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| 1 | Collinear holographic data storage technologies显示文摘In the era of information explosion,the demand of data storage is increased dramatically.Holographic data storage technology is one of the most promising next-generation data storage technologies due to its high storage density,fast data transfer rate,long data life time and less energy consumption.Collinear holographic data storage technology is the typical solution of the holographic data storage technology which owns a more compact,compatible and practical system.This paper gives a brief review of holographic data storage,introduces collinear holographic data storage technology and discusses phase modulation technology being used in the holographic data storage system to achieve higher storage density and higher data transfer rate. | Xiao Lin Jinpeng Liu Jianying Hao Kun Wang Yuanying Zhang Hui Li Hideyoshi Horimai Xiaodi Tan | 2020 | Opto-Electronic Advances2020，3，3： | 8 |
| 2 | Effect of Yiqihuoxue prescription on myocardial energy metabolism after myocardial infarction via cross talk of liver kinase B1-depen-dent Notch1 and adenosine 5'-monophosphate-activated protein kinase显示文摘OBJECTIVE: To investigate the effect of Yiqihuoxue prescription(YQHX) from Traditional Chinese Medicine(TCM) on myocardial glucose and lipid metabolism after myocardial infarction via the cross talk between the liver kinase B1(LKB1)-dependent Notch1 and adenosine 5'-monophosphate(AMP)-activated protein kinase(AMPK). YQHX was prepared with substances with properties that benefit, to activate blood circulation based on the TCM theory.METHODS: Animal models of myocardial infarction were established by ligating Sprague Dawley rats' left anterior descending coronary arteries. The animals were randomly divided into a myocardial infarction(MI) group, a YQHX group, a perindopril group, a γ-secretase inhibitor, Notch signal inhibitor(DAPT) group, a DAPT+YQHX group and a sham group. The related drugs were administered on the second day after operation, and changes in the relevant indexes were examined on weeks 1 and 4.Changes in cardiac structure and function were examined by echocardiography. The glucose and free fatty acids(FFA) were examined by ELISA. The expression of Notch, LKB1 and AMPK m RNA was examined by a real-time fluorescence quantitative method. The expression of glucose transporter 4(GLUT4), and the expression of total acetyl-Co A carboxylase(ACC) and its phosphorylation were examined by western blotting.RESULTS: Compared with the sham group, the expression of Notch, LKB1 and AMPK m RNA in the MI group was lower. Compared with the MI group, the expression of these m RNAs in the YQHX and perindopril groups was higher, and their expression in the DAPT group was lower. At all time points, the protein expression of GLUT4 and p ACC decreased in the MI group. On week 1, the expression of p ACC protein was higher. In the DAPT group, the expression of p ACC protein decreased. Compared with the YQHX group, the expression of p ACC protein in the DAPT + YQHX group was lower. On week 4,compared with the MI group, the expression of GLUT4 protein in the YQHX group and the perindo-pril group was higher. The expression of GLUT4 protein in the DAPT group decreased. Compared with the YQHX group, the expression of GLUT4 protein in the DAPT+YQHX group was lower. There was no significant difference in the expression of ACC protein between the groups.CONCLUSION: YQHX promoted cross talk between the LKB1-dependent Notch1 and AMPK in myocardial tissue after myocardial infarction. Furthermore,it regulated the glucose and lipid metabolism of cardiomyocytes at different time points, thereby ameliorating the cardiac energy metabolism via different mechanisms and protecting the heart. | Wu Jiangong Chen Xi Guo Shuwen Liu Wenchen Zhang Lu Li Fanghe Wu Jiani Huang Xiaolou Cai Qian Tan Xiaobo Wang Hui | 2017 | Journal of Traditional Chinese Medicine2017，37，3： | 7 |
| 3 | Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos显示文摘 | Yuyu Niu Bin Shen Yiqiang Cui Yongchang Chen Jianying Wang Lei Wang Yu Kang Xiaoyang Zhao Wei Si Wei Li Andy Peng Xiang Jiankui Zhou Xuejiang Guo Ye Bi Chenyang Si Bian Hu Guoying Dong Hong Wang Zuomin Zhou Tianqing Li Tao Tan Xiuqiong Pu Fang Wang Shaohu | 2014 | Cell2014，，： | 3 |
| 4 | Trifolirhizin induces autophagy-dependent apoptosis in colon cancer via AMPK/mTOR signaling显示文摘Dear Editor,Colorectal cancer(CRC)is one of the most frequent diseases with high mortality around the world.Conventional treatments of CRC remain unsatisfactory due to the increasing recurrence rate and adverse reactions including neutropenia,drug resistance,etc.Recently,autophagy has been shown to be involved in regulating cancer development and progression by regulating apoptosis through pro-apoptosis proteins including caspases,in addition to being a potential target for cancer therapeutic intervention.1 Trifolirhizin(Supplementary Fig.S1a)is a natural flavonoid glycosides isolated from Sophora flavescens as well as a bioactive constituent of Xian-Lian-Ke-Li,a commercial traditional Chinese medicine for the cancer prevention.Numerous evidence manifested that trifolirhizin inhibited proliferative activity in melanoma B16 cell,lung cancer H23 cell,human ovarian A2780 cell,and human gastric cancer cell MKN45.2 However,its pharmacological effect and mechanism on CRC remain elusive.Herein,we evaluated the effect of trifolirhizin on autophagy and apoptosis on CRC as well as its related mechanisms,in order to provide evidence to develop a potential agent with less adverse effect in treating CRC. | Dongdong Sun Weiwei Tao Feng Zhang Weixing Shen Jiani Tan Liu Li Qinghai Meng Yugen Chen Ye Yang Haibo Cheng | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 3 |
| 5 | Overexpression of the IGF2 -mRNA binding protein p62 in transgenic mice induces a steatotic phenotype显示文摘 | Elisabeth Tybl Fu-Dong Shi Sonja M. Kessler Sascha Tierling J?rn Walter Rainer M. Bohle Stefan Wieland Jianying Zhang Eng M. Tan Alexandra K. Kiemer | 2010 | Journal of Hepatology2010，，5： | 1 |
| 6 | Lensless complex amplitude demodulation based on deep learning in holographic data storage显示文摘To increase the storage capacity in holographic data storage(HDS),the information to be stored is encoded into a complex amplitude.Fast and accurate retrieval of amplitude and phase from the reconstructed beam is necessary during data readout in HDS.In this study,we proposed a complex amplitude demodulation method based on deep learning from a single-shot diffraction intensity image and verified it by a non-interferometric lensless experiment demodulating four-level amplitude and four-level phase.By analyzing the correlation between the diffraction intensity features and the amplitude and phase encoding data pages,the inverse problem was decomposed into two backward operators denoted by two convolutional neural networks(CNNs)to demodulate amplitude and phase respectively.The experimental system is simple,stable,and robust,and it only needs a single diffraction image to realize the direct demodulation of both amplitude and phase.To our investigation,this is the first time in HDS that multilevel complex amplitude demodulation is achieved experimentally from one diffraction intensity image without iterations. | Jianying Hao Xiao Lin Yongkun Lin Mingyong Chen Ruixian Chen Guohai Situ Hideyoshi Horimai Xiaodi Tan | 2023 | Opto-Electronic Advances2023，6，3： | 1 |
| 7 | Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos显示文摘 | Yuyu Niu Bin Shen Yiqiang Cui Yongchang Chen Jianying Wang Lei Wang Yu Kang Xiaoyang Zhao Wei Si Wei Li Andy Peng Xiang Jiankui Zhou Xuejiang Guo Ye Bi Chenyang Si Bian Hu Guoying Dong Hong Wang Zuomin Zhou Tianqing Li Tao Tan Xiuqiong Pu Fang Wang Shaohu | 2014 | Cell2014，，： | 1 |
| 8 | Phase I study of icotinib hydrochloride (BPI-2009H), an oral EGFR tyrosine kinase inhibitor, in patients with advanced NSCLC and other solid tumors显示文摘 | Qiong Zhao Jianzhong Shentu Nong Xu Jianya Zhou Guangdie Yang Yinan Yao Fenlai Tan Dongyang Liu Yingxiang Wang Jianying Zhou | 2010 | Lung Cancer2010，，2： | 1 |
| 9 | Oxidative phosphorylation safeguards pluripotency via UDP-N-acetylglucosamine显示文摘Dear Editor,Embryonic stem cells(ESCs)have been assumed to possess immature mitochondria and to favor anaerobic glycolysis over oxidative phosphorylation(OXPHOS)for energy production.This proposition is largely based on the findings that ESCs possess globular mitochondria with blurred cristae,and the facts that ESCs have higher glycolysis activity and lower mitochondrial respiration capacity than somatic cells(Kondoh et al.,2007;Folmes et al.,2011,2012;Zhang et al.,2012;Xu et al.,2013;Ito and Suda,2014;Gu et al.,2016).However,recent studies have shown that mitochondrial autophagy and mitochondrial dynamics are pivotal for ESC self-renewal and pluripotency(Todd et al.,2010;Liu et al.,2016,2020;Wang et al.,2019;Zhong et al.,2019).These studies have raised a fundamental question:what is the contribution and functional mechanism of mitochondrial respiration in pluripotency regulation? | Jiani Cao Meng Li Kun Liu Xingxing Shi Ning Sui Yuchen Yao Xiaojing Wang Shiyu Li Yuchang Tian Shaojing Tan Qian Zhao Liang Wang Xiahua Chai Lin Zhang Chong Liu Xing Li Zhijie Chang Dong Li Tongbiao Zhao | 2023 | Protein & Cell2023，14，5： | 1 |
| 10 | Understanding the change of land space utilization efficiency with different functions and its coupling coordination: A case study of Urban Agglomeration in the Middle Reaches of the Yangtze River, China显示文摘Land spaces function in capacities of urban development,agricultural production,and ecological conservation,among many others.Research of land space utilization efficiency(LSUE)and coupling coordination relationships among its subsystems are significant for sustainable land space development.In this study,taking the Urban Agglomeration in the Middle Reaches of the Yangtze River(UAMRYR)as the study area,we establish a measurement index system to evaluate the LSUE(2000–2018)and analyze its coupling coordination degree by utilizing an improved coupling coordination model.The main results include the following.(1)The average efficiency levels of urban space and agricultural space in the UAMRYR increased 2000–2018,while the average efficiency of ecological space declined.(2)The spatial pattern of the LSUE values varied greatly,with the distributions of high-efficiency and low-efficiency levels significantly different.(3)The coupling degree of LSUE includes three types,i.e.,high-level coupling,break-in,and antagonism.Each coupling degree type was characterized by change over time.(4)The proportion of areas with high coupling coordination and moderate coupling coordination increased from 2000 to 2018,while the proportion of areas with basic coupling coordination,moderate imbalance,and serious imbalance declined during this period.Given that the spatial differentiation of the LSUE and its coupling coordination,it is necessary to implement a differential land space development strategy in the UAMRYR.This study is helpful to promote the efficient utilization and coordinated development of land space utilization systems. | YANG Bin YANG Jun TAN Li XIAO Jianying | 2023 | Journal of Geographical Sciences2023，33，2： | 1 |
| 11 | Effect of Ultraviolet Aging on Asphalt Rheological Properties显示文摘This paper simulated the ultraviolet aging process of asphalt and used dynamic mechanic analysis(DMA)method to evaluate the effect of ultraviolet aging on the asphalt rheological properties.After having experienced ultraviolet aging,the low temperature performance of asphalt binder decreased significantly,with its complex modulus increased and phase angle decreased along with changing rheological properties as compared to the performance of original asphalt binder.The ultraviolet aging process would make asphalt binder more sensitive to brittle and fatigue failure.On the basis of the time-temperature superposition principle(TTSP),the viscoelastic transition frequency(ωT)is proposed to evaluate the effect of ultraviolet aging.It is found that with the increase in ultraviolet aging time,theωT moves to the lower frequency range gradually.Since the viscoelastic transition frequency is sensitive to the effect of aging,it can be used as an indicator of ultraviolet aging. | Wang Jiani Xue Zhongjun Tan Yiqiu Zhang Lei | 2013 | China Petroleum Processing & Petrochemical Technology2013，15，4： | 0 |
| 12 | Improved phase retrieval in holographic data storage based on a designed iterative embedded data显示文摘Embedded data are used to retrieve phases quicker with high accuracy in phase-modulated holographic data storage(HDS).We propose a method to design an embedded data distribution using iterations to enhance the intensity of the high-frequency signal in the Fourier spectrum.The proposed method increases the antinoise performance and signal-to-noise ratio(SNR)of the Fourier spectrum distribution,realizing a more efficient phase retrieval.Experiments indicate that the bit error rate(BER)of this method can be reduced by a factor of one after 10 iterations. | Changyu YU Suping WANG Ruixian CHEN Jianying HAO Qijing ZHENG Jinyu WANG Xianying QIU Kun WANG Dakui LIN Yi YANG Hui LI Xiao LIN Xiaodi TAN | 2021 | Frontiers of Optoelectronics2021，14，4： | 0 |
| 13 | A NEW METHOD OF MECHANISM SYNTHESIS FOR BIPED ROBOTS显示文摘ANEWMETHODOFMECHANISMSYNTHESISFORBIPEDROBOTS①TanGuanzhengInstituteofRobotics,CentralSouthUniversityofTechnology,Changsha41008... | Tan Guanzheng Institute of Robotics, Central South University of Technology, Changsha 410083 Zhu Jianying Department of Mechanical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 | 1997 | 中国有色金属学会会刊:英文版1997，7，1： | 0 |
| 14 | Mesoporous Silica (HMS) Based Composite Adsorbents and Its CO2 Adsorption Performance显示文摘 | Jie Liu Qian Tan Junsong Bai Jianying Liu Chenghua Xu Shengyu Liu Changwu Zou Wanglai Cen | 2016 | 功能材料信息2016，13，3： | 0 |
| 15 | Mechanical stimulation of the scalp improves the extra-and intracranial blood circulation in humans and mice显示文摘Background:Scalp combing,as an ancient method of health care,has been used for thousands of years in traditional Chinese medicine.Although this method is considered to be beneficial for the blood circulation of the head,the underlying mechanisms remain unclear.Methods:Both human participants and mice were used in this study.In participants,the scalp was stimulated by combing continuously for 5 min,and the temperature was measured using infrared thermal imaging before and after stimulation.In mice,the temperature was determined before and at 5,15,and 30 min after a 5-min scalp mechanical stimulation(SMS).Additionally,the vasculature of the mice was labeled with retro-orbital fluorescein isothiocyanate-dextran injection,and the capillaries were observed directly under a confocal microscope.Using in vivo CLARITY imaging and the spectrofluorometric detection of Evans Blue dye extravasation,the bloodebrain barrier permeability was assessed.Results:SMS increased the temperature of the left ear significantly in human(P=.0247)while can slightly increase the temperature of the right ear and the face without significant difference(P>.05).Moreover,SMS can significantly slow the decrease in the temperature of the external auditory canal at 5 min(P=.0153)and in body temperature at 15 min(P=.0295)after SMS whereas no significant difference in body temperature at 30 min(P>.05)compared with control mice.Furthermore,capillaries of the ear with a diameter of less than 8 mm were significantly dilated(P=.0006)following SMS and the number of dextran dots was higher at 15 min(P>.05)and 30 min(F=10.98,P=.037)after SMS intervention compared with control mice.Conclusion:Our study provides strong evidence to support the notion that scalp combing can improve extra-and intracranial blood circulation under healthy conditions. | Yan Tan Fang He Ce Zhang Jiani Zhang Ziwei Chen Xu Wang Peng Wei Yinan Nan Louis Lei Jin Qian Hua | 2020 | Journal of Traditional Chinese Medical Sciences2020，7，4： | 0 |
| 16 | Effect of VEGF/GREDVY Modified Surface on Vascular Cells Behavior显示文摘We synthesized B-He/B-GREDVY and immobilized them on avidin-coated surfaces.To examine the immobilization of molecules in the material, the following experiments were performed:fluorescein isothiocyanate(FITC) fluorescence staining, water contact angle and atomic force microscopy(AFM) measurements. Besides, the biological evaluation experiments were also performed, such as platelets adhesion and activation, the culturing of smooth muscle cells(SMC) and endothelial cells(EC). These experimental results show that the modified surfaces could prevent the hyperproliferation of SMC, and promote the proliferation and migration of EC and EPC. Furthermore, the adding of VEGF improved the EC adhesion in a dynamic environment. Generally, it is expected that the modified surfaces could be used to accelerate the formation of the newly endothelial layer for the construction of platforms for coronary artery stent therapy. | 魏来 TAN Jianying LI Li WANG Huanran LIU Sainan ZENG Zheng LIU Tao WANG Jian 陈俊英 WENG Yajun | 2024 | Journal of Wuhan University of Technology(Materials Science)2024，39，1： | 0 |
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