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| 1 | Understanding prostate-specific antigen dynamics in monitoring metastatic castration-resistant prostate cancer: implications for clinical practice显示文摘象为变形阉割抵抗的前列腺癌症(CRPC ) 的 docetaxel 和 cabazitaxel 治疗一样的新奇神经质的治疗的可获得性在没有前进的幸存和全面幸存与改进为这组病人改变了眼界。医生们经常用浆液诊断前列腺癌症的前进前列腺特定的抗原(PSA ) 。然而,浆液 PSA 总是没在 CRPC 与临床的地位被相关。与更大的精确评估 PSA 动力学, PSA 并且 CRPC 的开发的机制的控制的理解被需要。而且,与最佳地改进预后和病人的 QOL 的适当预定使用新神经质的治疗是必要的。在现在的评论,我们查明 PSA 动力学和 CRPC 的发展的机制为 mCRPC 在新治疗的最佳的利用帮助。 | Atsushi Mizokami Kouji Izumi Hiroyuki Konaka Yasuhide Kitagawa Yoshifumi Kadono Kazutaka Narimoto Takahiro Nohara Amit K Bahl Mikio Namiki | 2017 | Asian Journal of Andrology2017，19，2： | 5 |
| 2 | Endoscopic retrograde cholangiopancreatography for bile duct stones in patients with a performance status score of 3 or 4显示文摘BACKGROUND As the aging population grows worldwide,the rates of endoscopic retrograde cholangiopancreatography(ERCP)for common bile duct stones(CBDS)in older patients with a poor performance status(PS)have been increasing.However,the data on the safety and efficacy of ERCP for CBDS in patients with a PS score of 3 or 4 are lacking,with only a few studies having investigated this issue among patients with poor PS.AIM To examine the safety and efficacy of ERCP for CBDS in patients with a PS score of 3 or 4.METHODS This study utilized a retrospective multi-centered design of three institutions in Japan for 8 years to identify a total of 1343 patients with CBDS having native papillae who underwent therapeutic ERCP.As a result,1113 patients with a PS 0-2 and 230 patients with a PS 3-4 were included.One-to-one propensity-score matching was performed to compare the safety and efficacy of ERCP for CBDS between patients with a PS 0-2 and those with a PS 3-4.RESULTS The overall ERCP-related complication rates in all patients and propensity score-matched patients with a PS 0-2 and 3-4 were 9.0%(100/1113)and 7.0%(16/230;P=0.37),and 4.6%(9/196)and 6.6%(13/196;P=0.51),respectively.In the propensity score-matched patients,complications were significantly more severe in the group with a PS 3-4 than in the group with a PS 0-2 group(P=0.042).Risk factors for complications were indications of ERCP and absence of antibiotics in the multivariate analysis.Therapeutic success rates,including complete CBDS removal and permanent biliary stent placement,in propensity score-matched patients with a PS 0-2 and 3-4 were 97.4%(191/196)and 97.4%(191/196),respectively(P=1.0).CONCLUSION ERCP for CBDS can be effectively performed in patients with a PS 3 or 4.Nevertheless,the indication for ERCP in such patients should be carefully considered with prophylactic antibiotics. | Hirokazu Saito Yoshihiro Kadono Takashi Shono Kentaro Kamikawa Atsushi Urata Jiro Nasu Haruo Imamura Ikuo Matsushita Tatsuyuki Kakuma Shuji Tada | 2022 | World Journal of Gastrointestinal Endoscopy2022，14，4： | 2 |
| 3 | Decreasing trend in prostate cancer with high serum prostate-specific antigen levels detected at first prostate-specific antigen-based population screening in Japan显示文摘在前列腺特定的抗原(PSA ) 澄清最近的趋势在在日本的人的分发,我们分析了经历基于 PSA 的人口屏蔽的人的 PSA 分布。我们总结了基于 PSA 的人口在 Kanazawa 屏蔽的年度单个数据,日本从 2000 ~ 2011,并且在屏蔽的第一张人口的参加者的分析基线浆液 PSA 值。浆液 PSA 分布根据年龄在所有参加者和那些排除的前列腺癌症病人被估计。从 2000 ~ 2011, 19 620 个人在这个屏蔽节目参与年老的 54-69 岁。在首先屏蔽的所有参加者的吝啬的基线浆液 PSA 水平是在 2000 的 2.64 ng ml −1 ,并且逐渐地在 2006 减少了到约 1.30 ng ml −1 。排除前列腺癌症病人的参加者的是在 2000 的 1.46 ng ml −1 ,并且在学习时期期间没有显著变化。95 在排除在人屏蔽的第一张人口检测的前列腺癌症病人的参加者的 th 百分位数变老 54-59, 60-64,和 65-69 岁分别地是 2.90, 3.60,和 4.50 ng ml −1, 。在人口屏蔽的开始以后,有高浆液 PSA 层次的前列腺癌症病人的比例减少了。然而,没有前列腺癌症,在在人的浆液 PSA 层次没有变化。没有在日本的前列腺癌症的人的年龄特定的 PSA 参考水平在中国和朝鲜类似于那。 | Yasuhide Kitagawa Kazuaki Machioka Hiroshi Yaegashi Kazufumi Nakashima Mitsuo Ofud Kouji Izumi Satoru Ueno Yoshifumi Kadono Hiroyuki Konaka Atsushi Mizokami Mikio Namiki | 2014 | Asian Journal of Andrology2014，16，6： | 2 |
| 4 | Reversible control of silver nanoparticle generation and dissolution in soda-lime silicate glass through X-ray irradiation and heat treatment显示文摘 | CHEN S AKAI T KADONO K | 2001 | Appl Phys Lett2001，79，22： | 2 |
| 5 | Nanosized gold clusters formation in selected areas of soda-lime silicate glass 显示文摘 | SHENG J KADONO K YAZAWA T | 2003 | J Non-Cryst Solids2003，324，： | 2 |
| 6 | The role of the epidermal endothelin cascade in the hyperpigmentation mechanism of lentigo senilis 显示文摘 | KADONO S MANAKA I KAWASHIMA M etal | 2001 | J Invest Dermatol2001，4，： | 1 |
| 7 | New energy efficient processes and newly developed absorbents for flue gas CO2 capture显示文摘 | Kadono K Suzuki A Iijima M | 2013 | Energy Procedia2013，37，： | 1 |
| 8 | A functional role for circulating mouse Lselectin in regu lating leukocyte/endothelial cell interactions in vivo显示文摘 | Tu L Poe JC Kadono T | 2002 | J Immunol2002，169，4： | 1 |
| 9 | Increased serum soluble CD147 levels in patients with systemic sclerosis: association with scleroderma renal crisis显示文摘 | Koichi Yanaba Yoshihide Asano Yayoi Tada Makoto Sugaya Takafumi Kadono Yasuhito Hamaguchi Shinichi Sato | 2012 | Clinical Rheumatology2012，，5： | 1 |
| 10 | Glass formation,physico-chemical properties,and structure of glasses based on Ga2S3-GeS2-Sb2S3 system显示文摘 | Ichikawa M Wakasugi T Kadono K | 2010 | J Non Cryst Solids2010，356，43： | 1 |
| 11 | Production of a 100 m-long high-quality graphene transparent conductive film by roll-to-roll chemical vapor deposition and transfer process显示文摘 | KOBAYASHI T BANDO M KIMURA N SHIMIZU K KADONO K UMEZU N MIYAHARA K HAYAZAKI S NAGAI S MIZUGUCHI Y MURAKAMI Y HOBARA D | 2013 | Applied Physics Letters2013，102，02： | 1 |
| 12 | Effects of light quality on leaf morphogenesis of a heterophyllous amphibious plant,Rotala hippuris显示文摘 | Momokawa N Kadono Y Kudoh H | | 0，，： | 1 |
| 13 | Osteoimmunology: interplay between the immune system and bone metabolism显示文摘 | Walsh MC Kim N Kadono Y | 2006 | Annu Rev Immunol2006，24，： | 1 |
| 14 | New Energy Effi- cient Processes and Improvements for Flue Gas CO2 Cap- ture显示文摘 | TATSUMI M YAGI Y KADONO K | 2011 | Energy Procedia2011，4，： | 1 |
| 15 | Stereoselective renal tubular secretion of an organic anion in the isolated perfused rat kidney显示文摘 | Higaki K Kadono K Goto S | 1994 | J Pharmacol Exp Ther1994，270，： | 1 |
| 16 | Axin localizes to the centrosome and is involved in microtubule nucleation显示文摘 | Fumoto K Kadono M Izumi N | | 0，，06： | 1 |
| 17 | Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis 显示文摘 | Kobayashi N Kadono Y Naito A | 2001 | EMBO J2001，20，6： | 1 |
| 18 | IL-1 regulates cytoskeletal organization in osteoclasts via TNF receptor-associated factor 6/c-Src complex显示文摘 | Nakamura I Kadono Y Takayanagi H | | 0，，10： | 1 |
| 19 | Growth regulation in scleroderma fibroblasts: increased response to transforming growth factor-beta 1 显示文摘 | Kikuchi K Kadono T Ihn H | 1995 | J Invest Dermatol1995，105，1： | 1 |
| 20 | Transformation of epithelial MadinDarby canine kidney cells with p60-src induced expression of mambrinetype 1 matrix metalloproteinase and invasiveness 显示文摘 | Kadono Y Okada Y Namiki M | 1998 | Cancer Res1998，58，10： | 1 |
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