|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Hybrid Material of Graphene and Poly(3,4-ethyldioxythiophene)with High Conductivity,Flexibility,and Transparency显示文摘A novel hybrid material prepared from graphene and poly(3,4-ethyldioxythiophene)(PEDOT)shows excellent transparency,electrical conductivity,and good flexibility,together with high thermal stability and is easily processed in both water and organic solvents.Conductivities of the order of 0.2 S/cm and light transmittance of greater than 80%in the 4001800 nm wavelength range were observed for fi lms with thickness of tens of nm.Practical applications in a variety of optoelectronic devices are thus expected for this transparent and flexible conducting graphene-based hybrid material。 | Yanfei Xu Yan Wang Jiajie Liang Yi Huang Yanfeng Ma Xiangjian Wan Yongsheng Chen | 2009 | Nano Research2009，2，4： | 23 |
| 2 | 5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages显示文摘5-Hydroxymethylcytosine (5hmC ) 是被连接了到基因规定和癌症致病的重要哺乳动物的 DNA epigenetic 修正。这里,我们用定序途径的一枝敏感化学基于标签的低输入的猎枪在传播没有房间的 DNA (cfDNA ) 探索了 5hmC 的诊断潜力。我们从七种不同癌症类型的 49 个病人定序没有房间的 5hmC 并且发现了能被用来与高精确性预言癌症类型和阶段的不同特征。明确地,我们发现肺癌症在 cfDNA 导致 5hmC 的进步全球损失,而 hepatocellular 癌和胰腺的癌症在没有房间的 hydroxymethylome 导致疾病特定的变化。我们的 proof-of-principle 结果建议没有房间的 5hmC 签名可以潜在地被使用不仅识别癌症类型而且在一些癌症追踪肿瘤舞台。 | Chun-Xiao Song Senlin Yin Li Ma Amanda Wheeler Yu Chen Yan Zhang Bin Liu Junjie Xiong Weihan Zhang Jiankun Hu Zongguang Zhou Biao Dong Zhiqi Tian Stefanie S Jeffrey Mei-Sze Chua Samuel So Weimin Li Yuquan Wei Jiajie Diao Dan Xie Stephen R Quake | 2017 | Cell Research2017，27，10： | 17 |
| 3 | Coinfection with influenza A virus enhances SARS-CoV-2 infectivity显示文摘The upcoming flu season in the Northern Hemisphere merging with the current COVID-19 pandemic raises a potentially severe threat to public health.Through experimental coinfection with influenza A virus(IAV)and either pseudotyped or live SARS-CoV-2 virus,we found that IAV preinfection significantly promoted the infectivity of SARS-CoV-2 in a broad range of cell types.Remarkably,in vivo,increased SARS-CoV-2 viral load and more severe lung damage were observed in mice coinfected with IAV.Moreover,such enhancement of SARS-CoV-2 infectivity was not observed with several other respiratory viruses,likely due to a unique feature of IAV to elevate ACE2 expression.This study illustrates that IAV has a unique ability to aggravate SARS-CoV-2 infection,and thus,prevention of IAV infection is of great significance during the COVID-19 pandemic. | Lei Bai Yongliang Zhao Jiazhen Dong Simeng Liang Ming Guo Xinjin Liu Xin Wang Zhixiang Huang Xiaoyi Sun Zhen Zhang Lianghui Dong Qianyun Liu Yucheng Zheng Danping Niu Min Xiang Kun Song Jiajie Ye Wenchao Zheng Zhidong Tang Mingliang Tang Yu Zhou Chao Shen Li Zhou Yu Chen Huan Yan Ke Lan Ke Xu | 2021 | Cell Research2021，31，4： | 16 |
| 4 | THERMAL RATE TREATMENT AND ITS EFFECT ON MODIFICATION OF Al-Si ALLOYS显示文摘THERMALRATETREATMENTANDITSEFFECTONMODIFICATIONOFAlSiALLOYS①GengHaoran,MaJiaji,BianXoufangCollegeofMaterialsScienceandEnginer... | Geng, Haoran Ma, Jiaji Bian, Xoufang | 1997 | 中国有色金属学会会刊:英文版1997，7，1： | 15 |
| 5 | 2D sparse signal recovery via 2D orthogonal matching pursuit显示文摘Recovery algorithms play a key role in compressive sampling (CS).Most of current CS recovery algo-rithms are originally designed for one-dimensional (1D) signal,while many practical signals are two-dimensional (2D).By utilizing 2D separable sampling,2D signal recovery problem can be converted into 1D signal recovery problem so that ordinary 1D recovery algorithms,e.g.orthogonal matching pursuit (OMP),can be applied directly.However,even with 2D separable sampling,the memory usage and complexity at the decoder are still high.This paper develops a novel recovery algorithm called 2D-OMP,which is an extension of 1D-OMP.In the 2D-OMP,each atom in the dictionary is a matrix.At each iteration,the decoder projects the sample matrix onto 2D atoms to select the best matched atom,and then renews the weights for all the already selected atoms via the least squares.We show that 2D-OMP is in fact equivalent to 1D-OMP,but it reduces recovery complexity and memory usage significantly.What's more important,by utilizing the same methodology used in this paper,one can even obtain higher dimensional OMP (say 3D-OMP,etc.) with ease. | FANG Yong WU JiaJi HUANG BorMin | 2012 | Science China(Information Sciences)2012，55，4： | 14 |
| 6 | Endometrial membrane organoids from human embryonic stem cell combined with the 3D Matrigel for endometrium regeneration in asherman syndrome显示文摘Asherman’s syndrome(AS),a leading cause of uterine infertility worldwide,is characterized by scarring of the uterine surfaces lacking endometrial epithelial cells,which prevents endometrial regeneration.Current research on cell therapy for AS focuses on mesenchymal and adult stem cells from the endometrium.However,insufficient number,lack of purity,and rapid senescence of endometrial epithelial progenitor cells(EEPCs)during experimental processes restrict their use in cell therapies.In this study,we induced human embryonic stem cells-9(H9-ESC)into EEPCs by optimizing the induction factors from the definitive endoderm.EEPCs,which act as endometrial epithelial cells,accompanied by human endometrial stromal cells provide a niche environment for the development of endometrial membrane organoids(EMOs)in an in vitro 3D culture model.To investigate the function of EMOs,we transplanted tissue-engineered constructs with EMOs into an in vivo rat AS model.The implantation of EMOs into the damaged endometrium facilitates endometrial regeneration and angiogenesis.Implanting EMOs developed from human embryonic stem cells into the endometrium might prove useful for“endometrial re-engineering”in the treatment of Asherman’s syndrome. | Xiuxiu Jiang Xingmiao Li Xiangwei Fei Jiajie Shen Jianhua Chen Meijun Guo Yangyang Li | 2021 | Bioactive Materials2021，6，11： | 11 |
| 7 | Late Silurian to Early Devonian Palynomorphs from Qujing,Yunnan,Southwest China显示文摘保存得很好、多样化的孢子, cryptospores,和 acritarchs 从在 Qujing 包含 SilurianDevonian 边界的一个相对连续的序列被记录了,云南,西南中国。到在年龄的早泥盆纪的从迟了的志留纪的四个孢子集合地区基于典型孢子种类的第一本外观资料(一度时髦的风尚) 被建议。在登上 stratigraphic 顺序,他们是 Ambitisporites dilutusApiculiretusispora synorea (DS;迟了的 Ludfordian 到早 Pridoli ) , Synorisporites verrucatusApiculiretusispora plicata (VP;Pridoli ) , Apiculiretusispora minutaLeiotriletes ornatus (瞬间;Lochkovian ) ,并且 Verrucosisporites polygonalisDibolisporites wetteldorfensis (PW;Pragian ) 。从 Yulongsi 形成, Xiaxishancun 形成,和 Xitun 形成的 lowermiddle 部分的上面的部分的 acritarch 集合近来显示年龄志留纪。把证据基于 palynological, Yulongsi 形成的上面的部分在年龄被认为 Ludfordian 迟了到早 Pridoli;Xiaxishancun 形成被相信是在年龄的 Pridoli;Xitun 形成在年龄被认为 Pridoli 迟了到早 Lochkovian;Guijiatun 形成在年龄被认为 Lochkovian;并且 Xujiachong 形成是到在年龄的 Pragian 的迟了的 Lochkovian。志留纪泥盆纪边界在 VP 和 MO 孢子 biozones 之间被认出,并且发生在 Xitun 形成的中间的部分以内。 | TIAN Jiajie ZHU Huaicheng HUANG Min LIU Feng | 2011 | Acta Geologica Sinica(English Edition)2011，85，3： | 10 |
| 8 | Technological development and engineering applications of novel steel-concrete composite structures显示文摘In view of China's development trend of green building and building industrialization,based on the emerging requirements of the structural engineering community,the development and proposition of novel resourcesaving high-performance steel-concrete composite structural systems with adequate safety and durability has become a kernel development trend in structural engineering.This paper provides a state of the art review of China's cutting-edge research and technologies in steel-concrete composite structures in recent years,including the building engineering,the bridge engineering and the special engineering.This paper summarizes the technical principles and applications of the long-span bi-directional composite structures,the long-span composite transfer structures,the comprehensive crack control technique based on uplift-restricted and slip-permitted (URSP)connectors,the steel plate concrete composite (SPCC)strengthen technique,and the innovative composite joints.By improving and revising traditional structure types, the comprehensive superiority of steel-concrete composite structures is well elicited.The research results also indicate that the high-performance steel-concrete composite structures have a promising popularizing prospect in the future. | Jianguo NIE Jiaji WANG Shuangke GOU Yaoyu ZHU Jiansheng FAN | 2019 | Frontiers of Structural and Civil Engineering2019，13，1： | 9 |
| 9 | An efficient visible-light photocatalyst for CO2 reduction fabricated by cobalt porphyrin and graphitic carbon nitride via covalent bonding显示文摘Nanoparticle photosensitizers possess technical advantages for photocatalytic reactions due to enhanced light harvesting and efficient charge transport.Here we report synthesis of semiconductor nanoparticles through covalent coupling and assembly of metalloporphyrin with condensed carbon nitride.The resultant nanoparticles consist of light harvesting component from the condensed carbon nitride and photocatalytic sites from the metalloporphyrins.This synergetic particle system effectively initiates efficient charge separation and transport and exhibits excellent photocatalytic activity for CO2 reduction.The CO production rate can reach up to 57μmol/(g·h)with a selectivity of 79%over competing H2 evolution.Controlled experiments demonstrate that the combination of light harvesting with photocatalytic activity via covalent assembly is crucial for the high photocatalytic activity.Due to effective charge separation and transfer,the resultant nanoparticle photocatalysts show exceptional photo stability against photo-corrosion under light irradiation,enabling for long-term utilization.This research opens a new way for the development of stable,effective nanoparticle photocatalysts using naturally abundant porphyrin pigments. | Shufang Tian Sudi Chen Xitong Ren Yaoqing Hu Haiyan Hu Jiajie Sun Feng Bai | 2020 | Nano Research2020，13，10： | 9 |
| 10 | Attenuated Listeria monocytogenes as a cancer vaccine vector for the delivery of CD24, a biomarker for hepatic cancer stem cells显示文摘稀释 Listeria monocytogenes (LM ) 是为癌症疫苗的交货的有希望的候选人向量。在由介绍抗原的房间的吞噬作用以后,这个细菌刺激主要 histocompatibility 建筑群(MHC ) 我和 MHC-II 小径并且导致抗原特定的 T 淋巴细胞的增长。包含复制缺乏的 LM 种类 Δ 的基因修正的新策略; dalΔ dat (Lmdd ) 被开发了表示并且藏匿人的 CD24 蛋白质。CD24 是仔细与 hepatocellular 癌(HCC ) 的 apoptosis,转移和复发被联系的肝的癌症干细胞 biomarker。在在老鼠的静脉内的管理以后, Lmdd-CD24 首先在怒气和肝被散布并且没引起严重机关损害。Lmdd-CD24 有效地增加了干扰素(IFN ) 的数字 -γ-producing CD8 + T 房间和 IFN-γ分泌物。Lmdd-CD24 也提高了 IL-4- 和 IL-10-producing T 助手 2 房间的数字。Lmdd-CD24 疫苗的功效进一步对 Hepa1-6-CD24 肿瘤被调查,它腹股沟地被接种进老鼠。Lmdd-CD24 显著地在老鼠减少了肿瘤尺寸并且增加了他们的幸存。尤其是, T 规章的房间(Treg ) 的减小数并且特定的 CD8 +T 房间活动的改进在渗入肿瘤的淋巴细胞(TIL ) 被观察。这些结果对 HCC 建议 Lmdd-CD24 疫苗的一个潜在的应用程序。 | Yu Yang Jiajie Hou Zhe Lin Han Zhuo DianyuChen Xudong Zhang Yun Chen Beicheng Sun | 2014 | Cellular & Molecular Immunology2014，11，2： | 9 |
| 11 | Prediction of Cross-Tension Strength of Self-Piercing Riveted Joints Using Finite Element Simulation and XGBoost Algorithm显示文摘Self-piercing riveting(SPR)has been widely used in automobile industry,and the strength prediction of SPR joints always attracts the attention of researchers.In this work,a prediction method of the cross-tension strength of SPR joints was proposed on the basis of finite element(FE)simulation and extreme gradient boosting decision tree(XGBoost)algorithm.An FE model of SPR process was established to simulate the plastic deformations of rivet and substrate materials and verified in terms of cross-sectional dimensions of SPR joints.The residual mechanical field from SPR process simulation was imported into a 2D FE model for the cross-tension testing simulation of SPR joints,and cross-tension strengths from FE simulation show a good consistence with the experiment result.Based on the verified FE model,the mechanical properties and thickness of substrate materials were varied and then used for FE simulation to obtain cross-tension strengths of a number of SPR joints,which were used to train the regression model based on the XGBoost algorithm in order to achieve prediction for cross-tension strength of SPR joints.Results show that the cross-tension strengths of SPR steel/aluminum joints could be successfully predicted by the XGBoost regression model with a respective error less than 7.6%compared to experimental values. | Jianping Lin Chengwei Qi Hailang Wan Junying Min Jiajie Chen Kai Zhang Li Zhang | 2021 | Chinese Journal of Mechanical Engineering2021，34，2： | 8 |
| 12 | Flexible and stretchable electrodes for next generation polymer electronics: a review显示文摘Transparent conductive electrodes play a significant role in the fabrication and development of optoelectronic devices. As next generation optoelectronic devices tend towards mobile and wearable devices, the added attribute of flexibility or stretchability for these electrodes becomes increasingly important. However, mechanical requirements aside, transparent conductive electrodes must still retain high transparency and conductivity, with the metrics for these parameters being compared to the standard, indium tin oxide. In the search to replace indium tin oxide, two materials that have risen to the forefront are carbon nanotubes and silver nanowires due to their high transparency, conductivity, mechanical compliance, and ease of fabrication. This review highlights recent innovations made by our group in electrodes utilizing carbon nanotubes and silver nanowires, in addition to the use of these electrodes in discrete devices and integrated systems. | Dustin Chen Jiajie Liang Qibing Pei | 2016 | Science China Chemistry2016，59，6： | 8 |
| 13 | Optical tuning of exciton and trion emissions in monolayer phosphorene显示文摘Monolayer phosphorene provides a unique two-dimensional(2D)platform to investigate the fundamental dynamics of excitons and trions(charged excitons)in reduced dimensions.However,owing to its high instability,unambiguous identification of monolayer phosphorene has been elusive.Consequently,many important fundamental properties,such as exciton dynamics,remain underexplored.We report a rapid,noninvasive,and highly accurate approach based on optical interferometry to determine the layer number of phosphorene,and confirm the results with reliable photoluminescence measurements.Furthermore,we successfully probed the dynamics of excitons and trions in monolayer phosphorene by controlling the photo-carrier injection in a relatively low excitation power range.Based on our measured optical gap and the previously measured electronic energy gap,we determined the exciton binding energy to be~0.3 eV for the monolayer phosphorene on SiO_(2)/Si substrate,which agrees well with theoretical predictions.A huge trion binding energy of~100 meV was first observed in monolayer phosphorene,which is around five times higher than that in transition metal dichalcogenide(TMD)monolayer semiconductor,such as MoS_(2).The carrier lifetime of exciton emission in monolayer phosphorene was measured to be,220 ps,which is comparable to those in other 2D TMD semiconductors.Our results open new avenues for exploring fundamental phenomena and novel optoelectronic applications using monolayer phosphorene. | Jiong Yang Renjing Xu Jiajie Pei Ye Win Myint Fan Wang Zhu Wang Shuang Zhang Zongfu Yu Yuerui Lu | 2015 | Light(Science & Applications)2015，4，1： | 8 |
| 14 | In situ plasmonic optical fiber detection of the state of charge of supercapacitors for renewable energy storage显示文摘In situ and continuous monitoring of electrochemical activity is key to understanding and evaluating the operation mechanism and efficiency of energy storage devices.However,this task remains challenging.For example,the present methods are not capable of providing the real-time information about the state of charge(SOC)of the energy storage devices while in operation.To address this,a novel approach based on an electrochemical surface plasmon resonance(SPR)optical fiber sensor is proposed here.This approach offers the capability of in situ comprehensive monitoring of the electrochemical activity(the electrode potential and the SOC)of supercapacitors(used as an example).The sensor adopted is a tilted fiber Bragg grating imprinted in a commercial single-mode fiber and coated with a nanoscale gold film for high-efficiency SPR excitation.Unlike conventional“bulk”detection methods for electrode activity,our approach targets the“localized”(sub-μm-scale)charge state of the ions adjacent to the electrode interface of supercapacitors by monitoring the properties of the SPR wave on the fiber sensor surface located adjacent to the electrode.A stable and reproducible correlation between the real-time charge–discharge cycles of the supercapacitors and the optical transmission of the optical fiber has been found.Moreover,the method proposed is inherently immune to temperature cross-talk because of the presence of environmentally insensitive reference features in the optical transmission spectrum of the devices.Finally,this particular application is ideally suited to the fundamental qualities of optical fiber sensors,such as their compact size,flexible shape,and remote operation capability,thereby opening the way for other opportunities for electrochemical monitoring in various hard-to-reach spaces and remote environments. | Jiajie Lao Peng Sun Fu Liu Xuejun Zhang Chuanxi Zhao Wenjie Mai Tuan Guo Gaozhi Xiao Jacques Albert | 2018 | Light(Science & Applications)2018，7，1： | 8 |
| 15 | Pre-peak on the structure factor of liquid hypoeutectic Al-Fe alloy显示文摘Using a θ-θ X ray diffractometer the structure of liquid hypoeutectic Al Fe alloy at 675℃ and its change with different thermal histories are investigated . Liquid Al is used as a reference system. It is found that a pre peak appears on the small angle part of the structure factor of the nonsuperheated hypoeutectic Al Fe alloy, but disappears after superheating whereas the structure factors of liquid Al hardly change with the different thermal histories, and no pre peak can be observed on them. The appearance of a pre peak is a mark of the intermediate range order (IRO). The pre peak is taken as the correlation between Fe atoms on the IRO length scale. Assume that the crystalline structure is the first order approximation of the liquid structure. A model structure is constructed. The basic unit is a cube formed by 8 Al atoms on its corner and one Fe atom occupying its center. The translation of such a unit along its fourbody diagonals by the length of a diagonal can meet the requirement of the Fe_Fe distance and gives a DO 3 like structure. If the vacancy among the units is filled with fcc like Al cells, the composition of the entity is about Al 7Fe, close to that of the metastable phase Al 6Fe from rapid solidification. It is speculated that there are Al 6Fe like clusters in the liquid hypoeutectic Al Fe alloy. | Jingyu Qin Xiufang Bian Weimin Wang Jiaji Ma Changye Xu | 1998 | Chinese Science Bulletin1998，43，14： | 7 |
| 16 | A Review on Self-Recovery Regulation(SR)Technique for Unbalance Vibration of High-End Equipment显示文摘The high-end equipment represented by high-end machine tools and aero-engines is the core component of the national intelligent manufacturing plan,and the mass unbalance is the main reason for its excessive vibration,that seriously impacts the operation efficiency and running life of the equipment.In order to change the traditional way that the fault of equipment can only be repaired by human,the self-recovery mechanism of human and animal are given to the equipment in this paper,which forms the self-recovery regulation(SR)system for unbalance vibration of high-end equipment.The system can online generate the self-recovery force to restrain the unbalance vibration of the equipment in operation,which is an important direction for the development of the equipment to the advanced intelligent stage.Based on the basic principles of SR technique,the typical engineering application cases of this technique in the field of aeroengine and high-end machine tools are introduced,and four related studies promoting the development of this technique are summarized and analyzed in turn.It includes feature extraction,imbalance location,regulation method and balancing actuator.Self-recovery Regulation(SR)Technique is an important way to realize intelligent manufacturing and intelligent maintenance.Relevant research can lay a technical foundation for the development of high-end equipment with self-health function. | Xin Pan Jiaqiao Lu Jiaji Huo Jinji Gao Haiqi Wu | 2020 | Chinese Journal of Mechanical Engineering2020，33，6： | 7 |
| 17 | Step-scheme CdS/TiO_(2) nanocomposite hollow microsphere with enhanced photocatalytic CO_(2) reduction activity显示文摘Converting solar energy into chemical energy by artificial photosynthesis is promising in addressing the issues of the greenhouse effect and fossil fuel crisis.Herein,a novel photocatalyst,i.e.CdS/TiO_(2) hollow microspheres(HS),were dedicatedly designed to boost overall photocatalytic efficiency.TiO_(2) nanoparticles were in-situ decorated on the inside and outside the shell of Cd S HS,ensuring close contact between TiO_(2) and CdS.The CdS/TiO2 HS with abundant mesopores inside of the shell boost the light absorption via multiscattering effect as well as accessible to reactions in all directions.The heterojunction was scrutinized and the charge transfer across it was revealed by in-situ irradiated X-ray photoelectron spectroscopy(ISI-XPS).Ultimately,the charge transfer in this composite was determined to follow stepscheme mechanism,which not only facilitates the separation of charge carriers but also preserves strong redox ability.Benefited from the intimate linkage between Cd S and TiO_(2) and the favorable step-scheme heterojunction,enhanced photocatalytic CO_(2) reduction activity was accomplished.The CH4 yield rate of CdS/TiO_(2) reaches 27.85μmol g^(–1) h^(–1),which is 145.6 and 3.8 times higher than those of pristine CdS and TiO_(2),respectively.This work presents a novel insight into constructing step-scheme photocatalytic system with desirable performance. | Zhongliao Wang Yifan Chen Liuyang Zhang Bei Cheng Jiaguo Yu Jiajie Fan | 2020 | Journal of Materials Science & Technology2020，56，21： | 7 |
| 18 | Toxic effects of arsenic trioxide on Echinococcus granulosus protoscoleces through ROS production, and Ca^2+-ER stress-dependent apoptosis显示文摘 | Jiajie Li Guangyao Tang Wenjuan Qin Rentan Yang Rongji Ma Bin Ma Jianfeng Wei Hailong Lv Yufeng Jiang | 2018 | Acta Biochimica et Biophysica Sinica2018，50，6： | 6 |
| 19 | Hetero-phase MoC-Mo_(2)C nanoparticles for enhanced photocatalytic H_(2)-production activity of TiO_(2)显示文摘Hexagonal molybdenum carbide(Mo_(2)C)as an effective non-noble cocatalyst is intensively researched in the photocatalytic H_(2)-evolution field owing to its Pt-like H^(+)-adsorption ability and good conductivity.However,hexagonal Mo_(2)C-modified photocatalysts possess a limited H_(2)-evolution rate because of the weak H-desorption ability.Tofurther improve the activity,cubic MoC was introduced into Mo_(2)C toform the carbon-modified MoC-Mo_(2)C nanoparticles(MoC-Mo_(2)C@C)by a calcination method.The resultant MoC-Mo_(2)C@C(ca.5 nm)was eventually coupled with Ti0_(2)to acquire high-efficiency Ti0_(2)/MoC-Mo_(2)C@C by electrostatic self-assembly.The highest H_(2)-generation rate of Ti0_(2)/MoC-Mo_(2)C@C reached of 918μmol·h^(-1)·g^(-1)which was 91.8,2.7,and 1.5 times than that of the Ti0_(2),TiO_(2)/MoC@C,and Ti0_(2)/Mo_(2)C@C,respectively.The enhanced rate of Ti0_(2)attributes to the carbon layer as cocatalyst to transmit electrons and the hetero-phase MoC-Mo_(2)C as H_(2)-generation active sites to boost H_(2)-evolution reaction.This research offers a novel insight to design photocatalytic materials for energy applications. | Jinfeng Liu Ping Wang Jiajie Fan Huogen Yu Jiaguo Yu | 2021 | Nano Research2021，14，4： | 6 |
| 20 | High-speed in vitro intensity diffraction tomography显示文摘We demonstrate a label-free,scan-free intensity diffraction tomography technique utilizing annular illumination(aIDT)to rapidly characterize large-volume three-dimensional(3-D)refractive index distributions in vitro.By optimally matching the illumination geometry to the microscope pupil,our technique reduces the data requirement by 60 times to achieve high-speed 10-Hz volume rates.Using eight intensity images,we recover volumes of∼350μm×100μm×20μm,with near diffraction-limited lateral resolution of∼487 nm and axial resolution of∼3.4μm.The attained large volume rate and high-resolution enable 3-D quantitative phase imaging of complex living biological samples across multiple length scales.We demonstrate aIDT’s capabilities on unicellular diatom microalgae,epithelial buccal cell clusters with native bacteria,and live Caenorhabditis elegans specimens.Within these samples,we recover macroscale cellular structures,subcellular organelles,and dynamic micro-organism tissues with minimal motion artifacts.Quantifying such features has significant utility in oncology,immunology,and cellular pathophysiology,where these morphological features are evaluated for changes in the presence of disease,parasites,and new drug treatments.Finally,we simulate the aIDT system to highlight the accuracy and sensitivity of the proposed technique.aIDT shows promise as a powerful high-speed,label-free computational microscopy approach for applications where natural imaging is required to evaluate environmental effects on a sample in real time. | Jiaji Li Alex Matlock Yunzhe Li Qian Chen Chao Zuo Lei Tian | 2019 | Advanced Photonics2019，1，6： | 6 |
您所在的机构暂未开通此部分的功能，请联系管理员