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| 1 | 克罗恩病:CT小肠成像、MR小肠成像和小肠灌肠造影的比较显示文摘目的前瞻性比较CT和MR小肠成像及小肠灌肠造影3种检查方法发现克罗恩病病人活动性小肠炎症和肠外并发症的准确性。方法机构伦理审查委员会批准本研究计划,并所有参与者知情同意。对连续31例克罗恩病或疑有克罗恩病的病人行CT和MR小肠成像、小肠灌肠造影和回肠结肠镜检查。2位独立的阅片者回顾CT和MR小肠成像及小肠灌肠造影影像以确定活动性末端回肠炎和肠道外并发症的存在。以回结肠镜检查结果作为参考标准,利用受试者工作特性曲线方法来评估CT和MR小肠成像及小肠灌肠造影确定活动性末端回肠炎的准确度。 | S.S. Lee A.Y. Kim S.K. Yang J. W. Chung S.Y. Kim S.H. Park 孙东辉(译) 万业达(校) | 2009 | 国际医学放射学杂志2009，32，4： | 57 |
| 2 | Calcineurin-B-Like Protein CBL9 Interacts with Target Kinase CIPK3 in the Regulation of ABA Response in Seed Germination显示文摘钙在植物在许多发信号的小径作为第二个送信人起一个重要作用。calcineurin 象 B 一样蛋白质(CBL ) 代表在钙由与他们的交往的蛋白质 kinases (CIPK ) 交往发信号工作的植物钙绑定蛋白质的一个家庭。在我们的以前的学习,我们在骆驼毛的织物发信号为 CBL (CBL9 ) 之一和 CIPK (CIPK3 ) 之一报导了一个角色。这里,我们证明了 CBL9 和 CIPK3 身体上并且机能上地在调整骆驼毛的织物回答与对方一起交往。CBL9 和 CIPK3 蛋白质在酵母与对方一起交往了二混血儿的系统并且当在植物房间表示了时。双变异的 cbl9cipk3 显示出类似的过分敏感的反应到在单个异种(cbl9 或 cipk3 ) 观察了的骆驼毛的织物。CIPK3 的组成地活跃的形式遗传上补充了 cbl9 异种,显示 CIPK3 CBL9 下游地工作。把调查结果基于这些,我们为调整骆驼毛的织物回答在一样的小径一起结束那 CBL9 和 CIPK3 幕。 | Girdhar K. Pandey John J. Grant Yong Hwa Cheong Beom-Gi Kim Le Gong Li Sheng Luan | 2008 | Molecular Plant2008，1，2： | 44 |
| 3 | 卒中后疲劳:新出现的证据与管理方法美国心脏协会对医疗卫生专业人员发布的科学声明显示文摘至少半数卒中存活者会经历疲劳;因此,卒中后疲劳是引起患者、看护者和临床医生顾虑的一个常见原因。本科学声明根据围绕卒中后疲劳的发病率、患病率、生活质量和复杂发病机制新出现的证据提供了国际性观点。文章对药物和非药物治疗干预的证据,以及卒中后疲劳对卒中存活者和看护者的影响进行了回顾。 | Janice L. Hinkle Kyra J. Becker Jong S. Kim Smi Choi-Kwon Karen L. Saban Norma McNair Gillian E. Mead 李力 王惠娟 苗江永 祝春华 陈荣 徐珊 张祥建 | 2017 | 国际脑血管病杂志2017，25，10： | 24 |
| 4 | 利用直接激发Rayleigh表面波的方法测量材料的声学非线性系数显示文摘提出了利用直接激发Rayleigh表面波的方法测量材料的声学非线性系数。采用专门的信号源,将压电传感器安装在试件边缘直接激发Rayleigh表面波,利用激光干涉仪测量系统采集试件表面的Rayleigh波信号。对采集到的Rayleigh波信号进行FFT变换,得到Rayleigh波信号中所包含的基频和高频成分,并据此进一步确定材料的声学非线性系数。对铝合金材料AA2024和AA6061的试验测量与分析结果表明,这种利用将压电传感器直接安装在试件边缘激发Rayleigh表面波的方法能够有效、准确地测量材料的声学非线性系数,可以为材料和结构早期力学性能退化的无损检测和评价提供一种有效的途径。 | 税国双 汪越胜 Jianmin Qu Jin-Yeon Kim Laurence J. Jacobs | 2008 | 声学学报2008，33，4： | 18 |
| 5 | Endoscopic treatment for early gastric cancer显示文摘Gastric cancer remains one of the most common causes of cancer death.However the proportion of early gastric cancer(EGC)at diagnosis is increasing.Endoscopic treatment for EGC is actively performed worldwide in cases meeting specific criteria.Endoscopic mucosal resection can treat EGC with comparable results to surgery for selected cases.Endoscopic submucosal dissection(ESD)increases the en bloc and complete resection rates and reduces the local recurrence rate.ESD has been performed with expanded indication and is expected to be more widely used in the treatment of EGC through the technological advances in the near future.This review will describe the techniques,indications and outcomes of endoscopic treatment for EGC. | Yang Won Min Byung-Hoon Min Jun Haeng Lee Jae J. Kim | 2014 | World Journal of Gastroenterology2014，20，16： | 18 |
| 6 | Tooth regeneration: a revolution in stomatology and evolution in regenerative medicine显示文摘A tooth is a complex biological organ and consists of multiple tissues including the enamel, dentin, cementum and pulp. Tooth loss is the most common organ failure. Can a tooth be regenerated? Can adult stem cells be orchestrated to regenerate tooth structures such as the enamel, dentin, cementum and dental pulp, or even an entire tooth? If not, what are the therapeutically viable sources of stem cells for tooth regeneration? Do stem cells necessarily need to be taken out of the body, and manipulated ex vivo before they are transplanted for tooth regeneration? How can regenerated teeth be economically competitive with dental implants? Would it be possible to make regenerated teeth affordable by a large segment of the population worldwide? This review article explores existing and visionary approaches that address some of the above-mentioned questions. Tooth regeneration represents a revolution in stomatology as a shift in the paradigm from repair to regeneration: repair is by metal or artificial materials whereas regeneration is by biological restoration. Tooth regeneration is an extension of the concepts in the broad field of regenerative medicine to restore a tissue defect to its original form and function by biological substitutes. | Sibel Yildirim Susan Y. Fu Keith Kim Hong Zhou Chang Hun Lee Ang Li Sahng Gyoon Kim Shuang Wang Jeremy J. Mao | 2011 | International Journal of Oral Science2011，3，3： | 16 |
| 7 | Burden of Gastrointestinal Disease in the United States: 2012 Update显示文摘 | Anne F. Peery Evan S. Dellon Jennifer Lund Seth D. Crockett Christopher E. McGowan William J. Bulsiewicz Lisa M. Gangarosa Michelle T. Thiny Karyn Stizenberg Douglas R. Morgan Yehuda Ringel Hannah P. Kim Marco Dacosta DiBonaventura Charlotte F. Carroll Je | 2012 | Gastroenterology2012，，5： | 15 |
| 8 | Overexpression of Arabidopsis YUCCA6 in Potato Results in High-Auxin Developmental Phenotypes and Enhanced Resistance to Water Deficit显示文摘Indole-3-acetic 酸(IAA ) ,主要植物植物生长素,在色氨酸依赖者和色氨酸无关的小径被生产。在 Arabidopsis thaliana 的一条主要小径从色氨酸在二反应产生 IAA。步骤一由把国际语音学协会变换成丝兰属植物蛋白质催化的 IAA 的一个限制率的步骤跟随的色氨酸 aminotransferases 把色氨酸变换成 indole-3-pyruvic 酸(国际语音学协会) 。我们识别了推出了氨基酸序列的基因分享的八通常认为的 StYUC (茄属 tuberosum 丝兰属植物) Arabidopsis 丝兰属植物蛋白质的有那些的 50%70% 身份。都包括正规、保存丝兰属植物序列:FATGY 主题, FMO 签名顺序和 NADP 有约束力的序列。另外,五基因与 ~ 被发现 50% 氨基酸顺序身份到 Arabidopsis 色氨酸 aminotransferases。转基因的土豆(茄属 tuberosum cv。Jowon ) 组成地, overexpressing Arabidopsis AtYUC6 显示了象狭窄的向下卷的叶子,增加的高度,直立的身高,和长寿那样的高植物生长素的显型。转基因的土豆植物 overexpressing AtYUC6 基于减少的水损失显示出提高的干旱忍耐。显型在叶子与反应的氧种类的减少的层次被相关。结果在可以被利用改变植物回答到环境的土豆建议植物生长素生合成的一条功能的丝兰属植物小径。 | Jeong Im Kim Dongwon Baek Hyeong Cheol Park Hyun Jin Chun Dong-Ha Oh Min Kyung Lee Joon-Yung Cha Woe-Yeon Kim Min Chul Kim Woo Sik Chung Hans J. Bohner Sang Yeol Lee Ray A. Bressan Shin-Woo Lee Dae-Jin Yun | 2013 | Molecular Plant2013，6，2： | 15 |
| 9 | Small RNA Profiling Reveals Phosphorus Deficiency as a Contributing Factor in Symptom Expression for Citrus Huanglongbing Disease显示文摘Huanglongbing (HLB ) 是与类 Candidatus Liberibacter 的细菌被联系的破坏柠檬疾病(Ca。L.) 。强大的诊断工具和管理策略被需要控制 HLB。小 RNA (sRNA ) 玩的主人在调整主人回答到病原体感染的一个重要角色并且为许多人的疾病被用作早诊断的标记,包括癌症。决定是否柠檬 sRNAs 调整主人回答到 HLB, sRNAs 从柠檬 sinensis 被介绍有 Ca 的 10 和 14 星期柱子 grafting。L。asiaticus (Las ) 积极或健康的织物。十新 microRNAs (miRNAs ) , 76 保存 miRNAs,和许多小介入 RNA (siRNAs ) 被发现。几 miRNAs 和 siRNAs 被 Las 感染高度导致,并且能潜在地被开发进 HLB 的早诊断标记。miR399,被磷饥饿在另外的植物种类导致,被与类似于 HLB 的症状引起柠檬 stubborna 疾病的 Las 然而并非 Spiroplasma citri 的感染明确地导致。我们与健康的树相比在 Las 积极的柠檬树上发现了磷的 35% 减小。HLB 积极的香甜的橘子树的适用的磷 oxyanion 答案减少了 HLB 症状严厉并且显著地在西南佛罗里达在 3 年的地试用期间改进了水果生产。我们的分子,生理,并且地数据建议那磷缺乏被连接到 HLB 疾病 symptomology。 | Hongwei Zhao Ruobai Sun Ute Albrecht Chellappan Padmanabhan Airong Wanga Michael D. Coffey Thomas Girke Zonghua Wang Timothy J. Close Mikeal Roose Raymond K. Yokomi Svetlana Folimonova Georgios Vidalakis Robert Rouse Kim D. Bowman Hailing Jin | 2013 | Molecular Plant2013，6，2： | 12 |
| 10 | The adult human testis transcriptional cell atlas显示文摘Human adult spermatogenesis balances spermatogonial stem cell (SSC) self-renewal and differentiation,alongside complex germ cell-niche interactions,to ensure long-term fertility and faithful genome propagation. Here,we performed single-cell RNA sequencing of -6500 testicular cells from young adults. We found five niche/somatic cell types (Leydig,myoid,Sertoli,endothelial,macrophage),and observed germline-niche interactions and key human-mouse differences. Spermatogenesis,including meiosis,was reconstructed computationally,revealing sequential coding,non-coding,and repeat-element transcriptional signatures. Interestingly,we identified five discrete transcriptional/developmental spermatogonial states,including a novel early SSC state,termed State 0. Epigenetic features and nascent transcription analyses suggested developmental plasticity within spermatogonial States. To understand the or丨gin of State 0,we profiled testicular cells from infants,and identified distinct similarities between adult State 0 and infant SSCs. Overall,our datasets describe key transcriptional and epigenetic signatures of the normal adult human testis,and provide new insights into germ cell developmental transitions and plasticity. | Jingtao Guo Edward J. Grow Hana Mlcochova Geoffrey J. Maher Cecilia Lindskog Xichen Nie Yixuan Guo Yodai Takei Jina Yun Long Cai Robin Kim Douglas T. Carrell Anne Goriely James M. Hotaling Bradley R. Cairns | 2018 | Cell Research2018，28，12： | 12 |
| 11 | 光敏灭菌辅助龈下刮治后不同深度牙周袋的恢复率比较研究显示文摘目的评价PERIOWAVETM光敏灭菌法治疗慢性牙周炎后≥4mm牙周袋的恢复效果。方法经伦理委员会同意后,选择45例患者(每位患者口腔内至少有4个以上≥5mm的牙周袋并分布在2个以上口腔区域内),在接受基础检查以及根面平整术(SRP)治疗后,随机分入3组,A组在SRP之后接受1次PERIOWAVETM光敏灭菌治疗,B组在SRP后及6周后各接受1次PERIOWAVETM治疗,而C组仅接受SRP治疗。在基础检查及12周后测量牙周袋深度。结果在基础检查中共有1851个≥5mm牙周袋,经过治疗后,C组有212(36.7%)个牙周袋≤3mm,A组有160(62.5%)个牙周袋≤3mm,而B组有187(84.6%)个牙周袋≤3mm;705个4mm的牙周袋,治疗后PD≤3mm的C组147(66.5%)个,A组160(62.5%)个,B组187(84.6%)个。经两样本二项分布检验,对于基础检查中为测量为4mm及≥5mm牙周袋,B组的恢复均明显好于A组及C组(P<0.0001)。结论在SRP基础上加以2次光敏灭菌治疗牙周炎对于浅(4mm)及深(≥5mm)牙周袋深度的恢复均明显大于单独使用SRP。 | 王莹 朱形好 林芝 张秀华 陈宏 丁熙 王靖虓 李一鸣 S. LEE J. KIM 邓辉 | 2008 | 口腔医学2008，28，6： | 11 |
| 12 | Experimental and Numerical Investigation on Impact Performance of Carbon Reinforced Aluminum Laminates显示文摘It is known that fiber metal laminates (FML) as one of hybrid materials with thin metal sheets and fiber/epoxy layers have the characteristics of the excellent damage tolerance, fatigue and impact properties with a relatively low density. Therefore, the mechanical components using FML can contribute the enhanced safety level of the sound construction toward the whole body. In this study, the impact performance of carbon reinforced aluminum laminates (CARAL) is investigated by experiments and numerical simulations. Drop weight tests are carried out with the weight of 4.7 kg at the speed of 1 and 2 m/s, respectively. Dynamic non-linear transient analyses are also accomplished using a finite element analysis software, ABAQUS. The experiment results and numerical results are compared with impact load-time histories. Also, energy-time histories are applied to investigate the impact performance of CARAL. | S.H. Song Y.S. Byun T.W. Ku W.J. Song J. Kim B.S. Kang | 2010 | Journal of Materials Science & Technology2010，26，4： | 10 |
| 13 | Ultrahigh electron mobility in suspended graphene显示文摘 | K.I. Bolotin K.J. Sikes Z. Jiang M. Klima G. Fudenberg J. Hone P. Kim H.L. Stormer | 2008 | Solid State Communications2008，，9： | 6 |
| 14 | Mass Spectrometric Analyses Reveal a Central Role for Ubiquitylation in Remodeling the Arabidopsis Proteome during Photomorphogenesis显示文摘 | Victor Aguilar-Hernandez Do-Young Kim Robert J. Stankey Mark Scalf Lloyd M. Smith Richard D. Vierstra | 2017 | Molecular Plant2017，10，6： | 6 |
| 15 | Endoscopic submucosal dissection with sentinel node navigation surgery for early gastric cancer显示文摘 | G. Bok Y. Kim S. Jin C. Chun T. Lee H. Kim S. Jeon J. Cho | 2012 | Endoscopy2012，，10： | 5 |
| 16 | Endocrine Regulation of Energy Metabolism by the Skeleton显示文摘 | Na Kyung Lee Hideaki Sowa Eiichi Hinoi Mathieu Ferron Jong Deok Ahn Cyrille Confavreux Romain Dacquin Patrick J. Mee Marc D. McKee Dae Young Jung Zhiyou Zhang Jason K. Kim Franck Mauvais-Jarvis Patricia Ducy Gerard Karsenty | 2007 | Cell2007，，3： | 5 |
| 17 | 肝脏恶性肿瘤经导管动脉化疗性栓塞术后-过性肝脏密度差异(THAD)系列CT检查的变化显示文摘本研究的目的是研究经导管动脉化疗栓塞术(TACE)引起的一过性肝脏密度差异(THAD)的自然病程变化。对32个月内32例经导管动脉化疗栓塞术治疗后的肝细胞癌病人在系列CT检查中发现的40处THAD进行了回顾性分析。THAD定义为肝脏cT动态扫描(横断位,层厚1.9-8.8cm,平均4.9cm)肝动脉期在碘油堆积灶旁出现的局灶性、一过性、周围肝实质的强化。40处由TACE引发的THAD中,18处(45%)伴有动脉-门静脉瘘(APF),9处(23%)伴有门静脉狭窄(PVS),此外, | S.H. Hwang J.S. Yu J. Chung J.J. Chung J.H .Kim K.W. Kim 叶锦棠(译) 唐光健(校) | 2008 | 国际医学放射学杂志2008，31，5： | 4 |
| 18 | International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma显示文摘 | William D. Travis Elisabeth Brambilla Masayuki Noguchi Andrew G. Nicholson Kim R. Geisinger Yasushi Yatabe David G. Beer Charles A. Powell Gregory J. Riely Paul E. Van Schil Kavita Garg John H. M. Austin Hisao Asamura Valerie W. Rusch Fred R. Hirsch Giorg | 2011 | Journal of Thoracic Oncology2011，，2： | 4 |
| 19 | Combinations of eight key mutations in the X /pre C region and genomic activity of hepatitis B virus are associated with hepatocellular carcinoma显示文摘 | Y. M. Park J. W. Jang S. H. Yoo S. H. Kim I. M. Oh S. J. Park Y. S. Jang S. J. Lee | 2014 | J Viral Hepat2014，，3： | 4 |
| 20 | Precipitate Contribution to the Acoustic Nonlinearity in Nickel-Based Superalloy显示文摘 | Chung-Seok KIM Cliff J. LISSENDEN | 2009 | Chinese Physics Letters2009，26，8： | 4 |
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