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| 1 | Radiation-induced sarcomas of the head and neck显示文摘With improved outcomes associated with radiotherapy, radiation-induced sarcomas(RIS) are increasingly seen in long-term survivors of head and neck cancers, with an estimated risk of up to 0.3%. They exhibit no subsite predilection within the head and neck and can arise in any irradiated tissue of mesenchymal origin. Common histologic subtypes of RIS parallel their de novo counterparts and include osteosarcoma, chondrosarcoma, malignant fibrous histiocytoma/sarcoma nitricoxide synthase, and fibrosarcoma. While imaging features of RIS are not pathognomonic, large size, extensive local invasion with bony destruction, marked enhancement within a prior radiotherapy field, and an appropriate latency period are suggestive of a diagnosis of RIS. RIS development may be influenced by factors such as radiation dose, age at initial exposure, exposure to chemotherapeutic agents and genetic tendency. Precise pathogenetic mechanisms of RIS are poorly understood and both directly mutagenizing effects of radiotherapy as well as changes in microenvironments are thought to play a role. Management of RIS is challenging, entailing surgery in irradiated tissue and a limited scope for further radiotherapy and chemotherapy. RIS is associated with significantly poorer outcomes than stagematched sarcomas that arise independent of irradiationand surgical resection with clear margins seems to offer the best chance for cure. | Anuradha Thiagarajan N Gopalakrishna Iyer | 2014 | World Journal of Clinical Oncology2014，5，5： | 5 |
| 2 | Routers with a single stage of buffering 显示文摘 | Iyer S Zhang Rui McKeown N | 2002 | ACM SIGCOMM Computer Communication Review2002，35，： | 1 |
| 3 | Noninvasive imaging of cationic lipid-mediated delivery of optical and PET reporter genes in living mice显示文摘 | IYER M BERENJI M TEMPLETON N | 2002 | Molecular Therapy2002，6，： | 1 |
| 4 | Contribution of angiotensin-(1-7) to blood pressure regulation in salt-depleted hypertensive rats显示文摘 | IYER S N AVERILL D B CHAPPELL M C | 2000 | Hypertension2000，36，3： | 1 |
| 5 | A Family of Dominance Rules for Multiattribute Decision Making under Uncertainty显示文摘 | Iyer N S | 2003 | IEEE Trans on Systems Man and Cybernetics-Part A:Systems and Humans2003，33，4： | 1 |
| 6 | Change in blood pressure after treatment of patent ductus arteriosus with indomethacin显示文摘 | Evans N Iyer P | 1993 | Arch Dis Child1993，68，5： | 1 |
| 7 | Controversies in themultimodality management of locally advanced esophageal canc-er: evidence-based review of surgery alone and combined-modali-ty therapy 显示文摘 | IYER R WILKINSON N’DEMMY T | 2004 | Ann Surg Oncol2004，11，7： | 1 |
| 8 | Three-dimensional shape searching: state-of-the-art review and future trends 显示文摘 | IYER N JAYANTI S LOU Kui-yang | 2005 | ComputerAided Design2005，37，5： | 1 |
| 9 | Developing an engineering shape benchmark for CAD models显示文摘 | JAYANTI S KALYANARAMAN Y IYER N | 2006 | Computer-Aided Design2006，38，9： | 1 |
| 10 | Knock- down of CDK2AP1 in primary human fibroblasts induces p53 dependent senescence显示文摘 | ALSAYEGH K N GADEPALLI V S IYER S | 2015 | PLoS One2015，10，01： | 1 |
| 11 | Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1显示文摘 | Forsythe J A Jiang B H Iyer N V | 1996 | Mol Cell Biol1996，16，： | 1 |
| 12 | Developing an engineering shape benchmark for CAD models显示文摘 | JAYANTI S KALYANARAMAN Y IYER N | 2006 | Computer-Aided Design2006，38，9： | 1 |
| 13 | The use of streaming potential measurements to study the fouling and cleaning of ultrafiltration membranes 显示文摘 | LAWRENCE N D PERERA J M IYER M | 2006 | Separation and Purification Technology2006，48，2： | 1 |
| 14 | Variable structure slewing control and vibration damping of flexible spacecraft显示文摘 | Iyer A Singh S N | 1991 | Acta Astronautica1991，25，1： | 1 |
| 15 | Developing an engineering shape benchmark for cad models显示文摘 | JAYANTI S KALYANARAMAN Y IYER N | 2006 | Computer-Aided Design2006，38，9： | 1 |
| 16 | Incompetence of the foramen ovale in preterm infants requiring ventilation 显示文摘 | EVANS N IYER P | 1994 | J Pediatr1994，125，4： | 1 |
| 17 | Solvent Extraction and Separation Studies of Antimony( m )and Bismuth( Ⅲ )by Using Cya nex 925显示文摘 | Iyer J N Dhadke P M | 2003 | Ind J Chem Technol2003，，： | 1 |
| 18 | Variable structure slewing control and vibration damping of flexible spacecraft显示文摘 | Iyer A Singh S N | 1991 | Acta Astronautica1991，25，1： | 1 |
| 19 | Commitment, coordination, competence and the iron triangle 显示文摘 | Jha K N K C Iyer | 2007 | International Journal of Project Management2007，25，5： | 1 |
| 20 | Solvent extraction and separation studies of Antimony(Ⅲ)and Bismuth(Ⅲ)by using cyanex-925显示文摘 | Iyer J N Dhadke P M | 2003 | Ind J Chem Technol2003，，10： | 1 |
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