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| 1 | Passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts and assessment of clinical outcomes显示文摘AIM To assess for passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts(TIPS) and compare outcomes with maximally dilated TIPS.METHODS Polytetrafluoroethylene covered TIPS(Viatorr) from July 2002 to December 2013 were retrospectively reviewed at two hospitals in a single institution. Two hundred and thirty patients had TIPS maximally dilated to 10 mm(m TIPS), while 43 patients who were at increased risk for hepatic encephalopathy(HE), based on clinical evaluation or low pre-TIPS portosystemic gradient(PSG), had 10 mm TIPS sub-maximally dilated to 8 mm(sm TIPS). Group characteristics(age, gender, Model for End-Stage Liver Disease score, post-TIPS PSG and clinical outcomes were compared between groups, including clinical success(ascites or varices), primary patency,primary assisted patency, and severe post-TIPS HE. A subset of fourteen patients with sm TIPS underwent follow-up computed tomography imaging after TIPS creation, and were grouped based on time of imaging(< 6 mo and > 6 mo). Change in diameter and crosssectional area were measured with 3D imaging software to evaluate for passive expansion.RESULTS Patient characteristics were similar between the sm TIPS and m TIPS groups, except for pre-TIPS portosystemic gradient, which was lower in the sm TIPS group(19.4 mm Hg ± 6.8 vs 22.4 mm Hg ± 7.1, P = 0.01). Primary patency and primary assisted patency between sm TIPS and m TIPS was not significantly different(P = 0.64 and 0.55, respectively). Four of the 55 patients(7%) with sm TIPS required TIPS reduction for severe refractory HE, while this occurred in 6 of the 218 patients(3%) with m TIPS(P = 0.12). For the 14 patients with follow-up computed tomography(CT) imaging, the median imaging follow-up was 373 d. There was an increase in median TIPS diameter, median percent diameter change, median area, and median percent area change in patients with CT follow-up greater than 6 mo after TIPS placement compared to follow-up within 6 mo(8.45 mm, 5.58%, 56.04 mm^2, and 11.48%, respectively, P = 0.01).CONCLUSION Passive expansion of sm TIPS does occur but clinical outcomes of sm TIPS and m TIPS were similar. Sub-maximal dilation can prevent complications related to overshunting in select patients. | Michael C Hsu Charles N Weber S William Stavropoulos Timothy W Clark Scott O Trerotola Richard D Shlansky Goldberg Michael C Soulen Gregory J Nadolski | 2017 | World Journal of Hepatology2017，9，12： | 11 |
| 2 | Genetic analysis of organ fusion in Arabidopsis thaliana显示文摘 | LOLLE S J HSU W PRUITT R E | 1998 | Genetics1998，149，2： | 1 |
| 3 | Characterizations and models for the thermal growth of a motorized high speed spindle 显示文摘 | Chen J S Hsu W Y | 2003 | International Journal of Machine Tools & Manufacture2003，，43： | 1 |
| 4 | Differentially transcribed genes in skeletal muscle of Duroc and Taoyuan pigs显示文摘 | Lin C S Hsu C W | 2005 | Journal of Animal Sci- ence2005，83，9： | 1 |
| 5 | Isolation and characterization of a cDNA encoding chalcone synthase homolog from Phalaenopsis显示文摘 | Hsu W S Do Y Y Huang P L | 1997 | Plant Physiol1997，113，： | 1 |
| 6 | Experience in the surgical management of spontaneous spinal epidural hematoma显示文摘 | LIAO C C LEE S T HSU W C | 2004 | J Neu- rosurg2004，100，1： | 1 |
| 7 | Cubic AgPb, SbTez+,, : bulk thermoelectric materials with high figure of merit 显示文摘 | Hsu K F Loo S Guo F Chen W Dyck J S Uher C Hogan T Polychroniadis E K Kanatzidis M G | 2004 | Science2004，303，： | 1 |
| 8 | CPW-fed slot-loop coupled patch antenna on narrow substrate 显示文摘 | LU S W HUANG T F HSU P | 1999 | Electron Lett1999，35，： | 1 |
| 9 | New bathymetry and magnetic lineations identifications in the northernmost South China Sea and their tectonic implications显示文摘 | Hsu S K Yeh Y Doo W B | 2004 | Marine Geophysical Research2004，25，1： | 1 |
| 10 | Mutations in the acetylcholinesterase gene of Bactrocera dorsalis associated with resistance to organophosphorus insecticides 显示文摘 | Hsu J C Haymerc D S Wu W J | 2006 | Insect Biochem Mol Biol2006，36，： | 1 |
| 11 | Ceramic wear maps:Zirconia显示文摘 | Lee S W Hsu S M Shen M C | 1993 | J Am Ceram Soc1993，76，8： | 1 |
| 12 | Novel epoxy/expandable graphite halo- gen-free flame retardant composites-preparation, characteriza- tion and properties显示文摘 | Chiang C L Hsu S W | 2010 | J Polym Res2010，17，： | 1 |
| 13 | A novel liquid thermal polymeriza- tion resist for nanoimprint lithography with low shrinkage and high flowability 显示文摘 | LIAO W C HSU S L C | 2007 | Nanoteehnology2007，18，6： | 1 |
| 14 | Structures,thermal stabilities,and magnetic properties of four new lanthanide coordinative frameworks incorporating mixed organic ligands显示文摘 | Jian B R Liu H C Lin Y W Huang S C Hsu K F | | 0，，1： | 1 |
| 15 | A computer-assisted colour selection system based on aesthetic measure for colour harmony and fuzzy logic theory显示文摘 | Hsiao S W Chiu F Y Hsu H Y | | 0，，05： | 1 |
| 16 | Variations of Cd/Pb and Zn/Pb ratios in Taipei aerosols reflecting long-range transport or local pollution emissions显示文摘 | Hsu S C Liu S C Jeng W L | 2005 | Science of the Total Environment2005，347，123： | 1 |
| 17 | WxMoyCzS2 nanotubes显示文摘 | Zhu Y Q Frith S | 2001 | Carbon2001，39，： | 1 |
| 18 | Surgical treat ment of endobronchial tuberculosis显示文摘 | HSU H S HSU W H HUANG H S | 1997 | Scand Cardiovasc J1997，31，1： | 1 |
| 19 | Antiplane diffraction from canyon above subsurface unlined tunner显示文摘 | LEE V W CHEN S HSU I R | 1999 | Eng Mech Div ASCE1999，125，2： | 1 |
| 20 | All solid-state electric double-layer capacitors based on alkaline polyvinyl alcohol polymer electrolytes显示文摘 | Yang C C Hsu S T Chen W C | 2005 | J Power Sources2005，152，： | 1 |
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