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| 1 | 虚拟 nonenhanced 腹的双精力的 MDCT : 图象特征的分析显示文摘 AIM:To evaluate abdominal and pelvic image characteristics and artifacts on virtual nonenhanced(VNE) images generated from contrast-enhanced dual-energy multidetector computed tomography(MDCT)studies.METHODS:Hadassah-Hebrew University Medical Institutional Review Board approval was obtained;22 patients underwent clinically-indicated abdominal and pelvic single-source dual-energy MDCT(Philips Healthcare,Cleveland,OH,USA),pre-and post-IV administration of Omnipaque 300 contrast(100 cc).Various solid and vascular structures were evaluated.VNE images were generated from the portal contrast-enhanced phase using probabilistic separation.Contrast-enhanced-,regular nonenhanced(RNE)-,and VNE images were evaluated with a total of 1494 density measurements.The ratio of iodine contrast deletion was calculated.Visualization of calcifications,urinary tract stones,and image artifacts in VNE images were assessed.RESULTS:VNE images were successfully generated in all patients.Significant portal-phase iodine contrast deletion was seen in the kidney(61.7%),adrenal gland(55.3%),iliac artery(55.0%),aorta(51.6%),and spleen(34.5%).Contrast deletion was also significant in the right atrium(RA)(51.5%)and portal vein(39.3%),but insignificant in the iliac vein and inferior vena cava(IVC).Average post contrast-to-VNE HU differences were significant(P<0.05)in the:RA-135.3(SD 121.8),aorta-114.1(SD 48.5),iliac artery-104.6(SD 53.7),kidney-30.3(SD 34.9),spleen-9.2(SD 8.8),and portal vein-7.7(SD 13.2).Average VNE-toRNE HU differences were significant in all organs but the prostate and subcutaneous fat:aorta 38.0(SD 9.3),RA 37.8(SD 16.1),portal vein 21.8(SD 12.0),IVC 12.2(SD 11.6),muscle 3.3(SD 4.9),liver 5.7(SD 6.4),spleen 22.3(SD 9.8),kidney 40.5(SD 6.8),and adrenal 20.7(SD 13.5).On VNE images,196/213 calcifications(92%)and 5/6 renal stones(84%)were visualized.Lytic-like artifacts in the vertebral bodies were seen in all studies.CONCLUSION:Iodine deletion in VNE images is most significant in arteries,and less significant in solid organs and veins.Most vascular and intra-abdominal organ calcifications are preserved. | Jacob Sosna Shmuel Mahgerefteh Liran Goshen Galit Kafri Galit Aviram Arye Blachar | 2012 | World Journal of Radiology2012，4，4： | 4 |
| 2 | Liver Lesions With Hepatic Capsular Retraction显示文摘 | Arye Blachar Michael P. Federle Jacob Sosna | 2009 | Seminars in Ultrasound, CT, and MRI2009，，5： | 1 |
| 3 | Factors associated with surgery in patients with intra-abdominal fistulizing Crohn's disease显示文摘AIM To characterize radiological and clinical factors associated with subsequent surgical intervention in Crohn's disease(CD) patients with intra-abdominal fistulae.METHODS From a cohort of 1244 CD patients seen over an eight year period(2006 to 2014), 126 patients were identified as having intra-abdominal fistulae, and included in the study. Baseline patient information was collected from the medical records. Imaging studies were assessed for: anatomic type and number of fistulae; diameter of the inflammatory conglomerate; length of diseased bowel; presence of a stricture with pre-stenotic dilatation; presence of an abscess; lymphadenopathy; and the degree of bowel enhancement. Multivariate analysis for the prediction of abdominal surgery was calculated via Generalized Linear Models.RESULTS In total, there were 193 fistulae in 132 patients, the majority(52%) being entero-enteric. Fifty-nine(47%) patients underwent surgery within one year of the imaging study, of which 36(29%) underwent surgery within one month. Radiologic features that were associated with subsequent surgery included: multiple fistulae(P = 0.009), presence of stricture(P = 0.02), and an entero-vesical fistula(P = 0.01). Evidence of an abscess, lymphadenopathy, or intense bowel enhancement as well as C-reactive protein levels was not associated with an increased rate of surgery. Patients who were treated after the imaging study with combination immunomodulatory and anti-TNF therapy had significantly lower rates of surgery(P = 0.01). In the multivariate analysis, presence of a stricture [RR 4.5(1.23-16.3), P = 0.02] was the only factor that increased surgery rate.CONCLUSION A bowel stricture is the only factor predicting an increased rate of surgery. Radiological parameters may guide in selecting treatment options in patients with fistulizing CD. | Shaul Yaari Ariel Benson Eyal Aviran Naama Lev Cohain Ran Oren Jacob Sosna Eran Israeli | 2016 | World Journal of Gastroenterology2016，22，47： | 1 |
| 4 | Enigma of primary aortoduodenal fistula显示文摘A diagnosis of primary aortoenteric fistula is difficult to make despite a high level of clinical suspicion. It should be considered in any elderly patient who presents with upper gastrointestinal bleeding in the context of a known abdominal aortic aneurysm. We present the case of young man with no history of abdominal aortic aneurysm who presented with massive upper gastrointestinal bleeding. Initial misdiagnosis led to a delay in treatment and the patient succumbing to the illness. This case is unique in that the fistula formed as a result of complex atherosclerotic disease of the abdominal aorta, and not from an aneurysm. | Miklosh Bala Jacob Sosna Liat Appelbaum Eran Israeli Avraham I Rivkind | 2009 | World Journal of Gastroenterology2009，15，25： | 1 |
| 5 | Intraoper- ative sonography for neurosurgery显示文摘 | Jacob Sosna Mara M Barth Jonathan B Kruskal | 2005 | Ultrasound Med2005，24，： | 1 |
| 6 | Accessory spleen-like masses in oncology patients:Are they always benign?显示文摘AIM:To assess retrospectively the significance of accessory spleen-like mass(ASLM) in oncology patients undergoing positron emission tomography/computed tomography(PET/CT).METHODS:The results of PET/CT of 913 patients(278 lymphoma;635 solid tumors) were reviewed.The number,size,location and attenuation of all ASLMs,and spleen attenuation,were recorded.ASLM fluorodeoxyglucose uptake was graded as normal(less than or equal to that in the liver) or representative of malignancy(more than in the liver).Follow-up PET/CT in patients with ASLM was reviewed when available.ASLM size and attenuation for spleen and ASLM were compared by unpaired Student's t test.The χ2 and Fisher's exact tests were used to compare ASLM frequency and uptake for lymphomatous and solid tumors,respectively.RESULTS:ASLM frequency was 14.8,with 152 ASLMs found in 135 patients.Mean attenuation was lower in ASLM compared with spleen by enhanced and nonenhanced CT(80.7 ± 20.4 HU vs 92.0 ± 14.4 HU,P < 0.0011 and 42.3 ± 9.0 HU vs 51.5 ± 6.3 HU,P < 0.0001,respectively).ASLM incidence was higher in lymphoma patients(56/278,20.1) than in those with solid tumors(56/278,20.1 vs 79/635,12.4,P = 0.0036).Pathological uptake was found in four(7.1) lymphoma patients but not in any patients with a solid tumor(P = 0.028) and it upstaged one patient with lymphoma.Follow-up PET/CT within 3-16 mo was available in 54 of patients with ASLM.Lesion regression was noted in all four pathological ASLMs on follow-up PET/CT after chemotherapy.CONCLUSION:In patients with lymphoma,ASLM can represent malignancy,and thus further characterization with PET/CT might be warranted.Patients with neoplasia other than ASLM can be confidently diagnosed with accessory spleen. | David Groshar Hanna Bernstine Natalia Goldberg Dorit Stern Jacob Sosna | 2010 | World Journal of Radiology2010，2，9： | 0 |
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