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| 1 | Pretreated Oenan the Javanica extract increases anti-inflammatory cytokines, attenuates gliosis, and protects hippocampal neurons following transient global cerebral ischemia in gerbils显示文摘Recently,we have reported that Oenanthe javanica extract(OJE)displays strong neuroprotective effect against ischemic damage after transient global cerebral ischemia.However,neuroprotective mechanisms of OJE have not been fully identified.Thus,this study investigated the neuroprotection of OJE in the hippocampal CA1 area and its anti-inflammatory activity in gerbils subjected to 5 minutes of transient global cerebral ischemia.We treated the animals by intragastrical injection of OJE(100 and 200 mg/kg)once daily for 1 week prior to transient global cerebral ischemia.Neuroprotection of OJE was observed by immunohistochemistry for neuronal nuclear antigen and histofluorescence staining for Fluoro-Jade B.Immunohistochemistry of glial fibrillary acidic protein and ionized calcium-binding adapter molecule 1 was done for astrocytosis and microgliosis,respectively.To investigate the neuroprotective mechanisms of OJE,we performed immunohistochemistry of tumor necrosis factor-alpha and interleukin-2 for pro-inflammatory function and interleukin-4 and interleukin-13 for anti-inflammatory function.When we treated the animals by intragastrical administration of 200 mg/kg of OJE,hippocampal CA1 pyramidal neurons were protected from transient global cerebral ischemia and cerebral ischemia-induced gliosis was inhibited in the ischemic hippocampal CA1 area.We also found that interleukin-4 and-13 immunoreactivities were significantly increased in pyramidal neurons of the ischemic CA1 area after OJE pretreatment,and the increased immunoreactivities were sustained in the CA1 pyramidal neurons after transient global cerebral ischemia.However,OJE pretreatment did not increase interleukin-2 and tumor necrosis factor-alpha immunoreactivities in the CA1 pyramidal neurons.Our findings suggest that pretreatment with OJE can protect neurons and attenuate gliosis from transient global cerebral ischemia via increasing expressions of interleukin-4 and-13.The experimental plan of this study was reviewed and approved by the Institutional Animal Care and Use Committee(IACUC)in Kangwon National University(approval No.KW-160802-1)on August 10,2016. | Joon Ha Park In Hye Kim Ji Hyeon Ahn YooHun Noh Sung-Su Kim Tae-Kyeong Lee Jae-Chul Lee Bich-Na Shin Tae Heung Sim Hyun Sam Lee Jeong Hwi Cho In Koo Hwang Il Jun Kang Jong Dai Kim Moo-Ho Won | 2019 | Neural Regeneration Research2019，14，9： | 6 |
| 2 | Efficacy and cost analysis of transrectal ultrasound-guided prostate biopsy under monitored anesthesia显示文摘镇静可以在指导的 transrectal 超声(TRUS ) 期间疼痛地导致减小前列腺活体检视。我们试图在在护理费用的指导 TRUS 的前列腺活体检视和相关增加期间评估 propofol 和 remifentanil 注入的联合的功效和安全。从 1 月到 2010 年 9 月,经历 transrectal 前列腺活体检视的 100 个人被使随机化进二个组。在组 1, 50 个病人收到了 propofol 和 remifentanil 的联合注入;在组 2, 50 个病人收到了 lidocaine 果冻。在指导 TRUS 的活体检视被执行以后,疼痛和耐心的满足被一个 10 点评估视觉模拟规模(管) ,和一张费用相关的耐心的满足问询表被所有病人完成。病人们也被问他们是否将愿意由一样的方法经历重复活体检视。在 1 看了显著地更低的管的组的病人在组 2 比那些得分(吝啬的管分数:0.9 ± 1.1 对 6.3 ± 2.5;P< 0.001 ) 。另外,耐心的满足规模在组 1 是显著地更高的(P=0.002 ) 。尽管全面费用在组 1 是显著地更高的(P=0.006 ) ,就费用而言的耐心的满足规模在这个组(P=0.009 ) 也是更高的。propofol 和 remifentanil 的联合在指导 TRUS 的前列腺活体检视期间是到减少病人疼痛和增加病人满足的一条安全、有效的路。尽管费用在收到了镇静,期望的组是更高的,病人展出了提高的满足和心甘情愿由一样的方法重复活体检视。 | Sung Gu Kang Bum Sik Tae Sam Hong Min Young Hwii Ko Seok Ho Kang Jeong Gu Lee Je Jong Kim Jun Cheon | 2011 | Asian Journal of Andrology2011，13，5： | 5 |
| 3 | EMR for early gastric cancer in Korea: a multicenter retrospective study显示文摘 | Jae J. Kim Jun Haeng Lee Hwoon-Yong Jung Gin Hyug Lee Joo Yong Cho Chang Beom Ryu Hoon Jai Chun Jong Jae Park Wan Sik Lee Hyun Soo Kim Moon Gi Chung Jeong Seop Moon Seok Reyol Choi Geun Am Song Hyun Yong Jeong Sam Ryong Jee Sang Yong Seol Yong Bum Yoon | 2007 | Gastrointestinal Endoscopy2007，，4： | 2 |
| 4 | Preparation and properties of water-borne polyurethanes显示文摘 | SANG YUP LEE JEONG SAM LEE BYUNG KYU KIM | 1997 | Polymer International1997，42，1： | 1 |
| 5 | Preparation and Properties of Water-Borne Polyurethanes显示文摘 | Sang Yup Lee Jeong Sam Lee Byung Kyu Kim | 1997 | Polymer International1997，42，1： | 1 |
| 6 | EMR for early gastric cancer in Korea: a multicenter retrospective study显示文摘 | Jae J. Kim Jun Haeng Lee Hwoon-Yong Jung Gin Hyug Lee Joo Yong Cho Chang Beom Ryu Hoon Jai Chun Jong Jae Park Wan Sik Lee Hyun Soo Kim Moon Gi Chung Jeong Seop Moon Seok Reyol Choi Geun Am Song Hyun Yong Jeong Sam Ryong Jee Sang Yong Seol Yong Bum Yoon | 2007 | Gastrointestinal Endoscopy2007，，4： | 1 |
| 7 | Modification of aqueous polyurethanes via latex ABCrosslinked polymers显示文摘 | Lee Jeong Sam Kim Byung Kyu | 2001 | Journal of Applied Polymer Science2001，82，： | 1 |
| 8 | Endoscopic resection for duodenal carcinoid tumors: A multicenter, retrospective study显示文摘 | Gwang Ha Kim Jin Il Kim Seong Woo Jeon Jeong Seop Moon Il‐Kwun Chung Sam‐Ryong Jee Heung Up Kim Geom Seog Seo Gwang Ho Baik Yong Chan Lee | 2014 | J Gastroenterol Hepatol2014，，2： | 1 |
| 9 | EMR for early gastric cancer in Korea: a multicenter retrospective study显示文摘 | Jae J. Kim Jun Haeng Lee Hwoon-Yong Jung Gin Hyug Lee Joo Yong Cho Chang Beom Ryu Hoon Jai Chun Jong Jae Park Wan Sik Lee Hyun Soo Kim Moon Gi Chung Jeong Seop Moon Seok Reyol Choi Geun Am Song Hyun Yong Jeong Sam Ryong Jee Sang Yong Seol Yong Bum Yoon | 2007 | Gastrointestinal Endoscopy2007，，4： | 1 |
| 10 | Anti-inflammatory effects of glycyrol isolated from Glycyrrhiza uralensis in LPS-stimulated RAW264.7 macrophages显示文摘 | Eun Myoung Shin Hong Yu Zhou Lian Yu Guo Jeong Ah Kim Seung Ho Lee Irmgard Merfort Sam Sik Kang Hak Sung Kim Sanghee Kim Yeong Shik Kim | 2008 | International Immunopharmacology2008，，11： | 1 |
| 11 | Effect of music on colonoscopy performance: A propensity scorematched analysis显示文摘BACKGROUND Music has been used to reduce stress and improve task performance during medical therapy.AIM To assess the effects of music on colonoscopy performance outcomes.METHODS We retrospectively reviewed patients who underwent colonoscopy performed by four endoscopists with popular music.Colonoscopy performance outcomes,such as insertion time,adenoma detection rate(ADR),and polyp detection rate(PDR),were compared between the music and non-music groups.To reduce selection bias,propensity score matching was used.RESULTS After one-to-one propensity score matching,169 colonoscopies were selected from each group.No significant differences in insertion time(4.97 vs 5.17 min,P=0.795)and ADR(39.1%vs 46.2%,P=0.226)were found between the two groups.Subgroup analysis showed that the insertion time(3.6 vs 3.8 min,P=0.852)and ADR(51.1%vs 44.7%,P=0.488)did not significantly differ between the two groups in experts.However,in trainees,PDR(46.9%vs 66.7%,P=0.016)and ADR(25.9%vs 47.6%,P=0.006)were significantly lower in the music than in the nonmusic group.CONCLUSION The current study found that listening to music during colonoscopy did not affect procedure performance.Moreover,it suggested that music may distract trainees from appropriately detecting adenomas and polyps. | Eun Jeong Choi Sam Ryong Jee Sang Heon Lee Jun Sik Yoon Seung Jung Yu Jong Hyun Lee Han Byul Lee Sang Wook Yi Myeong Pyo Kim Byung Cheol Chung Hong Sub Lee | 2023 | World Journal of Gastrointestinal Endoscopy2023，15，5： | 0 |
| 12 | 日韩之间不寻常的日常化学品显示文摘把它们看作有大规模破坏力的武器吧。对于智能手机和半导体的全球供应链至关重要的三种材料被卷入日本和韩国之间的外交争执中。这场争执的起源可追溯到两国变成消费电子巨头之前很早的时间。2019年7月,日本当局开始要求日本企业事先获取许可证,才能向韩国客户出口氟化聚酰亚胺、氟化氢和光刻胶。 | Min Jeong Lee Heejin Kim Sam Kim Pavel Alpeyev 竹西(译) | 2020 | 商业周刊(中文版)2020，0，5： | 0 |
| 13 | 基于辣椒基因组测序探究辣味在种群中的进化显示文摘辣椒(Capsicum annuum)是美洲最古老的驯化作物之一,在全世界被广泛种植。本研究对CM334(墨西哥地方品种)进行了全基因组测序和组装(覆盖度为186.6×),同时还对另外两个栽培种和一个野生种分别进行了重测序和从头(de novo)测序。结果表明辣椒基因组大小约为番茄的4倍,辣椒基因组上存在大量gypsy转座子和花椰菜病毒家族元件的积累。结合转录组综合分析认为,辣椒素合成酶基因表达模式的改变及新功能化是导致辣椒素生物合成的原因,研究还发现辣椒与番茄在乙烯合成及果实成熟调控方面存在明显不同的分子模式。辣椒参考基因组的发布为辣椒营养品质和药用价值的改善提供了重要平台。 | Seungill Kim Minkyu Park Seon-In Yeom Yong-Min Kim Je Min Lee Hyun-Ah Lee Eunyoung Seo Jaeyoung Choi Kyeongchae Cheong Ki-Tae Kim Kyongyong Jung Gir-Won Lee Sang-Keun Oh Chungyun Bae Saet-Byul Kim Hye-Young Lee Shin-Young Kim Myung-Shin Kim Byoung-Cheorl Kang Yeong Deuk Jo Hee-Bum Yang Hee-Jin Jeong Won-Hee Kang Jin-Kyung Kwon Chanseok Shin Jae Yun Lim June Hyun Park Jin Hoe Huh June-Sik Kim Byung-Dong Kim Oded Cohen Ilan Paran Mi Chung Suh Saet Buyl Lee Yeon-Ki Kim Younhee Shin Seung-Jae Noh Junhyung Park Young Sam Seo Suk-Yoon Kwon Hyun A Kim Jeong Mee Park Hyun-Jin Kim Sang-Bong Choi Paul W Bosland Gregory Reeves Sung-Hwan Jo Bong-Woo Lee Hyung-Taeg Cho Hee-Seung Choi Min-Soo Lee Yeisoo Yu Yang Do Choi Beom-Seok Park Allen van Deynze Hamid Ashrafi Theresa Hill Woo Taek Kim Hyun-Sook Pai Hee Kyung Ahn Inhwa Yeam James J Giovannoni Jocelyn K C Rose Iben Sφrensen Sang-Jik Lee Ryan W Kim Ik-Young Choi Beom-Soon Choi Jong-Sung Lim Yong-Hwan Lee Doil Choi 刘峰 张西露 | 2014 | 辣椒杂志2014，0，2： | 0 |
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