|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A comparison of the relative efficiency of ICSI and extended culture with epididymal sperm versus testicular sperm in patients with obstructive azoospermia显示文摘This is a retrospective cohort study comparing blastocyst transfer outcomes following intracytoplasmic sperm injection utilizing epididymal versus testicular sperm for men with obstructive azoospermia.All cases at a single center between 2012 and 2016 were included.Operative approach was selected at the surgeon’s discretion and included microepididymal sperm aspiration or testicular sperm extraction.Blastocyst culture was exclusively utilized prior to transfer.The primary outcome was live birth rate.Secondary outcomes included fertilization rate,blastulation rate,euploidy rate,and implantation rate.A mixed effects model was performed.Seventy-six microepididymal sperm aspiration cases and 93 testicular sperm extraction cases were analyzed.The live birth rate was equivalent(48.6%vs 50.5%,P=0.77).However,on mixed effects model,epididymal sperm resulted in a greater likelihood of fertilization(adjusted OR:1.37,95%CI:1.05–1.81,P=0.02)and produced a higher blastulation rate(adjusted OR:1.41,95%CI:1.1–1.85,P=0.01).As a result,the epididymal sperm group had more supernumerary blastocysts available(4.3 vs 3,P<0.05).The euploidy rate was no different.Pregnancy rates were no different through the first transfer cycle.However,intracytoplasmic sperm injection following microepididymal sperm aspiration resulted in a greater number of usable blastocysts per patient.Thus,the true benefit of epididymal sperm may only be demonstrated via a comparison of cumulative pregnancy rates after multiple transfers from one cohort. | Scott J Morin Brent M Hanson Caroline R Juneau Shelby A Neal Jessica N Landis Richard T Scott Jr James M Hotaling | 2020 | Asian Journal of Andrology2020，22，2： | 2 |
| 2 | Clinical genetic testing for male factor infertility: current applications and future directions 显示文摘 | Hotaling J Carrell DT | 2014 | Andrology2014，2，3： | 1 |
| 3 | Deep neck infections显示文摘 | Hotaling A J | 1996 | Am J Otolaryngol1996，17，5： | 1 |
| 4 | The Role of Tonsillectomy in Pediatric IgA Nephropathy 显示文摘 | Mariotti A J Agrawal R Hotaling AJ | 2009 | Arch Otolaryngol Head Neck Surg2009，135，1： | 1 |
| 5 | Effect of collecting duct histol- ogy on renal cell cancer outcbme 显示文摘 | Wright JL Risk MC Hotaling J | 2009 | J Urol2009，182，6： | 1 |
| 6 | Drooling 显示文摘 | Lal D Hotaling A J | 2006 | Curr Opin Otolaryngol Head Neck Surg2006，14，6： | 1 |
| 7 | Predictors of upper tract urothelial cell carcinoma after primary bladder cancer: a population based analysis显示文摘 | Wright JL Hotaling J Porter MP | 2009 | J Urol2009，181，3： | 1 |
| 8 | Predictors of upper tract urothelial cell carcinoma after primary bladder cancer:, a population based analysis显示文摘 | WRIGHT JL HOTALING J PORTER MP | 2009 | J Urol2009，181，3： | 1 |
| 9 | Predictors of upper tract urothelial cell carcinoma after primary bladder cancer: a population based analysis显示文摘 | WRIGHT JL HOTALING J PORTER MP | 2009 | J Urol2009，181，3： | 1 |
| 10 | The effect of preoperative dexamethasone on the immediate and delayed postoperative morbidity in children undergoing adenotonsillectomy 显示文摘 | Pappas ALS Sukhani R Hotaling A J | 1998 | Anesthesia & Analgesia1998，87，1： | 1 |
| 11 | Erectile dysfunction after radical prostatectomy:hemodynamic profiles and their correlation with the recovery of erectile function显示文摘 | Mulhall JP Slovick R Hotaling J | 2002 | J Urol2002，167，3： | 1 |
| 12 | Predictors of upper tract urothelial cell carcinoma after primary bladder cancer:a population based analysis显示文摘 | Wright J L Hotaling J Porter M P | 2009 | J Urol2009，181，： | 1 |
| 13 | Round spermatid injection into human oocytes:a systematic review and meta-analysis显示文摘Many azoospermic men do not possess mature spermatozoa at the time of surgical sperm extraction.This study is a systematic review and meta-analysis evaluating outcomes following round spermatid injection(ROSI),a technique which utilizes immature precursors of spermatozoa for fertilization.An electronic search was performed to identify relevant articles published through October 2018.Human cohort studies in English involving male patients who had round spermatids identified and used for fertilization with human oocytes were included.Fertilization rate,pregnancy rate,and resultant delivery rate were assessed following ROSI.Meta-analysis outcomes were analyzed using a random-effects model.Data were extracted from 22 studies involving 1099 couples and 4218 embryo transfers.The fertilization rate after ROSI was 38.7%(95%confidence interval[CI]:31.5%–46.3%),while the pregnancy rate was 3.7%(95%CI:3.2%–4.4%).The resultant delivery rate was low,with 4.3%of embryo transfers resulting in a delivery(95%CI:2.3%–7.7%).The pregnancy rate per couple was 13.4%(95%CI:6.8%–19.1%)and the resultant delivery rate per couple was 8.1%(95%CI:6.1%–14.4%).ROSI has resulted in clinical pregnancies and live births,but success rates are considerably lower than those achieved with mature spermatozoa.While this technique may be a feasible alternative for men with azoospermia who decline other options,couples should be aware that the odds of a successful delivery are greatly diminished and the prognosis is relatively poor. | Brent M Hanson Taylor P Kohn Alexander W Pastuszak Richard T Scott Jr Philip J Cheng James M Hotaling | 2021 | Asian Journal of Andrology2021，23，4： | 1 |
| 14 | Predictors of sperm recovery after cryopreservation n testicular cancer显示文摘我们的目的在有为生育力保藏的阴囊的癌症银行精子的人是识别改进 postthaw 精液的预言者优秀的。我们考察了 67 个人提供阴囊的细菌房间肿瘤(TGCT ) 的 173 件单个精液样品在在我们的第三级的大学医学中心的在 1994 和 2010 之间的 gonadotoxic 治疗前的 cryopreserved 精子。我们的主要结果措施是为更大的 postthaw 总数的独立预言者在有 TGCT 的人的能动计数(TMC ) 。有 NSGCT 的人是更可能的更年轻(P < 0.01 ) 并且有的高癌症舞台(II 或 III, P < 0.01 ) 与有 seminoma 的人相比。在我们的多重回归模型, NSGCT 组织学,密度坡度纯化的使用,和新鲜 TMC > 中部的新鲜 TMC 各个增加了比中部的 postthaw TMC 大的 postthaw TMC 的机会。有趣地,变老,先进癌症舞台(II 或 III ) ,快速的结冰协议,和活动性 enhancer 没在我们的模型显示出改进 postthaw TMC 的增加的机会。在结论,有 TGCT 或差的新鲜 TMC 的人应该考虑在 oncologic 治疗前保存另外的小瓶(至少 15 小瓶) 。密度坡度纯化应该习惯性地被用来与 TGCT 在人优化 postthaw TMC。评估癌症舞台和各种各样的 cryopreservation 技术的更大的、使随机化的研究被需要在与考虑富饶保藏并且优化 cryosurvival 的 TGCT 建议人帮助。 | James M Hotaling Darshan P Patel Christopher Vendryes Natalya A Lopushnyan Angela P Presson Chong Zhang charles H Muller Thomas J Walsh | 2016 | Asian Journal of Andrology2016，18，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员