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| 1 | Impacts of climate gradients on the vegetation phenology of major land use types in Central Asia (1981-2008)显示文摘土地的时间系列关于植被生长模式的表面物候学(LSP ) 数据提议卓见。他们能被利用陆地表面部件的时间、光谱的反射性质产生。Interannual 和季节的 LSP 数据为理解并且预言一个生态系统的反应到生来、人为的驱动程序引起的变化是重要的。这研究在中亚检验在陆上的物候学和 28 年气候动力学之间的时间空间的变化模式和相互作用。长期(1981-2008 ) 象成长季节和植被生产率的开始,山峰和长度预定那样的 LSP 记录从遥远地察觉到的植被新鲜数据被导出。模式被分析在地区性的规模识别并且描绘气候司机的影响。我们探索了在 phenological 和降水之间的关系,为三的温度变量概括了暴露于地区性的干旱事件和加强的土地和水资源使用的 decadelong 的陆地使用类型:rainfed 农业,灌溉农业,和非农业。决定是否并且 LSP 动力学怎么与气候模式被联系,在这二个变量之间的一系列简单线性回归分析被执行。三个陆地使用班越过中亚显示出唯一的 phenological 回答到气候变化。大多数 phenological 反应变量被显示断然被相关到降水并且否定地相关到温度。影响所有三个陆地使用班的 phenological 回答的最实质的气候变量是春天温度政体。这些结果显示更高的温度将引起更早、更长的成长季节的那未来[出版摘要] | Jahan KARIYEVA Willem J.D. van LEEUWEN Connie A. WOODHOUSE | 2012 | Frontiers of Earth Science2012，6，2： | 10 |
| 2 | Effect of competing solutes on arsenic(Ⅴ) adsorption using iron and aluminum oxides显示文摘The study focused on the effect of several typical competing solutes on removal of arsenic with Fe_2O_3 and AL_2O_3.The test results indicate that chloride,nitrate and sulfate did not have detectable effects,and that selenium(Ⅳ)(Se(Ⅳ))and vanadium(Ⅴ)(V(Ⅴ)) showed slight effects on the adsorption of As(Ⅴ)with Fe_2O_3.The results also showed that adsorption of As(Ⅴ)on AL_2O_3 was not affected by chloride and nitrate anions,but slightly by Se(Ⅳ)and V(Ⅴ)ions.Unlike the adsorption of As(Ⅴ)with Fe_2O_3,that with Fe_2O_3 was affected by the presence of sulfate in water solutions.Both phosphate and silica have significant adverse effects on the adsorption of As(Ⅴ)adsorption with Fe_2O_3 and Al_2O_3.Compared to the other tested anions,phosphate anion was found to be the most prominent solute affecting the As(Ⅴ)adsorption with Fe_2O_3 and Al_2O_3.In general,Fe_2O_3 has a better performance than Al_2O_3 in removal of As(Ⅴ)within a water environment where multi competing solutes are present. | Youngran Jeong FAN Maohong Johannes Van Leeuwen Joshua F. Belczyk | 2007 | Journal of Environmental Sciences2007，19，8： | 10 |
| 3 | Oxidation of As(Ⅲ) by potassium permanganate显示文摘The oxidation of As(Ⅲ) with potassium permanganate was studied under conditions including pH, initial As(Ⅲ) concentration and dosage of Mn(VII). The results have shown that potassium permanganate was an effective agent for oxidation of As(Ⅲ) in a wide pH range. The pH value of tested water was not a significant factor affecting the oxidation of As(Ⅲ) by Mn(VII). Although theoretical redox analyses suggest that Mn(VII) should have better performance in oxidization of As(Ⅲ) within lower pH ranges, the experimental results show that the oxidation effciencies of As(Ⅲ) under basic and acidic conditions were similar, which may be due to the adsorption of As(Ⅲ) on the Mn(OH)2 and MnO2 resulting from the oxidation of As(Ⅲ). | LI Na FAN Maohong Van Leeuwen Johannes Saha Basudeb YANG Hongqun HUANG C. P. | 2007 | Journal of Environmental Sciences2007，19，7： | 10 |
| 4 | Glutamate reduces experimental intestinal hyperpermeability and facilitates glutamine support of gut integrity显示文摘AIM:To assess whether glutamate plays a similar role to glutamine in preserving gut wall integrity.METHODS:The effects of glutamine and glutamate on induced hyperpermeability in intestinal cell lines were studied.Paracellular hyperpermeability was induced in Caco2.BBE and HT-29CL.19A cell lines by adding phorbol-12,13-dibutyrate(PDB) apically,after which the effects of glutamine and glutamate on horseradish peroxidase(HRP) diffusion were studied.An inhibitor of glutamate transport(L-trans-pyrrolidine-2,4-dicarboxylic acid:trans-PDC) and an irreversible blocker(acivicin) of the extracellular glutamine to glutamate converting enzyme,γ-glutamyltransferase,were used.RESULTS:Apical to basolateral HRP flux increased significantly compared to controls not exposed to PDB (n=30,P<0.001).Glutamine application reduced hyperpermeability by 19%and 39%in the respective cell lines.Glutamate application reduced hyperpermeability by 30%and 20%,respectively.Incubation of HT29CL.19A cells with acivicin and subsequent PDB and glutamine addition increased permeability levels.Incubation of Caco2.BBE cells with trans-PDC followed by PDB and glutamate addition also resulted in high permeability levels.CONCLUSION:Apical glutamate-similar to glutaminecan decrease induced paracellular hyperpermeability.Extracellular conversion of glutamine to glutamate and subsequent uptake of glutamate could be a pivotal step in the mechanism underlying the protective effect of glutamine. | Mechteld AR Vermeulen Jeffrey de Jong Mathijs J Vaessen Paul AM van Leeuwen Alexander PJ Houdijk | 2011 | World Journal of Gastroenterology2011，17，12： | 9 |
| 5 | Influence of coagulation mechanisms and floc formation on filterability显示文摘Minimizing particles in water is a key goal for improving drinking water quality and safety.The media filtration process,as the last step of the solid–liquid separation process,is largely influenced by the characteristics of flocs,which are formed and controlled within the coagulation process.In a laboratory-based study,the impacts of the physical characteristics of flocs formed using aluminum sulfate on the filtration treatment of two comparative water samples were investigated using a photometric dispersion analyzer and a filterability apparatus.In general,the optimum dosage for maximizing filterability was higher than that for minimizing turbidity under neutral p H conditions.For a monomeric aluminum-based coagulant,the charge neutralization mechanism produced better floc characteristics,including floc growth speed and size,than the sweep flocculation mechanism.In addition,the charge neutralization mechanism showed better performance compared to sweep flocculation in terms of DOC removal and floc filterability improvement for both waters,and showed superiority in turbidity removal only when the raw water had high turbidity.For the different mechanisms,the ways that floc characteristics impacted on floc filterability also differed.The low variation in floc size distribution obtained under the charge neutralization mechanism resulted in the flocs being amenable to removal by filtration processes.For the sweep flocculation mechanism,increasing the floc size improved the settling ability of flocs,resulting in higher filter efficiency. | Ruyuan Jiao Rolando Fabris Christopher W.K.Chow Mary Drikas John van Leeuwen Dongsheng Wang Zhizhen Xu | 2017 | Journal of Environmental Sciences2017，29，7： | 6 |
| 6 | pH modeling for maximum dissolved organic matter removal by enhanced coagulation显示文摘Correlations between raw water characteristics and pH after enhanced coagulation to maximize dissolved organic matter(DOM) removal using four typical coagulants(FeCl3,Al2(SO4)3,polyaluminum chloride(PACl) and high performance polyaluminum chloride(HPAC)) without pH control were investigated.These correlations were analyzed on the basis of the raw water quality and the chemical and physical fractionations of DOM of thirteen Chinese source waters over three seasons.It was found that the final pH after enhanced coagulation for each of the four coagulants was in?uenced by the content of removable DOM(i.e.hydrophobic and higher apparent molecular weight(AMW) DOM),the alkalinity and the initial pH of raw water.A set of feed-forward semi-empirical models relating the final pH after enhanced coagulation for each of the four coagulants with the raw water characteristics were developed and optimized based on correlation analysis.The established models were preliminarily validated for prediction purposes,and it was found that the deviation between the predicted data and actual data was low.This result demonstrated the potential for the application of these models in practical operation of drinking water treatment plants. | Jiankun Xie Dongsheng Wang John van Leeuwen Yanmei Zhao Linan Xing Christopher W. K. Chow | 2012 | Journal of Environmental Sciences2012，24，2： | 5 |
| 7 | Prediction of DOM removal of low specific UV absorbance surface waters using HPSEC combined with peak fitting显示文摘High performance size exclusion chromatography (HPSEC) is used in water quality research primarily to determine the molecular weight distribution of the dissolved organic matter (DOM), but by applying peak fitting to the chromatogram, this technique can also be used as a tool to model and predict DOM removal. Six low specific UV absorbance (SUVA) source waters were treated using coagulation with alum and both the source and treated water samples were analysed using HPSEC. By comparing the molecular weight profiles of the source and treated waters, it was established that several DOM components were not effectively removed by alum coagulation even after high dosage alum treatment. A peak-fitting technique was applied based on the concept of linking the character (molecular weight profile) of the recalcitrant organics in the treated water with those of the source water. This was then applied to predict DOM treatability by determining the areas of the peaks which were assigned to removable organics from the source water molecular weight profile after peak fitting, and this technique quantified the removable and non-removable organics. The prediction was compared with the actual dissolved organic carbon (DOC) removal determined from jar testing and showed good agreement, with variance between 2% and 10%. This confirmed that this prediction approach, which was originally developed for high SUVA waters, can also be applied successfully to predict DOC removal in low SUVA waters. | Linan Xing Rolando Fabris W.K.Chow John van Leeuwen Mary Drikas Dongsheng Wang | 2012 | Journal of Environmental Sciences2012，24，7： | 4 |
| 8 | Antioxidant enriched enteral nutrition and oxidative stress after major gastrointestinal tract surgery显示文摘AIM: To investigate the effects of an enteral supple-ment containing antioxidants on circulating levels of antioxidants and indicators of oxidative stress after major gastrointestinal surgery.METHODS: Twenty-one patients undergoing major upper gastrointestinal tract surgery were randomised in a single centre, open label study on the effect of postoperative enteral nutrition supplementedwith antioxidants. The effect on circulating levels of antioxidants and indicators of oxidative stress, such as F2-isoprostane, was studied. RESULTS: The antioxidant enteral supplement showed no adverse effects and was well tolerated. After surgery a decrease in the circulating levels of antioxidant parameters was observed. Only selenium and glutamine levels were restored to pre-operative values one week after surgery. F2-isoprostane increased in the first three postoperative days only in the antioxidant supplemented group. Lipopolysaccharide binding protein (LBP) levels decreased faster in the antioxidant group after surgery.CONCLUSION: Despite lower antioxidant levels there was no increase in the circulating markers of oxidative stress on the first day after major abdominal surgery. The rise in F2-isoprostane in patients receiving the antioxidant supplement may be related to the conversion of antioxidants to oxidants which raises questions on antioxidant supplementation. Module AOX restored the postoperative decrease in selenium levels. The rapid decrease in LBP levels in the antioxidant group suggests a possible protective effect on gut wall integrity. Further studies are needed on the role of oxidative stress on outcome and the use of antioxidants in patients undergoing major abdominal surgery. | Mireille FM van Stijn Gerdien C Ligthart-Melis Petra G Boelens Peter G Scheffer Tom Teerlink Jos WR Twisk Alexander PJ Houdijk Paul AM van Leeuwen | 2008 | World Journal of Gastroenterology2008，14，45： | 4 |
| 9 | Presence of a high amount of stroma and downregulation of SMAD4 predict for worse survival for stage I–II colon cancer patients显示文摘 | Wilma E. Mesker Gerrit-Jan Liefers Jan M.C. Junggeburt Gabi W. van Pelt Paola Alberici Peter J.K. Kuppen Noel F. Miranda Karin A.M. van Leeuwen Hans Morreau Karoly Szuhai Rob A.E.M. Tollenaar Hans J. Tanke | 2009 | Cellular Oncology2009，，3： | 2 |
| 10 | miR-133 and miR-30 Regulate Connective Tissue Growth Factor: Implications for a Role of MicroRNAs in Myocardial Matrix Remodeling显示文摘 | Rudy F. Duisters Anke J. Tijsen Blanche Schroen Joost J. Leenders Viola Lentink Ingeborg van der Made Veronica Herias Rick E. van Leeuwen Mark W. Schellings Paul Barenbrug Jos G. Maessen Stephane Heymans Yigal M. Pinto Esther E. Creemers | 2009 | Circulation Research2009，，： | 2 |
| 11 | Preoperative Imaging of Colorectal Liver Metastases After Neoadjuvant Chemotherapy: A Meta-Analysis显示文摘 | Charlotte Kessel Constantinus Buckens Maurice Bosch Maarten Leeuwen Richard Hillegersberg Helena Verkooijen | 2012 | Annals of Surgical Oncology2012，，9： | 2 |
| 12 | Noise prediction models to determine the effect of barriers placed alongside railway lines 显示文摘 | Van Leeuwen J J A | 1996 | Journal of Sound and Vibration1996，193，1： | 2 |
| 13 | The kinetics of producing sulfate-based complex coagulant from fly ash 显示文摘 | Fan M Brown R C Van Leeuwen J | 2003 | Chemical Engineering and Processing2003，42，12： | 1 |
| 14 | Priority setting for existing chemicals : The European Union risk ranking method 显示文摘 | HANSEN B J VAN HAELST A G VAN LEEUWEN K | 1999 | Environ Toxicol Chem1999，18，： | 1 |
| 15 | The role of high density lipoprotein in sepsis显示文摘 | van Leeuwen HJ van Beek AP Dallinga Thie GM | 2001 | Nerth J Med2001，59，3： | 1 |
| 16 | Follow-up results of different treatment programs for obese children显示文摘 | Braet C Winckel MV Leeuwen KV | 1997 | Acta paediatr1997，86，： | 1 |
| 17 | Effect of corticosteroids on nuclear facter-kappa B activation and hemodynamics in late septic shock显示文摘 | Leeuwen HJ Bruggen T Asbeck BS | 2001 | Crit Care Med2001，29，5： | 1 |
| 18 | Theprognostic value of anticytie citmllinated peptide antibody in patients with recent onset rhetunatoid arthritis显示文摘 | Kroot EJJA de Jong BAW Van Leeuwen MA | 2000 | Rheum2000，43，： | 1 |
| 19 | Flavonoids:a review of probable mechanisms of action and potential applications显示文摘 | NIJVELDT R J VAN NOOD E VAN HOORN D E BOELENS P G VAN NORREN K VAN LEEUWEN P A | 2001 | The American Journal of Clinical Nutrition2001，74，4： | 1 |
| 20 | The impact of canopy exchange on differences observed between atmospheric deposition and throughfall fluxes 显示文摘 | Draaijers G P J Erisman J W Van Leeuwen N F M | 1997 | Atmospheric Environment1997，31，3： | 1 |
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