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| 1 | Microstructural characteristics and mechanical behavior of B4Cp/6061Al composites synthesized at different hot-pressing temperatures显示文摘B4Cp/6061Al composites have become important structural and functional materials and can be fabricated by powder metallurgy and subsequent hot rolling. In this work, the effects of the hot-pressing temperature on microstructures and mechanical behaviors of the B4Cp/6061Al composites were investigated. The results showed that compared with the T4 heat treated B4Cp/6061Al composite hot pressed at 560℃, the yield strength and failure strain of the composites hot pressed at 580℃ were increased to 235 MPa and 18.4%, respectively. This was associated with the interface bonding strength between the B4C particles and the matrix. However, the reaction products, identified to be MgAl2O4 phases, were detected in the composites hot pressed at 600℃. The formation of the MgAl2O4 phases resulted in the Mg depletion, thus reducing the yield strength to 203.5 MPa after the T4 heat treatment due to the effect of the solid solution strengthening being weakened. In addition, the variation of hardness and electrical conductivity was mainly related to the Mg content in the matrix. Based on the as-rolled microstructures observed by SEM, SR-μCT and fracture surfaces, the deformation schematic diagram was depicted to reflect the tensile deformation process of the composites. | Minqiang Gao Zongning Chen Huijun Kang Enyu Guo Rengeng Li Ying Fu Honglan Xie Tongmin Wang | 2019 | Journal of Materials Science & Technology2019，35，8： | 4 |
| 2 | Thermal and elemental analysis of the combustion chamber deposits in a large-scale two-stroke marine diesel engine显示文摘It is of significance to understand the chemical content of carbon deposits in the large-scale two-stroke(LSTS) marine diesel engine because of adverse effect on the engine performance, oil consumption and emissions. In this work, two different combustion chamber deposits in an LSTS marine diesel engine were studied using thermogravimetry analysis(TGA), elemental analysis(EA) and synchrotron X-ray fluorescence(SXRF). One was on the piston top and the other on the piston land, termed PTCD and PLCD, respectively. For the PTCD sample, the 97% residue in the TGA and 1.4% carbon content in the EA indicated the main compositions of PTCD were metal salts or oxides and ashes, significantly different from the previous findings of the highest carbon content in deposits from the small four stroke engines. The different chemical content between PTCD and PLCD implied higher thermal load in the LSTS marine diesel engine led to a nearly complete thermal decomposition of PTCD. The higher calcium content in PTCD and PLCD indicated the additives of cylinder oil should be the main source of metal content of PTCD and PLCD. Calcium distribution in the SXRF results was indicative of the potential layered structure in PTCD and PLCD. In addition, the appearance of iron on the surface against the piston in PTCD and PLCD indicated iron oxides formation between carbon deposit and piston materials. | ZHANG XuSheng ZENG XiangMing SUN XiuCheng DENG Biao PENG GuanYun XIE HongLan WU ZhiJun XIAO TiQiao | 2015 | Science China(Technological Sciences)2015，58，10： | 2 |
| 3 | Observation of cavitation and water-refilling processes in plants with X-ray phase contrast microscopy显示文摘With the spatial coherence of X-rays and high flux and brightness of the 3rd generation synchrotron radiation facility,X-ray phase contrast microscopy(XPCM)at Shanghai Synchrotron Radiation Facility(SSRF)can provide high resolution dynamic imaging of low electron density materials in principle.In this paper,we investigated the cavitation and water-refilling processes in rice and bamboo leaves utilizing XPCM at SSRF.The occurrence of xylem cavitation was recorded in vivo.The study also revealed that under different dehydration conditions,cavitation occurs in different degrees,and therefore,the refilling process is different.The results demonstrate that SSRF can provide high enough fluxes to study dynamic processes in plants in real-time,and XPCM is expected to be a promising method to reveal the mechanisms of cavitation and its repair in plants nondestructively. | XUE Yanling XIAO Tiqiao DU Guoha TONG Yajun LIU Huiqiang DENG Biao XIE Honglan XU Hongjie | 2013 | Nuclear Science and Techniques2013，24，6： | 1 |
| 4 | Effects of the layer thickness ratio on the enhanced ductility of laminated aluminum显示文摘The layered structural parameters have been reported to be critical for tuning the tensile properties of laminated metals.Here,we investigated the effects of the thickness ratio(rc/f)of coarse-grained layers(CLs)to fine-grained layers(FLs)on the enhanced ductility of the laminated Al.The local strain evolution demonstrates that the strain delocalization ability of laminated Al is improved with the decrease of rc/f.The interfacial strain gradients,which can produce extra work hardening,gradually approach and cover the CLs with the rc/fdecreasing,explaining the trend of uniform elongation in laminated Al with various rc/f.The integrated fracture morphology characterization reveals that the increase of the rc/fleads to an improvement in the tolerance of the interfacial microcracks,which is corresponding to the variation of fracture elongation in the laminated Al.Moreover,there is an evident transition of transverse propagation path of interfacial microcracks from the CLs to FLs with increasing the rc/f.Based on a geometrical criterion of microcracks connectivity,the preferential transverse propagation path of interfacial microcracks in these laminated Al was rationalized.The calculation based on this criterion also predicted the critical rc/fcorresponding to the optimal combination of strength and fracture elongation.This work deepens the understanding of the role of structural parameters of laminated metals in achieving the strength and ductility synergy. | Yiping Xia Hao Wu Kesong Miao Xuewen Li Chao Xu Lin Geng Honglan Xie Guohua Fan | 2022 | Journal of Materials Science & Technology2022，，16： | 1 |
| 5 | The MORC2 p.S87L mutation reduces proliferation of pluripotent stem cells derived from a patient with the spinal muscular atrophy-like phenotype by inhibiting proliferation-related signaling pathways显示文摘Mutations in the microrchidia CW-type zinc finger protein 2(MORC2)gene are the causative agent of Charcot-Marie-Tooth disease type 2Z(CMT2Z),and the hotspot mutation p.S87L is associated with a more seve re spinal muscular atrophy-like clinical phenotype.The aims of this study were to determine the mechanism of the severe phenotype caused by the MORC2 p.S87L mutation and to explore potential treatment strategies.Epithelial cells were isolated from urine samples from a spinal muscular atrophy(SMA)-like patient[MORC2 p.S87L),a CMT2Z patient[MORC2 p.Q400R),and a healthy control and induced to generate pluripotent stem cells,which were then differentiated into motor neuron precursor cells.Next-generation RNA sequencing followed by KEGG pathway enrichment analysis revealed that differentially expressed genes involved in the PI3K/Akt and MAP K/ERK signaling pathways were enriched in the p.S87L SMA-like patient group and were significantly downregulated in induced pluripotent stem cells.Reduced proliferation was observed in the induced pluripotent stem cells and motor neuron precursor cells derived from the p.S87L SMA-like patient group compared with the CMT2Z patient group and the healthy control.G0/G1 phase cell cycle arrest was observed in induced pluripotent stem cells derived from the p.S87L SMA-like patient.MORC2 p.S87Lspecific antisense oligonucleotides(p.S87L-ASO-targeting)showed significant efficacy in improving cell prolife ration and activating the PI3K/Akt and MAP K/ERK pathways in induced pluripotent stem cells.Howeve r,p.S87L-ASO-ta rgeting did not rescue prolife ration of motor neuron precursor cells.These findings suggest that downregulation of the PI3K/Akt and MAP K/ERK signaling pathways leading to reduced cell proliferation and G0/G1 phase cell cycle arrest in induced pluripotent stem cells might be the underlying mechanism of the severe p.S87L SMA-like phenotype.p.S87L-ASO-targeting treatment can alleviate disordered cell proliferation in the early stage of pluripotent stem cell induction. | Sen Zeng Honglan Yang Binghao Wang Yongzhi Xie Ke Xu Lei Liu Wanqian Cao Xionghao Liu Beisha Tang Mujun Liu Ruxu Zhang | 2024 | Neural Regeneration Research2024，19，1： | 0 |
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