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| 1 | Effect of nitrification inhibitor DMPP on nitrogen leaching, nitrifying organisms, and enzyme activities in a rice-oilseed rape cropping system显示文摘DMPP (3,4-dimethylpyrazole 磷酸盐) 被用来从沥滤或脱氮减少氮(N) 损失并且在农业土地改进 N 供应。然而,它使涉及 N 的有机体和酶活动硝化骑车的土壤上的影响大部分是未知的。因此,为二年,一个在农场上实验被进行了,到阐明矿物质 N 上的 DMPP 的效果(NH4+- N 和 NO3 ? 在 rice-oilseed 的沥滤的 -N) ,使硝化的有机体,和从的酶强奸收割系统。独自包括脲的三个处理(UA ) ,脲 +1% DMPP (DP ) ,和没有化肥(CK ) ,被执行了。结果证明那 DP 提高了吝啬的 NH4+-N 集中由 19.1%24.3% ,但是减少了吝啬的 NO3 ?-N 集中由 44.9%56.6% 在 leach 吃了在二年的大米强奸旋转下面,与 UA 处理相比。氧化的氨的人口细菌,硝酸盐还原酶的活动,和在 DP 处理的亚硝酸根 reductase 减少了大约 24.5%30.9% , 14.9%43.5% ,和 14.7%31.6% ,分别地作为与 UA 处理相比。然而,亚硝酸根氧化细菌和氢氧根胺 reductase 由 DMPP 仍然保持几乎未受影响。DMPP 有潜力也减少 NO3,这被建议 ?-N 由从脱氮禁止氨氧化或 N 损失沥滤,它赞成在 rice-oilseed 的 N 谈话强奸收割系统。 | LI Hua LIANG Xinqiang CHEN Yingxu LIAN Yanfeng TIAN Guangming NI Wuzhong | 2008 | Journal of Environmental Sciences2008，20，2： | 27 |
| 2 | Dry reforming of methane on active and coke resistant Ni/Y_2Zr_2O_7 catalysts treated by dielectric barrier discharge plasma显示文摘In this study, Ni/Y_2Zr_2O_7 catalysts prepared with impregnation method and treated by dielectric barrier discharge plasma(DBD) in different atmospheres have been investigated for methane dry reforming. It is revealed by H_2-TPR that plasma treatment can enhance the interaction between Ni O/Ni particles and the Y_2Zr_2O_7 pyrochlore support. Therefore, catalysts with smaller Ni O and Ni grains sizes, higher metallic Ni active surface areas can be achieved, as evidenced by XRD, TEM and H_2 adsorption-desorption measurements. As a consequence, the plasma-treated catalysts show significantly improved activity, stability and coke resistance, as testified by the TEM and TGA-DSC results. Plasma treatment in H_2/Ar gas mixture is found to be the best condition to prepare Ni/Y_2Zr_2O_7, which can be used to obtain a catalyst with the highest activity, stability and most potent coke resistance. It is believed that the smaller Ni grain size and higher metallic Ni active surface area induced by plasma treatment are the inherent reasons accounting for the promoted reaction performance of the Ni/Y_2Zr_2O_7 pyrochlore catalysts. | Xiuzhong Fang Jie Lian Kaiwen Nie Xianhua Zhang Yanfeng Dai Xianglan Xu Xiang Wang Wenming Liu Changqing Li Wufeng Zhou | 2016 | Journal of Energy Chemistry2016，25，5： | 3 |
| 3 | PIPSKI is required for cardiovascular andneuronal development显示文摘 | Yanfeng Wang Lurong Lian Jeffrey A Golden | 2007 | Proe Natl Aead Sei U S A2007，104，11： | 1 |
| 4 | Lynch syndrome pre-screening and comprehensive characterization in a multi-center large cohort of Chinese patients with colorectal cancer显示文摘Objective:Lynch syndrome(LS)pre-screening methods remain under-investigated in colorectal cancers(CRCs)in Asia.Here,we aimed to systematically investigate LS pre-screening and comprehensively characterize LS CRCs.Methods:Microsatellite instability(MSI)and germline variants of DNA mismatch repair(MMR)genes were examined in 406 deficient MMR(dMMR)and 250 proficient MMR CRCs.The genetic differences between LS and sporadic CRCs were studied with whole exome sequencing analysis.Results:The incidence of dMMR in Chinese patients with CRCs was 13.8%.Consistency analysis between MMR immunohistochemistry(IHC)and MSI testing showed the kappa value was 0.758.With next-generation sequencing(NGS),germline variants were detected in 154 CRCs.Finally,88 patients with CRC were identified as having LS by Sanger sequencing.Among them,we discovered 21 previously unreported pathogenic germline variants of MMR genes.Chinese patients with LS,compared with sporadic CRCs,tended to be early-onset,right-sided,early-stage and mucinous.Overall,the performance of MMR IHC and MSI testing for LS pre-screening was comparable:the area under the ROC curve for dMMR,MSI-H,and MSI-H/L was 0.725,0.750,and 0.745,respectively.dMMR_MSI-H LS and sporadic CRCs showed substantial differences in somatic genetic characteristics,including different variant frequencies of APC,CREBBP,and KRAS,as well as different enriched pathways of VEGF,Notch,TGFβR,mTOR,ErbB,and Rac protein signal transduction.Conclusions:MMR IHC and MSI testing were effective methods for LS pre-screening.The revealed clinical and somatic genetic characteristics in LS CRCs may have the potential to improve the performance of LS pre-screening in combination with dMMR/MSI. | Yan Li Lihong Fan Jianming Zheng Xiu Nie Yu Sun Qin Feng Shenyi Lian Wenqi Bai Weijing Cai Yanan Yang Bo Su Yanfeng Xi Dongmei Lin | 2022 | Cancer Biology & Medicine2022，19，8： | 0 |
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