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| 1 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 2 | Old friends,new faces:Motivation research in the 1990s显示文摘 | Ambrose M L Kulik C T | 1999 | Journal of Management1999，25，： | 1 |
| 3 | Known by the company we keep: Stigma-by- association effects in the workplace显示文摘 | Kulik C T | 2008 | Academy of Management Review2008，33，21： | 1 |
| 4 | Work design as an approach to person-environment fit显示文摘 | Kulik C T Oldman G R and Hackman J R | 1987 | Journal of Voca- tional Behavior1987，31，3： | 1 |
| 5 | Old friend,new faces:motivation research in the 1990s显示文摘 | Ambrose M L Kulik C T | 1999 | Journal of Management1999，25，3： | 1 |
| 6 | Individual and corporate dispute resolution: Using procedural fairness as a deci- sion heuristic 显示文摘 | LIND E A KULIK C T AMBROSE M | 1993 | Administrative Science Quarterly1993，38，2： | 1 |
| 7 | Job Embeddedness in China:How HR Practices Impact Turnover Intentions显示文摘 | BAMBACAS M KULIK T C | 2013 | The International Journal of Human Resource Management2013，24，10： | 1 |
| 8 | Relations between situational factors and the comparative referents used by employees 显示文摘 | Oldham G R KuliK C T Stepina L P | 1986 | Academy of Management Journal1986，29，3： | 1 |
| 9 | Old friends,new faces:Motivation research in the 1990s显示文摘 | Ambrose M.L Kulik C T | | 0，，： | 1 |
| 10 | Influence of social comparisons on perceptions of organizational fairness显示文摘 | Ambrose M L Hadand L K Kulik C T | 1991 | Journal of Applied Psychology1991，76，2： | 1 |
| 11 | Known by the Company We Keep:Stigma-by-Association Effects in the Workplace显示文摘 | KULIK C T BAINBRIDGE H T J CREGAN C | 2008 | Academy of Management Review2008，33，1： | 1 |
| 12 | Old Friends,New Faces:Motivation Research in the 1990s 显示文摘 | AmbroseM L & Kulik C T | 1999 | Journal ofManagement1999，25，3： | 1 |
| 13 | Job embeddedness in Chi- na: How HR practices impact turnover intentions显示文摘 | Bambacas M Kulik T C | 2013 | International Journal of Human Resource Manage- ment2013，24，10： | 1 |
| 14 | Known by the company we keep: Stigma- by- association effects in the workplace 显示文摘 | Kulik C T Bainbridge H T J Cregan C | 2008 | Academy of Management Review2008，33，： | 1 |
| 15 | Personal and Situa- tional Determinants of Referent Choice 显示文摘 | KULIK C T AMBROSE M L | 1992 | Acade- my of Management Review1992，17，2： | 1 |
| 16 | Relations between Situational Factors and the Compara- tive Referents Used by Employees 显示文摘 | OLDHAM G R KULIK C T STEPINA L P | 1986 | Academy of Management Journal1986，29，59： | 1 |
| 17 | Assessing instructor cultural competence in the classroom: an instrument and a development process 显示文摘 | ROBERSON L KULIK C T PEPPER M B | 2002 | Journal of Management Education2002，6，1： | 1 |
| 18 | Hetero-Epitaxy of Perovskite Oxides on GaAs(001 ) by Molecular Beam Epitaxy 显示文摘 | Liang Y Kulik J Eschrich T C | 2004 | Applied Physics Letters2004，85，： | 1 |
| 19 | Hepatoeellular carcinoma reeurrance and death following living and deceased donor liver transplantation显示文摘 | Fisher R A Kulik L M Freise C E Lok A S Shearon T H Brown RS Jr | 2007 | AmJ Transplant2007，7，： | 1 |
| 20 | Ablation of metalsand semiconductors with ultrashort pulsed lasers:improving surfacequalities of microcuts and grooves显示文摘 | OSTENDORF A KULIK C BAUER T | 2004 | Proceedings of SPIE2004，5340，： | 1 |
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