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| 1 | The Chrysanthemum nankingense Genome Provides Insights into the Evolution and Diversification of Chrysanthemum Flowers and Medicinal Traits显示文摘The Asteraceae (Compositae),a large plant family of approximately 24 000-35 000 species,accounts for^10% of all angiosperm species and contributes a lot to plant diversity.The most representative members of the Asteraceae are the economically important chrysanthemums (Chrysanthemum L.)that diversified through reticulate evolution.Biodiversity is typically created by multiple evolutionary mechanisms such as wholegenome duplication 0NGD)or polyploidization and locally repetitive genome expansion.However,the lack of genomic data from chrysanthemum species has prevented an in-depth analysis of the evolutionary mechanisms involved in their diversification.Here,we used Oxford Nanopore long-read technologyto sequence the diploid Chrysanthemum nankingense genome,which represents one of the progenitor genomes of domesticated chrysanthemums.Our analysis revealed that the evolution of the C.nankingense genome was driven by bursts of repetitive element expansion and WGD events including a recentWGD that distinguishes chrysanthemum from sunflower,which diverged from chrysanthemum approximately 38.8 million years ago.Variations of ornamental and medicinal traits in chrysanthemums are linked to the expansion of candidate gene families by duplication events including paralogous gene duplication.Collectively,our study of the assembled reference genome offers new knowledge and resources to dissect the history and pattern of evolution and diversification of chrysanthemum plants,and also to accelerate their breeding and improvement. | Chi Song Yifei Liu Aiping Song Gangqiang Dong Hongbo Zhao Wei Sun Shyam Ramakrishnan Ying Wang Shuaibin Wang Tingzhao Li Yan Niu Jiafu Jiang Bin Dong Ye Xia Sumei Chen Zhigang Hu Fadi Chen Shilin Chen | 2018 | Molecular Plant2018，11，12： | 24 |
| 2 | Advances and problems in hydrocarbon exploration in the Tazhong area, Tarim Basin显示文摘Located in the middle of the Tarim Basin, Tazhong is a typical area of compound reservoirs rich in oil and gas found in the Carboniferous, Silurian and Ordovician strata. The proved, probable and possible reserves (3P reserves) in the area amount to 5×108 tons, so it is of great significance to study the advances and problems in hydrocarbon exploration in the Tazhong area. On the basis of exploration history and analysis of scientific problems, we outline eight achievements: distribution characteristics of reservoirs, stages of reservoir formation, different sources of oil and gas and their respective contributions, the effective regional caprock and reservoir-caprock combinations dominating the vertical distribution of hydrocarbon reservoirs, the control of the Tazhong Palaeo-uplift on reservoir formation and establishing geologic models, structure balance belts influencing the reconstruction and residual potential of reservoirs after accumulation, the rules and mechanisms of fractures controlling oil and gas, and the types of favorable reservoirs and their characteristics of controlling oil and gas distribution. We further point out the main problems about the oil and gas exploration in the Tazhong area and put forward some relevant proposals. | Zhou Xinyuan Pang Xiongqi Li Qiming Pang Hong Xiang Caifu Jiang Zhenxne Li Sumei Liu Luofu | 2010 | Petroleum Science2010，7，2： | 12 |
| 3 | Main progress and problems in research on Ordovician hydrocarbon accumulation in the Tarim Basin显示文摘The Tarim Basin is the largest petroliferous basin in the northwest of China, and is composed of a Paleozoic marine craton basin and a Meso-Cenozoic continental foreland basin. It is of great significance in exploration of Ordovician. In over 50 years of exploration, oil and gas totaling over 1.6 billion tonnes oil-equivalent has been discovered in the Ordovician carbonate formation. The accumulation mechanisms and distribution rules are quite complicated because of the burial depth more than 3,500 m, multi-source, and multi-stage accumulation, adjustment, reconstruction and re-enrichment in Ordovician. In this paper, we summarized four major advances in the hydrocarbon accumulation mechanisms of Ordovician carbonate reservoirs. First, oil came from Cambrian and Ordovician source rocks separately and as a mixture, while natural gas was mainly cracked gas generated from the Cambrian-Lower Ordovician crude oil. Second, most hydrocarbon migrated along unconformities and faults, with different directions in different regions. Third, hydrocarbon migration and accumulation had four periods: Caledonian, early Hercynian, late Hercynian and Himalayan, and the latter two were the most important for oil and gas exploration. Fourth, hydrocarbon accumulation and evolution can be generally divided into four stages: Caledonian (the period of hydrocarbon accumulation), early Hercynian (the period of destruction), late Hercynian (the period of hydrocarbon reconstruction and re-accumulation), and Himalayan (the period of hydrocarbon adjustment and re-accumulation). Source rocks (S), combinations of reservoir-seal (C), paleo-uplifts (M), structure balance belt (B) matched in the same time (T) control the hydrocarbon accumulation and distribution in the Ordovician formations. Reservoir adjustment and reconstruction can be classified into two modes of physical adjustment and variation of chemical compositions and five mechanisms. These mechanisms are occurrence displacement, biodegradation, multi-source mixing, high-temperature cracking and late gas invasion. Late hydrocarbon accumulation effects controlled the distribution of current hydrocarbon. The T-BCMS model is a basic geological model to help understanding the control of reservoirs. At present, the main problems of hydrocarbon accumulation focus on two aspects, dynamic mechanisms of hydrocarbon accumulation and the quantitative models of oil-bearing in traps, which need further systemic research. | Pang Xiongqi Tian Jun Pang Hong Xiang Caifu Jiang Zhenxue Li Sumei | 2010 | Petroleum Science2010，7，2： | 10 |
| 4 | Oil-source rock correlation and quantitative assessment of Ordovician mixed oils in the Tazhong Uplift, Tarim Basin显示文摘The origin of the marine oils in the Tarim Basin has long been a disputed topic. A total of 58 DST (drill stem test) crude oil and 8 rock samples were investigated using a comprehensive geochemical method to characterize and identify the origin of the Ordovician oils in the Tazhong Uplift, Tarim Basin, northwest China. Detailed oil–oil and oil–source rock correlations show that the majority of the oils have typical biomarker characteristics of the Middle-Upper Ordovician (O2+3) source rock and the related crude oil. These characteristics include a distinct 'V-shaped' relative abundance of C27, C28 and C29 regular steranes, low abundance of dinosterane, 24-norcholestanes, triaromatic dinosteroids and gammacerane. Only a few oils display typical biomarker characteristics indicating the Cambrian–Lower Ordovician (∈-O1) genetic affinity, such as linear or anti 'L' shape distribution of C27, C28 and C29 regular sterane, with relatively high concentrations of dinosterane, 24-norcholestanes, triaromatic dinosteroids and gammacerane. It appears that most of the Ordovician oils in the Tazhong Uplift were derived from the O2+3 intervals, as suggested by previous studies. However, the compound specific n-alkane stable carbon isotope data indicate that the Ordovician oils are mixtures from both the ∈-O1 and O2+3 source rocks rather than from the O2+3 strata alone. It was calculated that the proportion of the∈-O1 genetic affinity oils mixed is about 10.8%-74.1%, with an increasing trend with increasing burial depth. This new oil-mixing model is critical for understanding hydrocarbon generation and accumulation mechanisms in the region, and may have important implications for further hydrocarbon exploration in the Tarim Basin. | Li Sumei Pang Xiongqi Zhang Baoshou Xiao Zhongyao Gu Qiaoyuan | 2010 | Petroleum Science2010，7，2： | 10 |
| 5 | Origin of the unusually high dibenzothiophene concentrations in Lower Ordovician oils from the Tazhong Uplift,Tarim Basin,China显示文摘The origin of the unusually high dibenzothiophene (DBT) concentrations in Lower Ordovician oils from the Tazhong Uplift,Tarim Basin was studied by Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS).The most abundant sulfur compounds in the oils are S 1 species with doublebond equivalent (DBE) values of 1-19 and 11-48 carbon atoms.The range of the number of carbon atoms in the sulfur compounds detected by the FT-ICR MS (S 1 species with DBE=9) is about ten times larger than that for sulfur compounds detected by GC/MS (DBTs).This suggests that FT-ICR MS is a much better approach than GC/MS for characterization of DBTs in crude oils.The abundance of S 1 species with DBE=1-8 decreased with increasing thermal maturity,while the abundance of S 1 species with DBE=9 (primarily DBTs) increased.Therefore,thermal maturity is an important factor in the formation of oils with high DBT concentrations.Unusually high abundances of S 1 species with low DBE values (1-8),which include sulfide,thiophene and benzothiophene,were observed in several oils,especially the TZ83 (O 1) oil with high or very high thermal maturity.Thermochemical sulfate reduction (TSR) was thought to be the reason for the high abundance of these low DBE compounds in deep reservoirs,and thermochemical sulfate reduction could affect the distribution and composition of DBTs in the oils.According to the results of FT-ICR MS analysis,there are no signs that TSR is occurring or has occurred recently for most of the Lower Ordovician oils. | Li Sumei Pang Xiongqi Shi Quan Zhang Baoshou Zhang Haizu Pan Na Zhao Ming | 2011 | Petroleum Science2011，8，4： | 9 |
| 6 | Microscopic energy transport through photon-electron-phonon interactions during ultrashort laser ablation of wide bandgap materials Part Ⅰ: photon absorption显示文摘The new phenomena induced by femtosecond lasers lead to the new area of ultrafast science.It is a significantchallenge to explain the phenomena associated with complex non-equilibrium and non-linear processes.Althoughthere is a growing body of experimental observation,a comprehensive model remains undeveloped.We reviewthe challenges in understanding the photon absorption stage mainly for the femtosecond ablation of wide bandgap materialsat the intensities of 10^(13)~10^(14) W/cm^2.Major opinions and challenges in ionization mechanisms are presentedby primarily considering multiphoton ionization and avalanche ionization. | Lan Jiang Lishan Li Sumei Wang Hai-Lung Tsai | 2009 | 中国激光2009，36，4： | 6 |
| 7 | Origin of the Silurian Crude Oils and Reservoir Formation Characteristics in the Tazhong Uplift显示文摘在 Tazhong 的志留纪阶层高举因为它保存从多级式的构造进化生产的烃的一些特征,是为探索的一根重要地平线。为这个原因,志留纪油和他们的形成特征的起源的学习在在 Tazhong 区域为合成的烃累积地区揭示机制组成主要部分。Geochemical 调查显示在 Tazhong 的志留纪油的物理性质与带和块变化,即,当正常、轻时,重油在在北方斜坡堵住得好的 TZ4715 被散布油在没有。我指责带和 TZ16 堵住得好,它意味着油性质被结构的模式控制。在志留纪油的大多数 biomarkers 类似于中间上面的奥陶纪来源岩石的,建议一种好基因关系。然而,在油和这些油被混合,这上油的在包括显示的液体的烃的化学部件的 n 链烷的复合特定的同位素源于奥陶纪来源摇的中间上面的奥陶纪和 CambrianLower。大多数志留纪油有象更早的 biodegradation 一样的第二等的改变的一个记录,包括在全部的离子水流( TIC )的 UCM 驼峰的出现色层谱浸透并且在原油的浸透的烃的芳香的烃和 25-norhopane ,并且在许多光和重部件从的常规变化结构对结构的高度低。志留纪上油的事实在链链烷被充实,例如, n 链烷和 25-norhopane,建议他们是有以后正常的油的更早降级的油的混合的油。志留纪油经历了在液体包括根据作文和分发以及水库的成熟控告原油和油的石油的至少三个事件,这被建议。在 TZ4715 的这些油的迁居和累积模型堵住得好,没有。我指责带和 TZ16 堵住得好与,但是与对方有关不同。在不同收费时期的混合的油和烃迁居和累积机制的起源的调查具有到在这个区域的石油探索的大意义。 | YANG Haijun LI Sumei PANG Xiongqi XIAO Zhongyao GU Qiaoyuan ZHANG Baoshou | 2010 | Acta Geologica Sinica(English Edition)2010，84，5： | 5 |
| 8 | The Distribution of Dissolved Aluminum in the Yellow and East China Seas显示文摘Water samples containing dissolved aluminum were collected from the Yellow and East China Seas in Octo- ber-November 2000. The average concentrations of dissolved Al in the Yellow Sea (YS) and East China Sea (ECS) were 0.042 and 0.056 μmolL-1, respectively. The concentration of dissolved aluminum decreased gradually across the continental shelf. The lower concentrations appeared in the YS cold water center and in the bottom layer at the shelf edge of the ECS, where they were 0.016 and 0.011 μmolL-1, respectively. The distribution of dissolved Al was controlled by physical mixing processes rather than biological up- take processes. The impact of different water masses along the PN transect was calculated based on the mass balance model. The results show that the impact of the Changjiang River was mainly concentrated on the coastal area and the top thermocline water on the ECS shelf, where the impact percentage decreased from 12.6% to 1.1% in the surface water, while the contribution of the Ku- roshio water was dominant on the ECS shelf in this survey, increasing from 77.6% to 97.8% along the PN transect from the Changjiang River Estuary to the Ryukyu Islands. It is concluded that aluminum can serve as a proper tracer for studying the impact of Changjiang terrestrial matter on the ECS shelf water. | LI Jianbing REN Jingling ZHANG Jing LIU Sumei | 2008 | Journal of Ocean University of China2008，7，1： | 5 |
| 9 | The biogeochemical behavior of dissolved aluminum in the southern Yellow Sea:Influence of the spring phytoplankton bloom显示文摘Many recent studies have investigated the nutrient-type profiles of dissolved aluminum(Al) in the ocean.Significant scavenging of dissolved Al can occur during phytoplankton blooms,but the mechanism remains unclear.The distribution of dissolved Al in the southern Yellow Sea(SYS) was investigated in winter and spring 2009.Following measurements at grid stations during the spring sampling cruise,two drifting anchor surveys of more than 100 h were conducted to trace the variation of dissolved Al concentration during the spring phytoplankton bloom(SPB).The concentration of dissolved Al in the SYS decreased from 40 nmol/L in February to 30 nmol/L in March and 10-20 nmol/L in April,while the concentration of Chl a increased from < 2 μg/L in March to > 4 μg/L in April.The concentration of dissolved Al in the SYS decreased significantly with the development of the phytoplankton bloom,which indicated biological scavenging of dissolved Al from water column.The proportion of dissolved Al scavenged from water column by different phytoplankton species differed at the two drifting stations,with greater removal efficiency demonstrated by diatoms than dinoflagellates.Phytoplankton samples collected from the Chl a maximum layer were washed with trace metal clean reagent(oxalate-EDTA-citrate,abbreviate as oxalate solution,Tovar-Sanchez et al.,2003) to enable the surface-scavenged(extracellular) and intracellular Al pools associated with phytoplankton to be differentiated.Thirty-nine to ninetysix percent of the total Al was found to be existed in the interior pools,which indicated that biological absorption was the important way to scavenge dissolved Al during phytoplankton blooms in the SYS. | LI FaMing REN JingLing YAN Li LIU SuMei LIU ChengGang ZHOU Feng ZHANG Jing | 2013 | Chinese Science Bulletin2013，58，2： | 4 |
| 10 | Dye-sensitized Solar Cells with Higher J_(sc) by Using Polyvinylidene Fluoride Membrane Counter Electrodes显示文摘A flexible counter electrode(CE) for dye-sensitized solar cells(DSCs) has been fabricated using a micro-porous polyvinylidene fluoride membrane as support media and sputtered Pt as the catalytic material.Non-conventional structure DSCs have been developed by the fabricated CEs. The Pt metal was sputtered onto one surface of the membrane as the catalytic material. DSCs were assembled by attaching the Ti O2 electrode to the membrane surface without Pt coating. The membrane was with cylindrical pore geometry. It served not only as a substrate for the CE but also as a spacer for the DSC. The fabricated DSC with the flexible membrane CE showed higher photocurrent density than the conventional sandwich devices based on chemically deposited Pt/FTO glass, achieving a photovoltaic conversion efficiency of 4.43%. The results provides useful information in investigation and development of stable, low-cost, simple-design, flexible and lightweight DSCs. | Xiaodong Li Dingwen Zhang Si Chen Heng Zhang Zhuo Sun Sumei Huang Xijiang Yin | 2011 | Nano-Micro Letters2011，3，3： | 3 |
| 11 | Palm oil protectsα-linolenic acid from rumen biohydrogenation and muscle oxidation in cashmere goat kids显示文摘Background:In ruminants,dietary C18:3n-3 can be lost through biohydrogenation in the rumen;and C18:3n-3 that by-passes the rumen still can be lost through oxidation in muscle,theoretically reducing the deposition of C18:3n-3,the substrate for synthesis of poly-unsaturated fatty acids(n-3 LCPUFA)in muscle.In vitro studies have shown that rumen hydrogenation of C18:3n-3 is reduced by supplementation with palm oil(rich in cis-9 C18:1).In addition,in hepatocytes,studies with neonatal rats have shown that cis-9 C18:1 inhibits the oxidation of C18:3n-3.It therefore seems likely that palm oil could reduce both rumen biohydrogenation of C18:3n-3 and muscle oxidation of C18:3n-3.The present experiment tested whether the addition of palm oil to a linseed oil supplement for goat kids would prevent the losses of C18:3n-3 and thus improve the FA composition in two muscles,Longissimus dorsi and Biceps femoris.To investigate the processes involved,we studied the rumen bacterial communities and measured the mRNA expression of genes related to lipid metabolism in Longissimus dorsi.Sixty 4-month-old castrated male Albas white cashmere kids were randomly allocated among three dietary treatments.All three diets contained the same ingredients in the same proportions,but differed in their fat additives:palm oil(PMO),linseed oil(LSO)or mixed oil(MIX;2 parts linseed oil plus 1 part palm oil on a weight basis).Results:Compared with the LSO diet,the MIX diet decreased the relative abuandance of Pseudobutyrivibrio,a bacterial species that is positively related to the proportional loss rate of dietary C18:3n-3 and that has been reported to generate the ATP required for biohydrogenation(reflecting a decrease in the abundance of rumen bacteria that hydrogenate C18:3n-3 in MIX kids).In muscle,the MIX diet increased concentrations of C18:3n-3,C20:5n-3,C22:6n-3,and n-3 LCPUFA,and thus decreased the n-6/n-3 ratio;decreased the mRNA expression of CPT1β(a gene associated with fatty acid oxidation)and increased the mRNA expression of FADS1 and FADS2(genes associated with n-3 LCPUFA synthesis),compared with the LSO diet.Interestingly,compared to Longissimus dorsi,Biceps femoris had greater concentrations of PUFA,greater ratios of unsaturated fatty acids/saturated fatty acids(U/S),and poly-unsaturated fatty acids/saturated fatty acids(P/S),but a lesser concentration of saturated fatty acids(SFA).Conclusions:In cashmere goat kids,a combination of linseed and palm oils in the diet increases the muscle concentration of n-3 LCPUFA,apparently by decreasing the relative abundance of rumen bacteria that are positively related to the proportional loss rate of dietary C18:3n-3,by inhibiting mRNA expression of genes related to C18:3n-3 oxidation in muscle,and by up-regulating mRNA expression of genes related to n-3 LCPUFA synthesis in muscle,especially in Longissimus dorsi. | Xue Wang Graeme B.Martin Qi Wen Shulin Liu Yinhao Li Binlin Shi Xiaoyu Guo Yanli Zhao Yangdong Guo Sumei Yan | 2021 | Journal of Animal Science and Biotechnology2021，12，2： | 3 |
| 12 | Origin of Oils in“Subtle pools”in the Dongying Depression,Bohai Bay Basin, China显示文摘摘要:微妙的陷井或油水池在 Dongying 消沉成为了一出重要探索戏, Bohai 海湾盆,华东。尽管有在探索的最近的成功,微妙的陷井的形成机制仍然不好被理解。在 Dongying 消沉的微妙的油水池的多数与主要具有在 mudstones 包含的透镜的盆地板 turbidite 沙的微妙的陷井在 Paleogene Shahejie 形成的 Es3 成员的中间的间隔被开发。在微妙的陷井的油以前被认为从一样的形成(Es3 ) 的包围来源岩石直接移植了。从消沉的 41 油和 41 件岩石样品的详细 geochemical 调查现在显示从微妙的陷井的油不能与包围 Es3 来源岩石被相关很好,它被高 Pr/Ph 描绘(> 1 ) ,低 Gammacerane/C30hopane,代表淡水湖的背景。在对比油特征低 Pr/Ph (< 1 ) 并且相对高的 Gammacerane 内容,与内在的 Es4 来源一起显示出一种基因亲密关系摇,它也有一样的质量,显示一个略有盐味的湖的背景。在 Es3 微妙的陷井的油可能从支配的上面的 Es4 来源岩石与贡献从混合来源被导出。要调用解释从 Es4 来源岩石分享油的因此异乎寻常的油迁居和累积机制需要,它可能通过 Es3 来源的厚低间隔来了摇没有明显结构或 stratigraphic 小径。我们建议微妙的油迁居小径可能这里起一个重要作用。这发现可以在 Dongying 消沉为未来探索和留下的资源评估有重要含意。 | LI Sumei JIANG Zhengxue LIU Keyu QIU Guiqiang GAO Yongjin | 2008 | Acta Geologica Sinica(English Edition)2008，82，1： | 3 |
| 13 | Formation and Accumulation of Hydrocarbons in the Central Uplift,Dongying Depression显示文摘A large number of crude oil and rock samples from various oil pools of the Central Uplift in Dongying Depression were investigated to reveal the origin and accumulation of hydrocarbons. The results showed that the composition and areal distribution of hydrocarbons vary with the location of the oil pools. An increasing trend of gammacerane/C30-hopane and steranes/hopanes but a decreasing trend of prystane/phytane (Pr/Ph) and 18(H)-/17(H)-trisnorhopane (Ts/Tm) ratios were observed from southwest to northeast. This indicates a variation of source rocks and hydrocarbon properties. An increasing trend of water salinity with much more input of algae-rich microorganisms in the deposition environment of the source rock was observed from southwest to northeast. However, the thermal maturity of the source rocks showed a decreasing trend in the same direction. Oil-to-oil and oil-to-source rock correlations showed that most oils were sourced from Es3 and Es4 members with a burial depth of more than 3,000-3,150 m and 2,700 m respectively. The oils in the Shinan and Ying 11 sand bodies, which were generally mixed with the Es4 sourced oils, came mostly from Es3 mudstones. It is quite significant that the Es4 derived oils migrated vertically for hundreds of meters and accumulated in an overlying lithologic pool of the Es3m, i.e., Ying 11 synclinal lithologic pool, which suggests that the mechanisms of migration and accumulation for subtle oil pools in the Dongying Depression are more complex than that of the previously expected. | Li Sumei Qiu Guiqiang Gao Yongjin Jiang Zhenxue | 2006 | Petroleum Science2006，3，3： | 3 |
| 14 | Distribution of Dissolved Inorganic Arsenic and Its Seasonal Variations in the Coastal Area of the East China Sea显示文摘Water samples were collected in the coastal area of the Changjiang Estuary on four cruises from August 2002 to May 2003. The seasonal variations of dissolved inorganic arsenic (DIAs) distributions were analyzed. The results showed that the distributions of DIAs were mainly influenced by the terrestrial input and the intrusion of the Kuroshio Subsurface Water (KSSW). The concentration of the total dissolved inorganic arsenic (TDIAs) decreased consecutively from winter to summer, while it increased in autumn. The distributions of TDIAs showed some relationships with salinity and suspended particulate matter (SPM). The relationships between DIAs speciation (including arsenite [As(Ⅲ)] and arsenate [As(Ⅴ)]), biological activity and the availabilities of the phosphate were investigated in the study area for the cruise August 2002. The ratio of As (Ⅲ)/TDIAs increased with the decrease of phosphate concentrations. In the bottom water, the As(Ⅲ)/TDIAs ratio decreased with the increasing of N/P. The concentration of TDIAs decreased 28.7% approximately after the occurrence of harmful algal blooms (HAB) because of the uptake of arsenate by algae. Further study is needed about the arsenic source/sink relationships in their vertical or horizontal profiles and the uptake mechanism during the occurrence of harmful algal blooms. | CHENG Yan REN Jingling LI Dandan LIU Sumei ZHANG Jing | 2006 | Journal of Ocean University of China2006，5，3： | 3 |
| 15 | Rho-associated protein kinase modulates neurite extension by regulating microtubule remodeling and vinculin distribution显示文摘Rho-associated protein kinase is an essential regulator of cytoskeletal dynamics during the process of neurite extension.However,whether Rho kinase regulates microtubule remodeling or the distribution of adhesive proteins to mediate neurite outgrowth remains unclear.By specifically modulating Rho kinase activity with pharmacological agents,we studied the morpho-dynamics of neurite outgrowth.We found that lysophosphatidic acid,an activator of Rho kinase,inhibited neurite outgrowth,which could be reversed by Y-27632,an inhibitor of Rho kinase.Meanwhile,reorganization of microtubules was noticed during these processes,as indicated by their significant changes in the soma and growth cone.In addition,exposure to lysophosphatidic acid led to a decreased membrane distribution of vinculin,a focal adhesion protein in neurons,whereas Y-27632 recruited vinculin to the membrane.Taken together,our data suggest that Rho kinase regulates rat hippocampal neurite growth and microtubule formation via a mechanism associated with the redistribution of vinculin. | Ke'en Chen Wenbin Zhang Jing Chen Sumei Li Guoqing Guo | 2013 | Neural Regeneration Research2013，8，32： | 3 |
| 16 | Petroleum source in the Tazhong Uplift, Tarim Basin: New insights from geochemical and fluid inclusion data显示文摘 | Sumei Li Xiongqi Pang Zhijun Jin Haijun Yang Zhongyao Xiao Qiaoyuan Gu Baoshou Zhang | 2010 | Organic Geochemistry2010，，： | 2 |
| 17 | Quantitative prediction of mixed-source crude oils and its significance for understanding oil accumulation in subtle pools in the Dongying Depression,Bohai Bay Basin显示文摘常规 geochemical 途径在原油从 Paleogene Shahejie 形成的 Es3 和 Es4 成员导出的混合来源的比例的量的预言被利用。混合来源油在 Niuzhuang 在 Es3 成员(Es3 M ) 的中间的间隔被积累下垂,它是微妙的陷井在主要在 Dongying 消沉开发的 mudstones 以内的透镜的盆地板 turbidite 沙主要的 sags 之一, Bohai 海湾盆。结果证明大约 1892% 混合来源油与 5560% 的一般水准从 Es4 来源岩石被导出。与深差错联系的水库看起来有基因亲密关系上油的更多 Es4。导出 Es4 的油的一个高比例在 Es3 M 微妙的 lithological 发现在 Niuzhuang 的陷井下垂有长迁居距离。这建议包围来源岩石可能未必为微妙的陷井控制烃供应。微妙的迁居小径可以在垂直的油迁居起一个重要作用。在在从包围来源岩石的短迁居距离以内的这些透镜的 turbidite 沙岩陷井的烃累积的传统的概念是没由这研究支持。现在的结果与我们在在 Niuzhuang 的南方斜坡的 Bamianhe 油矿的不成熟的油下垂的以前的调查结果也一致实际上是主要在 Niuzhuang 的 depocenter 从 Es4 采购的混合来源油下垂,并且在 Dongying 消沉的 Es4 成员的石油潜力应该因此被重新估计。 | Li Sumei Liu Keyu Pang Xiongqi Li Maowen Jiang Zhenxue Qiu Guiqiang Gao Yongjin | 2008 | Petroleum Science2008，5，3： | 2 |
| 18 | Origin of Crude Oil in the Lunnan Region,Tarim Basin显示文摘Tarim 盆的油来源在很长时间是争论的。这研究描绘原油并且在 Lunnan 区域调查油来源,由采用 n 链烷和 biomarkers 的复合特定的同位素的 Tarim 盆来临。尽管原油与中间上面的奥陶纪( O2+3 )有好关联,采购有寒武纪降低奥陶纪的岩石和差的关联(-O1)基于 biomarkers , Lunnan 的n链烷的? 13C 数据给表演上油在 -O1 和 O2+3 之间的中间的价值基因亲密关系油,它建议 Lunnan 油实际上具有广泛地混合的来源。混合的油的 quantification 被执行,结果证明寒武纪降低奥陶纪来源的贡献从 11% ~ 70% 摇范围(平均 36%) ,稍微不到 Tazhong 的高举。在在决定油的 biomarkers 和 13C 之间的矛盾在至少一个事件和不同来源与不同化学部件从多重石油费用事件在 Lunnan 区域结果采购原料,这被建议。在盆的普遍海洋的混合来源油显示在深地平线的重要石油潜力是可能的。解开为 Lunnan 油的烃累积机制是关键的在这个区域推进石油探索和利用。 | LI Sumei PANG Xiongqi YANG Haijun XIAO Zhongyao GU Qiaoyuan ZHANG Baoshou WANG Haijiang | 2010 | Acta Geologica Sinica(English Edition)2010，84，5： | 2 |
| 19 | Distribution and Significance of Methyl Steranes in Bohai Bay Basin, East China显示文摘samples of shales and mudstones developed in reducing hypersaline and freshwater setting and 20 oil samples of Bamianhe oilfield, Bohai Bay basin were collected for a detailed study of petroleum system. Composition and distribution, especially significance of steroids, are discussed as a part of those. Abundant steroidal biomarkers, including C 27-29regular steranes, C 28-304-methyl steranes, dinosteranes and aromatic steranes, were detected. Results show that the composition and distribution of the steroids in samples studied are functions of thermal maturity, organic source, paleoenvironment and lithology of potential source rocks. Alga-rich E s 4 shales (brackish water) developed in the south slope of depocenter (Niuzhuang sag) were found particularly rich in steroidal biomarkers including C 304-methyl steranes and dinosteranes. E s 3 mudstones (fresh water) were found devoid of dinosteranes. Distribution patterns of regular steranes are completely different from methyl steranes indicating different origins of the specific compounds of the fraction. Diagnostic distribution of steranes in rock extracts of diverse intervals makes the compounds to be essential indictors of source-rock tracing. Methyl steranes prove to be much more useful in oil-source rock correlation than regular steranes. Results also show that alga-rich E s 4 shales located in the south slope are not likely the primary source rock responsible for the oils discovered based on the composition and distribution of steroids. | Li Sumei Basin & Reservoir Research Center, University of Petroleum, Beijing 102249 | 2002 | Journal of China University of Geosciences2002，13，4： | 2 |
| 20 | Lineage tracing reveals the origin of Nestin-positive cells are heterogeneous and rarely from ependymal cells after spinal cord injury显示文摘Nestin is expressed extensively in neural stem/progenitor cells during neural development, but its expression is mainly restricted to the ependymal cells in the adult spinal cord. After spinal cord injury(SCI), Nestin expression is reactivated and Nestinpositive(Nestin;) cells aggregate at the injury site. However, the derivation of Nestin;cells is not clearly defined. Here, we found that Nestin expression was substantially increased in the lesion edge and lesion core after SCI. Using a tamoxifen inducible CreER(T2)-loxP system, we verified that ependymal cells contribute few Nestin;cells either to the lesion core or the lesion edge after SCI. In the lesion edge, GFAP+astrocytes were the main cell type that expressed Nestin;they then formed an astrocyte scar.In the lesion core, Nestin;cells expressed αSMA or Desmin, indicating that they might be derived from pericytes. Our results reveal that Nestin;cells in the lesion core and edge came from various cell types and rarely from ependymal cells after complete transected SCI, which may provide new insights into SCI repair. | Xiaoyu Xue Muya Shu Zhifeng Xiao Yannan Zhao Xing Li Haipeng Zhang Yongheng Fan Xianming Wu Bing Chen Bai Xu Yaming Yang Weiyuan Liu Sumei Liu Jianwu Dai | 2022 | Science China(Life Sciences)2022，65，4： | 2 |
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