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| 1 | Cycling of antibiotics for the prophylaxis of recurrent spontaneous bacterial peritonitis in a cirrhotic patient显示文摘TO THE EDITOR
More than 80% of cirrhotic patients who have been treated successfully for spontaneous bacterial peritonitis (SBP)experience a recurrence[1,2]. Long-term prophylaxis with single daily oral antibiotic has been shown to be cost effective in delaying a recurrence but only for a short time[3].What has never been tested in this population is the cycling of antibiotics. We report the beneficial use of antibiotic cycling for 36 weeks in a 74-year-old woman with cryptogenic cirrhosis and recurrent SBP. | N Assy S Schlesinger D Miron O Hussein | 2005 | World Journal of Gastroenterology2005,11,41: | 3 |
| 2 | Association between thrombotic risk factors and extent of fibrosis in patients with non-alcoholic fatty liver diseases显示文摘AIM: To evaluate the prevalence of genetic and acquired prothrombotic risk factors and their association with the extent of fibrosis and fatty infiltration in patients with non-alcoholic fatty liver disease (NAFLD).METHODS: Forty-four patients with chronic hepatitis (28 men and 16 women, with mean age of 45±11 and 49±12 years, respectively) constituted the patient population of this study. The groups were divided as follows: 15 patients with fatty liver (FL); 15 with non-alcoholic steatohepatitis (NASH); 14 with chronic viral hepatitis (CH) diagnosed by histology and liver technetium scan or ultrasound; and 10 healthy individuals. Thrombophilic, coagulation factors and genetic mutations were diagnosed by standard hemostatic and molecular coagulation assays.RESULTS: Activated protein C (APC) resistance and protein S were the most prevalent thrombotic risk factors (6% and 10% in NAFLD vs 21% and 14% in CH; P<0.01 and P<0.05, respectively). One thrombotic risk factor was identified in 41% of patients (23% mild fibrosis, 18% severe fibrosis) and two thrombotic risk factors in 6% of patients with NAFLD and severe fibrosis. While no differences in APC ratio, lupus anticoagulant, fibrinogen, factor V Leiden,prothrombin, and MTHFR mutation were found. Protein S levels were significantly lower in NASH patients than in patients with FL alone (92±19 vs106±2, P<0.01). Protein C levels were markedly higher in patients with NAFLD and mild or severe fibrosis as compared to the patients with CH, respectively (128±40 vs96±14, P<0.001 or 129±36 vs 88±13, P<0.01).CONCLUSION: Up to 46% of patients with NAFLD may have thrombotic risk factors, and the presence of thrombotic risk factors is correlated with the extent of hepatic fibrosis,suggesting a crucial role of the coagulation system in the pathogenesis of hepatic fibrosis. | N Assy I Bekirov Y Mejritsky L Solomon S Szvalb O Hussein | 2005 | World Journal of Gastroenterology2005,11,37: | 3 |
| 3 | Retrospective population pharma cokinetic analysis of cetirizine in children aged 6 months to 12 years显示文摘 | Pitsiu M Hussein Z Majid O | 2004 | Br J Glin Pharmacol2004,57,4: | 1 |
| 4 | Steep Dispersion and Group Velocity Below c/3000 in Coherent Population Trapping显示文摘 | SCHMIDT O WYNANDS R HUSSEIN Z | | 0,,: | 1 |
| 5 | Nematode acetylcholinesterases are encoded by multiple genes and perform non-overlapping functions显示文摘 | SELKIRK M E LAZARI O HUSSEIN A S | 2005 | Chem Biol Interact2005,,: | 1 |
| 6 | Serum CA125: a tumor marker for monitoring response to treatment and follow-up in patients with non-Hodgkin's lymphoma 显示文摘 | ZIDAN J HUSSEIN O BASHER W | 2004 | Oncologist2004,9,4: | 1 |
| 7 | Self-assembled Nanocomposite of Organic-inorganic Hybrid显示文摘 | Hussein M Z B Zainal Z Tat O W S | 2000 | Journal of Chemistry2000,16,2: | 1 |
| 8 | The effect of current mode and discharge type on the corrosion resistance of plasma electrolytic oxidation (PEO) coated magnesium alloy AJ62显示文摘 | Hussein R O Zhang P Nie X | 2011 | Surface and Coatings Technology2011,206,: | 1 |
| 9 | Video-assisted axillary surgery for cancer: non-randomized comparison with conventional techniques 显示文摘 | Hussein O EI-Nahhas W EI-Saed A el al | 2007 | Breast2007,16,5: | 1 |
| 10 | Serum CA125: a tumor marker for monitoring response to treatment and followup in patients with non-Hodgkin ' s lymphoma 显示文摘 | Zidan J Hussein O Basher W | 2004 | Oneologist2004,9,4: | 1 |
| 11 | Spectroscopic study of electrolytic plasma and discharging behaviour during the plasma electrolytic oxidation (PEO) process显示文摘 | R O Hussein X Nie D O Northwood A Yerokhin A Matthews | 2010 | Journal of Physics D: Applied Physics2010,,10: | 1 |
| 12 | Serum CA125 :a tumor marker for monitoring response to treatment and follow-up in patients with non-Hodgkin's lymphoma显示文摘 | Zidan J Hussein O Basher W | 2004 | Oncologist2004,9,: | 1 |
| 13 | Laser subepithelial keratomileusis for the correction of high myopia with the schwind esiris scanning spot laser 显示文摘 | O' Brart DPS Attar MA Hussein B | 2006 | J Refract Surg2006,22,: | 1 |
| 14 | Deaths in children during an outbreak of hand, foot, and mouth disease in Peninsular Malaysia--clin- ical and pathological characteristics 显示文摘 | Shekhar K Lye MS Norlijah O Ong F Looi LM Khuzai- ah R Marzuki I Hussein I Wong SL Mohan J Sinniah M Abu Bakar S | 2005 | Med J Malaysia2005,60,3: | 1 |
| 15 | Severe hepatotoxicity associated with the combination of spiramycin plus metronidazole显示文摘 | Hussein R El-Halabi M Ghaith O | 2011 | Arab J Gastroenterol2011,12,1: | 1 |
| 16 | Phytoremediation of Mercury and Organomercurials in Chloroplast Transgenic Plants: Enhanced Root Uptake, Translocation to Shoots, and Volatilization 显示文摘 | HUSSEIN H S RUIZ O N TERRY N | 2007 | Environmental Science and Technology2007,41,24: | 1 |
| 17 | Valsartan therapy has additive anti-oxidative effect to that of fluvastatin therapy against low-density lipoprotein oxidation:studies in hypercholesterolemic and hypertensive patients显示文摘 | Hussein O Shneider J Rosenblat M | 2002 | J Cardiovasc Pharmacol2002,40,: | 1 |
| 18 | Interactions of Platelets,Macrophages,and Lipoproteins in Hypercholesterolemia:Antiatherogenic Effects of HMGCoA Reductase Inhibitor Therapy显示文摘 | Aviram M Hussein O Rosenblat M | 1998 | J Cardiovasc Pharmacol1998,31,1: | 1 |
| 19 | An evaluation of the Sysmex NE-8000 hematology analyzer显示文摘 | Hallawell R O Malley C Hussein S | 1991 | Am J Clin Pathol1991,96,: | 1 |
| 20 | Arterial elasticity in obese subjects with coronary slow flow phenomenon显示文摘 | Hussein O Zidan J Plich M | 2013 | Isr Med Assoc J2013,15,12: | 1 |