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| 1 | Improved scoring system for the electrocardiographic diagnosis of left ventricular hypertrophy显示文摘BACKGROUND Left ventricular hypertrophy(LVH) is a common manifestation of cardiovascular disease and a risk factor for cardiovascular morbidity and mortality, but available methods for its electrocardiographic(ECG) diagnosis have limited accuracy.AIM To investigate findings associated with LVH on ECG and developed an improved system for the diagnosis of LVH.METHODS A cohort study comparing ECG data acquired within 30 days of transthoracic echocardiography(TTE) was performed. Multivariate regression analysis identified ECG findings associated with increased LV mass and mass index. A scoring system was derived and performance compared to established criteria for LVH.RESULTS Data from 5486 outpatients with TTEs and corresponding ECGs were included in the derivation cohort, 333(6.1%) of whom had LVH by TTE. In the primary regression analysis, findings associated with LVH were amplitudes of Q in V3, R in V6, S in V3, T in V6, P' in V1, P in V6, as well as R and T-axis discordance, R peak time in V6, QRS duration, weight, height, sex, and age. From this we derived a score consisting of 5 criteria, and validated it in an independent cohort of 910 patients. With a threshold of 1.5 points, sensitivity and specificity were67.9% and 81.4%, and 62.5% and 83.2% in the derivation and validation cohorts,respectively. With a threshold of 2 points, sensitivity and specificity were 42.3% and 93.0%, and 37.5% and 93.4% in these cohorts.CONCLUSIONS This score had superior sensitivity for detection of LVH by ECG while making a modest sacrifice in specificity compared to conventional criteria. | Eric D Braunstein Lori B Croft Jonathan L Halperin Steve L Liao | 2019 | World Journal of Cardiology2019，11，3： | 2 |
| 2 | Enzymatic hydrolysis of lime-pretreated corn stover and investigation of the HCH-1 model: inhibition pattern, degree of inhibition,validity of simplified HCH-1 model 显示文摘 | Jonathan P Zhu L Cesar B G | 2007 | Bioresource Technology2007，98，16： | 1 |
| 3 | Integrated optical dull Mach-Zehnder interferometer sensor显示文摘 | Hua P Jonathan L B Quigley G Q | 2002 | Sensors and Actuators B2002，87，2： | 1 |
| 4 | Changes in pore size distribution upon thermal cycling of TATB-based explosives measured by ultra-small angle X-Ray scattering显示文摘 | Trevor M W Tony van B Jonathan R I L | 2006 | Propellants Explosives Pyrotechnics2006，31，6： | 1 |
| 5 | HIV-1 Integrase Interaction with U3 and U5 Terminal Sequences in vitro Defined Using Substrates with Random Sequences显示文摘 | Elena B Jonathan L | 2002 | JBC2002，277，18： | 1 |
| 6 | A plant DNA minipreparation: version II 显示文摘 | Stephen L D Jonathan W James B H | 1983 | Plant Molecular Biology Reporter1983，1，4： | 1 |
| 7 | Probing electronic communication in covalently linked multiporphyrin arrays: A guide to the ra tional design of molecular photonic devices显示文摘 | Dewey H David F B Jonathan S L | 2002 | Aec Chem Res2002，35，1： | 1 |
| 8 | A Within Firm Analysis of Current and Expected Future Audit Lag Determinants显示文摘 | Behn K B Searcy D L Jonathan B W | 2006 | Joural of Information Systems2006，20，1： | 1 |
| 9 | C-reactive protein concentra-tion and the vascular benefits of statin therapy:an analysis of 20,536 patients in the Heart Protection Study显示文摘 | Jonathan E Derrick B Emma L | 2011 | LANCET2011，，9764： | 1 |
| 10 | Aggregation and deposi- tion characteristics of fullerene nanoparticles in aqueous sys- tems显示文摘 | Jonathan B Hrl~ne L Wiesner M | 2005 | Journal of Nanoparticle Research2005，，7： | 1 |
| 11 | Understorey plant community structure in lower montane and subalpine forests, Grand Canyon National Park, USA 显示文摘 | Daniel C L Jonathan D B Peer Z F | 2005 | Journal of Biogeography2005，32，12： | 1 |
| 12 | Volatility in the Gold Futures Market 显示文摘 | Jonathan B Brian L | 2007 | nternational Integration Studies2007，，2： | 1 |
| 13 | Pulmonary fat embolism in the early postoperative period显示文摘 | Timothy A Betty L Jonathan B | 1998 | Anestheaiology1998，89，： | 1 |
| 14 | Fast Quantum Gates for Cold Trapped Ions显示文摘 | JONATHAN D PLENIO M B KNIGHT P L | 2000 | Phys Rev A2000，62，04： | 1 |
| 15 | Study of Plant-Air Transfer of PCBs from an Evergreen Shrub: Implications for Mechanisms and Modeling 显示文摘 | Jonathan L B Gareth O T Gerha D | 2003 | Environ Sci Technol2003，37，： | 1 |
| 16 | Uptake and storage of PCBs by plant cuticles 显示文摘 | Claudia M Gareth O T Jonathan L B | 2008 | Environ Sci Technol2008，42，： | 1 |
| 17 | Changes in pore size distribution upon thermal cycling of TATB-based explosives measured by ultra-small angle X-ray scattering显示文摘 | Trevor M W van Tony B Jonathan R I L | 2006 | Propellants Explosives Pyrotechnics2006，31，6： | 1 |
| 18 | Induction of Th17Cells in the Tumor Microenvironment Improves Survival in a Murine Model of Pancreatic Cancer显示文摘 | Jennifer L Gnerlich Jonathan B Mitchem Joshua S Weir | 2010 | Immunology2010，185，7： | 1 |
| 19 | Ferroelectric and antiferroelectric films for microeletromechanical systems applications显示文摘 | BAOMIN X U ERIC C L JONATHAN J B | 2000 | Thin Solid Films2000，，： | 1 |
| 20 | De Lphinidin,a dietary anthocyanidin,inhibits vascu Lar endothe Lia L growth factor receptor-2 phosphory Ltion显示文摘 | Sy Lvie L Me Lanie B Jonathan M | 2006 | Carcinogenesis2006，27，5： | 1 |
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