress tolerance in apple trees. | Jianguo Qi Simin Sun Lin Yang Mingjun Li Fengwang Ma Yangjun Zou | 2019 | Horticultural Plant Journal2019，5，1： | 6 |
| 13 | Preparation and biodistribution of ^(99)Tc^m-PIDP as bone imaging agent显示文摘A novel zoledronic acid derivative,1-hydroxy-2-(2-propyl-1H-imidazol-1-yl)ethane-1,1-diyldiphosphonic acid (PIDP), was synthesized by three-step reactions from 2-propyl-1H-imidazole. It was labeled with 99Tcm in conditions of 0.1 mg SnCl2.2H2O at pH 6.0 and 99TcmO4? in aqueous solution for 20 min at room temperature. The labeling yield and radiochemical purity of 99Tcm-PIDP are both higher than 95%. The biodistribution results show that the bone uptake is up to 8.47% ID/g which is the maximum of bone uptake at 30 min after injection of 99Tcm-PIDP in mice. The pharmacokinetic parameters can be estimated from the exponential equation of C=59.565e-11.307t+2.069e-1.211t. The clear bone image of rabbit was obtained at 120 min after injection of 99Tcm-PIDP. The results indicate that 99Tcm-PIDP has highly selective uptake in the skeletal and low uptake, rapid clearance in soft tissues, so it would be a potential novel bone imaging agent. | CHEN Chuanqing LUO Shineng LIN Jianguo YANG Min YE Wanzhong QIU Ling SANG Guangming XIA Yongmei | 2009 | Nuclear Science and Techniques2009，20，5： | 6 |
| 14 | A draft sequence of the rice (Oryza sativa ssp. indica) genome显示文摘The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a 'whole genome shotgun' approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in China and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2214.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.29% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software package | YU Jun, HU Songnian, WANG Jun,LI Songgang WONG Ka-Shu Gane, LIU Bin,DENG Yajun, DAI Li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, LIU Jing,SUN Jiandong , TANG Jiabin, CHEN Yanjiong,HUANG Xiaobing, LIN Wei, YE Chen, TONG Wei,CONG Lijuan, GENG Jianing, HAN Yujun, LI Lin,LI Wei, HU Guangqiang, HUANG Xiangang,LI Wenjie, LI Jian, LIU Zhanwei, LI Long,LIU Jianping, Ql Qiuhui, LIU Jinsong, LI Li,WANG Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, DONG Wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,LI Xianran, WANG Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, DONG Jianhai, ZENG Wanyong,TAO Lin, CHEN Xuewei, HE Jun, LIU Daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,LI Gang, GAO Hui, LI Ping, CHEN Wei ,WANG Xudong, ZHANG Yong, HU Jianfei,WANG Jing, LIU Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, LI Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN Runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,LI Guojie, LIU Siqi, HUANG Guyang,TAO Ming, WANG Jian, ZHU Lihuang,YUAN Longping& YANG HuanmingBeijing Genomics Institute/Center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, China Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China National Hybrid Rice R & D Center, Changsha 410125, China Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China College of Life Sciences, Peking University, Beijing 100871, China Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, China Digital China Ltd., Beijing 100080, China Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100080, China Medical College, Xi’an Jiaotong University, Xi’an 710061, ChinaThese authors contributed equally to this work.Corresponding author.Corresponden | 2001 | Chinese Science Bulletin2001，46，23： | 6 |
| 15 | Effects of Different Biochars on Pinus elliottii Growth,N Use Efficiency,Soil N_2O and CH_4 Emissions and C Storage in a Subtropical Area of China显示文摘Intensive management of planted forests may result in soil degradation and decline in timber yield with successive rotations.Biochars may be beneficial for plant production, nutrient uptake and greenhouse gas mitigation. Biochar properties vary widely and are known to be highly dependent on feedstocks, but their effects on planted forest ecosystem are elusive. This study investigated the effects of chicken manure biochar, sawdust biochar and their feedstocks on 2-year-old Pinus elliottii growth, fertilizer N use efficiency(NUE), soil N_2O and CH_4 emissions, and C storage in an acidic forest soil in a subtropical area of China for one year. The soil was mixed with materials in a total of 8 treatments: non-amended control(CK); sawdust at 2.16 kg m-^(2)(SD); chicken manure at 1.26 kg m-^(2)(CM); sawdust biochar at 2.4 kg m-^(2)(SDB); chicken manure biochar at 2.4 kg m-^(2)(CMB);^(15)N-fertilizer alone(10.23 atom%^(15)N)(NF); sawdust biochar at 2.4 kg m-^(2)plus15N-fertilizer(SDBN) and chicken manure biochar at 2.4 kg m-^(2)plus15N-fertilizer(CMBN). Results showed that the CMB treatment increased P. elliottii net primary production(aboveground biomass plus litterfall)and annual net C fixation(ANCF) by about 180% and 157%, respectively, while the the SDB treatment had little effect on P. elliottii growth. The15 N stable isotope labelling technique revealed that fertilizer NUE was 22.7% in CK, 25.5% in the NF treatment, and37.0% in the CMB treatment. Chicken manure biochar significantly increased soil p H, total N, total P, total K, available P and available K. Only 2% of the N in chicken manure biochar was available to the tree. The soil N_2O emission and CH_4 uptake showed no significant differences among the treatments. The apparent C losses from the SD and CM treatments were 35% and 61%, respectively;while those from the CMB and SDB treatments were negligible. These demonstrated that it is crucial to consider biochar properties while evaluating their effects on plant growth and C sequestration. | LIN Zhibin LIU Qi LIU Gang Annette L.COWIE BEI Qicheng LIU Benjuan WANG Xiaojie MA Jing ZHU Jianguo XIE Zubin | 2017 | Pedosphere2017，27，2： | 6 |
| 16 | Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis显示文摘 | Lin He Xinhua Liu Jianguo Yang Wanjin Li Shumeng Liu Xujun Liu Ziran Yang Jie Ren Yue Wang Lin Shan Chengjian Guan Fei Pei Liandi Lei Yu Zhang Xia Yi Xiaohan Yang Jing Liang Rong Liu Luyang Sun Yongfeng Shang | 2018 | Cell Research2018，28，9： | 5 |
| 17 | De novo assembly of a new Olea europaea genome accession using nano pore seque ncing显示文摘Olive(Olea europaea L.)is internationally renowned for its high-end product,extra virgin olive oil.An incomplete genome of O.europaea was previously obtained using shotgun sequencing in 2016.To further explore the genetic and breeding utilization of olive,an updated draft genome of olive was obtained using Oxford Nanopore third-generation sequencing and Hi-C technology.Seven different assembly strategies were used to assemble the fi nal genome of 1.30 Gb,with contig and scaffold N50 sizes of4.67 Mb and 42.60 Mb,respectively.This greatly increased the quality of the olive genome.We assembled 1.1 Gb of sequences of the total olive genome to 23 pseudochromosomes by Hi-C,and 53,518 protein-coding genes were predicted in the current assembly.Comparative genomics analyses,including gene family expansion and contraction,whole-genome replication,phylogenetic analysis,and positive selection,were performed.Based on the obtained high-quality olive genome,a total of nine gene families with 202 genes were identi fi ed in the oleuropein biosynthesis pathway,which is twice the number ofgenes identi fi ed from the previous data.This new accession of the olive genome is of suf fi cient quality for genome-wide studies on gene function in olive and has provided a foundation for the molecular breeding of olive species. | Guodong Rao Jianguo Zhang Xiaoxia Liu Chunfu Lin Huaigen Xin Li Xue Chenhe Wang | 2021 | Horticulture Research2021，8，1： | 4 |
| 18 | Crystal Plasticity Finite Element Process Modeling for Hydro-forming Micro-tubular Components显示文摘Micro-tubes manufactured by hydro-forming techniques have now been widely used in medical and microelectronics applica- tions. One of the difficulties in forming such parts is the control of localized necking in the initial stages of the deformation/forming process. A lack of microstructural information causes conventional macro-mechanics finite element(FE) tools to break down when used to investigate the localized microstructure evolution and necking encountered in micro-forming. An effort has been made to create an integrated crystal plasticity finite element(CPFE) system that enables micro-forming process simulations to be carried out easily, with the important features in forming micro-parts captured by the model. Based on Voronoi tessellation and probability theory, a virtual GRAIN(VGRAIN) system is created for generating grains and grain boundaries for micro-materials. Numerical procedures are devel- oped to link the physical parameters of a material to the control variables in a Gamma distribution. A script interface is developed so that the virtual microstructure can be input to the commercial FE code, ABAQUS, for mesh generation. A simplified plane strain CPFE modeling technique is developed and used to capture localized thinning and failure features for hydro-forming of micro-tubes. Grains within the tube workpiece, their distributions and orientations are generated automatically by using the VGRAIN system. A set of crystal viscoplasticity constitutive equations are implemented in ABAQUS/Explicit by using the user-defined material subroutine, VUMAT. Lo- calized thinning is analyzed for different microstructures and deformation conditions of the material using the CPFE modeling technique. The research results show that locations of thinning in forming micro-tubes can be random, which are related to microstructure and grain orientations of the material. The proposed CPFE technique can be used to predict the locations of thinning in forming micro-tubes. | ZHUANG Weimin WANG Shiwen BALINT Daniel LIN Jianguo | 2011 | Chinese Journal of Mechanical Engineering2011，24，1： | 4 |
| 19 | Syntheses of haptens and hapten-protein conjugates for insecticide propoxur and cyhalothrin显示文摘A facile procedure was described for the hapten design of the N-methylcarbamate insecticide propoxur.Two new haptens of propoxur(hapten 1a and hapten 1b) were synthesized by introducing appropriate spacers in the pesticide aromatic moiety of the analyte molecular structure.First,the propoxur reacted with nitric acid to yield the intermediate product.Then hapten 1a was prepared via the reduction of the intermediate product,and hapten 1b was formed by the acylation of hapten 1a with succinic anhydride.In addition,we have also developed a simple method to prepare hapten 2 for the pyrethroid insecticide cyhalothrin,which only requires two steps including the reactions of nitration and reduction.Three haptens were coupled to carrier proteins to prepare the corresponding artificial antigens.The molecular structures of these three haptens were identified by 1H NMR and MS,and those of the artificial antigens were confirmed by UV-vis. | Sang, GuangMing Luo, ShiNeng Lin, JianGuo Qiu, Ling Chen, ChuanQing Yang, HaiLin Xia, YongMei | 2010 | Science China Chemistry2010，53，5： | 3 |
| 20 | An improved noise reduction transformation for algorithm based on wavelet MEMS gyroscope显示文摘 | Jianguo YUAN Yantao YUAN Feilong LIU Yu PANG Jinzhao LIN | 2015 | Frontiers of Optoelectronics2015，8，4： | 3 |
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