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1Genome-scale reconstruction and in silico analysis of the clostridium acetobutylicum ATCC 824 metabolic network显示文摘Lee Joungmin Yun Hongseok Lee Sang Yup 0,,05:1
2Chorioamnionitis caused by Serratia marcescens in a healthcare worker: A case report显示文摘BACKGROUND Healthcare workers(HCWs)are at an increased risk for exposure to infections.Serratia marcescens(S.marcescens)is a gram-negative,opportunistic and nosocomial pathogen belonging to the Enterobacterieae family.A few case reports have been published of chorioamnionitis caused by S.marcescens infection.Immunological changes during pregnancy can also affect the risk of infection.However,few studies have examined hospital-acquired bacterial infection in pregnant HCWs.CASE SUMMARY A 33-year-old woman,a resident in anesthesiology,was admitted at 14 wk gestation for fever with chills.She had no medical history other than contact dermatitis of both hands that started from the beginning of the trainee.There was no obvious infection focus and no bacterial growth in blood cultures.She was discharged after 1 wk of empirical antibiotic treatment.At three weeks before the fever started,she had a blister on the site of contact dermatitis on both hands,she applied antibiotic ointment for three days and the blisters had healed.At 19 wk gestation,she had a high fever and was readmitted.Physical examination and image studies were nonspecific and the patient had no other symptoms.S.marcescens grew in blood cultures at 19 wk gestation.Treatment with intravenous antibiotics was started.However,she suffered a miscarriage at 224/7 wk gestation.Pathologically,the amniotic membrane showed chorioamnionitis with a focal infarct.Subsequently,a placenta tissue culture grew S.marcescens.CONCLUSION HCWs can be exposed to pathogens that can cause opportunistic infections such as S.marcescens.Pregnancy affects the immune system,making it susceptible to opportunistic infections.Therefore,pregnant HCWs may require more preventive measures,including hand hygiene and avoid risk factors(ex.wrapping the skin).Sue Youn Park Min Ji Kim Sanghee Park Nah Ihm Kim Hyung Hoon Oh Joungmin Kim 2021World Journal of Clinical Cases2021,9,20:1
3Genome-scale reconstruction and in silico analysis of the Clostridium acetobutylicum ATCC 824 metabolic network显示文摘Joungmin L Hongseok Y Adam M 2008Appl Microbiol Biotechnol2008,,80:1
4Different intraoperative decisions for undiagnosed paraganglioma:Two case reports显示文摘BACKGROUND Paragangliomas may be preoperatively misdiagnosed as non-functioning retroperitoneal tumors and are sometimes suspected only at the time of intraoperative manipulation.Without preoperative alpha blockade preparation,a hypertensive crisis during tumor manipulation and hypotension after tumor removal may result in critical consequences.Therefore,primary consideration should be given to the continuation or discontinuation of surgery on the basis of the possibility of gentle surgical manipulation and hemodynamic stabilization.We report two cases of paragangliomas detected intraoperatively.CASE SUMMARY A 65-year-woman underwent laparoscopic small-bowel wedge resection.A hypertensive crisis occurred during manipulation of the mass,and an unrecognized catecholamine-producing paraganglioma was suspected.The surgeon and anesthesiologists believed that tumor excision could be performed with minimal manipulation of the tumor because the tumor was in a favorable location.Serious hemodynamic instability did not occur with aggressive use of vasoactive drugs.A week later,a 54-year-man underwent open resection of a 3-cm-sized retroperitoneal mass and showed the same findings during mass manipulation.For this patient,continuous manipulation of the mass seemed inevitable due to adhesion between the right adrenal gland and the mass in a narrow surgical field.The surgeon and anesthesiologists decided to cancel the surgical procedure and planned to perform a reoperation after alpha blockade therapy.Two weeks later,the tumor was uneventfully removed with small doses of vasoactive drugs.CONCLUSION When an undiagnosed paraganglioma is suspected intraoperatively,reoperation after adequate preparation should be considered as an option to avoid fatal outcomes.Dongho Kang Bo-eun Kim Minjae Hong Joungmin Kim Seongtae Jeong Seongheon Lee 2022World Journal of Clinical Cases2022,10,30:0
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