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| 1 | Gender differences in efficacy of primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction显示文摘背景经皮的冠的干预(一种总线标准)的临床的结果在学习在在病人在主要一种总线标准的策略上把性差别的影响与尖锐圣片断举起作比较瞄准了的 men.This 比那在女人是更差的心肌的梗塞( STEMI ) .Methods 经历了的有 STEMI 的 259 个病人主要在 12 小时症状发作以内的一种总线标准是 enrolled.The 男组由 143 个男人组成了>没有年龄 lim , 55 年,和一个女组包括了 116 | LIU Yu WANG Le-feng YANG Xin-chun GE Yong-gui WANG Hong-shi XU Li LI Wei-ming NI Zhu-hua XIA Kun CHI Yong-hui LI Qiang ZHANG Da-peng WU Xiao-qing SUN Hao GUO Zong-sheng | 2008 | Chinese Medical Journal2008，，23： | 9 |
| 2 | Platelet function monitoring guided antiplatelet therapy in patients receiving high-risk coronary interventions显示文摘 | Xu Li Wang Lefeng Yang Xinchun Li Kuibao Sun Hao Zhang Dapeng Wang Hongshi Li Weiming Ni Zhuhua Xia Kun Liu Yu | 2014 | Chinese Medical Journal2014，，19： | 8 |
| 3 | Combined effects of cadmium and fluoranthene on germination, growth and photosynthesis of soybean seedlings显示文摘The single and combinational effects of cadmium (Cd) and fluoranthene (FLT) on germination, growth and photosynthesis of soybean seedlings were investigated. Exposure to 5, 10, or 15 mg Cd/L or 1, 5, or 10 mg FLT/L individually or in combination significantly decreased germination vigor (3 days) and final germination rate of soybean seeds, except at 1 and 5 mg FLT/L. The results of two-way ANOVA analysis and the Bliss independence model showed that at lower concentrations of FLT (1 mg/L), the interaction between Cd and FLT on germination was antagonistic, whereas the interaction was synergistic when the concentration of FLT was 5 or 10 mg/L and the concentration of Cd was 15 mg/L. Growth, expressed as dry weight, length of shoot and root, leaf area, and photosynthesis, expressed as net photosynthetic rate, intercellular CO2 concentration, chlorophyll contents and fluorescence of soybean seedlings were also reduced by exposure to 5 or 10 mg Cd/L or 1 or 5 mg FLT/L, singly or jointly. Significant antagonistic effects of exposure to 5 or 10 mg Cd/L or 1 or 5 mg FLT/L on shoot growth and photosynthesis were observed, whereas synergy and antagonism of Cd and FLT were both observed for root growth. | Qiushuang Li Yonglong Lu Yajuan Shi Tieyu Wang Kun Ni Li Xu Shijie Liu Lin Wang Qinli Xiong John.P Giesy | 2013 | Journal of Environmental Sciences2013，25，9： | 8 |
| 4 | Serine metabolism orchestrates macrophage polarization by regulating the IGF1–p38 axis显示文摘Serine metabolism is reportedly involved in immune cell functions, but whether and how serine metabolism regulates macrophage polarization remain largely unknown. Here, we show that suppressing serine metabolism, either by inhibiting the activity of the key enzyme phosphoglycerate dehydrogenase in the serine biosynthesis pathway or by exogenous serine and glycine restriction, robustly enhances the polarization of interferon-γ-activated macrophages (M(IFN-γ)) but suppresses that of interleukin-4-activated macrophages (M(IL-4)) both in vitro and in vivo. Mechanistically, serine metabolism deficiency increases the expression of IGF1 by reducing the promoter abundance of S-adenosyl methionine-dependent histone H3 lysine 27 trimethylation. IGF1 then activates the p38-dependent JAK–STAT1 axis to promote M(IFN-γ) polarization and suppress STAT6-mediated M(IL-4) activation. This study reveals a new mechanism by which serine metabolism orchestrates macrophage polarization and suggests the manipulation of serine metabolism as a therapeutic strategy for macrophage-mediated immune diseases. | Xiao Shan Penghui Hu Lina Ni Long Shen Yanan Zhang Zemin Ji Yan Cui Meihua Guo Haoan Wang Liyuan Ran Kun Yang Ting Wang Lei Wang Bin Chen Zhi Yao Vingjie Wu Qiujing Yu | 2022 | Cellular & Molecular Immunology2022，19，11： | 5 |
| 5 | Qiguiyishen decoction reduced the accumulation of extracellular matrix in the kidneys of rats with adriamycin-induced nephropathy显示文摘OBJECTIVE: To investigate the effect of Qiguiyishen decoction(QGYS) on the severity of nephropathy.METHODS: Twenty-four rats were randomly divided into four groups(Ⅰ, Ⅱ, Ⅲ, Ⅳ) according to the random number table. Group Ⅰ as control group did not establish nephropathy model. Groups Ⅱ,Ⅲ, and Ⅳ were intravenously administered Adriamycin(7.5 mg/kg) through the tail vein to establish nephropathy model. QGYS was prepared with the extracts of Huangqi(Radix Astragali Mongolici),Danggui(Radix Angelicae Sinensis),Niuxi(RadixAchyran-this Bidentatae), and Chuanxiong(Rhizoma Chuanxiong).Group Ⅳ was administered QGYS (2mL·kg-1·d-1), group Ⅲ was administered benazepril(10 mL·kg-1·d-1), and group Ⅰ, Ⅱ was administered water(2mL·kg-1·d-1)once daily for eight weeks.RESULTS: QGYS reduced the excretion of urinary protein and N-acetyl-β-D-glucosaminidase and alleviated the accumulation of extracellular matrix(ECM) in renal tissue. Additionally, QGYS effectively regulated the levels of transforming growth factor,tissue inhibitor of matrix metalloproteinase, and matrixmetalloprote in asesin the kidney of the rats.CONCLUSION:QGYS may reduce the accumulation of ECM in the kidneys of rats with Adriamycin-induced nephropathy. | Minggang Wei Wei Sun Weiming He Li Ni Xiaofeng Cai Zongqi Cheng Kun Gao Fengling Li Lin Chen Xinping Zhang | 2014 | Journal of Traditional Chinese Medicine2014，34，3： | 4 |
| 6 | Factors influencing the contents of metals and As in soils around the watershed of Guanting Reservoir,China显示文摘Topsoil samples from 61 sites around the Guanting Reservoir,China,were measured for Cu,Zn,Cr,Ni,Cd,Pb and As concentrations.The mean concentrations of Cu,Zn,Cr,Ni,Cd,Pb and As were 16.8,59.4,37.8,18.3,0.32,20.1 and 8.67 mg/kg dry weight,respectively.Factors that influence the dynamics of these metals in soils around the watersheds of Beijing reservoirs were examined.The influence of atmospheric deposition,land use,soil texture,soil type and soil chemical parameters on metal contents in soils was investigated.Atmospheric deposition,land use and soil texture were the important factors affecting heavy metal residues.Soil type and soil chemical parameters were also involved in heavy metal retention in soils.The data provided in this study are considered crucial for reservoir remediation,especially since the Guanting Reservoir will serve as one of the main drinking water sources for Beijing in the foreseeable future. | Li Xu Tieyu Wang Wei Luo Kun Ni Shijie Liu Lin Wang Qiushuang Li Yonglong Lu | 2013 | Journal of Environmental Sciences2013，25，3： | 4 |
| 7 | Underwater Laser Welding/Cladding for High-performance Repair of Marine Metal Materials:A Review显示文摘With the rapid developments of marine resource exploitation,mounts of marine engineering equipment are settled on the ocean.When it is not possible to move the damaged equipment into a dry dock,welding operations must be performed in underwater environments.The underwater laser welding/cladding technique is a promising and advanced technique which could be widely applied to the maintenance of the damaged equipment.The present review paper aims to present a critical analysis and engineering overview of the underwater laser welding/cladding technique.First,we elaborated recent advances and key issues of drainage nozzles all over the world.Next,we presented the underwater laser processing and microstructural-mechanical behavior of repaired marine materials.Then,the newly developed powder-feeding based and wire-feeding based underwater laser direct metal deposition techniques were reviewed.The differences between the convection,conduction,and the metallurgical kinetics in the melt pools during underwater laser direct metal deposition and in-air laser direct metal deposition were illustrated.After that,several challenges that need to be overcame to achieve the full potential of the underwater laser welding/cladding technique are proposed.Finally,suggestions for future directions to aid the development of underwater laser welding/cladding technology and underwater metallurgical theory are provided.The present review will not only enrich the knowledge in the underwater repair technology,but also provide important guidance for the potential applications of the technology on the marine engineering. | Guifang Sun Zhandong Wang Yi Lu Mingzhi Chen Kun Yang Zhonghua Ni | 2022 | Chinese Journal of Mechanical Engineering2022，35，1： | 4 |
| 8 | Experimental study of the wake characteristics of a two-blade horizontal axis wind turbine by time-resolved PIV显示文摘Wind tunnel experiments of the wake characteristics of a two-blade wind turbine, in the downstream region of 0 | ZHANG LiRu XING JiangKuan WANG JianWen YUAN RenYu DONG XueQing MA JianLong LUO Kun QIU KunZan NI MingJiang CEN KeFa | 2017 | Science China(Technological Sciences)2017，60，4： | 4 |
| 9 | Risk of Treatment Failure in Patients with Drug-susceptible Pulmonary Tuberculosis in China显示文摘The objective of this prospective study of the risks of treatment failure in patients with drug-susceptible pulmonary tuberculosis(PTB)was to provide reference data to help develop a disease control strategy.Participants were recruited in eight provinces of China from October 2008 to December2010.A total of 1447 patients with | WANG Ni MA Yan LIU YU Hong DU Jian ZHANG Hui XIE Shi Heng Zhu Kun LYU Xiao Ya SHU Wei WANG Hong Hong ZHU Guo Feng TAN Shou Yong FU Yan Yong MA Li Ping ZHANG Lian Ying LIU Fei Ying HU Dai Yu ZHANG Yan Ling LI Xiang Qun LI Liang | 2016 | Biomedical and Environmental Sciences2016，29，8： | 3 |
| 10 | New insight into the stability and dynamics of fluid-conveying supported pipes with small geometric imperfections显示文摘In several previous studies,it was reported that a supported pipe with small geometric imperfections would lose stability when the internal flow velocity became sufficiently high.Recently,however,it has become clear that this conclusion may be at best incomplete.A reevaluation of the problem is undertaken here by essentially considering the flow-induced static deformation of a pipe.With the aid of the absolute nodal coordinate formulation(ANCF)and the extended Lagrange equations for dynamical systems containing non-material volumes,the nonlinear governing equations of a pipe with three different geometric imperfections are introduced and formulated.Based on extensive numerical calculations,the static equilibrium configuration,the stability,and the nonlinear dynamics of the considered pipe system are determined and analyzed.The results show that for a supported pipe with the geometric imperfection of a half sinusoidal wave,the dynamical system could not lose stability even if the flow velocity reaches an extremely high value of 40.However,for a supported pipe with the geometric imperfection of one or one and a half sinusoidal waves,the first-mode buckling instability would take place at high flow velocity.Moreover,based on a further parametric analysis,the effects of the amplitude of the geometric imperfection and the aspect ratio of the pipe on the static deformation,the critical flow velocity for buckling instability,and the nonlinear responses of the supported pipes with geometric imperfections are analyzed. | Kun ZHOU Qiao NI Wei CHEN Huliang DAI Zerui PENG Lin WANG | 2021 | Applied Mathematics and Mechanics(English Edition)2021，42，5： | 3 |
| 11 | Factors influencing polychlorinated dibenzo-p-dioxin and polychlorinated dibenzofuran (PCDD/F) emissions and control in major industrial sectors: Case evidence from Shandong Province, China显示文摘Analyzing determinants that influence polychlorinated dibenzo-p-dioxin and polychlorinated dibenzofuran(PCDD/F) emissions is helpful for decision-makers to find effective and efficient ways to mitigate PCDD/F emissions. The PCDD/F emissions and the contributions of the scale effect, structure effect and technology effect to emissions from eight main industrial sectors in2006, 2008 and 2010 in Shandong Province, were calculated in this article. Total PCDD/F emissions in Shandong increased by 52.8% in 2008(614.1 g I-TEQ) and 49.7% in 2010(601.8 g I-TEQ) based on 2006(401.9 g I-TEQ). According to the decomposition method, the largest influencing factor on PCDD/F emission changes was the composition effect(contributed 43.4%in 2008 and 120.6% in 2010 based on 2006), which was also an emission-increasing factor.In this case, the present industrial restructuring policy should be adjusted to control the proportion of production capacities with high emission factors, such as iron ore sintering and steelmaking and the secondary non-ferrous metal sector. The scale effect increased the emissions in 2008(contributed 21.9%) and decreased the emissions in 2010(contributed-28.0%). However, as a source control measure, the excess capacity control policy indeed had a significant role in emission reduction. The main reason for the technology effect(contributed 34.7% in 2008 and 7.4% in 2010 based on 2006) having an emission-increasing role was the weakness in implementing policies for restricting industries with outdated facilities. Some specific suggestions were proposed on PCDD/F reduction for local administrators at the end. | Lin Wang Yonglong Lu Guizhen He Arthur P.J.Mol Tieyu Wang Jorrit Gosens Kun Ni | 2014 | Journal of Environmental Sciences2014，26，7： | 2 |
| 12 | A Real-time Monitoring System Based on ZigBee and 4G Communications for Photovoltaic Generation显示文摘A novel real-time monitoring system for photovoltaic(PV)generation is presented in this paper.Internet of Things(IoT)integrated with cloud servers and terminal applications allow the remote monitoring of centralized or distributed pho-tovoltaic systems.The proposed system could realize the net-working communication of multiple nodes based on ZigBee,and upload the operational data to the cloud server via a 4G communications network.Then,the server selects three-phase current as the sample sets from the uploaded data to set up a composite current characteristic combining wavelet packet en-ergy with waveform parameter,and establishes a fault diagnosis model based on the probabilistic neural network to analyze the health status of the PV inverter online.This method requires little sampling frequency without an extra signal and saves the cost of local devices by placing online diagnostics on the server-side.In addition,the user could query and store the running information of the PV systems through the personal computer-side web or mobile phone with remote control.This article presents the hardware design of ZigBee and the 4G module,and composition of the diagnosis model for open circuit failure of the PV inverter through the cloud server,building the user software at the application layer.The final experimental results show that the proposed system has better communication performance and higher diagnostic accuracy in real-time monitoring. | Kun Xia Jiawen Ni Yanhong Ye Po Xu Yiming Wang | 2020 | CSEE Journal of Power and Energy Systems2020，6，1： | 2 |
| 13 | Prediction of properties distribution of 7B50 alloy thick plates after quenching and aging by quench factor analysis method显示文摘In the present work,continuous cooling curves were accurately measured by the modified Jominy specimen of 7B50 alloy during water-spray quenching tests.Besides,the time-temperature-properties(TTP) curves of this alloy were obtained during isothermal treatments.Based on the accurate cooling curves and TTP curves,the hardness distribution along the thickness direction of 7B50 alloy thick plates was predicted by quench factor analysis method.It is found that the quench sensitive temperature range of 7B50 alloy is 240-410℃,the nose temperature is 335℃,and the incubation period at the nose temperature is about 0.87 s.When 7B50 alloy was isothermal treated at 180-400℃ after solid solution treatment(470℃ for 1 h followed by 483℃ for 2 h),the exponent(n) in the Johnson-Mehl-Avrami equation is close to 1 until transformed fraction of new precipitates is up to 60%,indicating that new precipitates first grow into rodlike shape and then coarsen or thicken.When the distance is less than 65 mm from the spray quenching surface of the modified Jominy specimen,the deviation between the predicted and measured hardness is less than 2.7%,confirming the quench factor analysis method as the feasible way to predict the hardness distribution along the thickness direction of 7B50 alloy thick plates.When the distance from the spray quenching surface is 25 mm,the average cooling rate in quench sensitive temperature range is 9.93 ℃·s^-1,while the quench factor(τ) is 9.89 and the corresponding predicted hardness is HV 185.1 equivalent to 97.3% of the maximum measured hardness of 7B50 alloy in T6 temper. | Lei Kang Yi-Ran Zhou Gang Zhao Kun Liu Ni Tian | 2019 | Rare Metals2019，38，11： | 2 |
| 14 | pH-sensitive polymer-assisted refolding of urea-denatured fibroblast growth factor显示文摘pH 应答的聚合物 Eudragit S-100 被发现了在 FGF-2 (成纤维细胞生长 factor-2 ) 的正确合拢帮助的 A 在 pH 与 8 mol/L 脲和 10 mmol/L dithiothreitol 使中毒 7.2。FGF-2 的 refolding 被直接冲淡执行使中毒的 FGF-2 进包含 Eudragit S-100 的一个 refolding 缓冲区。Eudragit S-100 的能力用 MTT 方法,荧光排放光谱学和反向的阶段 HPLC 被调查提高蛋白质 refolding 水平。在另一方面,结果显示出提高蛋白质的 refolding 水平的 S-100 由于在 Eudragit S-100 之间的相互作用并且断然控告 FGF-2 的 Eudragit 的能力。 | Zhi Feng Huang Shan Shan Wang Chun Yan Ni Shu Lin Yang Xiao Kun Li Susanna S.J. Leong | 2009 | Chinese Chemical Letters2009，20，4： | 2 |
| 15 | Effective doctor-patient communication skills training optimizes functional organization of intrinsic brain architecture:a restingstate functional MRI study显示文摘We studied the influence of doctor-patient communication skills training on brain functional architecture using resting-state functional MRI(rs-fMRI) with a regional homogeneity(ReHo) method. Ten medical students participated in the study. A 1-year long doctor-patient communication skills training program was conducted. RsfMRI data were collected at baseline, one month and one year after training. There was a significant increase in the communication skills test average scores between baseline and 1-month duration of training(P<0.001). After one month of communication skills training, medical students had decreased ReHo in the right superior temporal gyrus compared with the baseline. After one year of communication skills training, students had increased ReHo in multiple regions and decreased ReHo in several regions(P <0.05, Alphasim corrected). The change of ReHo values in the superior temporal gyrus negatively correlated with the change of communication skills scale score between one month after communication skills training and baseline(r=-0.734, P= 0.036). The training program we used can be an effective approach of improving doctor-patient communication skills, and the training resulted in functional plasticity of the brain's architecture toward optimizing locally functional organization. | Bing Zhang Ling Ni Fangfang Wang Weiping Li Xin Zhang Xiaohua Gu Zuzana Nedelska Fei Chen Kun Wang Bin Zhu Renyuan Liu Jun Xu Jinfan Wang | 2017 | The Journal of Biomedical Research2017，31，6： | 2 |
| 16 | One-pot synthesis of 2,5-disubstituted-1,3,4-thiadiazoles under ultrasonic irradiation显示文摘A facile one-pot synthesis of 2,5-disubstituted-1,3,4-thiadiazoles was achieved by ultrasonic irradiation of a mixture of 1- naphthylacetyl chloride,NH4CNS,CH2Cl2 and PEG-400 for 1.5 h at 10-20℃and subsequent irradiation for 1.5h in the presence of N-arylglycine hydrazides.This method requires short time and gives thiadiazoles in high yields. | Ying Jun Li Ya Zhen Sun Yong Ting Xu Kun Jin Li Ping Wen Ni Bo Hou Xiao Xiao Sun | 2007 | Chinese Chemical Letters2007，18，9： | 1 |
| 17 | Efficient kinetic schemes for steady and unsteady flow simulations on unstructured meshes 显示文摘 | NI Guoxi JIANG Song XU Kun | 2008 | J Comput Phys2008，227，6： | 1 |
| 18 | Survival Benefit of Traditional Chinese Herbal Medicine (a Herbal Formula for Invigorating Spleen) for Patients With Advanced Gastric Cancer显示文摘 | Yan Xu Ai Guang Zhao Zhao Yan Li Gang Zhao Yong Cai Xiao Hong Zhu Ni Da Cao Jin Kun Yang Jian Zheng Yin Gu Ying Ying Han Ying Jie Zhu Jin Zu Yang Feng Gao Qiang Wang | 2013 | Integrative Cancer Therapies2013，，5： | 1 |
| 19 | Properties of mortars made by uncalcined FGD gypsum-fly ash-ground granulated blast furnace slag composite binder显示文摘 | Shiyun Zhong Kun Ni Jinmei Li | 2012 | Waste Management2012，，7： | 1 |
| 20 | Relationship between plant species diversity and patch characteristics in a marsh in the Sangjiang Plain,China—Using Yaluhe farm as an example显示文摘Based on Quick Bird satellite image data, the present study examined small-scale herbaceous community patches in the marsh of the Sanjiang Plain and measured patch characteristics such as the area, perimeter and shape by GPS. The coenological characteristics of the patches were investigated using quadrat method, and the vascular plant species were recorded using transect method. A total of 219 plant species were recorded, which represents 12.2% of the vascular flora in Heilongjiang Province. Our results showed that species number S correlated with patch area and perimeter; richness index (R) correlated with patch perimeter; Simpson index (D) correlated with patch area and perimeter/area; Shannon-Wiener index (H′) correlated with patch area, perimeter and perimeter/area; Evenness index (Jsw) correlated with perimeter/area. Both S and R have significant difference between different size of patches. Plant diversity in the small-scale herbaceous communities tended to increase with the patch area and perimeter. We concluded that edge effects and the habitat heterogeneity of the patches are important in determining the number of species. The relative smoothness of the patch edges also affects the plant diversity of the patches. The richness of plant species in the marsh in the Sanjiang Plain is highly sensitive to the small-scale patches, which continues to play an important role in preserving plant diversity in the local area. | Sun Zhonglin Xing Fu Lu Xianguo Xu Kun Yu Lili Ni Hongwei | 2007 | Progress in Natural Science:Materials International2007，17，6： | 1 |
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