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9篇 您的检索式:作者名="Hiromi Yatsuji"
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1Hepatitis C virus enhances incidence of idiopathic pulmonary fibrosis显示文摘AIM: To investigate the cumulative development incidence and predictive factors for idiopathic pulmonary fibrosis in hepatitis C virus (HCV) positive patients. METHODS: We studied 6150 HCV infected patients who were between 40-70 years old (HCV-group). Another 2050 patients with hepatitis B virus (HBV) were selected as control (HBV-group). The mean observation period was 8.0 ± 5.9 years in HCV-group and 6.3 ± 5.5 years in HBV-group. The primary goal is the development of idiopathic pulmonary fibrosis (IPF) in both groups. The cumulative appearance rate of IPF and independent factors associated with the incidence rate of IPF were calculated using the Kaplan- Meier method and the Cox proportional hazard model. All of the studies were performed retrospectively by collecting and analyzing data from the patient records in our hospital. RESULTS: Fifteen patients in HCV-group developedIPF. On the other hand, none of the patients developed IPF in HBV-group. In HCV-group, the cumulative rates of IPF development were 0.3% at 10th year and 0.9% at 20th year. The IPF development rate in HCV-group was higher than that in HBV-group (P = 0.021). The IPF development rate in patients with HCV or HBV was high with statistical significance in the following cases: (1) patients ≥ 55 years (P < 0.001); (2) patients who had smoking index (package per day × year) of ≥ 20 (P = 0.002); (3) patients with liver cirrhosis (P = 0.042). CONCLUSION: Our results indicate that age, smoking and liver cirrhosis enhance the development of IPF in HCV positive patients.Yasuji Arase Fumitaka Suzuki Yoshiyuki Suzuki Norio Akuta Masahiro Kobayashi Yusuke Kawamura Hiromi Yatsuji Hitomi Sezaki Tetsuya Hosaka Miharu Hirakawa Satoshi Saito Kenji Ikeda Hiromitsu Kumada 2008World Journal of Gastroenterology2008,14,38:8
2Poor Response to Pegylated Interferon and Ribavirin in Older Women Infected with Hepatitis C Virus of Genotype 1b in High Viral Loads显示文摘Hitomi Sezaki Fumitaka Suzuki Yusuke Kawamura Hiromi Yatsuji Tetsuya Hosaka Norio Akuta Masahiro Kobayashi Yoshiyuki Suzuki Satoshi Saitoh Yasuji Arase Kenji Ikeda Yuzo Miyakawa Hiromitsu Kumada 2009Digestive Diseases and Sciences2009,,6:2
3Selection of a virus strain resistant to entecavir in a nucleoside-naive patient with hepatitis B of genotype H显示文摘Fumitaka Suzuki Norio Akuta Yoshiyuki Suzuki Hiromi Yatsuji Hitomi Sezaki Yasuji Arase Yusuke Kawamura Tetsuya Hosaka Masahiro Kobayashi Kenji Ikeda Mariko Kobayashi Sachiyo Watahiki Hiromitsu Kumada 2007Journal of Clinical Virology2007,,2:2
4Viral Elimination Reduces Incidence of Malignant Lymphoma in Patients with Hepatitis C显示文摘Yusuke Kawamura Kenji Ikeda Yasuji Arase Hiromi Yatsuji Hitomi Sezaki Tetsuya Hosaka Norio Akuta Masahiro Kobayashi Fumitaka Suzuki Yoshiyuki Suzuki Hiromitsu Kumada 2007The American Journal of Medicine2007,,12:2
5Extending Combination Therapy with Peginterferon plus Ribavirin for Genotype 2 Chronic Hepatitis C Virological Responders: A Pilot Study of 7 Cases显示文摘Akuta Norio Suzuki Fumitaka Arase Yasuji Hirakawa Miharu Kawamura Yusuke Yatsuji Hiromi Sezaki Hitomi Suzuki Yoshiyuki Hosaka Tetsuya Kobayashi Masahiro Kobayashi Mariko Saitoh Satoshi Ikeda Kenji Kumada Hiromitsu 2010Intervirology2010,,3:1
6Low risk of adefovir resistance in lamivudine-resistant chronic hepatitis B patients treated with adefovir plus lamivudine combination therapy: Two-year follow-up显示文摘Hiromi Yatsuji Fumitaka Suzuki Hitomi Sezaki Norio Akuta Yoshiyuki Suzuki Yusuke Kawamura Tetsuya Hosaka Masahiro Kobayashi Satoshi Saitoh Yasuji Arase Kenji Ikeda Sachiyo Watahiki Satomi Iwasaki Mariko Kobayashi Hiromitsu Kumada 2008Journal of Hepatology2008,,6:1
7Sustained virological response reduces incidence of onset of type 2 diabetes in chronic hepatitis C显示文摘Yasuji Arase Fumitaka Suzuki Yoshiyuki Suzuki Norio Akuta Masahiro Kobayashi Yusuke Kawamura Hiromi Yatsuji Hitomi Sezaki Tetsuya Hosaka Miharu Hirakawa Kenji Ikeda Hiromitsu Kumada 2009Hepatology2009,,3:1
8An Open Pilot Study Exploring the Efficacy of Fluvastatin, Pegylated Interferon and Ribavirin in Patients with Hepatitis C Virus Genotype 1b in High Viral Loads显示文摘Sezaki Hitomi Suzuki Fumitaka Akuta Norio Yatsuji Hiromi Hosaka Tetsuya Kobayashi Masahiro Suzuki Yoshiyuki Arase Yasuji Ikeda Kenji Miyakawa Yuzo Kumada Hiromitsu 2009Intervirology2009,,1:1
9Virological Response and Hepatocarcinogenesis in Lamivudine-Resistant Hepatitis B Virus Genotype C Patients Treated with Lamivudine plus Adefovir Dipivoxil显示文摘Akuta Norio Suzuki Fumitaka Kawamura Yusuke Yatsuji Hiromi Sezaki Hitomi Suzuki Yoshiyuki Hosaka Tetsuya Kobayashi Masahiro Kobayashi Mariko Arase Yasuji Ikeda Kenji Kumada Hiromitsu 2009Intervirology2009,,:1
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