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216篇 您的检索式:作者名="Kulkarni A D"
    题名 作者 年代 出处 被引量
1Ron receptor-dependent gene regulation in a mouse model of endotoxin-induced acute liver failure显示文摘BACKGROUND:Prior experimentation has shown that loss of the tyrosine kinase(TK) signaling domain of the Ron receptor leads to marked hepatocyte protection in a model of lipopolysaccharideinduced acute liver failure(ALF) in D-galactosamine(GalN)sensitized mice.The aim of this study was to identify the role of Ron in the regulation of hepatic gene expression.METHODS:Microarray analyses were performed on liver RNA isolated sequentially from wild-type(WT) and TK-/mice during the progression of ALF.Gene array data were validated using Western and immunohistochemistry analyses as well as with ex vivo culture systems.RESULTS:At baseline,101 genes were differentially expressed between WT and TK-/-livers,which regulate processes involved in hypoxia,proliferation,apoptosis and metabolism.One hour after ALF induction,WT livers exhibited increased cytokine expression compared to TK-/-livers,and after 4 hours,an induction of suppressor of cytokine signaling(SOCS) genes as well as JAK-STAT pathway activation were prominent in TK-/livers compared to controls.CONCLUSION:Our studies suggest a novel hepato-protective mechanism in Ron TK-/-mice wherein increased and sustained SOCS production and JAK-STAT activation in the hepatocyte may inhibit the destructive proinflammatory milieu and promote survival factors which blunt hepatic death and the ensuing development of ALF.Rishikesh M Kulkarni Louis W Kutcher William D Stuart Daniel J Carson Mike A Leonis Susan E Waltz 2012Hepatobiliary & Pancreatic Diseases International2012,11,4:3
2Preparation and Properties of Urethane/Acrylate Composite by Emulsion Polymerization Technique显示文摘Athawale V D Kulkarni M A 2009Prog Org Coat2009,,65:1
3查看详情显示文摘Humphry K J Kulkarni P M Weitz D A Morris J F Stone H A 0,,:1
4Progenitor cell-trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1显示文摘CERADINI D J KULKARNI A R CALLAGHAN M J 2004Nat Med2004,10,8:1
5Efficient lipase purification using reverse micellar extraction 显示文摘Gaikaiwari Raghavendra P Wagh Shipa A Kulkarni Bhaskar D 2012Biore-source Technology2012,108,:1
6Extraction and purifi-cation of tannase by reverse micelle system显示文摘Gaikaiwari R P Wagh S A Kulkarni B D 2012Separation andPurification Technology2012,,89:1
7Methylene blue dye iniection for identification of occult gastrointestinal bleeding显示文摘D' Mello A Sawant A D Kulkarni A 2014Indian J Gastroenterol2014,33,1:1
8Polyester Polyols for Water- borne Polyurethanes and Hybrid Dispersions 显示文摘Athawale V D Kulkarni M A 2010Prog Org Coat2010,67,1:1
9Fuzzy Neural Network Models for Supervised Classification:Multi-spectral Image Analysis显示文摘Kulkarni A D Lulla K 1999GeocartoInternational1999,14,4:1
10Optical coherence tomography and microscopy in gastrointestinal tissues显示文摘 Kulkarni M D Wang H W 1996IEEE J Quantum Electron1996,2,4:1
11Insecticidal toxicity against spiraling whitefly,Aleurodicus disperses Russell on Acalypha显示文摘Kambrckar D N Awaknavar J S Kulkarni K A 2003Journal of entomology research2003,27,1:1
12A review of process plan- ning techniques in layered manufacturing 显示文摘Kulkarni P Marsan A Dutta D 2000Rapid Prototy- ping Journal2000,6,1:1
13Preparation and proper- ties of urethane/acrylate composite by emulsion polymeri- zation technique显示文摘Athawale V D Kulkarni M A 2009Progress in Organic Coating2009,65,3:1
14Transport of liquids using superhydrophobic aerogels显示文摘Rao A V Kulkarni M M Bhagat S D 2005J Colloid Interf Sci2005,285,1:1
15Enhancement techniques for landuse analysis显示文摘Rao K R Kulkarni A D Chennaiah G Ch 1982Journal of the Indian Society of Remote Sensing1982,10,3:1
16Microemulsions as media for organic synthesis selective nitration of phenol to ortho - nitrophenol using dilute nitric acid 显示文摘CHHATER A S JOSHI R A KULKARNI B D 1993Jounlal of Colloid and Interface Science1993,158,1:1
17Superhydrophobic silica aerogels based on methyltrimethoxysilane precursor显示文摘Rao A V Kulkarni M M Amalnerkar D P 2003J Non-Crystalline Solids2003,330,13:1
18Transport of liquids using superhydrophobic aerogels显示文摘Rao A V Kulkarni M M Bhagat S D 2005Journal of Colloidand Interface Science2005,285,1:1
19Microemulsions as media for organic synthesis:Selective nitration of phenol to ortho-nitrophenol using dilute nitric acid显示文摘CHHATRE A S JOSHI R A KULKARNI B D 1993Colloid Interf Sci1993,158,:1
20Progenitor cell trafficking is regulated by hypoxic gradientsthrough HIF-1 induction of SDF-1 显示文摘Ceradini D J Kulkarni A R Callaghan M J 2004Nat Med2004,10,8:1
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