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| 1 | Alcohol dehydrogenase: A potential new marker for diagnosis of intestinal ischemia using rat as a model显示文摘AIM: Intestinal ischemia (Ii) is an abdominal emergency due to blockade of the superior mesenteric artery resulting in 60-100% mortality if diagnosed late. Changes in several biochemical parameters such as D (-)-lactate, Creatinine kinase isoenzymes and lactate dehydrogenase suggested for early diagnosis, lack specificity and sensitivity. Therefore a biochemical parameter with greater sensitivity needs to be identified.METHODS: Wistar male rats were randomly assigned into two groups; control sham operated (n = 24) and ischemic test (n = 24) group. Superior mesenteric arterial occlusion was performed in the ischemic test group for 1 h. Alcohol dehydrogenase (ADH) was estimated in blood from portal vein, right ventricle of heart, dorsal aorta (DA) and inferior vena cava (IVC). The Serum glutamic acid pyruvate transaminase (SGPT) was also estimated in blood from portal vein and right ventricle of heart.RESULTS: A significant increase (P<0.001) in the levels of ADH in both portal blood as well as heart blood of the test group (232.72±99.45 EU and 250.85±95.14 EU, respectively)as compared to the control group (46.39±21.69 EU and 65.38±30.55 EU, respectively) were observed. Similarly,increased levels of ADH were observed in blood samples withdrawn from DA and IVC in test animals (319.52±80.14EU and 363.90±120.68 EU, respectively) as compared to the control group (67.68±63.22 EU and 72.50±58.45 EU,respectively). However, in test animals there was significant increase in SGPT in portal blood (P = 0.054) without much increase in heart blood.CONCLUSION: Significant increase in the levels of ADH in portal and heart blood within 1 h of SMA occlusion without increase in SGPT in heart blood, suggests that the origin of ADH is from ischemic intestine and not from liver. Similarly, raised ADH levels were found in DA and IVC as well. IVC blood does represent peripheral blood sample. A raised level of ADH in test animals confirms it to be a potential marker in the early diagnosis of Ii. | Upendra R Gumaste Mukund M Joshi Devendra T Mourya Pradip V Barde Ghanshyam K Shrivastav Vikram S Ghole | 2005 | World Journal of Gastroenterology2005，11，6： | 9 |
| 2 | Perturbation of Wood Cellulose Synthesis Causes Pleiotropic Effects in Transgenic Aspen显示文摘在树上的纤维素生合成的基因操作可以提供新奇卓见进树的生长和发展。探索这可能性,一棵白杨的 overexpression 第二等的联系墙的纤维素 synthase (PtdCesA8 ) 基因在转基因的白杨(Populus tremuloides L.) 被尝试并且出人意料地象它的内长的对应物一样导致了 transgene 的 silencing。转基因的白杨植物的主要的轴快速停止成长,并且弱树枝采用了一个哭泣的生长习惯。而且,转基因的植物开始开发了更小的叶子和一个不太广泛的根系统。几乎没象 10% 纤维素一样包含的转基因的白杨植物的第二等的木部(木头) 使正常化与典型地在正常白杨木头发现的 41% 纤维素相比弄干重量。在纤维素的这巨大的减小被木质素(35%) 和非有纤维质的多糖(55%) 的比例的增加在控制植物与 22% 木质素和 36% 非有纤维质的多糖相比伴随。生产的转基因的茎典型崩溃或改变了第二等的墙形态学并且极大地包含了的不规则的木部容器减少了水晶的纤维素的数量。这些结果在维持要求在树上建立垂直生长习惯的力量和结构的正直在第二等的木部以内表明第二等的墙纤维素的基本角色。 | Chandrashekhar R Joshi Shivegowda Thammannagowda Takeshi Fujino Ji-Qing Gou Utku Avci Candace H. Haigler Lisa M. McDonnell Shawn D. Mansfield Bemnet Mengesha Nicholas C. Carpita Darby Harris Seth DeBolt Gary F. Peter | 2011 | Molecular Plant2011，4，2： | 4 |
| 3 | Response of blood pressure after percutaneous transluminal renal artery angioplasty and stenting显示文摘AIM: To evaluate the short and intermediate term out-come of percutaneous transluminal renal artery angioplasty (PTRA) and stenting particularly on blood pressure (BP) control and renal function and to evaluate predictors of poor BP response after successful PTRA and stenting. METHODS: We conducted a prospective analysis of all patients who underwent PTRA and stenting in our institute between August 2010 to September 2012. A total number of 86 patients were underwent PTRA and renal stenting. Selective angiography was done to confirm at least 70% angiographic stenosis. The predilatation done except few cases with critical stenosis, direct stenting was done in the rest of cases. All patients received aspirin 325 mg orally, and clopidogrel 300 mg orally within 24 h before the procedure. Heparin was used as the procedural anticoagulant agent. Optimal results with TIMI-Ⅲ flow obtained in all cases. Following stent placement, aspirin 150 mg orally once daily was continued for a minimum of 12 mo and clopidogrel 75 mg orally once daily for at least 4 wk. The clinical, radiological, electrocardiography, echocardiography and treatment data of all patients were recorded. The BP measurement, serum creatinine and glomerular filtration rate (GFR) were recorded before the procedure and 1 and 6 mo after PTRA. RESULTS: A total of 86 patients were included in the study. The mean age of study population was 55.87±11.85 years old and 67 (77.9%) of patients were male. There was a significant reduction in both systolic and diastolic BP at 1 mo after the procedure: 170.15±20.10 mmHg vs 146.60±17.32 mmHg and 98.38±10.55 mmHg vs 89.88±9.22 mmHg respectively (P=0.0000). The reduction in BP was constant throughout the follow-up period and was evident 6 mo after the procedure: 144.23±18.19 and 88.26±9.79 mmHg respectively (P=0.0000). However, no improvement in renal function was observed at any time during the follow-up period. After multivariate analysis, we found male sex, low GFR (<60 mL/min) and higher baseline mean BP as a poor predictors of successful outcome on BP response after PTRA and stenting. CONCLUSION: The PTRA and stenting can be considered as an effective therapeutic intervention for improving BP control with minimal effect on renal function. The male sex, higher baseline BP and low GFR are associated with poor BP response after successful PTRA and stenting. | Jayesh S Prajapati Sharad R Jain Hasit Joshi Shaurin Shah Kamal Sharma Sibasis Sahoo Kapil Virparia Ashok Thakkar | 2013 | World Journal of Cardiology2013，5，7： | 3 |
| 4 | An Overview of the JPEG 2000 Still Image Compression Standard 显示文摘 | M Rabbani R Joshi | 2000 | Signal Processing: Image Communication2000，17，1： | 2 |
| 5 | Change in pore size distribution due to consolidation of clays显示文摘 | Griffiths F J Joshi R C | 1989 | Gèotechnique1989，39，1： | 2 |
| 6 | Free radical scavenging behavior of folic acid: evidence for possible antioxidant activity 显示文摘 | Joshi R Adhikari S Patro BS | 2001 | Free Radic Biol Med2001，30，： | 1 |
| 7 | Nicotine inhibits apoptosis induced by chemotherapeutic drugs by up-regulating XIAP and survivin显示文摘 | Dasgupta P Kinkade R Joshi B | 2006 | Proc Natl Acad Sci USA2006，103，16： | 1 |
| 8 | Formation of hydroxyl radicals, hydrogen peroxide and aqueous electrons by pulse streamer corona discharge in aqueous solution显示文摘 | A A Joshi B R Locke | 1995 | J Hazardous materials1995，41，1： | 1 |
| 9 | International Journal of Powder Metallurgy显示文摘 | Joshi P B Krishnan P S Patel R H | 1998 | 34(4):63-741998，34，4： | 1 |
| 10 | Characteristics of indium tin oxide films deposited by R F magnetron sputiering显示文摘 | JOSHI R N | 1995 | Thin Solid Films1995，257，： | 1 |
| 11 | Characterization of mammalian elF4E family members显示文摘 | Joshi B Cameron A Jagus R | 2004 | Eur J Biochem2004，271，11： | 1 |
| 12 | Switching characterization of cascaded multilevel-inverter-controlled systems显示文摘 | Gupta R Ghosh A Joshi A | 2008 | IEEE Transactions on Industrial Electronics2008，55，3： | 1 |
| 13 | Image retrieval:ideas,influences,and trends of the new age显示文摘 | Datta R Joshi D Li J | 2008 | ACM ComputingSurveys2008，40，2： | 1 |
| 14 | UHF wind profiler observations of monsoon low level jet over Pune显示文摘 | JOSHI R R NARENDRA S DESHPANDE S M | 2006 | Indian Journal of Radio & Space physics2006，35，： | 1 |
| 15 | Identification of interleukin-13 receptor alpha2 chain overexpression in situ in high-grade diffusely infiltrative pediatric brainstem glioma显示文摘 | Joshi B H Puri R A Leland P | | 0，，03： | 1 |
| 16 | 查看详情显示文摘 | Toberer E S Joshi A Seshadri R | | 0，，： | 1 |
| 17 | A descriptive study of persistent oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer显示文摘 | Vatandoust S Joshi R Pittman K B | 2014 | Support Care Cancer2014，22，2： | 1 |
| 18 | Prophylactic efficacy of amifostine and its analogues against sulphur mustard toxicity 显示文摘 | Vijayaraghavan R Kumar P Joshi U | 2001 | Toxicology2001，163，23： | 1 |
| 19 | Flow properties of biodiesel fuel blends at low temperatures 显示文摘 | Joshi R M Pegg M J | 2007 | Fuel2007，86，12： | 1 |
| 20 | A systematic review of randomized trials evaluating regional techniques for postthoracotomy analgesia显示文摘 | Joshi GP Bonnet F Shah R | 2008 | Anesth Analg2008，107，3： | 1 |
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