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| 1 | 免疫鸡产生IgY抗体的技术显示文摘IgY技术正在成为生物技术领域和医药研究中的新热点 ,并且越来越得到国内同仁的重视。因为卵黄抗体 (IgY)化学性质稳定 ,产量高、成本低 ,以及动物种系距离的优势 ,更适于生产特异性抗体 ,具有开发功能性食品和新药的潜能。作为系列介绍的第二部分 ,本文详细介绍和探讨免疫鸡产生IgY抗体技术的主要技术环节和实践应用方面的具体信息 ,包括动物饲养 ,对鸡的免疫 ,抗体特性 ,IgY提取技术 ,鸡单克隆抗体的制备等方面。 | 张小莺 郑礼 Rüdiger Schade Horacio Raul Terzolo Hanibal Pablo Chacana Joanna Porankiewicz-Asplund | 2004 | 中国药理学通报2004，20，10： | 19 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Continuous-flow determination of reserpine by oxidation with periodate ion and catalysis by manganese(II) in solution or by an MnO2(s) reactor显示文摘 | VARMA S R MARTINEZ C J HORACIO A M | 1990 | Anal Chim Acta1990，233，： | 1 |
| 4 | Passive flow switching valves on a centrifugal microfluidic platform显示文摘 | JITAE K HORACIO K ROGER H R | 2008 | Sensors and Actuators B:Chemical2008，128，2： | 1 |
| 5 | Transmission electron microscopy of the induced damage by argon implantation in (111) HgCdTe at room temperature 显示文摘 | Myriam H Aguirre Horacio R Canepa Noemi E Walsoede Reca | 2002 | Journal of Applied Physics2002，92，10： | 1 |
| 6 | Resveratrol and trimethylated resveratrol protect from acute liver damage induced by CC14 in the rat 显示文摘 | HORACIO R MINEKO S VIVTOR T | 2008 | J Appl Toxicol2008，28，2： | 1 |
| 7 | Moxifloxacin versus levofloxacin against acute exacerba- tions of chronic bronchitis: The Latin American Cohort 显示文摘 | Juan Urueta-Robledo Horacio Ariza Jose R | 2006 | Respiratory Medicine2006，100，： | 1 |
| 8 | Solvent - free catalytic preparation of 1,1 - diacetates from aldehydes using a wells - dawson acid (H6P2W18 O62 · 24H2O) 显示文摘 | GUSTAVO P R HORACIO J T GRACIELA T B | 2003 | Tetrahedrom Letters2003，44，1： | 1 |
| 9 | Kinematics of 3-RPS parallel manipulators by means of screw theory 显示文摘 | Jaime G Horacio O Jose M R | 2008 | International Journal of Advanced Manu- facturingTechnology2008，36，56： | 1 |
| 10 | Short RC columns under bilateral load histories显示文摘 | Kyuichi M Horacio R James O J | 1984 | Journal of Structural Engineering1984，110，1： | 1 |
| 11 | RNAi-mediated gene silencing in a gonad organ culture to study sex determination mechanisms in sea turtle显示文摘 | Itzel S R Horacio M L Sarah L M | 2013 | Genes2013，4，2： | 1 |
| 12 | Determination of inorganic arsenic species by flow injection hydride generation atomic absorption spectrometry with variable sodium tetrahydroborate concentrations 显示文摘 | Mirna E S Horacio R B | 2004 | Spectrochimica Acta Part B2004，，59： | 1 |
| 13 | Passive flow switching valves on a centrifugal microfluidic platform显示文摘 | JITAE K HORACIO K ROGER H R | 2008 | Sensors and Actuators B:Chemical2008，128，2： | 1 |
| 14 | Enhancement of stochastic resonance: the role of non-Ganssian noises 显示文摘 | Fuentes M A Toral R Horacio S W | 2001 | Physica A2001，295，： | 1 |
| 15 | Effect of Dispersion on the Operation of a KTP Electro-optic Q-switch 显示文摘 | Ti Chuang Alan Hays D Horacio Verdun R | 1994 | Applied Optics1994，33，36： | 1 |
| 16 | Field trials of a vaccine against bovine mastitis l:evaluation in heifers 显示文摘 | Jose A G Aldo C A Horacio R | 2005 | J Dairy Sci2005，，80： | 1 |
| 17 | Behavior of amoxicillin in wastewater and river water: i- dentification of its main transformation products by liquid chro- matography/electrospray quadrupole time-of-flight mass spec- trometry 显示文摘 | Prrez-Parada Andr 6 s Agtiera Ana G 6 mez-Ramos Maria del Mar Garcfa-Reyes Juan F Heinzen Horacio Fern 6 ndez-Alba A- madeo R | 2011 | Rapid Communications in Mass Spectrometry2011，25，6： | 1 |
| 18 | Self-mixing technique for vibration meas- urements in a laser diode with multiple modes created by optical feedbackI显示文摘 | Marta R L Horacio L | 2009 | App ed Opt cs2009，48，15： | 1 |
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