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2535篇 您的检索式:作者名="Jones J P"
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1Assessment of the uncertainties in temperature change in China during the last century显示文摘We have used the China Homogenized Historic Temperature dataset and some long-term station series of the neighbor countries from CRUTEM3,a 5°×5° gridded dataset of monthly mean temperature since 1900,to provide a 107-year record of surface temperature trends and variability.We derived a comprehensive set of uncertainty estimates to accompany the data:measurement and sampling errors,uncertainties in temperature bias estimates,and uncertainties arising from limited observational coverage on large-scale averages have all been estimated.We reanalysed the temperature changes during the period of record.The best estimates of trends for 1900-2006 with uncertainties at 95% confidence range are about 0.09±0.017°C/decade for the year as a whole,and 0.14±0.021°C/decade,0.11±0.021°C/decade,0.04±0.017°C/decade,and 0.07±0.017°C/decade for winter,spring,summer and autumn respectively.For 1954-2006,the trends for annual,winter,spring,summer and autumn are:0.26±0.032°C/decade,0.35±0.046°C/decade,0.25±0.051°C/decade,0.16±0.037°C/decade and 0.22±0.055°C/decade.Winter saw the most significant warming trend in both 1900-2006 and 1954-2006,while during the most recent period(the satellite era,1979-2006),all the seasons show similar warming trends:0.45±0.13°C/decade,0.51±0.11°C/decade,0.52±0.16°C/decade,0.37±0.10°C/decade and 0.50±0.16°C/decade for annual,winter,spring,summer and autumn.Trends arising from urbanization have been evaluated as less than 5% of the total warming trend for 1951-2001,so this bias was not removed.LI QingXiang DONG WenJie LI Wei GAO XiaoRong JONES P KENNEDY J PARKER D 2010Chinese Science Bulletin2010,55,19:26
2Intentional ingestions of foreign objects among prisoners: A review显示文摘The intentional ingestion of foreign objects(IIFO) is described more commonly in prison populations than in the general population, with an estimated annual incidence of 1 in 1900 inmates in our state correctional facilities. Incidents often involve ingestion of small metal objects(e.g., paperclips, razor blades) or other commonly available items like pens or eating utensils. Despite ingestion of relatively sharp objects, most episodes can be clinically managed with either observation or endoscopy. Surgery should be reserved for those with signs or symptoms of gastrointestinal perforation or obstruction. For those with a history of IIFO, efforts should focus on prevention of recurrenceas subsequent episodes are associated with higher morbidity, significant healthcare and security costs. The pattern of IIFO is often repetitive, with escalation both in frequency of ingestions and in number of items ingested. Little is known about successful prevention strategies, but efforts to monitor patients and provide psychiatric care are potential best-practice strategies. This article aims to provide state-of-the art review on the topic, followed by a set of basic recommendations.David C Evans Thomas R Wojda Christian D Jones Andrew J Otey Stanislaw P Stawicki 2015World Journal of Gastrointestinal Endoscopy2015,7,3:10
3Die Montreal-Definition und -Klassifikation der gastro?sophagealen Refluxkrankheit: Ein globales evidenzbasiertes Konsensus-Papier显示文摘N Vakil S van Zanten P Kahrilas J Dent R Jones 2007Z Gastroenterol2007,,11:3
4Macrophage secretory products induce an inflammatory phenotype in hepatocytes显示文摘AIM:To investigate the influence of macrophages on hepatocyte phenotype and function.METHODS:Macrophages were differentiated from THP-1 monocytes via phorbol myristate acetate stimulation and the effects of monocyte or macrophageconditioned medium on HepG2 mRNA and protein expression determined.The in vivo relevance of these findings was confirmed using liver biopsies from 147 patients with hepatitis C virus(HCV)infection.RESULTS:Conditioned media from macrophages,but not monocytes,induced a transient morphological change in hepatocytes associated with upregulation of vimentin(7.8±2.5-fold,P=0.045)and transforming growth factor(TGF)-β1(2.6±0.2-fold,P<0.001)and downregulation of epithelial cadherin(1.7±0.02-fold,P=0.017)mRNA expression.Microarray analysis revealed significant upregulation of lipocalin-2(17-fold,P <0.001)and pathways associated with inflammation,and substantial downregulation of pathways related to hepatocyte function.In patients with chronic HCV,realtime polymerase chain reaction and immunohistochemistry confirmed an increase in lipocalin-2 mRNA(F0 1.0 ±0.3,F1 2.2±0.2,F2 3.0±9.3,F3/4 4.0±0.8,P= 0.003)and protein expression(F1 1.0±0.5,F2 1.3± 0.4,F3/4 3.6±0.4,P=0.014)with increasing liver injury.High performance liquid chromatography-tandem mass spectrometry analysis identified elevated levels of matrix metalloproteinase(MMP)-9 in macrophageconditioned medium,and a chemical inhibitor of MMP-9 attenuated the change in morphology and mRNA expression of TGF-β1(2.9±0.2 vs 1.04±0.1,P<0.001) in macrophage-conditioned media treated HepG2 cells.In patients with chronic HCV infection,hepatic mRNA expression of CD163(F0 1.0±0.2,F1/2 2.8±0.3,F3/4 5.3±1.0,P=0.001)and MMP-9(F0 1.0±0.4,F1/2 2.8±0.3,F3/4 4.1±0.8,P=0.011)was significantly associated with increasing stage of fibrosis.CONCLUSION:Secreted macrophage products alter the phenotype and function of hepatocytes,with increased expression of inflammatory mediators,suggesting that hepatocytes actively participate in liver injury.Michelle Melino Victoria L Gadd Gene V Walker Richard Skoien Helen D Barrie Dinesh Jothimani Leigh Horsfall Alun Jones Matthew J Sweet Gethin P Thomas Andrew D Clouston Julie R Jonsson Elizabeth E Powell 2012World Journal of Gastroenterology2012,18,15:3
5使用二甲双胍的禁忌证 证据显示应该修改二甲双胍的禁忌证显示文摘在英国前瞻性糖尿病研究(UNPOS)中,2型糖尿病患者被随机分入二甲双胍、磺酰脲类或胰岛素强化治疗组,3组患者取得了相似的血糖控制效果,微血管并发症终点事件显著降低。该项研究显示,肥胖患者使用二甲双胍治疗可以降低心血管事件的发生,二甲双胍治疗组的患者没有低血糖事件。G C Jones J P Macklin W D Alexander 李玉秀 2003英国医学杂志中文版2003,6,3:2
6Minireview dietary phytosterols:a review of metabolism,benefits and side effects显示文摘Ling W H Jones P J 1995Life Science1995,57,:2
7GI symptoms in diabetes mellitus are associated with both poor glycemic control and diabetic complications显示文摘Peter Bytzer Nicholas J Talley Johann Hammer Lisa J Young Michael P Jones Michael Horowitz 2002The American Journal of Gastroenterology2002,,3:2
8欧洲鼻腔鼻窦解剖术语意见书(二)显示文摘2014年,Rhinology刊登了European Position Paper on the Anatomical Terminology of the Internal Nose and Paranasal Sinuses,对于认识鼻科解剖名词具有重要的普及意义。考虑到国内耳鼻喉科医师获取和阅读英文文献的能力有限,但是又急需及时掌握学科领域内解剖名词的表述,我们通过与Rhinology编辑部及作者联系征得同意,翻译而成《欧洲鼻腔鼻窦解剖术语规范意见书》(以下简称《意见书》)。《意见书》中的所有解剖名词同时参考国内《英汉汉英医学分科词典(耳鼻咽喉科学分册)》进行统一,对于《英汉汉英医学分科词典(耳鼻咽喉科学分册)》中没有提及的名词给出了相应的补充。希望《意见书》对国内耳鼻喉科医师掌握并规范应用鼻科名词提供参考。《中国眼耳鼻喉科杂志》从第17卷第2期开始以连载形式刊登《意见书》。王德辉 王德云 于华鹏 孙希才 李晗 刘琢扶 刘全 张焕康 Lund VJ Stammberger H Fokkens WJ Beale T Bernal-Sprekelsen M Eloy P Georgalas C Gerstenberger C Hellings PW Herman P Hosemann WG Jankowski R Jones N Jorissen M Leunig A Onerci M Rimmer J Rombaux P Simmen D Tomazic PV Tschabitscher M Welge-Luessen A 2017中国眼耳鼻喉科杂志2017,17,3:2
9Extracellular matrix and integrin signalling:the shape of things to come显示文摘Boudreau N J Jones P L 1999Biochem J1999,339,3:2
10Dietary sitostanol reduces plaque formation but not lecithin cholesterol acyl transferase activity in rabbits 显示文摘NAANIOS F Y JONES P J H FROHLICH J J 1998Atheroscleresis1998,138,:1
11Assessing your company's knowledge management style 显示文摘Jordan J Jones P 1997Long Range Planning1997,30,3:1
12Minireview dietary phytosterols:a review metabolism,benefits and side effects 显示文摘Ling W H Jones P J H 1995Life Science1995,51,3:1
13Nutrient foraging traits in 10 co-occurring plant species of contrasting life forms显示文摘Einsmann J C Jones R H Mou P 1999The Journal of Ecology1999,87,:1
14Novel e-functionally substituted amino aeids: diphenylphosphinoglycines 显示文摘Heinicke J Peulecke N Jones P G 2005Chem Commum2005,,:1
15Expression and stability of amplified genes encoding 5-enolpyruvylshikimate-3-phosphate synthase in glyphosate-tolerant tobacco cells显示文摘WANG Y JONES J WELLER S GOLDSBROUGH P 1991Plant Molecular Biology1991,17,6:1
16Conjugated linoleic acid and obesity control: efficacy and mechanisms 显示文摘Wang Y W Jones P J 2004Int J Obes Relat Metab Disord2004,28,:1
17Evaluation of Sediment Contamination by Polycyclic Aromatic Hydrocarbons in the Gironde Estuary显示文摘Budzinski H Jones I Belocq J P 1997Mar Chem1997,58,12:1
18Correlation between microstructure and micro-hardness in a friction stir welded 2024 aluminium alloy显示文摘Jones M J Heurtier P Desrayaud C 2005Seripta Mater2005,52,8:1
19Toxoplasma gondii infection in humans and ani- mals in the United States 显示文摘Dubey J P Jones J L 2008Int J Parasitol2008,38,11:1
20Chemically induced phosphorescence from manganese (II) during the oxidation of various compounds by manganese (III), (IV) and (VII) in acidic aqueous solutions 显示文摘Barnett N W Hindson B J Jones P 2002Analytica Chimica Acta2002,451,2:1
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