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| 1 | 用RFLP方法研究陕西省主要小麦品种遗传多样性及其演变显示文摘研究用RFLP方法,对我国主要小麦产区,陕西省40年代以来广为种植的小麦品种的遗传多样性进行了研究,结果表明,占总带数26.2%的HINDII酶的RFLP带具有遗传多态性。24个小麦品种平均遗传相似系数为0.948。53.8%的探针显示了多态性。平均多态性信息含量指数为0.252。陕西省小麦品种遗传多样性以70年代为最高,之后开始降低。 | 朱列层 唐国顺 HAZEN S P KIM H S WARD R W | 1999 | 西北植物学报1999，19，2： | 11 |
| 2 | Tenascin C upregulates interleukin-6 expression in human cardiac myofibroblasts via toll-like receptor 4显示文摘AIM:To investigate the effect of Tenascin C(TNC)on the expression of pro-inflammatory cytokines and matrixmetalloproteinases in human cardiac myofibroblasts(CMF).METHODS:CMF were isolated and cultured from patients undergoing coronary artery bypass grafting.Cultured cells were treated with either TNC(0.1μmol/L,24 h)or a recombinant protein corresponding to different domains of the TNC protein;fibrinogen-like globe(FBG)and fibronectin typeⅢ-like repeats(TNⅢ5-7)(both 1μmol/L,24 h).The expression of the proinflammatory cytokines;interleukin(IL)-6,IL-1β,TNFαand the matrix metalloproteinases;MMPs(MMP1,2,3,9,10,MT1-MMP)was assessed using real time RT-PCR and western blot analysis.RESULTS:TNC increased both IL-6 and MMP3(P<0.01)mR NA levels in cultured human CMF but had no significant effect on the other markers studied.The increase in IL-6 mR NA expression was mirrored by an increase in protein secretion as assessed by enzymelinked immunosorbant assay(P<0.01).Treating CMF with the recombinant protein FBG increased IL-6mR NA and protein(P<0.01)whereas the recombinant protein TNⅢ5-7 had no effect.Neither FBG nor TNⅢ5-7 had any significant effect on MMP3 expression.The expression of toll-like receptor 4(TLR4)in human CMF was confirmed by real time RT-PCR,western blot and immunohistochemistry.Pre-incubation of cells with TLR4neutralising antisera attenuated the effect of both TNC and FBG on IL-6 mR NA and protein expression.CONCLUSION:TNC up-regulates IL-6 expression in human CMF,an effect mediated through the FBG domain of TNC and via the TLR4 receptor. | Azhar Maqbool Emma J Spary Iain W Manfield Michaela Ruhmann Lorena Zuliani-Alvarez Filomena O Gamboa-Esteves Karen E Porter Mark J Drinkhill Kim S Midwood Neil A Turner | 2016 | World Journal of Cardiology2016，8，5： | 4 |
| 3 | Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial显示文摘 | Craig S Anderson Yining Huang Ji Guang Wang Hisatomi Arima Bruce Neal Bin Peng Emma Heeley Christian Skulina Mark W Parsons Jong Sung Kim Qing Ling Tao Yue Chun Li Jian Dong Jiang Li Wen Tai Jin Li Zhang En Xu Yan Cheng Stephane Heritier Lewis B Morgenste | 2008 | Lancet Neurology2008，，5： | 4 |
| 4 | 干骺端固定解剖型非骨水泥柄结合陶瓷对陶瓷全髋关节置换治疗30岁以下患者的临床结果显示文摘年轻患者全髋关节置换手术方式还存在争议。作者分析了96例(127髋)30岁以下患者采用干骺端固定解剖型非骨水泥柄结合陶瓷对陶瓷全髋关节置换的治疗结果。随访10~16年,Harris评分、WOMAC评分、UCLA评分分别为95、16、8分。手术1年后,没有发生疼痛,所有股骨柄均未发现松动。无关节异响、陶瓷碎裂、松动以及骨溶解等并发症。因此作者认为, | Kim Y H Park J W Kim J S 胡孔足 | 2012 | 临床骨科杂志2012，15，5： | 3 |
| 5 | Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study显示文摘 | Mark S Pearce Jane A Salotti Mark P Little Kieran McHugh Choonsik Lee Kwang Pyo Kim Nicola L Howe Cecile M Ronckers Preetha Rajaraman Alan W Craft Louise Parker Amy Berrington de González | 2012 | The Lancet . 2012 (9840)2012，，： | 3 |
| 6 | Growth factors for fetal and adult human astrocytes in culture显示文摘 | Yong V W Kim S U Pleasure D E | 1998 | Brain Res1998，444，1： | 2 |
| 7 | 血根碱对肉鸡生长性能、相对器官重量、盲肠菌群、血清胆固醇水平以及肉品质的影响显示文摘研究旨在探索日粮添加血根碱(SGV)对肉鸡生长性能、相对器官重量、盲肠菌群、血清胆固醇水平和腿肌丙二醛含量的影响。选用840日龄雄性肉鸡(罗斯品种)饲养于28个稻草垫上,随机分为4个处理:玉米-豆粕型基础对照日粮、基础日粮中添加卑霉素10 ppm作为生长促进剂(AGP)、基础日粮中添加SGV 20 ppm(SGV20)和50 ppm(SGV50)。与饲喂基础日粮的肉鸡相比,基础日粮中添加AGP组、SGV20组和SGV50组的肉鸡最终体重(BW)、日增重、饲料转化率(FCR)显著改善(P<0.05)。与对照组相比,SGV20喂养组的肉鸡相对空肠重量显著降低(P<0.05),所有添加SGV组肉鸡相对空肠或回肠长度显著升高(P<0.05)。SGV20组较对照组肉鸡肠道菌群有所改变,尤其是盲肠乳酸菌数增加,但AGP组无改变。SGV20组或SGV50组肉鸡的总胆固醇水平较对照组显著降低(P<0.05),控制饮食物显著降低(P<0.05)。添加SGV后,作为脂质过氧化反应指示剂的腿肌丙二醛含量显著降低(P<0.05)。研究表明,在肉鸡日粮中补充SGV 20或50 ppm可以提高肉鸡生长性能,改变多种生物和生理参数,如相对器官重量、血清胆固醇水平、肠道菌群和肉品质。 | Lee K W Kim J S Oh S T Kang C W An B K | 2015 | 饲料博览2015，0，3： | 2 |
| 8 | Superplasticity in Thin Magnesium Alloy Sheet and Detormation Mechanism Maps for Magnesium Alloys at Elevated Temperatures显示文摘 | Kim W J Chung S W Kum D | 2001 | Acta Mater2001，，49： | 2 |
| 9 | Expansion of Active Site Area and Improvement of Kinetic Reversibility in Electrochemical Pseudocapacitor Electrode显示文摘 | Lee H Y Kim S W | 2001 | Electrochemical and Solid-state Letters2001，4，3： | 2 |
| 10 | A new motor speed estimation using Kalman filter in low -speed range显示文摘 | Kim H W Sul S K | 1996 | IEEE Trans on Industrial Electronics1996，43，4： | 2 |
| 11 | Muscarinic regulation of pacemaker frequency in murine gastric interstitial cells of Cajal显示文摘 | Kim T W Koh S D Ordog T | 2003 | J Physil2003，546，2： | 2 |
| 12 | 分子束外延高Mg掺杂GaN的发光特性显示文摘采用分子束外延技术在蓝宝石衬底上制备Mg掺杂的立方相p-GaN,并对其不同温度下的光致发光光谱进行了研究.实验观察到高Mg掺杂GaN中施主受主对发光的反常温度行为.理论分析表明,高Mg掺杂GaN中施主受主对的发光受到陷阱与受主间竞争俘获非平衡空穴过程和空穴隧穿输运过程的影响. | 宋航 Park S H Kang T W Kim T W | 1999 | 发光学报1999，20，2： | 2 |
| 13 | Formation characteristics of nitric oxide in a three-staged air/LPG flame显示文摘 | Kim H S Baek S W Yu M J | 2003 | International Journal of Heat and Mass Transfer2003，46，： | 2 |
| 14 | The effect of pre-irradiation dose intense CHOP on anthracyline resistance in localized nasal NK/ T-cell lymphoma显示文摘 | Lee S H Ahn Y C Kim W S | 2006 | Haematologica2006，91，3： | 1 |
| 15 | Multiple doubly periodic solutions of semilinear dissipative hyperbolic equations显示文摘 | Kim W S | 1996 | J Math Anal Appl1996，197，2： | 1 |
| 16 | Diagnostic value of procalcitonin and C-reactive protein in differentiation of pleural effusion 显示文摘 | Kim S H Kim S T Kim C W | 2007 | Chest2007，132，4： | 1 |
| 17 | On utilizing search methods to select subspace dimensions for kernel-based nonlinear subspaceclassifiers显示文摘 | Kim S W Onmmen B J | 2005 | IEEE Trans Patt Anal Mach Intell2005，27，： | 1 |
| 18 | Low-copy plasmids can perform as weU as or better than high-copy plasmids for metabolic engineering of bacteria 显示文摘 | Jones K L Kim S W Keasling J D | 2000 | Metabolic Engineering2000，2，： | 1 |
| 19 | Antioxidant capacity of phenolic phytochemicals from various cultivars of plums显示文摘 | KIM D O JEONG S W LEE C Y | 2003 | Food Chem2003，81，： | 1 |
| 20 | A new class of SN2 reactions catalyzed by protic solvents: facile fluorination for isotopic labeling of diagnostic molecules 显示文摘 | Kim D W Ahn D S Oh Y H | 2006 | J Am Chem Soc2006，128，16： | 1 |
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