|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | On adjacent-vertex-distinguishing total coloring of graphs显示文摘In this paper, we present a new concept of the adjacent-vertex-distinguishing total coloring of graphs (briefly, AVDTC of graphs) and, meanwhile, have obtained the adjacent-vertex-distinguishing total chromatic number of some graphs such as cycle, complete graph, complete bipartite graph, fan, wheel and tree. | ZHANG Zhongfu, CHEN Xiang’en, LI Jingwen, YAO Bing, LU Xinzhong & WANG Jianfang College of Mathematics and Information Science, Northwest Normal University, Lanzhou 730070, China Department of Computer, Lanzhou Normal College, Lanzhou 730070, China Institute of Applied Mathematics, Lanzhou Jiaotong University, Lanzhou 730070, China College of Information and Electrical Engineering, Lanzhou Jiaotong University, Lanzhou 730070, China Institute of Applied Mathematics, Chinese Academy of Sciences, Beijing 100080, China | 2005 | Science China Mathematics2005，48，3： | 173 |
| 2 | Genetic basis and breeding application of clonal diversity and dual reproduction modes in polyploid Carassius auratus gibelio显示文摘A unisexual species is generally associated with polyploidy, and reproduced by a unisexual reproduction mode, such as gyno- genesis, hybridogenesis or parthenogenesis. Compared with other unisexual and polyploid species, gibel carp (Carassius au- ratus gibelio) has a higher ploidy level of hexaploid. It has undergone several successive rounds of genome polyploidy, and experienced an additional, more recent genome duplication event. More significantly, the dual reproduction modes, including gynogenesis and sexual reproduction, have been demonstrated to coexist in the polyploid gibel carp. This article reviews the genetic basis concerning polyploidy origin, clonal diversity and dual reproduction modes, and outlines the progress in new va- riety breeding and gene identification involved in the reproduction and early development. The data suggests that gibel carp are under an evolutionary trajectory of diploidization. As a novel evolutionary developmental (Evo-Devo) biology model, this work highlights future perspectives about the functional divergence of duplicated genes and the sexual origin of vertebrate animals. | GUI JianFang* & ZHOU Li State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China | 2010 | Science China(Life Sciences)2010，53，4： | 62 |
| 3 | Detection of Grass Carp Hemorrhage Virus (GCHV) from Vietnam and Comparison with GCHV Strain from China显示文摘Grass carp plays an important role in small-scale aquaculture in Vietnam. However, a severe disease, known in Vietnam as 'Red Spot Disease', is causing significant economic loss in grass carp aquaculture. In this study, the tissue samples isolated from the grass carp with Red Spot Disease in Vietnam are investigated and comparied with the control GCHV isolated in China by experimental infection, culture cell infection, serological cross reactivity, and RT-PCR amplification. Infected grass carp exhibits hemorrhage symptoms about 5 days after experimental injection with GCHV-V (Vietnam) strain. The symptoms and lethality induced by the GCHV-V strain are identical to that induced by the Chinese GCHV-9014 strain. The Chinese GCHV-873 strain induces typical cytopathogenic effects in 4 cell lines, such as CIK, CAB, FHM and GCO, from the 6 fish cell lines examined. No cytopathogenic effects are observed in all the 6 examined cell lines, including CAB, FHM, CIK, EPC, CCO and GCO, infected by the GCHV-V strain and GCHV-9014 strain. Immunodiffusion assays demonstrate an obvious cross-reactivity among three GCHV strains. Precipitin lines are clearly observed not only between the anti-GCHV-873 serum and the two strains GCHV-873 and GCHV-9014, but also between the anti-GCHV-873 serum and the GCHV-V strain. GCHV can be detected by immunodiffusion assays after three generations of blind propagations in the cell lines inoculated by GCHV-V strain. This implicates that GCHV-V viruses have been replicated and amplified despite there being no cytopathogenic effects observed in these examined cell lines. Three genome segments of GCHV, including S8, S9 and S10, are amplified by three sets of PCR primers designed according to the segment sequences published recently. The Q8fp and Q8rp primer set specific for genome segment S8 amplifies a 955 bp fragment from the extracted sample of diseased fish with Red Spot Disease, and the fragment size is identical to that amplified by the same primer set from control GCHV-873 strain. Simultaneously, the Q9fp and Q9rp primer set specific for genome segment S9 generates a same 635 bp product, and the Q10fp and Q10rp primer set specific for genome segment S10 produces a same 697 bp fragment from both template samples of diseased fish with Red Spot Disease and control GCHV-873 strain. The RT-PCR amplification and corresponding size comparison data indicate that the three GCHV-V genome segments extracted from the diseased grass carp with Red Spot Disease in Vietnam should be identical to that in control GCHV-873 strain from China. The data confirm that the causative agent of grass carp Red Spot Disease in Vietnam is a virus, and the virus is closely similar to GCHV strain in China. | 张奇亚 Ruan Hongmei Li Zhenqiu Zhang Jing Gui Jianfang | 2003 | High Technology Letters2003，9，2： | 20 |
| 4 | Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor显示文摘According to the World Health Organization(WHO)newly updated situation report on March 18th,2020,the coronavirus disease 2019(COVID-19)pandemic has confirmed 191,127 cases and claimed 7807 deaths worldwide.1 The etiological agent of COVID-19 has been identified as a novel coronavirus,the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),belonging to Sarbecovirus subgenus(genus Betacoronavirus,family Coronaviridae)and showing 79.6 and 96.2%sequence identity in nucleotide to SARS-CoV and a bat coronavirus(BatCoV RaTG13),respectively.2–4 Like SARS-CoV infection,a substantial fraction of COVID-19 patients exhibits severe respiratory symptoms and has to be hospitalized in intensive care unit.5–8 Although the mortality rate of COVID-19 is significantly lower than that of SARS-CoV infection,SARS-CoV-2 shows much higher human-to-human transmission rate,rapidly leading to a global pandemic declared by WHO on March 11th,2020. | Xiangyu Chen Ren Li Zhiwei Pan Chunfang Qian Yang Yang Renrong You Jing Zhao Pinghuang Liu Leiqiong Gao Zhirong Li Qizhao Huang Lifan Xu Jianfang Tang Qin Tian Wei Yao Li Hu Xiaofeng Yan Xinyuan Zhou Yuzhang Wu Kai Deng Zheng Zhang Zhaohui Qian Yaokai Chen Lilin Ye | 2020 | Cellular & Molecular Immunology2020，17，6： | 17 |
| 5 | Parkinson’s disease in China:a forty-year growing track of bedside work显示文摘The number and health burden of Parkinson’s disease increase rapidly in China.It is estimated that China will have nearly half of the Parkinson’s disease population in the world in 2030.In this review,we present an overview of epidemiology and health economics status of Parkinson’s disease across China and discuss the risk factors of Parkinson’s disease and related complications.From the view of clinical research,we also discuss the current status of clinical trials,diagnostic biomarkers,treatment of Parkinson’s disease,tertiary network and post-occupation education in Chinese Parkinson’s disease clinics. | Gen Li Jianfang Ma Shishuang Cui Yixi He Qin Xiao Jun Liu Shengdi Chen | 2019 | Translational Neurodegeneration2019，8，1： | 16 |
| 6 | Natural and artificial polyploids in aquaculture显示文摘Genome polyploidy has been revealed to result in evolutionary advantages and novelties,and therefore,polyploid aquatic animals may possess excellent traits of economic interest including rapid growth,extensive adaptability and disease resistance.For this reason,numerous species of natural polyploid fishes,such as common carp,gibel carp,crucian carp,salmon,and sturgeon,were chosen as important target species for aquaculture.Many artificial polyploids have been commercially utilized for aquaculture and most of them were created from natural polyploid fishes of the Cyprinidae and Salmonidae.Thanks to the easy mass production and better economic traits in growth and flesh quality,the synthetized autopolyploids or allopolyploids from natural polyploid species in cyprinid fishes have been extensively applied to aquaculture throughout China.This review outlines polyploidy advantages and innovative opportunities,lists natural polyploid species used in aquaculture,and summarizes artificial polyploids that have been induced or synthetized,and used in aquaculture.Moreover,some main research trends on polyploid utilization and ploidy manipulation of aquaculture animals are also introduced and discussed in the review. | Li Zhou Jianfang Gui | 2017 | Aquaculture and Fisheries2017，2，3： | 16 |
| 7 | Roles of a sustained activation of NCED3 and the synergistic regulation of ABA biosynthesis and catabolism in ABA signal production in Arabidopsis显示文摘ABA, acting as a stress signal, plays crucial roles in plant resistance to water stress. Because ABA signal production is based on ABA biosynthesis, the regulation of NCED, a key enzyme in the ABA biosynthesis pathway, is normally thought of as the sole factor controlling ABA signal production. Here we demonstrate that ABA catabolism in combination with a synergistic regulation of ABA biosynthesis plays a crucial role in governing ABA signal production. Water stress induced a significant accumulation of ABA, which exhibited different patterns in detached and attached leaves. ABA catabolism followed a temporal trend of exponential decay for both basic and stress ABA, and there was little difference in the catabolic half-lives of basic ABA and stress ABA. Thus, the absolute rate of ABA catabolism, i.e. the amount of ABA catabolized per unit time, increases with increased ABA accumulation. From the dynamic processes of ABA biosynthesis and catabolism, it can be inferred that stress ABA accumulation may be governed by a synergistic regulation of all the steps in the ABA biosynthesis pathway. Moreover, to maintain an elevated level of stress ABA sustained activation of NCED3 should be required. This inference was supported by further findings that the genes encoding major enzymes in the ABA biosynthesis pathway, e.g. NCED3, AAO3 and ABA3 were all activated by water stress, and with ABA accumulation progressing, the expressions of NCED3, AAO3 and ABA3 remained activated. Data on ABA catabolism and gene expression jointly indicate that ABA signal production is controlled by a sustained activation of NCED3 and the synergistic regulation of ABA biosynthesis and catabolism. | REN HuiBo FAN YiJian GAO ZhiHui WEI KaiFa LI GuiFen LIU Jing CHEN Lin LI BingBing HU JianFang JIA WenSuo | 2007 | Chinese Science Bulletin2007，52，4： | 12 |
| 8 | Sedimentary records of eutrophication in the Changjiang Estuary upwelling area over last 100 a显示文摘The upwelling area in the Changjiang Estuary was selected to collect the core, where the red tide occurred frequently and hypoxic existed. The total organic carbon (TOC), total nitrogen (TN), biogenic silica (BSi) and stable organic carbon isotopic ratios(δ13 Corg) were determined on the 210Pb-dated sediment core. The concentrations of TOC, TN, BSi as well as their sedimentation fluxes have increased to some extent since the 1970s. TOC and TN fluxes increased about 45%, 36% respectively. The average δ13 Corg value in the core was -23.67×10-3 which remained nearly constant before the 20 century. The δ13 Corg values increased after the 1900s, two marked increases were observed from the 1950s and the 1970s. A simple δ13 Corg model was used to estimate the contribution of terrigenous and marine organic matter inputs for the sediment, which indicated the increase in accumulation since the 1970s has been almost exclusively marine. The increasing of marine organic matter accumulation (TOC, TN and BSi) was corresponding with the increasing of fertilizer consumption and the NO3-N budgets from the Changjiang River. The riverine runoff of fertilizers and nutrients stimulated the algae blooming. Enhanced primary production resulted in an enrichment of organic matter in the sediment. These data support the hypothesis that anthropogenic nutrient loading has been a significant factor on the eutrophication in the Changjiang Estuary. | FENG Xuwen JING Xianglong YU Xiaoguo LI Hongliang CHEN Jianfang QIAN Jiangchu | 2008 | Acta Oceanologica Sinica2008，27，6： | 12 |
| 9 | Discovery of a male-biased mutant family and identification of a male-specific SCAR marker in gynogenetic gibel carp Carassius auratus gibelio显示文摘Gibel 鲤鱼(Carassius auratus gibelio ) 是一特别地有在自然产地的男性的次要的比率的 gynogenetic 种类,而是它的男起源和性决心机制是未知的。在这研究,一个偏导男性的变异的家庭从 gynogenetic gibel 鲤鱼被发现,并且一个男性特定的疤标记从变异的家庭被识别。正常精子发生被免疫荧光组织化学在男睾丸观察。将近相同的 AFLP 侧面在男性和女性之间被观察,但是一男性特定 86 bp AFLP 碎片被性水池 bulked segregant 分析并且单个屏蔽屏蔽。基于男性特定的 AFLP 碎片, 579 个 bp 序列的一个总数被染色体走克隆。随后,一个男性特定的疤标记被设计,并且男性特定的 DNA 碎片被证实稳定地被传给下一代并且一致地仅仅在男性检测了。 | Da Wang Huiling Mao Jinxia Peng Xiyin Li Li Zhou Jianfang Gui | 2009 | Progress in Natural Science:Materials International2009，19，11： | 11 |
| 10 | Effects of Temperature and Catalyst to Oil Weight Ratio on the Catalytic Conversion of Heavy Oil to Propylene Using ZSM-5 and USY Catalysts显示文摘实际操作在 FCC 由重油的催化变换学习丙烯的生产的规则是有用的(液体催化裂开) 。产品的分发和丙烯的收益上的温度和 C/O 比率(给重量比率上油的催化剂) 的效果与二模型催化剂在一个微反应堆单位上被调查,也就是, ZSM-5/Al2O3 和 USY/Al2O3,和 Fushun 真空瓦斯油(VGO ) 被用作化工物品。在 ZSM-5 催化剂上的重油的变换能比得上在高温和高 C/O 比率的 USY 催化剂的。用 ZSM-5 平衡催化剂的重油的变换的率与在一般 FCC 条件下面的 USY 平衡催化剂相比是更低的,这能被归因于 ZSM-5 平衡催化剂的差的蒸气能力。在 USY 和 ZSM-5 的毛孔拓扑学的差别是为什么的原因为上述二催化剂的主要产品是不同的,也就是汽油和液体石油气体(LPG ) repspectively。那么 LPG 选择,特别丙烯选择,如果 USY 为最大化丙烯的生产被增加进 FCC 催化剂,可以衰退。增加 C/O 比率比二模型催化剂的温度的增加是为 LPG 产量的增加的最节俭的方法,因为轻油的损失是在以前的案例中的更少。在 HTC (氢转移系数) 和丙烯的收益之间有反的关联,并且限制氢转移反应是在增加 ZSM-5 催化剂的丙烯的收益的更重要的措施。ZSM-5/Al2O3 的乙烯收益更高,但是当 ZSM-5 催化剂被使用时,有低价值的气体的副产品没被提高。而且为 LPG 和结束产品,弄干气体和焦炭,他们他们的收益依赖的反应对条件的范围是不同的,并且结束产品的比 LPG 的更严重。最大化 LPG 和丙烯并且限制干燥气体和焦炭能是经由在产量对 LPG 敏感的反应条件的范围之中增加反应条件的严厉完成的两个,因此是清楚的。给词调音:液体催化裂开;重油;丙烯;温度;催化剂将给重量比率上油;ZSM-5; | Xiaohong Li Chunyi Li Jianfang Zhang Chaohe Yang Honghong Shan | 2007 | Journal of Natural Gas Chemistry2007，16，1： | 10 |
| 11 | Phenotypic and genetic variation between two populations of the Chinese yellow pond turtle, Mauremys mutica (Cantor, 1842)显示文摘Mauremys mutica(Cantor,1842)is an endangered species in China.Main phenotypic variations inbody color,body weight,body shape,clutch size,egg size,and hatchling size were revealed betweenthe southern and northern populations.Both populations have the phenomenon of'larger male'sexualsize dimorphism(SSD),especially in the southern population.Furthermore,genetic variations betweenthe two populations were analyzed by RAPD band patterns of 30 random individuals in each population.The average genetic distance was 0.299±0.108 among the samples of two populations.The average ge-netic distance between southern and northern populations was 0.305±0.046.Cluster analysis indicatedthat all the individuals from the southern and northern populations were clustered among themselves toform two distinct clades.A total of 20 population-specific RAPD fragments were scored from 16 primers,and could be used as RAPD markers for distinguishing the southern and the northern population.Basedon the nucleotide sequences of two RAPD markers,two pairs of SCAR primers(SC1-S and SC2-S)weredesigned,which could be used as SCAR markers for the southern population.According to the significantphenotypic and genetic variations,we suggested that the northern population and southern populationmight be considered as two separate taxa,the'northern taxon'and the'southern taxon',and the con-servation should be respectively conducted on the two taxa. | 朱新平 Zhou Li Chen Yongle Du Hejun Gui Jianfang | 2008 | High Technology Letters2008，14，1： | 10 |
| 12 | Potential targets for protecting against hippocampal cell apoptosis after transient cerebral ischemiareperfusion injury in aged rats显示文摘Mitochondria play an important role in neuronal apoptosis caused by cerebral ischemia, and the role is mediated by the expression of mitochondrial proteins. This study investigated the involvement of mitochondrial proteins in hippocampal cell apoptosis after transient cerebral ischemia-reperfusion injury in aged rats using a comparative proteomics strategy. Our experimental results show that the aged rat brain is sensitive to ischemia-reperfusion injury and that transient ischemia led to cell apoptosis in the hippocampus and changes in memory and cognition of aged rats. Differential proteomics analysis suggested that this phenomenon may be mediated by mitochondrial proteins associated with energy metabolism and apoptosis in aged rats. This study provides potential drug targets for the treatment of transient cerebral ischemia-reperfusion injury. | Xiangyu Ji Li'na Zhang Ran Liu Yingzhi Liu Jianfang Song He Dong Yanfang Jia Zangong Zhou | 2014 | Neural Regeneration Research2014，9，11： | 9 |
| 13 | Quaternary biogenic opal records in the South China Sea: Linkages to East Asian monsoon, global ice volume and orbital forcing显示文摘Particulate fluxes investigated in the central South China Sea (SCS) during 1993―1996 indicate that opal flux can be used to show primary productivity change, which provides a foundation for tracing the evolutionary relationship between the surface productivity and East Asian monsoon in the SCS during the late Quaternary glacial and interglacial periods. Based on the studies of opal % and their mass accumulation rates (MAR) at the six sites recovered from the SCS during the “Resolution” ODP Leg 184 and “Sonne” 95 cruise of the Sino-Germany cooperation, opal % and their MARs increased evidently in the northern sites since 470―900 ka, and they enhanced and reduced, respectively, during the glacial and interglacial periods. Whereas they increased obviously in the southern sites since 420―450 ka, and they augmented and declined, respectively, during the interglacial and glacial periods. The vari- ability in opal % and their MARs in the late Quaternary glacial cyclicity indicate the “seesaw” pattern of surface productivity in the SCS. The winter monsoon intensified during the glacial periods, surface productivity increased and decreased, respectively, in the northern and southern SCS. The summer monsoon strengthened during the interglacial periods, surface productivity increased and decreased, respectively, in the southern and northern SCS. The cross spectral analyses between the opal % in the northern and southern SCS during the Quaternary and global ice volume (δ 18O) and orbital forcing (ETP) indicate that the East Asian winter and summer monsoons could be ascribed to the different drive mechanisms. On the orbital time scale, the global ice volume change could be a dominant factor for the winter monsoon intension and temporal variations. As compared with the winter monsoon, the correlative summer solar radiation with the obliquity and precession in the Northern Hemisphere could be a mostly controlling factor for the summer monsoon intension and temporal variations. | WANG RuJian JIAN ZhiMin XIAO WenShen TIAN Jun LI JianRu CHEN RongHua ZHENG YuLong CHEN JianFang | 2007 | Science China Earth Sciences2007，50，5： | 9 |
| 14 | Variations in paleoproductivity and the environmental implications over the past six decades in the Changjiang Estuary显示文摘Total organic carbon and organic carbon stable isotope, biogenic silica, chlorin were measured from a high resolution sediment core to indicate the variation in paleoproductivity and the environmental implications over the past decades (1942 to 1997) in the Changjiang Estuary. Based on these biomarkers, the shift in the phytoplankton community structure in the past decades was discussed in response to the long-term variations in nutrient concentrations and nutrient ratios. The results showed that the δ 13 C values varied from –26.15‰ to –19.5‰, suggesting the combined organic carbon sources of riverine and marine organisms. Based on the biogenic proxies, paleoproductivity changes were categorized into three stages: low production before 1950; an increase in production with the dominance of diatoms during 1950 to 1980, consistent with increasing of nutrient concentrations; a decrease in production after 1980 when the diatom production decreased while the production of non-silicious phytoplankton increased due to high nutrient inputs, and high N/P and P/Si ratios in the Changjiang Estuary. The sedimentation records also indicated that the riverine organic carbon increased since 1980. | JIN Haiyan CHEN Jianfang WENG Huanxin LI Hongliang ZHANG Weiyan XU Jie BAI Youcheng WANG Kui | 2010 | Acta Oceanologica Sinica2010，29，3： | 8 |
| 15 | Phytoplankton composition and its ecological effect in subsurface cold pool of the northern Bering Sea in summer as revealed by HPLC derived pigment signatures显示文摘CHEMTAX analysis of high-performance liquid chromatography(HPLC) pigment was conducted to study phytoplankton community structure in the northern Bering Sea shelf, where a seasonal subsurface cold pool emerges. The results showed that fucoxanthin(Fuco) and chlorophyll a(Chl a) were the most abundant diagnostic pigments, with the integrated water column values ranging from 141 to 2 160 μg/m2 and 477 to 5 535 μg/m2, respectively. Moreover, a diatom bloom was identified at Sta. BB06 with the standing stock of Fuco up to 9 214 μg/m3. The results of CHEMTAX suggested that the phytoplankton community in the northern Bering Sea shelf was dominated by diatoms and chrysophytes with an average relative contribution to Chl a of 80% and 12%, respectively, followed by chlorophytes, dinoflagellates, and cryptophytes. Diatoms were the absolutely dominant algae in the subsurface cold pool with a relative contribution exceeding 90%, while the contribution of chrysophytes was generally higher in oligotrophic upper water. Additionally, the presence of a cold pool would tend to favor accumulation of diatom biomass and a bloom that occurred beneath the halocline would be beneficial to organic matter sinks, which suggests that a large part of the phytoplankton biomass would settle to the seabed and support a rich benthic biomass. | ZHUANG Yanpei JIN Haiyan LI Hongliang CHEN Jianfang WANG Bin CHEN Fajin BAI Youcheng LU Yong TIAN Shichao | 2014 | Acta Oceanologica Sinica2014，33，6： | 7 |
| 16 | The origin, diversification and adaptation of a major mangrove clade (Rhizophoreae) revealed by whole-genome sequencing显示文摘Mangroves invade some very marginal habitats for woody plants—at the interface between land and sea.Since mangroves anchor tropical coastal communities globally, their origin, diversification and adaptation are of scientific significance, particularly at a time of global climate change. In this study, a combination of single-molecule long reads and the more conventional short reads are generated from Rhizophora apiculata for the de novo assembly of its genome to a near chromosome level. The longest scaffold, N50 and N90 for the R. apiculata genome, are 13.3 Mb, 5.4 Mb and 1.0 Mb, respectively. Short reads for the genomes and transcriptomes of eight related species are also generated. We find that the ancestor of Rhizophoreae experienced a whole-genome duplication ~70 Myrs ago, which is followed rather quickly by colonization and species diversification. Mangroves exhibit pan-exome modifications of amino acid(AA) usage as well as unusual AA substitutions among closely related species. The usage and substitution of AAs, unique among plants surveyed, is correlated with the rapid evolution of proteins in mangroves. A small subset of these substitutions is associated with mangroves' highly specialized traits(vivipary and red bark) thought to be adaptive in the intertidal habitats. Despite the many adaptive features, mangroves are among the least genetically diverse plants, likely the result of continual habitat turnovers caused by repeated rises and falls of sea level in the geologically recent past. Mangrove genomes thus inform about their past evolutionary success as well as portend a possibly difficult future. | Shaohua Xu Ziwen He Zhang Zhang Zixiao Guo Wuxia Guo Haomin Lyu Jianfang Li Ming Yang Zhenglin Du Yelin Huang Renchao Zhou Cairong Zhong David E. Boufford Manuel Lerdau Chung-I Wu Norman C. Duke Suhua Shi | 2017 | National Science Review2017，4，5： | 7 |
| 17 | Thermal preference, thermal tolerance and the thermal dependence of digestive performance in two Phrynocephalus lizards (Agamidae), with a review of species studied显示文摘 | Yanfu QU Hong LI Jianfang GAO Xuefeng XU Xiang JI | 2011 | Current Zoology2011，57，6： | 7 |
| 18 | Variations in organic carbon loading of surface sediments from the shelf to the slope of the Chukchi Sea,Arctic Ocean显示文摘The content of organic carbon(OC) normalized to the specific surface area(SSA) of sediment is widely used to trace variations in OC loading(OC/SSA).This study presents observations of OC/SSA of surface sediments collected in the Chukchi Sea,a typical Arctic marginal sea.Shelf sediments exhibit much higher OC/SSA values than slope sediments in the study area.Compared with OC/SSA values reported from the East Siberian Shelf and Mackenzie River,the slope sediments possess lower OC loading.This abrupt decrease in OC/SSA is mostly related to the lower primary production on slope as well as possible oxidization processes.The results of linear regression analysis between OC and SSA indicate a sedimentary source rock for the OC in the Chukchi Sea sediments.Moreover,shelf sediments with low SSA possess a larger rock OC fraction than slope sediments do.The dataset of the present study enables a more thorough understanding of regional OC cycling in the Chukchi Sea. | LI Zhongqiao WANG Xinyi JIN Haiyan JI Zhongqiang BAI Youcheng CHEN Jianfang | 2017 | Acta Oceanologica Sinica2017，36，8： | 6 |
| 19 | Inorganic Carbon Parameters Responding to Summer Hypoxia Outside the Changjiang Estuary and the Related Implications显示文摘The eutrophication,hypoxia and coastal acidification are attracting more and more attention.In this study,inorganic carbon parameters,including dissolved inorganic carbon (DIC) ,total alkalinity (TA) and calculated partial pressure of CO2 (pCO2) ,obtained from a summer cruise in August,2009,were used to investigate their integrated response to biological processes accompanying the oxygen depletion in the areas off the Changjiang Estuary.According to the observations,the typical hypoxia occurred in the bottom water just outside the Changjiang Estuary with Dissolved Oxygen (DO) lower than 2.00 mg L 1.The biological uptake in the surface water and the decomposition of organic matter in the bottom water were fully coupled with each other.The high concentration of Chl_a (Chl_a=10.9μg L 1) and DO (9.25 mg L 1) ,profoundly decreased DIC concentration (1828μmol kg 1) and elevated pH (8.42) was observed in the surface water.The correspondingly increased DIC and depletion of oxygen were observed in the bottom water.The semi-quantitative analysis proved that the locally-produced phytoplankton,determined by primary productivity,was deposited to the bottom and contributed about 76%of total amount of the organic carbon decomposition in the bottom.However,in the bottom hypoxia (DO=2.05 mg L 1) area observed in the Southern Zhejiang coastal water,the responding patterns of inorganic carbon parameters deviated from the previous one.The expanding of Changjiang Diluted Water (CDW) ,the adding of Hangzhou Bay water (with high DIC concentration) and Coastal Current together modify the DIC background value in this area,and the local degeneration and upwelling process may also help to offset the local DIC removed by net biological uptake in surface water.In addition,when the mixing occurring in autumn,which may break the summer stratification,the excess release of high DIC in the bottom water to the subsurface water could have an important influence on coastal acidification and the CO2uptake capacity in this area. | WANG Bin CHEN Jianfang JIN Haiyan LI Hongliang XU Jie | 2013 | Journal of Ocean University of China2013，12，4： | 6 |
| 20 | CEACAM6 promotes tumor migration, invasion, and metastasis in gastric cancer显示文摘(CEACAM6 ) Carcinoembryonic 抗原相关的房间粘附分子 6 证明在许多 humancancers 的增加的表示,和它的在表示上与提高的移植被联系,侵略,并且在 vivo 转移。这里,我们报导 CEACAM6 在房间衬里的胃的癌症(GC ) 和肿瘤纸巾是起来调整的。在 MKN-45 和 SGC-7901 GC 房间的 Over-expressionof CEACAM6 在 athymic 老鼠在 vitro 和转移支持了移植和侵略,而 MKN-28 和 SNU-16 GC 房间的移植和侵略被 knockdownof CEACAM6 压制。当 CEACAM6 是 over-expressedin SGC-7901 房间时,我们也观察到类固醇受体激活剂(C-SRC ) phosphorylation 被增加。一起拿,这些结果建议 CEACAM6 在 GC 作为 oncoprotein 工作并且可以是 importantmetastatic biomarker 和治疗学的目标。 | Yunqiang Zhang Mingde Zang Jianfang Li Jun Ji Jianian Zhang Xiaolei Liu Ying Qu Liping Su Chen Li Yinyan Yu Zhenggang Zhu Bingya Liu Min yan | 2014 | Acta Biochimica et Biophysica Sinica2014，46，4： | 5 |
您所在的机构暂未开通此部分的功能，请联系管理员