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| 1 | Prognosis following transcatheter arterial embolization for 121 patients with unresectable hepatocellular carcinoma with or without a history of treatment显示文摘瞄准:回顾地为 HCC 后面的 transcatheter 与肝细胞癌(HCC ) 评估病人的预后与或没有治疗的历史动脉的 embolization (TAE ) 。方法:有在我们的医院里从 1992 ~ 2004 与 TAE 对待的 HCC 的 121 个病人在这研究被注册。84 个病人为 HCC 有治疗的历史,当时 37。在入口,有额外肝的转移的病人,门静脉肿瘤血栓,或孩子呸班的时候, C 被排除。当 HCC 的复发被提高的肿瘤标记,或 ultrasonography 或动态计算断层摄影术调查结果诊断时, TAE 被重复。结果:肿瘤尺寸更大,没有过去的治疗(P<0.01 ) ,肿瘤的数字是在病人的少数。然而,在节点转移(TNM ) 舞台或幸存在 2 个组之间评估的肿瘤没有差别。一个双性人 alpha-fetoprotein (法新社)(>100 ng/mL ) 的小叶片的肿瘤和高水平是与在有 HCC 的历史的病人的差的预后有关的因素。结论:预后追随者 TAE 在有或没有过去的治疗的 HCC 病人之间是类似的。在到一堂重复 TAE 功课的入口能改进预后以前, HCC 或周期性的 HCC 和获得的好本地人的早诊断对 HCC 控制。 | Atsushi Hiraoka Teru Kumagi Masashi Hirooka Takahide Uehara Kiyotaka Kurose Hidehito luchi Yoichi Hiasa Bunzo Matsuura Kojiro Michitaka Seishi Kumano Hiroaki Tanaka Yoshimasa Yamashita Norio Horiike Teruhito Mochizuki Morikazu Onji | 2006 | World Journal of Gastroenterology2006,12,13: | 9 |
| 2 | 近震源地震波波形资料反演震源破裂过程的可靠性分析显示文摘用近震源波形资料拟合反演地震的震源破裂过程 ,所包含的一些不确定因素将对反演结果的精度及可靠性产生影响 .文中的数值实验分析了所假定的反演断层模型参数的某些不确定性对反演结果的影响程度 ,并对观测波形的截取长度对反演精度的影响进行了讨论 .结果表明 :(1)近震源地震波形资料能较好地分辨断层浅部的破裂过程 .然而对断层深部的位错分布的约束和反演能力较差 .联合使用近、远场地震波资料进行反演 ,能反演出一个更为完全的整个断层破裂过程的图像 .(2 )用近震源地震波资料反演时 ,反演结果对所假定的反演断层的走向和倾角非常敏感 .断层走向偏离真实值 2°或倾角偏离真实值 5°都会导致一个虚假的反演结果 .(3)反演中所使用的介质速度结构模型的不确定性 ,也会对反演结果产生影响 . | 周仕勇 Kojiro Irikura | 2005 | 地球物理学报2005,48,1: | 8 |
| 3 | 胆道肿瘤临床实践指南(英文第三版)显示文摘日本肝胆胰外科学会(JSHBPS)于2007年出版第一版胆道肿瘤(胆管癌、胆囊癌及壶腹癌)临床实践指南,于2014年更新第二版,2021年英文第三版胆道肿瘤临床实践指南围绕6个主题提出若干临床问题,基于相关循证医学证据并组织专家讨论后,最终确定推荐意见、推荐强度以及推荐说明。根据证据推荐分级的评估、制订与评价(GRADE)系统,推荐强度被分为1级(强)或者2级(弱)。英文第三版胆道肿瘤临床实践指南中提出的31个临床问题涵盖:(1)预防性治疗;(2)诊断;(3)胆道引流;(4)外科治疗;(5)化疗;(6)放疗。31个临床问题中,14个问题给予推荐强度为强的推荐意见,14个问题给予推荐强度为弱的推荐意见,剩余的3个问题未给予推荐意见。每条推荐意见都进行推荐强度说明。最新版指南基于循证医学证据,为临床提供了重要建议。未来与癌症登记数据库协作将是评估指南和建立新证据的关键。 | Masato Nagino Satoshi Hirano Hideyuki Yoshitomi Taku Aoki Katsuhiko Uesaka Michiaki Unno Tomoki Ebata Masaru Konishi Keiji Sano Kazuaki Shimada Hiroaki Shimizu Ryota Higuchi Toshifumi Wakai Hiroyuki Isayama Takuji Okusaka Toshio Tsuyuguchi Yoshiki Hirooka Junji Furuse Hiroyuki Maguchi Kojiro Suzuki Hideya Yamazaki Hiroshi Kijima Akio Yanagisawa Masahiro Yoshida Yukihiro Yokoyama Takashi Mizuno Itaru Endo 杨翼飞(译) 仇毓东(译) 赵梦珂(译) 伏旭(译) 蔡正华(译) 毛凉(审校) | 2021 | 中华消化外科杂志2021,20,4: | 7 |
| 4 | 退火对Inconel 718合金氢脆特性的影响显示文摘通过实施不同的退火热处理工艺,调整合金中强化相的析出状态,制备具有不同退火状态的几组拉伸试样。对每组试样在未充氢和充氢后按相同的条件进行拉伸试验,通过比较未充氢试样和充氢后试样的强度和塑性,评价氢对该组试样的脆化作用。通过比较不同组试样的脆化表现,考察退火状态对Inconel718氢脆倾向的影响。试验结果表明,随着退火程度的加强,强化相体积分数减少,氢引起的塑性损失下降,即抗氢脆性能改善。该结果说明,强化相γ'和γ'对Intonel718合金的氢脆有促进作用。因此,根据不同工业应用要求,在符合强度要求的前提下,可以通过热处理改善零件的抗氢脆性能。 | 刘六法 卢晨 翟春泉 丁文江 Akio Hirose Kojiro F.Kobayashi | 2005 | 稀有金属材料与工程2005,34,6: | 7 |
| 5 | Prospective Cohort Study of Transarterial Chemoembolization for Unresectable Hepatocellular Carcinoma in 8510 Patients显示文摘 | Kenichi Takayasu Shigeki Arii Iwao Ikai Masao Omata Kiwamu Okita Takafumi Ichida Yutaka Matsuyama Yasuni Nakanuma Masamichi Kojiro Masatoshi Makuuchi Yoshio Yamaoka | 2006 | Gastroenterology2006,,2: | 5 |
| 6 | Unexpected metastasis of intraductal papillary neoplasm of the bile duct without an invasive component to the brain and lungs:A case report显示文摘BACKGROUND Despite an expanding number of studies on intraductal papillary neoplasm of the bile duct(IPNB),distant metastasis remains unexplained especially in cases of carcinoma in situ.In the present study,we report a rare and interesting case of IPNB without invasive components that later metastasized to lungs and brain.CASE SUMMARY A 69-year-old male was referred to our hospital due to suspected cholangiocarcinoma.Laboratory tests on admission reported a mild elevation of alkaline phosphatase,γ-glutamyl transpeptidase,and total bilirubin in serum.Endoscopic retrograde cholangiography revealed a filling defect in the common bile duct(CBD)extending to the left hepatic duct.Peroral cholangioscopy delineated a tumor in the CBD that had a papillary pattern.Multidetector computed tomography and magnetic resonance cholangiopancreatography detected partial blockage ot interlude in the CBD leading to cholestasis without evidence of metastasis.Therefore,a diagnosis of IPNB cT1N0M0 was established.Left hepatectomy with bile duct reconstruction was performed.Pathological examination confirmed an intraepithelial neoplasia pattern without an invasive component and an R0 resection achievement.The patient was monitored carefully by regular examinations.However,at 32 mo after the operation,a 26 mm tumor in the lungs and a 12 mm lesion in the brain were detected following a suspicious elevated CA 19-9 level.Video-assisted thoracoscopic surgery of left upper lobectomy and stereotactic radiotherapy are indicated.In addition to histopathological results,a genomic profiling analysis using whole exome sequencing subsequently confirmed lung metastasis originating from bile duct cancer.CONCLUSION This case highlights the important role of genomic profiling analysis using whole exome sequencing in identifying the origin of metastasis in patients with IPNB. | Nguyen Hai Nam Kojiro Taura Masashi Kanai Keita Fukuyama Norimitsu Uza Hirona Maeda Yojiro Yutaka Toyofumi F Chen-Yoshikawa Manabu Muto Shinji Uemoto | 2020 | World Journal of Gastroenterology2020,26,3: | 5 |
| 7 | Recurrence of autoimmune hepatitis after liver transplantation without elevation of alanine aminotransferase显示文摘It is controversial whether steroid therapy should be continued to prevent the recurrence of autoimmune hepatitis(AIH)in patients who have undergone liver transplantation(LTx)due to AIH.We report a case of recurrent autoimmune hepatitis after LTx despite a persistently normal range of alanine aminotransferase(ALT).A 50-year-old woman was admitted to our hospital because of jaundice and severe liver dysfunction,where she was diagnosed with liver failure due to AIH.Steroid therapy was not effective enough and the patient received living-donor LTx in 1999.Following the operation,the level of ALT was maintained within a normal range and anti-nuclear antibody(ANA)became negative,however,the serum level of IgG gradually elevated and ANA became positive,while platelets decreased.A liver biopsy performed 6 years after LTx showed histological findings of AIH and she was diagnosed with recurrent AIH.A recurrence of AIH may occur after LTx even if the level of ALT remains within a normal range.We consider that a protocol liver biopsy should be performed in patients who undergo LTx due to AIH to decide the indication for steroid therapy. | Huaiqi Yao Kojiro Michitaka Yoshio Tokumoto Yosuke Murata Toshie Mashiba Masanori Abe Yoichi Hiasa Norio Horiike Morikazu Onji | 2007 | World Journal of Gastroenterology2007,13,10: | 3 |
| 8 | Hepatic Stellate Cells Secrete Angiopoietin 1 That Induces Angiogenesis in Liver Fibrosis显示文摘 | Kojiro Taura Samuele De Minicis Ekihiro Seki Etsuro Hatano Keiko Iwaisako Christoph H. Osterreicher Yuzo Kodama Kouichi Miura Iwao Ikai Shinji Uemoto David A. Brenner | 2008 | Gastroenterology2008,,5: | 3 |
| 9 | Expression and function of interleukin-8 in human hepatocellular carcinoma显示文摘 | Jun Akiba Hirohisa Yano Sachiko Ogasawara Koichi Higaki M. Kojiro | 2001 | International Journal of Oncology2001,,2: | 2 |
| 10 | Microvascular Invasion in Patients with Hepatocellular Carcinoma and Its Predictable Clinicopathological Factors显示文摘 | Shuji Sumie MD Ryoko Kuromatsu MD Koji Okuda MD Eiji Ando MD Akio Takata MD Nobuyoshi Fukushima MD Yasutomo Watanabe MD Masamichi Kojiro MD Michio Sata MD | 2008 | Annals of Surgical Oncology2008,,5: | 2 |
| 11 | Prognostic Index for Patients with Hepatocellular Carcinoma Combined with Tumor Thrombosis in the Major Portal Vein显示文摘 | Iwao Ikai Etsuro Hatano Suguru Hasegawa Hideaki Fujii Kojiro Taura Naoki Uyama Yasuyuki Shimahara | 2006 | Journal of the American College of Surgeons2006,,3: | 2 |
| 12 | Angiosarcoma of the scalp diagnosed by the presence of neck inflammation:a case report显示文摘Angiosarcoma is an uncommon malignancy,which spread out from the endothelial cells of vessels.Scalp angiosarcoma with cervical lymph node metastasis is particularly rare.This article describes a rare case of angiosarcoma of the scalp,presenting as neck inflammation.Imaging procedures such as computed tomography(CT),magnetic resonance image(MRI) and ultrasonography(US) were not sufficient to diagnose this case.A needle biopsy provided an effective and accurate diagnosis of cervical lymph node metastasis.Additional observation and physical examination was required to diagnose the origin of the primary cancerous lesion.Once the angiosarcoma diagnosis was confirmed histologically,sequential weekly and monthly docetaxel(DTX) treatment was effective in preventing reoccurrence.Nonetheless,the optimization of angiosarcoma treatment remains a future goal.Although patients generally describe pain and swelling at the primary lesion site,this patient complained only of painful neck inflammation,without any indication of pain or swelling of the scalp.A revised diagnostic protocol should note that cervical lymph node metastasis of unknown primary origin may result from angiosarcoma of the scalp. | Rei Karube Hiroyoshi Sasaki Keiji Shinozuka Yasuhiro Fujisawa Toru Yanagawa Kenji Yamagata Kojiro Onizawa Fujio Otsuka Hiroki Bukawa | 2012 | International Journal of Oral Science2012,4,3: | 2 |
| 13 | The MicroRNA-21/PTEN Pathway Regulates the Sensitivity of HER2-Positive Gastric Cancer Cells to Trastuzumab显示文摘 | Kojiro Eto Masaaki Iwatsuki Masayuki Watanabe Satoshi Ida Takatsugu Ishimoto Shiro Iwagami Yoshifumi Baba Yasuo Sakamoto Yuji Miyamoto Naoya Yoshida Hideo Baba | 2014 | Annals of Surgical Oncology2014,,1: | 2 |
| 14 | Report of the 15th follow-up survey of primary liver cancer显示文摘 | Iwao Ikai Yuji Itai Kiwamu Okita Masao Omata Masamichi Kojiro Kenichi Kobayashi Yasuni Nakanuma Shunji Futagawa Masatoshi Makuuchi Yoshio Yamaoka | 2003 | Hepatology Research2003,,1: | 2 |
| 15 | Pathomorphologic study on the mechanism of fatty change in small hepatocellular carcinoma of humans显示文摘 | Rumiko Kutami Yutaka Nakashima Osamu Nakashima Koji Shiota Masamichi Kojiro | 2000 | Journal of Hepatology2000,,2: | 2 |
| 16 | Recurrence of hepatocellular carcinoma: multicentric occurrence or intrahepatic metastasis? A viewpoint in terms of pathology显示文摘 | Osamu Nakashima Masamichi Kojiro | 2001 | Journal of Hepato - Biliary - Pancreatic Surgery2001,,5: | 2 |
| 17 | A case-control study for clinical and molecular biological differences between hepatitis B viruses of genotypes B and C显示文摘 | Etsuro Orito Masashi Mizokami Hiroshi Sakugawa Kojiro Michitaka Kazuyoshi Ishikawa Takafumi Ichida Takeshi Okanoue Hiroshi Yotsuyanagi Shiro Iino | 2001 | Hepatology2001,,1: | 2 |
| 18 | Expression of Matrix Metalloproteinase-7 on Cancer Cells and Tissue Endothelial Cells in Renal Cell Carcinoma: Prognostic Implications and Clinical Significance for Invasion and Metastasis显示文摘 | Yasuyoshi Miyata Takahisa Iwata Kojiro Ohba | 2006 | Clin Cancer Res2006,12,23: | 1 |
| 19 | Histopathologic evaluation of hepatocellular carcinoma with special reference to small early stage tumors显示文摘 | Kojiro M Nakashima O | 1999 | Semin Liver Dis1999,19,3: | 1 |
| 20 | Evidence-based risk factors for seroma formation in breast surgery显示文摘 | Katsumasa Kuroi Kojiro Shimozuma Tetsuya Taguehi | 2006 | Jpn J Clin Oncol2006,36,: | 1 |